NIH Clinical Research Studies Listed By Institute of the Principal Investigator

National Institute of Neurological Disorders and Stroke (NINDS)

146 Protocols (118 Active Accrual of new subjects, 28 Follow-up of previously enrolled subjects)

Active Accrual, Protocols Recruiting New Patients 
* 00-N-0095:
Brain Activation During Developmental Speech Production and Speech Perception

* 00-N-0089:
Genetic Analysis of the Chiari I Malformation

* 00-N-0082:
Characterization of Brain Activation at 1.5 and 3.0 Tesla Using Perfusion Images and Blood Oxygen Level Dependent Images

* 00-N-0057:
Positron Emission Tomography Imaging of Activation-Induced Signal Transduction in Human Brain

* 00-N-0043:
Clinical and Molecular Manifestations of Inherited Neurological Disorders

* 99-N-0178:
Feasibility of Neuromuscular Stimulation for Laryngeal Elevation During Swallowing

* 99-N-0045:
Study of Abnormal Acquired and Genetic Coagulation Factors in Children with Porencephaly and Stroke

* 99-N-0009:
Sensory Function in Idiopathic Voice Disorders

* 98-N-0047:
Immuno-Virological Evaluation of Human T Cell Leukemia Virus Type-1 Associated Myelopathy (HAM/TSP)

* 97-N-0070:
Training Protocol for Various Sleep Disorders in Patients with Neurological Disorders

* 96-N-0089:
Characteristics of Idiopathic Familial Voice Disorders

* 96-N-0088:
Characteristics of Idiopathic Familial Speech Disorders

* 93-N-0202:
Diagnosis and Natural History Protocol for Patients with Different Neurological Conditions

* 92-N-0226:
Establishing the Physiology of Syringomyelia

* 89-N-0045:
Evaluation of Progression in Multiple Sclerosis by Magnetic Resonance Imaging (MRI)

* 85-N-0195:
A Training Protocol for the use of Botulinum Toxin in the Treatment of Neurological Disorders

* 81-N-0010:
Regional Cerebral Utilization of Glucose in Patients with a Diagnosis of Frontal Lobe Dementia, Atypical Parkinsonian Disorder, and Other Basal Ganglia Disorders

* 76-N-0021:
Combined Clinical, Immunological and Virological Assessment of Patients with Multiple Sclerosis (MS)

Active Follow-up, Protocols NOT Recruiting New Patients 

* 09-N-0010:
Biomarkers of Risk of Parkinson Disease

* 08-N-0045:
Investigation of the Dopamine System in Frontotemporal Dementia

* 07-N-0139:
Cross-Validating NIRS with fMRI

* 07-N-0014:
The Use of Magnetic Resonance Imaging to Investigate Cortical Damage in Patients with Multiple Sclerosis and Correlation with Cognitive Dysfunction

* 06-N-0243:
Brain Connectivity Between Visual Input and Motor Output

* 06-N-0139:
Treatment for Psychogenic Movement Disorders

* 06-N-0113:
Phase II Clinical Trial to Examine the Efficacy and Safety of Dutasteride in Patients with Kennedy's Disease (Spinal and Bulbar Muscular Atrophy)

* 06-N-0096:
Testing Objective Measures of Motor Impairment in Early Parkinson's Disease

* 05-N-0245:
A Six Month Double-Blind, Placebo-Controlled Phase 2 Clinical Trial to Determine the Safety and Efficacy of Idebenone Administered to Patients with Friedreich's Ataxia

* 05-N-0092:
Clinical Trial Characterizing the Bioavailability of 1-Octanol in Adults with Ethanol-responsive Essential Tremor

* 05-N-0075:
Evaluation of the Mechanism of NO Formation and Pharmacokinetics of Long-Term Intravenous Nitrite Infusion in Healthy Volunteers

* 05-N-0036:
Recombinant Human Interferon Beta-1a in Acute Ischemic Stroke: A Dose Escalation and Safety Study

* 05-N-0018:
The Functional Anatomy of Personality Trait Knowledge: an fMRI Study

* 04-N-0287:
Efficacy of Rituximab in Patients with Stiff Person Syndrome with Anti-GAD Antibodies: A Randomized Placebo-Controlled Trial

* 04-N-0247:
Treatment Study for Frontotemporal Dementia

* 04-N-0192:
The Role of the Prefrontal Cortex in Economic Decision-Making in Reciprocal Trust Games Using Functional Hyperscanning Neuroimaging

* 04-N-0146:
fMRI Study on Mechanism of Rhythm Perception and Generation

* 04-N-0059:
Sensorimotor Gating Studies in Restless Legs Syndrome

* 04-N-0019:
Zenapax (daclizumab) Admin to Pts with Multiple Sclerosis (ZAP MS): Effect of Intravenously Admin Humanized Monoclonal Antibody against the Interleukin-2 Receptor Alpha Subunit (Daclizumab) on Inflammatory Activity in the Central Nervous System

* 04-N-0016:
Non-Invasive Seizure Localization in Patients with Medically Refractory Localization Related Epilepsy: Synchronized MEG-EEG Recordings

* 03-N-0203:
SMN Levels in Peripheral Blood Samples of SMA Patients and the Effects of Pharmacological Compounds In Vitro

* 02-N-0301:
ReoPro Retavase Reperfusion of Stroke Safety Study-Imaging Evaluation with Computed Tomography (ROSIE-CT)

* 02-N-0182:
Quantitative fMRI in Children and Adults Using Arterial Spin Tagging Techniques

* 02-N-0175:
Study of Tics in Patients with Tourette's Syndrome and Chronic Motor Tic Disorder with [15O]H2O PET in Awake and in Sleep States

* 02-N-0154:
ReoPro Retavase Reperfusion of Stroke Safety Study - Imaging Evaluation

* 00-N-0140:
A Prospective Natural History Study of VHL Patients with CNS Hemangioblastomas

* 99-N-0169:
Effect of the Humanized Monoclonal Antibody Against the Interleukin-2 Receptor Alpha Subunit (IL-2R-Alpha; Zenapax® (Registered Trademark)) on Inflammatory Activity in the CNS in MS in a Baseline-to-Treatment, Cross-Over, MRI-Controlled Single Cente

* 92-N-0246:
Gene Therapy for the Treatment of Brain Tumors Using Intra-Tumoral Transduction with the Thymidine Kinase Gene and Intravenous Ganciclovir

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