Biosketch

Bradford Wood is a Senior Investigator with Tenure at NIH. He earned both his undergraduate and graduate degrees from The University of Virginia, then completed an Internship in Internal Medicine, followed by Residency in Diagnostic Radiology at Georgetown University, where he was Chief Resident. He then went on to do double fellowships at Massachusetts General Hospital at Harvard in Abdominal Imaging and Intervention and Vascular & Interventional Radiology, and stayed on staff at Massachusetts General Hospital / Harvard after training, and holds his Certificate of Added Qualifications in Vascular and Interventional Radiology.

Dr. Wood was recruited by John Doppman to the NIH in 1998, and has practiced here in Interventional Radiology since. He directed the Interventional Radiology Research Lab from 2004 to present, and was Acting Chief of Radiology - Science and Research and Acting Director of the Molecular Imaging Lab from 2006 to 2008, when he became a Tenured Senior Investigator. He also is an Adjunct Investigator in the National Cancer Institute, and is credentialed in surgery and radiology. He has received both the Clinical Center Director’s Award and the NIH Director’s Award, and has published widely in the field of Interventional Radiology and the emerging discipline in Interventional Oncology.

His accolades include All-American in Lacrosse, multiple patents in the field, and pioneering several technologies from the bench to the patient, now in widespread use, including heat-deployed chemotherapy as well as a “Medical GPS” system for image-guided procedures. His research interests include drug + device combination therapies, heat deployed nanoparticle vectors, GPS-smart medical devices, minimally-invasive & image-guided tumor ablation, high intensity focused ultrasound, molecular interventions, and the Operating Room of the Future. He was the first physician to perform radiofrequency ablation mono-therapy for kidney tumors in humans in the mid-1990’s, the first to use ablation devices plus heat deployed drugs, and the first to guide ablation with GPS-enabled devices.

He is actively involved in the Society of Interventional Radiology, the Radiological Society of North America, the European Society of Radiology, the Center of Interventional Oncology, the NCI working groups on Image Guided Drug Delivery and on Biomarkers, and the SIR Interventional Oncology Task Force. He serves on journal editorial boards, including the Journal of Interventional Oncology, reviews for numerous journals in multiple disciplines, is on the Board of the International Society for Therapeutic Ultrasound, and has been a visiting professor and invited faculty at institutions around the world.

Selected Publications

Dr. Wood has published extensively in the field, coauthoring a book on radiology, over 155 manuscripts and chapters, over 200 scientific abstracts, and 17 patents or patent applications to date.

BOOKS AND BOOK CHAPTERS

Wood BJ, Wood SD. Radiology (House-officer’s Handbook Series). 1st Edition. Williams & Wilkins, Baltimore 1998

Wood BJ, Neeman Z, Kam A: New Technologies in Tumor Ablation. in Tumor Ablation: Principles and Practice. E vanSonnenberg, W McMullen (editors). 2006

Sudheendra D, Wood BJ: Thermal Ablation of Adrenal Tumors: in Image Guided Interventions. Matt Mauro, Kieran Murphy, Ken Thomson, Tony Venbrux and Chris Zollikofer (editors), Elsevier, New York, 2006

Cleary K, Buersmeyer T, Wood BJ, Glossop N: Computer Aided Surgery, in: Wiley Encyclopedia of Biomedical Engineering. Metin Akay (editor), John Wiley and Sons, Inc. 2006

JOURNAL ARTICLES

Wood BJ, Ramkaransingh JR, Fojo T, Walther MM, Libutti SK: Percutaneous Tumor Ablation with Radiofrequency. Cancer 2002; 94:443-451

Neeman Z, Wood BJ: Interventional oncology: Radiofrequency ablation beyond the liver. Tech Vasc Interv Radiol 2002; 5:156-163

Wood BJ, Abraham J, Hvizda JL, Alexander HR, Fojo T: Radiofrequency Ablation of Adrenal Tumors and Adrenocortical Carcinoma Metastases. Cancer 2003, 97:554-60

Hwang JJ, Walther MM, Pautler SE, Coleman JA, Hvizda J, Peterson J, Linehan WM, Wood BJ: Radio frequency ablation of Small Renal Tumors: Intermediate Results. J Urology 2004;171:1814-1818

Pingpank JF, Libutti SK, Chang R, Wood BJ, Neeman Z, Kam AW, Figg WD, Zhai SP, Beresneva T, Seidel GD, Alexander HR: Phase I Study Of Hepatic Arterial Melphalan Infusion And Hepatic Venous Hemofiltration Using Percutaneously Placed Catheters In Patients With Unresectable Hepatic Malignancies. J Clin Oncol 2005;23:3465-3474

Wood BJ, Zhang H, Durrani A, Glossop N, Ranjan S, Lindisch D, Levy E, Banovac F, Borgert J, Krueger S, Kruecker J, Viswanathan A, Cleary K: Navigation with Electromagnetic Tracking for Interventional Radiology Procedures: A Feasibility Study. J Vasc Interven Radiol 2005;16: 493-505

Stone M, Wood BJ: Emerging Local Ablation Techniques: in Special Review: Hepatic Malignancies. Seminars in Vascular and Interventional Radiology 2006;23:425-428

Sudheendra D, Barth M, Hegde U, Wilson W, Wood BJ: Radiofrequency Ablation of Lymphoma. Blood 2006;107:1624-1626

Dromi S, Frenkel V, Luk A, Traughber B, Angstadt M, Bur M, Poff J, Xie J, Libutti SK, Li KCP, Wood BJ: Pulsed-high intensity focused ultrasound and low temperature sensitive liposomes for enhanced targeted drug delivery and anti-tumor effect. Clin Cancer Res 2007;13:2722-2727

Wood BJ, Locklin JK, Viswanathan A, Kruecker J, Haemmerich D, Cebral J, Sofer A, Cheng R, McCreedy E, Cleary K, McAuliffe MJ, Glossop N, Yanof J: Technologies for Guidance of Radiofrequency Ablation in the Multimodality Interventional Suite of the Future. J Vasc Interv Radiol 2007;18:9-24

Stone MJ, Frenkel V, Dromi S, Thomas P, Lewis RP, Li KCP, Horne M 3rd, Wood BJ: Pulsed-high intensity focused ultrasound enhanced tPA mediated thrombolysis in a novel in vivo clot model, a pilot study. Thrombosis Research 2007;121:193-202

Krücker J, Xu S, Glossop N, Viswanathan A, Borgert J, Schulz H, Wood BJ: Electromagnetic tracking for thermal ablation and biopsy guidance: clinical evaluation of spatial accuracy. J Vasc Interv Radiol 2007;18:1141-1150

Singh A, Kruecker J, Xu S, Glossop N, Guion P, Ullman K, Choyke P, Wood BJ: Initial Clinical Experience with Real Time Ultrasound-MRI Fusion-Guided Prostate Biopsy. British Journal of Urology International 2008;101:841-845

Stone MJ, Venkatesan AM, Locklin J, Pinto P, Linehan M, Wood BJ: Radiofrequency ablation of renal tumors. Tech Vasc Interv Radiol 2007; 10:132-9

Dromi SA, Herby S, Walsh M, Dreher M, Xie J, Fry T, Wood BJ: Radiofrequency Ablation Induces Antigen Presenting Cell Infiltration and Amplification of Weak Tumor-Induced Immunity, Radiology 2008