Please click on the study name for recruitment information or the consortium name to go to the consortium's website.
Clinical Islet Transplantation Consortium (CIT) : The goal of the CIT02 studies is to determine the proportion of subjects who are insulin independent after a single islet cell infusion at 75 ± 5 days post-transplant in subjects treated with Exenatide or Lisofylline added to a standard islet transplant regimen.
Study Names: Strategies to Improve Long Term Islet Graft Survival, B-Lymphocyte Immunotherapy in Islet Transplantation, Efficacy of Islet after Kidney Transplantation , Peritransplant Deoxyspergualin in Islet Transplantation in Type 1 Diabetes, Islet Transplantation in Type 1 Diabetes with LEA29Y Maintenance Therapy, Islet Transplantation in Type 1 Diabetes
Family Investigation of Nephropathy and Diabetes (FIND) : The main goal of this consortium is to acquire sets of families with well-characterized diabetic nephropathy, in order to perform a genome scan to identify chromosomal regions linked with diabetic nephropathy.
Study Name: Family Investigation of Nephropathy and Diabetes
Search for Diabetes in Youth (SEARCH ) : A population-based registry to define the prevalence and incidence of diabetes in children of diverse racial and ethnic backgrounds by diabetes type.
Study Name: SEARCH for Diabetes in Youth
The Environmental Determinants of Diabetes in the Young (TEDDY) : This study is identifying infants at high-risk for developing type 1 diabetes and following them through adolescence in the search for environmental factors that may trigger disease onset.
Study Name: The Environmental Determinants of Diabetes in the Young
Trial to Reduce IDDM in the Genetically at Risk (TRIGR) : This randomized, double blinded intervention study is comparing the development of type 1 diabetes in infants who are weaned onto a hydrolysate of cow’s milk formula, in which many of the cow proteins have been broken down, versus standard cow’s milk formula.
Study Name: Trial to Reduce IDDM in those at Genetic Risk
Type 1 Diabetes Genetics Consortium (T1DGC) : This consortium is recruiting families in order to develop resources for the scientific community to identify genes influencing an individual’s risk for developing type 1 diabetes.
Study Name: Type 1 Diabetes Genetics Consortium
Type 1 Diabetes TrialNet (TrialNet) : This network supports clinical trials of agents to slow the progression of type 1 diabetes in new-onset patients and to prevent the disease in at-risk patients.
Study Names: TrialNet-MMF/DZB, TrialNet Natural History Study, The Rituximab Study, Nutritional Intervention to Prevent Diabetes , Oral Insulin Study , TEST, test, CTLA-4 Ig (Abatacept) in Recent Onset Diabetes