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Home » About the NTP » Federal Register Notices » CERHR solits comments on 11 chemicals
[Federal Register: March 20, 2000 (Volume 65, Number 54]
[Notices]
[Pages 14997-14998]
DEPARTMENT OF HEALTH AND HUMAN SERVICES
PUBLIC HEALTH SERVICE
National Toxicology Program; National Institute of Environmental Health Sciences; Center for the Evaluation of Risks to Human Reproduction solicits comments on eleven chemicals being considered for further evaluation by the Center; solicits nominations of other chemicals for future consideration; and describes the Center's evaluation process.
Background
The National Toxicology Program (NTP) and the National Institute of Environmental Health Sciences have established the NTP Center for the Evaluation of Risks to Human Reproduction (63 FR 68782, No 239). The purpose of the Center is to provide timely and unbiased, scientifically sound evaluations of human and experimental evidence for adverse effects on reproduction, including development, caused by agents to which humans may be exposed. The goals of the individual assessments are to (1) interpret for and provide to the general public information about the strength of scientific evidence that a given exposure or exposure circumstance poses a hazard to reproduction and the health and welfare of children: (2) provide regulatory agencies with objective and scientifically credible assessments of reproductive/development health effects associated with exposure to specific chemicals or classes of chemicals, including descriptions of any uncertainties associated with the assessment of risks, and (3) identify knowledge gaps to help establish research and testing priorities.
Chemicals Recommended for Further Consideration
The CERHR Core Committee, made up of representatives of NTP-participating agencies, reviewed chemical nominations for further study and recommended the following eleven chemicals for further consideration. Dossiers will be prepared on these chemicals reviewing information on their use, production volume, and general, reproductive, and developmental toxicity. Selection of candidate chemicals will be based upon production volume, extent of human exposures, public concern about chemical hazard, published evidence of reproductive or developmental toxicity, and evaluation of any additional information submitted by the public in response to this announcement. The chemicals to be considered for Expert Panel evaluation in the year 2000 are listed below with their Chemical Abstracts Service registry numbers (where available).
1-Bromopropane (106-94-5)
2-Bromopropane (75-26-3)
Dimethyl Methyl Phosphonate (DMMP) (756-79-6)
Ethylene glycol (107-21-1)
Glycol ethers (not available)
Glyphosate (1071-83-6)
Methanol (67-56-1)
Nicotine (54-11-5)
Phenol (108-95-2)
Thimerosal (54-64-8)
Toluene (108-88-3)
Request for Public Comment on Candidate Chemicals
The Center invites public comment on the candidate chemicals listed above, including toxicology information from completed or ongoing studies, and information on planned studies, as well as current production data, human exposure information, use patterns, and environmental occurrence. Written comments received May 4, 2000, will be considered in the review. Please forward comments and chemical information to: Dr. John Moore, CERHR, 1800 Diagonal Road, Suite 500, Alexandria, VA 22314-2808, Phone: (703) 838-9440.
Request for Nominations for Future Reviews
Nominations of chemicals for future evaluations are also encouraged. Any individual or organization may nominate. Nominations should include the chemical name, Chemical Abstract Service registry number (if known), reason for the nomination, and references or articles on the chemical, when possible. The nominator's name, address, telephone number and e-mail address should be included with the nomination. Nominations can be made through the Center's website or by mail to Dr. John Moore at the address listed above.
Review Process
The Center's review process is outlined below:
Further information about the NTP Center for the Evaluation of Risks to Human Reproduction can be obtained through the Center's website: http://cerhr.niehs.nih.gov or by contacting:
Michael D. Shelby, Ph.D. |
or |
John A. Moore, D.V.M., |
Dated: March 10, 2000
Kenneth Olden, P.D.
Director, NIEHS.
[Billing Code 4140-01-P]
Web page last updated on October 04, 2004
The National Institute of Environmental Health Sciences is one of the National Institutes of Health within the U.S. Department of Health and Human Services. The National Toxicology Program is headquartered on the NIEHS campus in Research Triangle Park, NC.