Edmund Talley, Ph.D.

Edmund (Ned) Talley joined the NINDS in 2005 as a Program Director for Channels, Synapses and Circuits. His program at the NINDS is focused on basic research in synaptic transmission and neuromodulation. Dr. Talley received his Ph.D. in 2001 from the University of Virginia, where he studied the physiology and pharmacology of motor neurons involved in respiration. After his Ph.D., he remained at UVA as a Research Assistant Professor, and initiated investigations into the CNS functions of two-pore-domain potassium channels, with an emphasis on their modulation by neurotransmitters and clinically important drugs. His work on these channels included extensive mapping of their CNS expression patterns, identification of molecular bases for their modulation using mutational and biochemical analyses, and investigations into their functions in vivo by generating knockout mouse lines.