| Topic: |
hematologic diseases (he) |
| Title: |
Hematopathological Concepts and Controversies in the Diagnosis and Classification of Myelodysplastic Syndromes. |
| Author: |
Vardiman, J.W. |
| Source: |
IN: Hematology 2006. Washington, DC: American Society of Hematology. 2006. pp 199-204. |
| Availability: |
Available from American Society of Hematology. 1900 M Street NW, Suite 200, Washington, DC 20036. Email: ASH@hematology.org. Website: www.asheducationbook.org. Price: Available free on website. |
| Abstract: |
Although the diagnosis and classification of most cases of the myelodysplastic syndromes (MDS) are usually accomplished without difficulty, a minority of cases may pose diagnostic problems. This article explores hematopathological concepts and controversies in the diagnosis and classification of MDS. The author contends that, in many cases, the diagnostic dilemma can be solved by adhering to basic guidelines recommended for evaluation of patients suspected of having MDS, and in particular to the quality of the blood and bone marrow specimens submitted for morphologic, immunophenotypic and genetic studies. In other cases, such as patients who have hypocellular MDS or MDS with fibrosis, the criteria for making a diagnosis may be difficult if not impossible to apply. The author presents data to illustrate that the World Health Organization (WHO) classification offers a valuable tool in the diagnosis and classification of MDS. 1 table. 34 references. |
| Format: |
Monograph/Book |
| Language: |
English. |
| Major Keywords: |
Hematologic Diseases. Myelodysplastic Syndromes. Diagnosis. Classification. Diagnostic Tests. Patient Care Management. |
| Minor Keywords: |
Complications. Patient Selection. Blood Testing. Bone Marrow. Genetics. Immune System. Fibrosis. Pathology. Guidelines. |
| Publication Number: |
HEBK10071. |
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