[BMCT Membership Roster] [BMCT Meeting Rosters]

The Basic Mechanisms of Cancer Therapeutics [BMCT] Study Section reviews applications addressing the mechanisms of action of anti-neoplastic agents, including drug effects on tumor cell growth, death, and differentiation. Studies analyzing the mechanisms of resistance to anti-neoplastic agents and the circumvention of resistance to cancer drugs are also included. Specific areas covered by BMCT:

• Mechanism(s) of action of anti-neoplastic agents or combinations of agents at the molecular, cellular, or target tissue level
• Mechanism(s) of action of chemosensitizing agents or angiogenesis inhibitors or  combinations with anti-neoplastic chemotherapeutic agents
• Mechanism(s) of resistance to anti-neoplastic agents and strategies for circumvention of resistance
• Effect of anti-neoplastic agents on tumor cell anabolic processes including: macromolecular synthesis, DNA repair, gene regulation, immortalization, differentiation, cell cycle and checkpoint control, RNA translation, and signal transduction
• Effect of anti-neoplastic agents on tumor cell catabolic processes including: DNA damage, apoptotic and non-apoptotic cell death, protein degradation, protein stability, and stress-response pathways

The study sections with most closely related areas of similar science listed in rank order are:

Drug Discovery and Molecular Pharmacology Study Section [DMP] 
Developmental Therapeutics Study Section [DT] 
Cancer Molecular Pathobiology Study Section [CAMP] 
Radiation Therapeutics and Biology [RTB] 
Clinical Neuroimmunology and Brain Tumors Study Section [CNBT]