Jordan Grafman, PhD
Entry Id: TP-46

Overview
The focus of research in the Cognitive Neuroscience Section is planning, reasoning, executive functions and their breakdown in patients with lesions to the prefrontal cortex and related cortical and subcortical structures; memory and amnesia; neuroplasticity; knowledge representation and cognitive architectures and their dissolution in neurological disease; visual attention, object recognition, and visuomotor learning. The operating framework to study these processes and their disorders is cognitive science although we combine this approach with state-of-the-art clinical neuroscience techniques such as Positron-Emission Tomography, functional MRI, and Single-Pulse & Repetitive Transcranial Magnetic Stimulation. The Cognitive Neuroscience Section is housed in the NIH Clinical Center. The Section's state-of-the-art equipment, facilities, numerous resources, and collaborative faculty provide ample opportunity for the development of innovative research and broad cognitive neuroscience experience. The Section is currently studying patients with Degenerative Dementias, Parkinson's Disease, Stroke, Cerebellar Disease, Stroke, Epilepsy, Penetrating and Closed Head Injury, Progressive Supranuclear Palsy, and Cortico-basal-degeneration.

Structure of the Clinical Training Program
The training program is designed as a 2-3 year experience that includes weekly neurology clinical and grand rounds, Section presentations and discussions, tutorial training, and the teaching of skills necessary to conduct a clinical neurobehavioral examination.

The Section has a firm and continuing commitment to increasing the participation of historically underrepresented groups in cognitive neuroscience.

Structure of the Research Training Program
The training program is designed as a 2-3 year experience that includes weekly journal club presentations; research rounds; tutorial training in cognitive science, neuroimaging, and neuropsychological methods; the development of experiments in one or more areas of cognitive neuroscience; and supervision of the production of manuscripts reporting the results of your experiments.

• Grafman, J., Schwab, K., Warden, D., Pridgen, A., Brown, H.R., Salazar, A.M. Frontal Lobe Injuries, Violence, and Aggression: A Report of the Vietnam Head Injury Study. Neurology, 46 (5), 1231-1238. 1996.
• Sadato, N., Pascual-Leone, A., Grafman, J., Ibanez, V., Deiber, M.-P., Dold, G., Hallett, M. Activation of the Primary Visual Cortex by Braille Reading in Blind Subjects. Nature, 380 (11 April), 526-528, 1996.
• Pascual-Leone, A., Grafman, J., Hallett, M. Explicit and Implicit Learning and Maps of Cortical Motor Output (technical report). Science, 265 (9 September, 1994),1600-1601.
• Grafman, J., Pascual-Leone, A., Alway, D., Nichelli, P., Gomez-Tortosa, E., Hallett, M. Induction of Recall Deficits in a Verbal Memory Task by Left Temporal and Dorsofrontal Rapid-Rate Transcranial Magnetic Stimulation. Neuroreport, 5 (9), 1157-1160, 1994.
• Nichelli, P., Grafman, J., Pietrini, P., Alway, D., Carton, J.C., Miletich, R. Brain Activation During Chess Deliberation. Nature, 369 (6477), 19 May, 191, 1994.

Program Graduates

• Jeffrey Hadley, Ph.D.; Johns Hopkins University School of Public Health, Baltimore, Maryland
• Marten Scheffers; Department of Psychology, University of Illinois, Champaign, Illinois
• Angela Sirigu, Ph.D.; INSERM U. 289, Hopital Salpetriere, Paris, France
• Mark Beeman, Ph.D.; Dept. of Neurology, Rush Neuroscience Institute, Rush-Presbyterian-St. Lukes Hospital, Chicago, Illinois
• Ildebrando Appollonio, M.D.; Department of Neurology, Hospital S. Gerardo, University of Milano, Monza, Italy
• Paolo Nichelli, M.D.; Dept. of Neurology, Clinica di Neurologia, Modena, Italy
• Linda Rueckert, Ph.D.;Northeastern State University, Chicago, Illinois
• Vinod Goel, Ph.D.; York University, Toronto, Canada
• Arnaud Partiot, M.D., Ph.D.; Lilly Pharmaceuticals, Paris, France
• Rhonda Friedman, Ph.D.; Department of Neurology, Georgetown University, Washington, D.C.
• Tim Rickard, Ph.D.; Department of Psychology, University of California-San Diego
• Stephen Flitman, M.D.; Department of Neurology, Barrow Neurological Institute

Neurologists or Psychiatrist who have completed residency training approved by either the ACGME or Amer. Board of Neurology and who are board eligible or board certified are eligible to apply. Prior research training with relevant publications in U.S. or Western European medical journals is desirable.

Electronic Application
The quickest and easiest way to find out more about this training program or to apply for consideration is to do it electronically.

The NIH is dedicated to building a diverse community in its training and employment programs.