[NOMD Membership Roster] [NOMD Meeting Rosters]

The NOMD Study Section reviews applications studying programmed cell death, necrosis and excitotoxicity; analysis of cloned gene products involved in cell survival or death; reactive oxygen species and oxidative stress associated with neural injury; and mitochondrial biology of neurons and glia in healthy and diseased states across the life span. Also considered are the roles of genetic factors, trophic molecules and extrinsic influences [including toxins, hormones, and addictive or environmental substances] in these processes, as well as basic aspects of disease, injury, repair and interventional strategies. Specific areas covered by NOMD:

• Regulation of neuronal cell death and cell survival; functions and mechanisms of action of signaling molecules [such as neurotrophic factors, growth factors, cytokines, glutamate] and electrical activity in regulating cell survival. Intracellular signaling pathways leading to apoptosis, necrosis and excitotoxicity, and their intersection with the signal transduction pathways of survival factors.
• Oxidative stress; special metabolic and energy demands of neurons and glia; relevant aspects of mitochondrial function and localization; aspects of mitochondrial dysfunction in disease states including Alzheimer’s disease, Parkinson’s disease and stroke.
• Mechanisms of neuronal cell death due to aging, disease, injury and environmental or genetic factors.  This could include excitotoxins, glutamate, free radicals, metals, and neurodegenerative disease genes, as well as elucidation of excitotoxic, necrotic, and apoptotic mechanisms.
• Studies of mechanisms relevant to the development of neuroprotective or cell survival strategies, such as the administration of exogenous growth factors, or antioxidants.
• Molecular mechanisms underlying neural injury associated with ischemia, reperfusion injury, traumatic brain injury, hypoxia, hypoglycemia, and excitotoxicity.

Study sections with most closely related areas of science listed in rank order are:

Cellular and Molecular Biology of Neurodegeneration Study Section [CMND]
Cell Death in Neurodegeneration Study Section [CDIN]
Clinical Neuroscience and Neurodegeneration Study Section [CNN]
Cellular Mechanisms in Aging and Development Study Section [CMAD]
Cellular and Molecular Biology of Glia Study Section [CMBG]