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Sensitivity and Specificity by Indication for Examination for 714,984 Diagnostic Mammography Examinations from 1996 - 2005

  Work-Up of Abnormal Screening Examination Short-Interval Follow-Up Evaluation of Breast Problem/No lump or Lump Unknown Evaluation of Breast Problem/Palpable Lump All Diagnostic Examinations
Sensitivity* 88.1% 59.8% 75.1% 87.1% 82.4%
True positives 9,013 1,482 4,023 6,847 21,365
Cancers 10,234 2,477 5,358 7,858 25,927
Specificity§ 89.0% 96.8% 95.5% 92.1% 93.2%
True negatives|| 197,940 155,492 188,273 100,236 641,941
Non-Cancers# 222,444 160,678 197,132 108,803 689,057

Note: 23,653 (5.2%) examinations were given an initial BI-RADS assessment of zero. The first non-zero assessment within 180 days was used as the final assessment for analysis. Examinations without a non-zero assessment within 180 days were excluded (N=7,943; 1.7%).

* Sensitivity = the percentage of cancers that had an abnormal interpretation (BI-RADS category 4 or 5).

True Positive = the number of cancers that had an abnormal interpretation (BI-RADS category 4 or 5).

Cancers = the number of examinations with a tissue diagnosis of cancer within 1 year following the examination.

§ Specificity = the percentage of non-cancers that had a negative interpretation (BI-RADS category 1, 2, or 3).

|| True Negative = the number of non-cancers that had a negative interpretation (BI-RADS category 1, 2, or 3).

# Non-cancers = the number examinations without a tissue diagnosis of cancer within 1 year following the examination.

The following source must be cited when reproducing this table: NCI-funded Breast Cancer Surveillance Consortium co-operative agreement (U01CA63740, U01CA86076, U01CA86082, U01CA63736, U01CA70013, U01CA69976, U01CA63731, U01CA70040). Downloaded xx/xx/xx from the Breast Cancer Surveillance Consortium Web site - http://breastscreening.cancer.gov/data/benchmarks/diagnostic/tableSensSpec.html

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