David Goldstein, MD
Entry Id: TP-9

Overview
The Clinical Neurocardiology Section carries out mainly patient-oriented clinical research on the diagnosis, mechanisms and treatment of neurocardiologic disorders. We study catecholamine systems, focusing on biomarkers and mechanisms of Parkinson’s disease and related disorders. Measurement techniques include cardiovascular reflexes, neuropharmacologic manipulations, neurochemical assays, and positron emission tomographic imaging. The section runs a world-renowned Clinical Neurochemistry Laboratory.

Structure of the Clinical Training Program
Clinical investigations are under the supervision of Dr. David Goldstein, whose interests include developing neurocardiology as a clinical discipline in medicine, integrative approaches for understanding the roles of catecholamines in organismic homeostasis, and linking molecular genetics with integrative physiology, based on evolving understanding of catecholamine systems. His main areas of expertise are in clinical neurocardiology, autonomic function testing, positron emission tomographic scanning, and catecholamine neurochemistry.

Examples of Papers Authored by Program Faculty

• Goldstein, DS. Adrenaline and the Inner World:  An Introduction to Scientific Integrative Medicine. Baltimore:  The Johns Hopkins University Press, 2006.
• Goldstein DS, Smith LJ. The NDRF Handbook for Patients with Dysautonomias. New York:  Future, 2002.
• Goldstein DS. The Autonomic Nervous System in Health and Disease. New York: Marcel Dekker, Inc., 2001.
• Goldstein DS. Stress, Catecholamines, and Cardiovascular Disease. New York: Oxford University Press, 1995.

Qualified candidates for a Clinical Fellowship position (with privileges in the NIH Clinical Center) should have:

• Board certification in internal medicine or neurology;
• Be licensed to practice medicine in the United States;
• Have an interest in patient-oriented clinical research; and
• Have a serious interest in one of the above scientific topics.

Qualified candidates for a Pre-Clinical Fellowship position should:

• Have an advanced degree in biochemistry, neurochemistry, physiology, or similar subject matter; and
• Have a serioud interest in one of the above scientific topics.

The NIH is dedicated to building a diverse community in its training and employment programs.