NIH Clinical Research Studies Listed By Institute of the Principal Investigator

National Eye Institute (NEI)

40 Protocols (35 Active Accrual of new subjects, 5 Follow-up of previously enrolled subjects)


Active Accrual, Protocols Recruiting New Patients 
* 09-EI-0008:
Pilot Study of the Evaluation of Subconjunctival Sirolimus in the Treatment of Bilateral Geographic Atrophy Associated with Age-Related Macular Degeneration

* 08-EI-0175:
Pilot Study of the Evaluation of Sirolimus in the Treatment of Diabetic Macular Edema

* 08-EI-0169:
Evaluation and Treatment Protocol for Potential Research Participants with Ocular Diseases

* 08-EI-0147:
Pilot Study of Intravitreal Injection of Ranibizumab for Macular Telangiectasia without Neovascularization (MACTEL 2)

* 08-EI-0146:
Pilot Study of Intravitreal Injection of Ranibizumab for Macular Telangiectasia with Neovascularization (MACTEL 1)

* 08-EI-0135:
Pilot Validation Study of Computer Administration of Vision Targeted Quality of Life Instruments

* 08-EI-0129:
Pilot Study of Sunitinib Malate for Advanced Ocular Disease of Von Hippel-Lindau Syndrome

* 08-EI-0103:
High Speed Indocyanine Green Angiography Findings in Induction / PRN Regimen of Intravitreal Ranibizumab Injection for Neovascular Age-Related Macular Degeneration

* 08-EI-0102:
Screening Study for the Evaluation and Diagnosis of Potential Research Participants

* 08-EI-0099:
Epigenetics, Molecular Genetics, and Biomarkers of Degenerative and Inflammatory Ocular Diseases

* 08-EI-0061:
Pilot Study for the Detection of Neutralizing Antibodies in Patients treated with Bevacizumab (Avastin™ (Trademark)) or Ranibizumab (Lucentis™ (Trademark))

* 08-EI-0043:
Age-Related Eye Disease Study (AREDS) Follow-Up

* 08-EI-0031:
Visual Motor Coordination

* 07-EI-0145:
Ocular Impact of X Chromosome Karyotype and Sex Hormones in Turner Syndrome and Premature Ovarian Failure

* 06-EI-0252:
A Novel Non-Invasive In Vivo Imaging System to Measure Retinal Metabolism

* 06-EI-0236:
National Ophthalmic Genotyping Network Stage 1 - Creation of DNA Repository for Inherited Ophthalmic Diseases

* 06-EI-0230:
Family Studies of Uveal Coloboma

* 06-EI-0111:
Treatment of Choroidal Subretinal Neovascularization with Agents Directed Against the Immune Response

* 06-EI-0068:
The Vitreous Proteome and Inflammatory Mediators in Ocular Inflammatory Disease

* 06-EI-0059:
Clinical and Molecular Studies in Families with Glaucoma and Related Diseases

* 06-EI-0058:
Clinical and Molecular Studies in Families with Myopia and Related Diseases

* 06-EI-0050:
Multicenter Uveitis Steroid Treatment (MUST) Trial Protocol

* 05-EI-0143:
Molecular Genetics of Retinal Degenerations

* 05-EI-0104:
Familial Exudative Vitreoretinopathy Clinical and Molecular Studies

* 05-EI-0096:
Natural History and Genetic Studies of Usher Syndrome

* 04-EI-0008:
Clinical and Molecular Studies in Families With Corneal Dystrophy or Other Inherited Corneal Diseases

* 03-EI-0255:
Pilot Study on the Effect of Vitamin A Supplementation on Cone Function in Retinitis Pigmentosa

* 03-EI-0155:
Evaluation of Single Nucleotide Polymorphism (SNP) in Patients with and Subjects without Age-Related Macular Degeneration (AMD)

* 03-EI-0123:
Clinical and Molecular Studies in Families with Congenital or Hereditary Cataracts

* 03-EI-0122:
Evaluation of Immune Responses to Different Antigens in Non Infectious Ocular Inflammatory Diseases

* 03-EI-0033:
X-Linked Juvenile Retinoschisis - Clinical and Molecular Studies

* 01-EI-0046:
Evaluation and Treatment of Corneal and External Diseases and Anterior Segment Disorders

* 00-EI-0135:
Study of Association of Serum Factors with Diabetic Retinopathy

* 92-EI-0113:
Immunopathology and Molecular Pathology of Ocular Diseases in Humans

* 86-EI-0062:
Trial of Topical Cysteamine in the Treatment of Corneal Cystine Crystal Accumulation in Cystinosis

Active Follow-up, Protocols NOT Recruiting New Patients 

* 07-EI-0213:
LI/National Eye Institute Repository

* 07-EI-0025:
The Age-Related Eye Disease Study 2 (AREDS2): A Multi-Center, Randomized Trial of Lutein, Zeaxanthin, and Omega-3 Long-Chain Polyunsaturated Fatty Acids (Docosahexaenoic Acid [DHA] and Eicosapentaenoic Acid [EPA]) in Age-Related Macular Degeneration

* 06-EI-0116:
A Phase II Study of OT-551 Antioxidant Eye Drop in Participants with Bilateral Geographic Atrophy Associated with Age-Related Macular Degeneration

* 06-EI-0046:
Treatment of Non-Infectious Intermediate and Posterior Uveitis Associated Macular Edema with Humanized Anti-CD11a Antibody Therapy

* 05-EI-0002:
A Phase I Clinical Trial to Study the Safety of a Sustained-Release Subconjunctival Cyclosporine Implant for Ocular Graft-vs-Host Disease (GVHD1)

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