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Trus, BL, Newcomb, WW, Cheng, N, Cardone, G, Marekov, L, Homa, FL, Brown, JC, Steven, AC, "Allosteric Signalling and a Nuclear Exit Strategy: Binding of UL25/UL17 Heterodimers to DNA-filled HSV-1 Capsids" Mol. Cell (2007)   [Abstract] [Full Article]

Freidlin R.Z, Ohazama C.J., Arai A.E., McGarry D.P., Panza J.A., Trus B.L. "NIHmagic: 3D Visualization, Registration and Segmentation Tool"   [Full Article]

McAuliffe MJ, Eberly D, Fritsch DS, Chaney EL, and Pizer SM. "Scale-Space Boundary Evolution Initialized by Cores." Proceedings of the Fourth International Conference on Visualization in Biomedical Computing, Lecture Notes in Comp Sci Vol 1131, KH Hohne and R Kikinis (eds), Springer. pp. 173-182, 1996.

McAuliffe MJ, Eberly D, Fritsch DS, Chaney EL, and Pizer SM. "Scale-Space Boundary Evolution Initialized by Cores." Proceedings of the Fourth International Conference on Visualization in Biomedical Computing, Lecture Notes in Comp Sci Vol 1131, KH Hohne and R Kikinis (eds), Springer. pp. 173-182.

Yim PJ, Marcos HB, McAuliffe MJ, McGarry D, Heaton Ian, Choyke PL. "Registration of Time-Series Contrast Enhancement Magnetic Resonance Images for Renography." IEEE Computer-Based Medical Systems (CBMS) pp. 516-520.

Fritsch DS, Chaney EL, Boxwala A, McAuliffe MJ, Raghavan S, Thall A, and Earnhart JD. "Core-based Registration for Automatic Radiotherapy Treatment Verification." International Journal of Radiation Oncology, Biology, Physics. 33 (5), pp. 1287-1300, December 1995.

Yim PJ, Marcos HB, McAuliffe MJ, McGarry D, Heaton Ian, Choyke PL. "Registration of Time-Series Contrast Enhancement Magnetic Resonance Images for Renography." IEEE Computer-Based Medical Systems (CBMS) pp. 516-520. July 2001.

Baggett D, McAuliffe M, Lockett S. "Whole Cell Segmentation in Solid Tissue Sections." Cytology

Muanza TM, Cotrim A, McAuliffe MJ, Sowers AL, Baum BJ, Cook JA, Feldchtein F, Amazeen PG, Colman CN, Mitchell JB. "Evaluation of Radiation-Induced Oral Mucositis by Optical Coherence Tomography." Clinical Cancer Research Vol. 11 pp 5221-5127. July 2005

McCreedy ES, Cheng R, Hemler P, Viswanathan A, Wood B, McAuliffe MJ. "Radio Frequency Ablation Registration, Segmentation, and Fusion Tool." IEEE Computer-Based Medical Systems (CBMS) pp. 259-264. June 2005.

Jia, G, Baudendistel KT, von Tengg-Kobligk H, Heverhagen JT, Polzer H, Henry H, McAuliffe MJ, Levine AL, Rosol TJ, Knopp MV. "Assessing Prostate Volume by Magnetic Resoance Imaging, A Comparison of Different Measurement Approaches for Organ Volume Analysis." Investigative Radiology. Volume 40, pp. 243-248. April 2005.

Bazin PL, Gandler W, McAuliffe, MJ, Pham DL. "A Software Tool for Atlas-based Volumetric Neuroimage Analysis." International Symposium on Medical Imaging, SPIE. Volume 5747. pp 1824-1833. April 2005

Steven AC, Heymann JB, Cheng N, Trus BL, Conway JF "Virus maturation: dynamics and mechanism of a stabilizing structural transition that leads to infectivity" Curr Opin Struct Biol. 15(2):227-36   [PubMed]

Trus BL, Cheng N, Newcomb WW, Homa FL, Brown JC, Steven AC "Structure and polymorphism of the UL6 portal protein of herpes simplex virus type 1." J Virol. 78(22):12668-71   [PubMed]

Trus BL, Newcomb WW, Cheng N, Brown J, Steven AC "Structure of the HSV-1 Portal Protein by Electron Microscopy." 13th European Microscopy Congress. 3: 295-296

Unser M, Sorzano CO, Thevenaz P, Jonic S, El-Bez C, De Carlo S, Conway JF, Trus BL "Spectral signal-to-noise ratio and resolution assessment of 3D reconstructions." J Struct Biol. 149(3):243-55   [PubMed]

Sorzano C, Jonic S, Bez EE, Carlo SD, Thevenaz P, Conway J, Trus BL, Unser M "Volumetric spectral signal-to-noise ratio." 13th European Microscopy Congress. 1:427-8

Kuszewski J, Schwieters CD, Garrett DS, Byrd RA, Tjandra N, Clore GM "Completely automated, highly error-tolerant macromolecular structure determination from multidimensional nuclear overhauser enhancement spectra and chemical shift assignments." J Am Chem Soc. 126:6258-73   [PubMed]

Iwahara J, Schwieters CD, Clore GM "Characterization of non-specific protein-DNA interactions by 1H paramagnetic relaxation enhancement." J Am Chem Soc. 2004 Oct 13; 126(40):12800-8   [PubMed]

Iwahara J, Schwieters CD, Clore GM "Ensemble approach for NMR structure refinement against (1)H paramagnetic relaxation enhancement data arising from a flexible paramagnetic group attached to a macromolecule." J Am Chem Soc. 126:5879-96

Hemler P, McCreedy ES, McAuliffe MJ "Performance comparison of a new liver vessel segmentation algorithm." International Symposium on Medical Imaging, SPIE 2004 5370:1785-94

Davison AJ, Trus BL, Cheng N, Steven AC, Watson MS, Cunningham C, Le Deuff RM, Renault T "A novel class of herpesvirus with bivalve hosts." J Gen Virol. 86(1):41-53    [PubMed]

Clore GM, Schwieters CD "Amplitudes of protein backbone dynamics and correlated motions in a small alpha/beta protein: correspondence of dipolar coupling and heteronuclear relaxation measurements." Biochemistry 43:10678-91   [PubMed]

Clore GM, Schwieters CD "How much backbone motion in ubiquitin is required to account for dipolar coupling data measured in multiple alignment media as assessed by independent cross-validation?" J Am Chem Soc. 126:2923-38   [PubMed]

Newcomb WW, Homa FL, Thomsen DR, Booy FP, Trus BL, Steven AC, Spencer JV, Brown JC "Assembly of the Herpes Simplex Virus Capsid: Characterization of Intermediates Observed During Cell-free Capsid Formation." Molecular Biology 432-446    [PubMed]

Newcomb WW, Homa FL, Thomsen DR, Trus BL, Cheng N, Steven AC, Booy FP, Brown JC. "Assembly of the Herpes Simplex Virus Procapsid from Purified Components and Identification of Small Complexes Containing the Major Capsid and Scaffolding Proteins." Virology 73, No.5: 4239-4250    [PubMed]

Newcomb WW, Trus BL, Cheng N, Steven AC, Sheaffer AK, Tenney DJ, Weller SK, Brown JC "Isolation of Herpes Simplex Virus Procapsids from Cells Infected with a Protease-Deficient Mutant Virus." Virology 74, No.4: 1663-1673    [PubMed]

Vivino MA, Mahurkar A, Trus B, Lopez ML, Datiles M "Quantitative analysis of retroillumination images." Eye 9:77-84   [PubMed]

Vivino M, Laurienzo J, Curiel R, Panza J "Impact of gain settings on the relation between concentration of ultrasound scatterers and video intensity: implications for clinical studies using myocardial contrast echocardiography." Presentation at the American College of Cardiology Meeting Orlando, FL, 931-119

Vivino M "NIH image and ocular imaging." Ninth Annual Research Symposium presentation at the American Academy of Optometry (AAO) Annual meeting in New Orleans, LA

Trus BL, Unser M, Vrhel MJ, Conway JF, Gross M, Threvenaz P, Steven AC "Resolution assessment of 3D reconstructions by spectral signal-to-noise ratio." EUREM Proc. Dublin, Ireland.

Trus BL, Roden RBS, Greenstone HL, Schiller JT, Booy FP "3D reconstruction of bovine papillomavirus visualized at 9¿." Conf. on Virus Assembly Saxtons River, VT

Trus BL, Roden RBS, Greenstone HL, Schiller JT, Booy FP "3D reconstruction of bovine papillomavirus visualized at 9¿." Proc. of XIIth International Biophysics Congress in Progress in Biophysics and Molecular Biology 65(1):28.

Trus BL, Kocsis E, Conway JF, Steven AC "Digital image processing of electron micrographs: The PIC system III." J. Struct. Biol. 116:61-67   [PubMed]

Trus BL, Homa FL, Thomsen DR, Newcomb WW, Booy FP, Brown JC, Steven AC "Visualization of herpesvirus capsids assembled in a recombinant baculovirus system by cryo-electron microscopy." Proceedings of the 13th International Congress on Electron Microscopy

Trus BL, Homa FL, Thomsen DR, Newcomb WW, Booy FP, Brown JC, Steven AC "HSV capsid protein VP26 is absent from pentons: difference mapping between VP26 + and VP26 - capsids assembled in a recombinant baculovirus system." Biophys. J. 68(2):A20.

Trus BL, Greenstone HL, Roden RBS, Schiller JT, Booy FP "Localization of two neutralizing antibodies on bovine papillomavirus." Proceedings of the XIV International Phage/Virus Assembly Conference Gibson U, Hendrix R, Russel M. Johnstown, PA

Trus BL, Davison AJ, Booy FP, Steven AC "Capsid structure of channel catfish virus, and evolutionarily distant herpesvirus, by cryo-electron microscopy." Proceedings of the 52th Microscopy Society of America Bailey, G.W.

Trus BL, Booy FP, Newcomb WW, Brown JC, Homa FL, Thomsen DR, Steven AC "The herpes simplex virus procapsid: structure, conformational changes upon maturation, and roles of the triplex proteins VP19c and VP23 in assembly." J. Mol. Biol 263(3):447-62   [PubMed]

Trus BL "Image processing in electron microscopy: High performance computing applied to biological systems." The Second Workshop on Advanced Computing for Biological Imaging Carragler B, Potter C, Urbana-Champaign, IL

Steven AC, Booy FP, Trus BL, Newcomb WW, Homa FL, Thomsen DR, Brown JC "Visualization of the conformational changes that accompany maturation of the herpesvirus procapsid." EUREM Proc. August, Dublin, Ireland.

Martino RL, Johnson CA, Suh EB, Trus BL, Yap TK "Parallel computing in biomedical research." Science 265:902-8   [PubMed]

Martino RL, Johnson CA, Kempner KM, Pohida TJ, Powell JI, Suh EB, Trus BL, Yap TK "Providing Computational Science and Engineering Expertise for a Large Biomedical Research Program." The First Joint Meeting of the Biomedical Engineering Society and the IEEE Engineering in Medicine and Biology Society Atlanta, Georgia, October 1999

Lanczycki CJ, Johnson CA, Trus BL, Conway JF, Steven AC, Martino RL "Parallel computing applications for the structural biology of viruses." IEEE Computational Science and Engineering 5:76-9

Kocsis E, Cerritelli ME, Trus BL, Cheng N, Steven AC "Improved methods for determination of rotational symmetries in macromolecules." Ultramicroscopy 60:219-228   [PubMed]

Kessel M, Maurizi MR, Kim B, Trus BL, Kocsis E, Singh SK, Steven AC "Oligomeric Structure of the Clp-AP Protease from E. coli." Proceedings of the 95th General Meeting of the American Society of Microbiology Washington, D.C.

Kessel M, Maurizi RR, Kim B, Kocsis E, Trus BL, Singh SK, Steven AC "Homology in structural organization between E. coli ClpAP protease and the eukaryotic 26 S proteasome." J. Mol. Biol. 250(5):587-94   [PubMed]

Kessel M, Kim B, Trus BL, Kocsis E, Singh SK, Maurizi M, Steven AC "Oligomeric structure of the Clp-AP protease from E. coli." Biophys. J. I 68 (suppl 2):A245.

Iwasaki K, Trus BL, Wingfield PT, Cheng N, Campusano G, Rao VB, Steven AC "Molecular Architecture of Bacteriophage T4 Capsid: Vertex Structure and Bimodal Binding of the Stabilizing Accessory Protein, Soc." Virology 321-333    [PubMed]

Spencer JV, Trus BL, Booy FP, Steven AC, Newcomb WW, Brown JC "Structure of the Herpes Simplex Virus Capsid: Peptide A862-H880 of the Major Capsid Protein Is Displayed on the Rim of the Capsomer Protrusions." Virology 229-235    [PubMed]

Johnson CA, Weisenfeld NI, Trus BL, Conway JF, Martino RL, Steven AC "Orientation determination in the 3-D reconstruction of icosahedral viruses using a parallel computer." Proceedings of Supercomputing 1994 902-8

Johnson CA, McGarry D, Cook JA, Subramanian S, Devasahayam N, Mitchell JM, Krishna MC "Maximum entropy reconstruction methods in electron paramagnetic resonance imaging." Annals of Operations Research

Caston JR, Trus BL, Booy FP, Wickner RB, Wall JS, Steven AC "Structure of L-A Virus: A Specialized Compartment for the Transcription and Replication of Double-stranded RNA." Cell Biology 138:975-985    [PubMed]

Caston JR, Belnap DM, Steven AC, Trus BL "A Strategy for Determining the Orientations of Refractory Particles for Reconstruction from Cryo-Electron Micrographs with Particular Reference to Round, Smooth-Surfaced, Icosahedral Viruses." Structural Biology 125:209-215    [PubMed]

Heck DV, Trus BL, Steven AC "Three-dimensional structure of bordetella pertussis fimbriae." J. Struc. Biol. 116:264-269   [PubMed]

Booy FP, Roden RB, Greenstone HL, Schiller JT, Trus BL "Two Antibodies that Neutralize Papillomavirus by Different Mechanisms Show Distinct Binding Patterns at 13 A Resolution." Molecular Biology 95-106    [PubMed]

Belnap DM, McDermott BM, Filman DJ, Cheng N, Trus BL, Zuccola HJ, Racaniello VR, Hogle JM, Steven AC "Three-dimensional structure of poliovirus receptor bound to poliovirus." Proc Natl Acad Sci U S A 97(1):73-8    [PubMed]

Belnap DM, Filman DJ, Trus BL, Cheng N, Booy FP, Conway JF, Curry S, Hiremath CN, Tsang SK, Steven AC, Hogle JM "Molecular Tectonic Model of Virus Structural Transitions: the Putative Cell Entry States of Poliovirus." Virology 74, No.3: 1342-1354    [PubMed]

Datiles M, Mahurkar A, Caruso R, Vivino M, Magno B "Effect of nuclear cataracts on visual function: cone threshold measurements using computer assisted perimetry." ARVO abstracts No.3483,S759

Conway JF, Trus BL, Booy FP, Newcomb WW, Brown JC, Steven AC "Visualization of three-dimensional density maps reconstructed from cryo-electron micrographs of viral capsids." J. Struct. Biol. 116:200-208   [PubMed]

Caston JR, Trus BL, Booy FP, Dinman JD, Wickner RB, Steven AC "Structural aspects of the capsid of L-A dsRNA virus of yeast." Proceedings of the XIV International Phage/Virus Assembly Conference Gibson U, Hendrix R, Russel M, Johnstown, PA, 6.

Booy FP, Trus BL, Davison AJ, Steven AC "The capsid architecture of channel catfish virus, an evolutionarily distant herpesvirus, is argely conserved in the absence of discernible sequence homology with herpes simplex virus." Virology 215:134-141   [PubMed]

Booy FP, Greenstone JL, Roden RS, Schiller JT, Steven AC, Trus BL "High resolution studies of papillomavirus and herpes simplex virus." EUREM Proc. Dublin, Ireland

Trus BL, Gibson W, Cheng N, Steven AC "Capsid Structure of Simian Cytomegalovirus from Cryoelectron Microscopy: Evidence for Tegument Attachment Sites." Virology 73, No.3: 2181-2192    [PubMed]

Steven AC, Belnap D, Cheng N, Conway JF, Trus BL "Viral Metamorphosis: Visualization Capsid Proteins and their Maturation." EUREM 12 Brno, Czech Republic, July 9-14, 2000 1:B339-342

Iwasaki K, Trus BL, Wingfield PT, Cheng N, Campusano G, Rao V, Steven AC "Morphogenesis of bacteriophage T4 capsid as studied by cryo-electron microscopy and 3D image reconstruction." EUREM 12 Brno, Czech Republic, July 7-14, 2000 1:B343-344

Trus BL, Heymann JB, Nealon K, Cheng N, Newcomb WW, Brown JC, Kedes DH, Steven AC "Capsid structure of Kaposi’s sarcoma-associated herpesvirus, a gammaherpesvirus, compared to those of an alphaherpesvirus, herpes simplex virus type 1, and a betaherpesvirus, cytomegalovirus." J Virol 75(6):2879-90    [PubMed]

Trus BL "Reconstruction of electron paramagnetic resonance images." SPIE International Symposium on Medical Imaging 4322:24-29

McAuliffe MJ, Lalonde F, McGarry DP, Gandler W, Csaky K, Trus BL "Medical Image Processing, Analysis & Visualization in Clinical Research." 14th IEEE Symposium on Computer-Based Medical Systems (CBMS 2001) 381-386

Belnap DM, Cheng N, Majeed S, Tsang SK, Filman DJ, McDermott Jr. BM, Trus BL, Kwong PD, Racaniello VR, Hogle JM, Steven AC "Poliovirus-Receptor Interaction and Conformational Changes During Cell Entry." XVII Biennail Conf on Phage and Virus Assembly June 30-July 5, 2001, Helsinki, Finland 2001:22

Trus BL, Yamada K, Subramanian S, Cook J, Devasahayam N, Mitchell J, Krishna M "Improved Quantitation of the Redox State Using Maximum Entropy Methods in Electron Parametric Resonance Imaging." First SIAM Conference on Imaging Science 2002:28

Seidel J, Vacquero JJ, Pascua J, Desco M, Johnson CA, Green M "Features of the NIH ATLAS Small Animal PET Scanner and Its Use with a Coaxial Small Animal Volume CT Scanner." IEEE International Symposium on Biomedical Imaging Washington, DC, 2002:TP-P1.9

Modis Y, Trus BL, Harrison SC "Atomic model of the papillomavirus capsid." EMBO 21:4754-62   [PubMed]

Johnson CA, Cook JA, McGarry DP, Devasahayam N, Mitchell JB, Subramanian S, Krishna M "Maximim Entropy Reconstruction Methods in Electron Paramagnetic Resonance Imaging." Annals of Operations Research 119 (1-4): 101-118

Johnson CA, Seidel J, Vaquero JJ, Pascau J, Desco M, Green MV "Exact Positioning for OSEM Reconstructions on the ATLAS Depth-of-Interaction Small Animal Scanner." Academy of Molecular Imaging Annual Conference 2002 San Diego, CA

Heymann JB, Trus BL, Cheng N, Newcomb WW, Brown JC, Steven AC "Dynamic Visualization of HSV Capsid Maturation." ICEM 15:1-6

Heymann JB, Trus BL, Cheng N, Newcomb WW, Brown JC, Steven AC "Herpes Simplex Virus Capsid Maturation Visualized by time-Lapsed Cryo-EM." Microsc. Microanal 8 (Suppl 2), 844CD-845CD

Green M, Seidel J, Johnson CA, Vaquero JJ, Pascua J, Desco M "Towards High Performance Small Animal Positron Emission Tomography." IEEE International Symposium on Biomedical Imaging Washington, DC, 2002 TA-SS-1.3

Clore GM, Kuszewski J "Chi(1) rotamer populations and angles of mobile surface side chains are accurately predicted by a torsion angle database potential of mean force." J Am Chem Soc 124:2866-7   [PubMed]

Clore GM, Schwieters CD "Theoretical and computational advances in biomolecular NMR spectroscopy." Curr Opin Struct Biol 12:146-53   [PubMed]

Cheng N, Trus BL, Belnap DM, Newcomb WW, Brown JC, Steven AC "Handedness of the herpes simplex virus capsid and procapsid." J Virol 76:855-9   [PubMed]

Yim PJ, McAuliffe MJ, Nosher JL "Reduction of Intra-Observer Variability of Tumor-Volume Measurement Using the Fuzzy C-Means Algorithm." Radiological Society of North America

Wood BJ, Yanof JH, McAuliffe MJ, Renisch S, Hvizda JL, Cleary K "PET-CT Treatment Planning Interface for Robot-Assisted Biopsy and Tumor Ablation." Radiological Society of North America

Wood BJ, Hvizda J, Yanof JH, Renisch S, Bitter I, McAuliffe MJ "Intra-Procedural Real-Time Registration and Fusion of Ultrasound and CT Image-Guided Percutaneous Liver Procedures." Radiological Society of North America

Schwieters CD, Kuszewski JJ, Tjandra N, Clore GM "The Xplor-NIH NMR molecular structure determination package." J Magn Reson 160:65-73   [PubMed]

Schwieters CD, Clore GM "Reweighted Atomic Densities to Represent Ensembles of NMR Structures." J. Biomol. NMR 23:221-225   [PubMed]

Heymann JB, Cheng N, Newcomb WW, Trus BL, Brown JC, Steven AC "Dynamics of herpes simplex virus capsid maturation visualized by time-lapse cryo-electron microscopy." Nat Struct Biol 10:334-41   [PubMed]

Clore GM, Schwieters CD "Docking of protein-protein complexes on the basis of highly ambiguous intermolecular distance restraints derived from 1H/15N chemical shift mapping and backbone 15N-1H residual dipolar couplings using conjoined rigid body/torsion angle dynamics." J Am Chem Soc 125:2902-12   [PubMed]

Clore GM, Kuszewski J "Improving the accuracy of NMR structures of RNA by means of conformational database potentials of mean force as assessed by complete dipolar coupling cross-validation." J Am Chem Soc 125:1518-25   [PubMed]

Cerritelli ME, Trus BL, Smith CS, Cheng N, Conway JF, Steven AC "A second symmetry mismatch at the portal vertex of bacteriophage T7 8-fold symmetry in the procapsid core." J Mol Biol 327: 1-6   [PubMed]

Cerritelli ME, Conway JF, Cheng N, Trus BL, Steven AC "Molecular Mechanisms in Bacteriophage T7 Procapsid Assembly, Maturation, and DNA Containment." In Advances in Protein Chemistry Vol 64, Virus Structure. Chiu W, Johnson J, eds. Academic Press (Amsterdam, The Netherlands) 301-324   [PubMed]