[MONC Membership Roster] [MONC Meeting Rosters]

The Molecular Oncogenesis [MONC] Study Section reviews applications that focus on the early molecular events that lead to immortalization and oncogenic transformation such as the identification of oncogenes and tumor suppressor genes, alterations in signaling, growth, and cell cycle control pathways, and protein stability/degradation mechanisms. Applications dealing with normal developmental processes as they pertain to oncogenic transformation, including the identification and characterization of progenitor and cancer stem cells are also considered. Specific areas covered by MONC:

• Identification of oncogenes and tumor suppressor genes or alterations in their expression, regulation or function that may contribute to oncogenic transformation
• Alterations in signal transduction pathways that may modulate or lead to oncogenic transformation
• Identification and characterization of progenitor cells and cancer stem cells that may be involved in oncogenic transformation
• Cell cycle regulation and dysregulation that may contribute to early oncogenic transformation
• Proteasome-mediated degradation: Mechanisms and/or alterations of protein stability that could contribute to transformation, including post-translation modification such as ubiquitylation or sumoylation

The study sections with the most closely related of similar science listed in rank order are:

Cancer Molecular Pathobiology Study Section [CAMP] 
Tumor Cell Biology Study Section [TCB] 
Cancer Etiology Study Section [CE] 
Cancer Genetics Study Section [CG] 
Cellular Signaling and Regulatory Systems Study Section [CSRS]