Administrative Supplements for Making Knockout Mice

Description:
The attendees at an international meeting convened at the Banbury Conference Center in Cold Spring Harbor, New York, in the fall of 2003 strongly supported the establishment of a focused, large-scale international effort to produce a publicly available, comprehensive collection of mouse knockout alleles. Meeting participants also felt that improving access to existing resources would avoid unnecessary duplication of efforts. Since the Banbury meeting, significant progress has been made toward generating the mutant resource envisioned by the attendees. Several gene-targeting consortia have been funded to complete the mouse mutant resource. Also, a mouse repository at the University of California, Davis has been established where embryonic stem (ES) cells and mice can be obtained by the research community. In recognition of the research community's keen interest in utilizing knockout mice in research programs and to optimize usage of the extensive resource now available to the research community, several National Institutes of Health Institutes and the Knockout Mouse Project re-announce the opportunity for investigators to apply for administrative supplements to have mouse knockouts made from existing mutant ES cell resources. The goal of the program is to support the use of existing resources and to ensure that ES cell lines are converted into frozen embryos that are available from a repository.

Web Site:

Contact:
Dr. Cheryl Marks; cm74v@nih.gov

This page last updated 2008-02-28 12:25:01