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NIA Intramural Research Program 1998 Publications

Adams, C.S., Horton, W.E., Jr.: Chondrocyte apoptosis increases with age in the articular cartilage of adult animals. Anat Rec 250: 418-25, 1998. [Abs] Ajmani, R.S., Rifkind, J.M.: Hemorheological changes during human aging. Gerontology 44: 111-20, 1998. [Abs] Akar, C.A. and Wallace, W.C.: Amyloid precursor protein modulates the interaction of nerve growth factor with p75 receptor and potentiates its activation of trkA phosphorylation. Brain Res Mol Brain Res 56: 125-32, 1998. [Abs] Alexandroff, A.B., McIntyre, C.A., Porter, J.C., Zeuthen, J., Vile, R.G., Taub, D.D.: Sticky and smelly issues: lessons on tumour cell and leucocyte trafficking, gene and immunotherapy of cancer. Br J Cancer 77: 1806-11, 1998. [Abs] Anderson, D.E.: Cardiorenal effects of behavioral inhibition of breathing. Biol Psychol 49: 151-63, 1998. [Abs] Anderson, D.E., Dhokalia, A., Parsons, D., Bagrov, A.Y.: Sodium sensitivity in young adults with high resting end-tidal CO2. J Hypertens 16: 1015-22, 1998. [Abs] Anson, R.M., Croteau, D.L., Stierum, R.H., Filburn, C., Parsell, R., Bohr, V.A.: Homogenous repair of singlet oxygen-induced DNA damage in differentially transcribed regions and strands of human mitochondrial DNA. Nucleic Acids Res 26: 662-8, 1998. [Abs] Archer, R.P., Fontaine, J., McCrae, R.R.: Effects of two MMPI-2 validity scales on basic scale relations to external criteria. J Pers Assess 70: 87-102, 1998. [Abs] Asai, O., Longo, D.L., Tian, Z.G., Hornung, R.L., Taub, D.D., Ruscetti, F.W., Murphy, W.J.: Suppression of graft-versus-host disease and amplification of graft- versus-tumor effects by activated natural killer cells after allogeneic bone marrow transplantation. J Clin Invest 101: 1835-42, 1998. [Abs] Atack, J.R., Rapoport, S.I., Schapiro, M.B.: Cerebrospinal fluid production is normal in Down syndrome. Neurobiol Aging 19: 307-9, 1998. [Abs] Bagrov, A.Y., Fedorova, O.V., Dmitrieva, R.I., Howald, W.N., Hunter, A.P., Kuznetsova, E.A., Shpen, V.M.: Characterization of a urinary bufodienolide Na+,K+-ATPase inhibitor in patients after acute myocardial infarction. Hypertension 31: 1097-103, 1998. [Abs] Bai, G., Norton, D.D., Prenger, M.S., Kusiak, J.W.: Single-stranded DNA-binding proteins and neuron-restrictive silencer factor participate in cell-specific transcriptional control of the NMDAR1 gene. J Biol Chem 273: 1086-91, 1998. [Abs] Balagopalakrishna, C., Abugo, O.O., Horsky, J., Manoharan, P.T., Nagababu, E., Rifkind, J.M.: Superoxide produced in the heme pocket of the beta-chain of hemoglobin reacts with the beta-93 cysteine to produce a thiyl radical. Biochemistry 37: 13194-202, 1998. [Abs] Balajee, A.S., May, A., Bohr, V.A.: Fine structural analysis of DNA repair in mammalian cells. Mutat Res 404: 3-11, 1998. [Abs] Baskar, P.V., Collins, G.D., Dorsey-Cooper, B.A., Pyle, R.S., Nagel, J.E., Dwyer, D., Dunston, G., Johnson, C.E., Kendig, N., Israel, E., Nalin, D.R., Adler, W.H.: Serum antibodies to HIV-1 are produced post-measles virus infection: evidence for cross-reactivity with HLA. Clin Exp Immunol 111: 251-6, 1998. [Abs] Basso, A., Piantanelli, L., Rossolini, G., Roth, G.S.: Reduced DNA synthesis in primary cultures of hepatocytes from old mice is restored by thymus grafts. J Gerontol A Biol Sci Med Sci 53: B111-6, 1998. [Abs] Beamer, B.A., Yen, C.J., Andersen, R.E., Muller, D., Elahi, D., Cheskin, L.J., Andres, R., Roth, J., Shuldiner, A.R.: Association of the Pro12Ala variant in the peroxisome proliferator- activated receptor-gamma2 gene with obesity in two Caucasian populations. Diabetes 47: 1806-8, 1998. [Abs] Beason-Held, L.L., Purpura, K.P., Krasuski, J.S., Maisog, J.M., Daly, E.M., Mangot, D.J., Desmond, R.E., Optican, L.M., Schapiro, M.B., VanMeter, J.W.: Cortical regions involved in visual texture perception: a fMRI study. Brain Res Cogn Brain Res 7: 111-8, 1998. [Abs] Beason-Held, L.L., Purpura, K.P., Van Meter, J.W., Azari, N.P., Mangot, D.J., Optican, L.M., Mentis, M.J., Alexander, G.E., Grady, C.L., Horwitz, B., Rapoport, S.I., Schapiro, M.B.: PET reveals occipitotemporal pathway activation during elementary form perception in humans. Vis Neurosci 15: 503-10, 1998. [Abs] Biddison, W.E., Cruikshank, W.W., Center, D.M., Pelfrey, C.M., Taub, D.D., Turner, R.V.: CD8+ myelin peptide-specific T cells can chemoattract CD4+ myelin peptide-specific T cells: importance of IFN-inducible protein 10 J Immunol 160: 444-8, 1998. [Abs] Bogdanov, K.Y., Spurgeon, H.A., Vinogradova, T.M., Lakatta, E.G.: Modulation of the transient outward current in adult rat ventricular myocytes by polyunsaturated fatty acids. Am J Physiol 274: H571-9, 1998. [Abs] Bohr, V.A., Dianov, G., Balajee, A., May, A., Orren, D.K.: DNA repair and transcription in human premature aging disorders. J Investig Dermatol Symp Proc 3: 11-3, 1998. [Abs] Bradham, D.M., Horton, W.E., Jr.: In vivo cartilage formation from growth factor modulated articular chondrocytes. Clin Orthop 239-249, 1998. [Abs] Brock, D.B., Foley, D.J.: Demography and epidemiology of dying in the U.S. with emphasis on deaths of older persons. Hosp J 13: 49-60, 1998. [Abs] Carmona, G.N., Schindler, C.W., Shoaib, M., Jufer, R., Cone, E.J., Goldberg, S.R., Greig, N.H., Yu, Q.S., Gorelick, D.A.: Attenuation of cocaine-induced locomotor activity by butyrylcholinesterase. Exp Clin Psychopharmacol 6: 274-9, 1998. [Abs] Chan, T.A., Morin, P.J., Vogelstein, B., Kinzler, K.W.: Mechanisms underlying nonsteroidal antiinflammatory drug-mediated apoptosis. Proc Natl Acad Sci USA 95: 681-6, 1998. [Abs] Chandrasekaran, K., Hatanpaa, K., Brady, D.R., Stoll, J., Rapoport, S.I.: Downregulation of oxidative phosphorylation in Alzheimer disease: loss of cytochrome oxidase subunit mRNA in the hippocampus and entorhinal cortex. Brain Res 796: 13-9, 1998. [Abs] Chandrasekaran, K., Hatanpaa, K., Liu, L-I., Rapoport, S.I.: Moleculalr mechanisms of impaired mitochondrial gene expression in Alxheimer's disease. In: Gonzalex-Lima (Ed.) Cytochrom Oxidase in Neuronal Metabolism, Plenum Press, New York, 203-216, 1998. Chang, M.C., Jones, C.R.: Chronic lithium treatment decreases brain phospholipase A2 activity. Neurochem Res 23: 887-92, 1998. [Abs] Chase, D., Feng, Y., Hanshew, B., Winkles, J.A., Longo, D.L., Ferris, D.K.: Expression and phosphorylation of fibroblast-growth-factor-inducible kinase (Fnk) during cell-cycle progression. Biochem J 333: 655-660, 1998. [Abs] Chen, C.H., Ting, C.T., Lin, S.J., Hsu, T.L., Ho, S.J., Chou, P., Chang, M.S., O'Connor, F., Spurgeon, H., Lakatta, E., Yin, F.C.: Which arterial and cardiac parameters best predict left ventricular mass?. Circulation 98: 422-8, 1998. [Abs] Chen, E., Hrdlickova, R., Nehyba, J., Longo, D.L., Bose, H.R., Jr., Li, C.C.H.: Degradation of proto-oncoprotein c-Rel by the ubiquitin-proteasome pathway. J Biol Chem 273: 35201-7, 1998. [Abs] Chen, W., Martindale, J.L., Holbrook, N.J., Liu, Y.: Tumor promoter arsenite activates extracellular signal-regulated kinase through a signaling pathway mediated by epidermal growth factor receptor and Shc. Mol Cell Biol 18: 5178-88, 1998. [Abs] Cheng, L., Mantile, G., Pauly, R., Nater, C., Felici, A., Monticone, R., Bilato, C., Gluzband, Y.A., Crow, M.T., Stetler-Stevenson, W., Capogrossi, M.C.: Adenovirus-mediated gene transfer of the human tissue inhibitor of metalloproteinase-2 blocks vascular smooth muscle cell invasiveness in vitro and modulates neointimal development in vivo. Circulation 98: 2195-201, 1998. [Abs] Conwit, R.A., Tracy, B., Cowl, A., McHugh, M., Stashuk, D., Brown, W.F., Metter, E.J.: Firing rate analysis using decompostion-enhanced spike triggered averaging in the quadriceps femoris. Muscle Nerve 21: 1338-40, 1998. [Abs] Costa, P.T. and McCrae, R.R.: Six approaches to the explication of facet-level traits: Examples from conscientiousness. Eur J Personality 12: 117-134, 1998. Costa, P.T. and McCrae, R.R.: Trait theories of personality. In: Barone, D.F., Hersen, M., and Hasselt, V.B.B. (Eds.) Advanced Personality, Plenum Press, New York, 103-121, 1998. Crow, M.T., Long, S., Guglielmi, M.B., Asai, T., Lakatta, E.G.: The role of the tumor suppressor gene p53 in cardiomyocyte apoptosis. Heart Failure and Reviews 3: 45-61, 1998. Cullinane, C., Bohr, V.A.: DNA interstrand cross-links induced by psoralen are not repaired in mammalian mitochondria. Cancer Res 58: 1400-4, 1998. [Abs] Curti, B.D., Ochoa, A.C., Powers, G.C., Kopp, W.C., Alvord, W.G., Janik, J.E., Gause, B.L., Dunn, B., Kopreski, M.S., Fenton, R., Zea, A., Dansky-Ullmann, C., Strobl, S., Harvey, L., Nelson, E., Sznol, M., Longo, D.L.: Phase I trial of anti-CD3-stimulated CD4+ T cells, infusional interleukin-2, and cyclophosphamide in patients with advanced cancer. J Clin Oncol 16: 2752-60, 1998. [Abs] DaSilva, L., Kirken, R.A., Taub, D.D., Evans, G.A., Duhe, R.J., Bailey, M.A., Farrar, W.L.: Molecular cloning of FKHRL1P2, a member of the developmentally regulated fork head domain transcription factor family. Gene 221: 135-42, 1998. [Abs] Dai, R.M., Chen, E., Longo, D.L., Gorbea, C.M., Li, C.C.: Involvement of valosin-containing protein, an ATPase Co-purified with IkappaBalpha and 26 S proteasome, in ubiquitin-proteasome-mediated degradation of IkappaBalpha. J Biol Chem 273: 3562-73, 1998. [Abs] Davatzikos, C., Resnick, S.M.: Sex differences in anatomic measures of interhemispheric connectivity: correlations with cognition in women but not men. Cereb Cortex 8: 635-40, 1998. [Abs] Denisova, N.A., Erat, S.A., Kelly, J.F., Roth, G.S.: Differential effect of aging on cholesterol modulation of carbachol- stimulated low-K(m) GTPase in striatal synaptosomes. Exp Gerontol 33: 249-65, 1998. [Abs] Dhokalia, A., Parsons, D.J., Anderson, D.E.: Resting end-tidal CO2 association with age, gender, and personality. Psychosom Med 60: 33-7, 1998. [Abs] Dianov, G., Bischoff, C., Piotrowski, J., Bohr, V.A.: Repair pathways for processing of 8-oxoguanine in DNA by mammalian cell extracts. J Biol Chem 273: 33811-6, 1998. [Abs] Dixon, P.H., Christie, P.T., Wooding, C., Trump, D., Grieff, M., Holm, I., Gertner, J. M., Schmidtke, J., Shah, B., Shaw, N., Smith, C., Tau, C., Schlessinger, D., Whyte, M.P., and Thakker, R.V.: Mutational analysis of PHEX gene in X-linked hypophosphatemia. J Clin Endocrinol Metab 83: 3615-23, 1998. [Abs] Doris, P.A., Bagrov, A.Y.: Endogenous sodium pump inhibitors and blood pressure regulations: An update on recent progress. Proceedings of Society Experimental Biology and Medicine 218: 156-167, 1998. Fauci, A.S., Longo, D.L.: The human retroviruses. In: Fauci, A.S., Braunwald, E., Isselbacher, K.J., Wilson, J.D., Martin, J.B., Kasper, D.L., Hauser, S.L., and Longo, D.L. (Eds.) Harrison's Principles of Internal Medicine, McGraw-Hill, New York, 1105-1111, 1998. Fedorova, O.V., Anderson, D.E., Bagrov, A.Y.: Plasma marinobufagenin-like and ouabain-like immunoreactivity in adrenocorticotropin-treated rats. Am J Hypertens 11: 796-802, 1998. [Abs] Fedorova, O.V., Doris, P.A., Bagrov, A.Y.: Endogenous marinobufagenin-like factor in acute plasma volume expansion. Clin Exp Hypertens 20: 581-91, 1998. [Abs] Feng, L., Precht, P., Balakir, R., Horton, W.E., Jr.: Evidence of a direct role for Bcl-2 in the regulation of articular chondrocyte apoptosis under the conditions of serum withdrawal and retinoic acid treatment. J Cell Biochem 71: 302-9, 1998. [Abs] Fenton, R.G., Turcovski-Corrales, S.M., Taub, D.D.: Induction of melanoma antigen-specific cytotoxic T lymphocytes in vitro by stimulation with B7-expressing human melanoma cell lines. J Immunother 21: 95-108, 1998. [Abs] Fenton, R.G., Longo, D.L.: Cell biology of cancer. In: Fauci, A.S., Braunwald, E., Isselbacher, K.J., Wilson, J.D., Martin, J.B., Kasper, D.L., Hauser, S.L., and Longo, D.L. (Eds.) Harrison's Principles of Internal Medicine, McGraw-Hill, New York, 505-512, 1998. Fleg, J.L., Kitzman, D.W., Aronow, W.S., Rich, M.W., Gardin, J.M., Slone, S.A.: Physician management of patients with heart failure and normal versus decreased left ventricular systolic function. Council on Geriatric Cardiology. Am J Cardiol 81: 506-9, 1998. [Abs] Fozard, J.L.: Contributions of longitudinal studies to epidemiology and disease prevention: An overview. Aust J of Ageing 17: 22-24, 1998. Galdzicki, Z., Coan, E.J., Rapoport, S.I., Stoll, J.: Increased expression of voltage-activated calcium channels in cultured hippocampal neurons from mouse trisomy 16, a model for down syndrome. Brain Res Mol Brain Res 56: 200-6, 1998. [Abs] Gambassi, G., Spurgeon, H.A., Ziman, B.D., Lakatta, E.G., Capogrossi, M.C.: Opposing effects of alpha 1-adrenergic receptor subtypes on Ca2+ and pH homeostasis in rat cardiac myocytes. Am J Physiol 274: H1152-62, 1998. [Abs] Gause, B.L., Sharfman, W.H., Janik, J.E., Curti, B.D., Steis, R.G., Urba, W.J., Smith, J.W., 2nd, Alvord, W.G., Longo, D.L.: A phase II study of carboplatin, cisplatin, interferon-alpha, and tamoxifen for patients with metastatic melanoma. Cancer Invest 16: 374-80, 1998. [Abs] Goldszal, A.F., Davatzikos, C., Pham, D.L., Yan, M.X., Bryan, R.N., Resnick, S.M.: An image-processing system for qualitative and quantitative volumetric analysis of brain images. J Comput Assist Tomogr 22: 827-37, 1998. [Abs] Goldszal, A.F., Davatzikos, C., Pham, D.L., Bryan, R.N., Resnick, S.M.: Volumeric analysis of brain images in sterotaxic space. Neuroimage 7: S726, 1998. Golski, S., Zonderman, A.B., Malamut, B.L., Resnick, S.M.: Verbal and figural recognition memory: task development and age associations. Exp Aging Res 24: 359-85, 1998. [Abs] Gonick, H.C., Ding, Y., Vaziri, N.D., Bagrov, A.Y., Fedorova, O.V.: Simultaneous measurement of marinobufagenin, ouabain, and hypertension- associated protein in various disease states. Clin Exp Hypertens 20: 617-27, 1998. [Abs] Gorospe, M., Wang, X., Holbrook, N.J.: p53-dependent elevation of p21Waf1 expression by UV light is mediated through mRNA stabilization and involves a vanadate-sensitive regulatory system. Mol Cell Biol 18: 1400-7, 1998. [Abs] Grady, C.L., McIntosh, A.R., Bookstein, F., Horwitz, B., Rapoport, S.I., Haxby, J.V.: Age-related changes in regional cerebral blood flow during working memory for faces. Neuroimage 8: 409-25, 1998. [Abs] Griffith, C.E., Zhang, W., Wange, R.L.: ZAP-70-dependent and -independent activation of Erk in Jurkat T cells. Differences in signaling induced by H2o2 and Cd3 cross-linking. J Biol Chem 273: 10771-6, 1998. [Abs] Griffiths, E.J., Ocampo, C.J., Savage, J.S., Rutter, G.A., Hansford, R.G., Stern, M. D., Silverman, H.S.: Mitochondrial calcium transporting pathways during hypoxia and reoxygenation in single rat cardiomyocytes. Cardiovasc Res 39: 423-33, 1998. [Abs] Grimm, M.C., Ben-Baruch, A., Taub, D.D., Howard, O.M., Resau, J.H., Wang, J.M., Ali, H., Richardson, R., Snyderman, R., Oppenheim, J.J.: Opiates transdeactivate chemokine receptors: delta and mu opiate receptor-mediated heterologous desensitization. J Exp Med 188: 317-25, 1998. [Abs] Grimm, M.C., Ben-Baruch, A., Taub, D.D., Howard, O.M., Wang, J.M., Oppenheim, J.J.: Opiate inhibition of chemokine-induced chemotaxis. Ann N Y Acad Sci 840: 9-20, 1998. [Abs] Guyton, K.Z., Gorospe, M., Wang, X., Mock, Y.D., Kokkonen, G.C., Liu, Y., Roth, G.S., Holbrook, N.J.: Age-related changes in activation of mitogen-activated protein kinase cascades by oxidative stress. J Investig Dermatol Symp Proc 3: 23-7, 1998. [Abs] Hagberg, J.M., Goldberg, A.P., Lakatta, L., O'Connor, F.C., Becker, L.C., Lakatta, E.G., Fleg, J.L.: Expanded blood volumes contribute to the increased cardiovascular performance of endurance-trained older men. J Appl Physiol 85: 484-9, 1998. [Abs] Hampel, H., Teipel, S.J., Alexander, G.E., Horwitz, B., Teichberg, D., Schapiro, M.B., Rapoport, S.I.: Corpus callosum atrophy is a possible indicator of region- and cell type-specific neuronal degeneration in Alzheimer disease: a magnetic resonance imaging analysis. Arch Neurol 55: 193-8, 1998. [Abs] Hansford, R. G., Zorov, D.: Role of mitochondrial calcium transport in the control of substrate oxidation. Mol Cell Biochem 184: 359-69, 1998. [Abs] Harik-Khan, R.I., Wise, R.A., Fozard, J.L.: Determinants of maximal inspiratory pressure. The Baltimore Longitudinal Study of Aging. Am J Respir Crit Care Med 158: 1459-64, 1998. [Abs] Harris, T.B., Langlois, J.A., Kiel, D.P., Hannan, M.T., Roubenoff, R.: Re: "Epidemiology of insulin-like growth factor-I in elderly men and women. The Rancho Bernardo Study". Am J Epidemiol 147: 1093-4, 1998. [Abs] Hatanpaa, K., Chandrasekaran, K., Brady, D.R., Rapoport, S.I.: No association between Alzheimer plaques and decreased levels of cytochrome oxidase subunit mRNA, a marker of neuronal energy metabolism. Brain Res Mol Brain Res 59: 13-21, 1998. [Abs] Hathcock, K.S., Weng, N.P., Merica, R., Jenkins, M.K., Hodes, R.: Antigen-dependent regulation of telomerase activity in murine T cells. J Immunol 160: 5702-6, 1998. [Abs] Hattori, A., Luo, Y., Umegaki, H., Munoz, J., Roth, G.S.: Intrastriatal injection of dopamine results in DNA damage and apoptosis in rats. Neuroreport 9: 2569-72, 1998. [Abs] Hayakawa, T., Chang, M.C.J., Bell, J.M., Seeman, R., Rapoport, S.I., Appel, N.M.: Fatty acid incorporation depicts brain activity in a rat model of Parkinson's disease. Brain Res 807: 177-81, 1998. [Abs] He, T.C., Sparks, A.B., Rago, C., Hermeking, H., Zawel, L., da Costa, L.T., Morin, P. J., Vogelstein, B., Kinzler, K.W.: Identification of c-MYC as a target of the APC pathway. Science 281: 1509-12, 1998. [Abs] Henry, P.H. and Longo, D.L.: Enlargement of lymph nodes and spleen. In: Fauci, A.S., Braunwald, E., Isselbacher, K.J., Wilson, J.D., Martin, J.B., Kasper, D.L., Hauser, S.L., and Longo, D.L. (Eds.) Harrison's Principles of Internal Medicine, McGraw-Hill, New York, 345-351, 1998. Hesselgesser, J., Ng, H.P., Liang, M., Zheng, W., May, K., Bauman, J.G., Monahan, S., Islam, I., Wei, G.P., Ghannam, A., Taub, D.D., Rosser, M., Snider, R.M., Morrissey, M.M., Perez, H.D., Horuk, R.: Identification and characterization of small molecule functional antagonists of the CCR1 chemokine receptor. J Biol Chem 273: 15687-92, 1998. [Abs] Hirsch, R., Lethbridge-Cejku, M., Hanson, R., Scott, W.W., Jr., Reichle, R., Plato, C.C., Tobin, J.D., Hochberg, M.C.: Familial aggregation of osteoarthritis: data from the Baltimore Longitudinal Study on Aging. Arthritis Rheum 41: 1227-32, 1998. [Abs] Hogaboam, C., Kunkel, S.L., Strieter, R.M., Taub, D.D., Lincoln, P., Standiford, T.J., Lukacs, N.W.: Novel role of transmembrane SCF for mast cell activation and eotaxin production in mast cell-fibroblast interactions. J Immunol 160: 6166-71, 1998. [Abs] Horton, W.E., Jr., Feng, L., Adams, C.: Chondrocyte apoptosis in development, aging and disease. Matrix Biol 17: 107-15, 1998. [Abs] Horton, W.E., Jr., Udo, I., Precht, P., Balakir, R., Hasty, K.: Cytokine inducible matrix metalloproteinase expression in immortalized rat chondrocytes is independent of nitric oxide stimulation. In Vitro Cell Dev Biol Anim 34: 378-84, 1998. [Abs] Horwitz, B., Rumsey, J.M., Donohue, B.C.: Functional connectivity of the angular gyrus in normal reading and dyslexia. Proc Natl Acad Sci USA 95: 8939-44, 1998. [Abs] Hu, Q., Corda, S., Zweier, J.L., Capogrossi, M.C., Ziegelstein, R.C.: Hydrogen peroxide induces intracellular calcium oscillations in human aortic endothelial cells. Circulation 97: 268-75, 1998. [Abs] Huber, R., Schlessinger, D., Pilia, G.: Multiple Sp1 sites efficiently drive transcription of the TATA-less promoter of the human glypican 3 (GPC3) gene. Gene 214: 35-44, 1998. [Abs] Hudson, E.K., Tsuchiya, N., Hansford, R.G.: Age-associated changes in mitochondrial mRNA expression and translation in the Wistar rat heart. Mech Ageing Dev 103: 179-93, 1998. [Abs] Ibanez, V., Pietrini, P., Alexander, G.E., Furey, M.L., Teichberg, D., Rajapakse, J.C., Rapoport, S.I., Schapiro, M.B., Horwitz, B.: Regional glucose metabolic abnormalities are not the result of atrophy in Alzheimer's disease. Neurology 50: 1585-93, 1998. [Abs] Ihde, D.C. and Longo, D.L.: Presentations of the patient with cancer: Solid tumors in adults. In: Fauci, A.S., Braunwald, E., Isselbacher, K.J., Wilson, J.D., Martin, J.B., Kasper, D.L., Hauser, S.L., and Longo, D.L. (Eds.) Harrison's Principles of Internal Medicine, McGraw-Hill, New York, 360-362, 1998. Ingram, D.K., Spangler, E.L., Kametani, H., Meyer, R.C., London, E.D.: Intracerebroventricular injection of N omega-nitro-L-arginine in rats impairs learning in a 14-unit T-maze. Eur J Pharmacol 341: 11-6, 1998. [Abs] Ingram, D.K., Spangler, E.L., Meyer, R.C., London, E.D.: Learning in a 14-unit T-maze is impaired in rats following systemic treatment with N omega-nitro-L-arginine. Eur J Pharmacol 341: 1-9, 1998. [Abs] Jaiswal, M., Lipinski, L.J., Bohr, V.A., Mazur, S.J.: Efficient in vitro repair of 7-hydro-8-oxodeoxyguanosine by human cell extracts: involvement of multiple pathways. Nucleic Acids Res 26: 2184-91, 1998. [Abs] Jang, K.L., McCrae, R.R., Angleitner, A., Riemann, R., Livesley, W.J.: Heritability of facet-level traits in a cross-cultural twin sample: support for a hierarchical model of personality. J Pers Soc Psychol 74: 1556-65, 1998. [Abs] Jaradat, S.A., Ko, M.S., Grossman, L.I.: Tissue-specific expression and mapping of the Cox7ah gene in mouse. Genomics 49: 363-70, 1998. [Abs] Jefferson, T. Jr., Herbst, J.H., McCrae, R.R.: Associations between birth order and personality traits: Evidence from self-reports and observer ratings. J Res Pers 32: 498-509, 1998. Jenkins, G.M., Crow, M.T., Bilato, C., Gluzband, Y., Ryu, W.S., Li, Z., Stetler-Stevenson, W., Nater, C., Froehlich, J.P., Lakatta, E.G., Cheng, L.: Increased expression of membrane-type matrix metalloproteinase and preferential localization of matrix metalloproteinase-2 to the neointima of balloon-injured rat carotid arteries. Circulation 97: 82-90, 1998. [Abs] Katzel, L.I., Fleg, J.L., Busby-Whitehead, M.J., Sorkin, J.D., Becker, L.C., Lakatta, E.G., Goldberg, A.P.: Exercise-induced silent myocardial ischemia in master athletes. Am J Cardiol 81: 261-5, 1998. [Abs] Kitano, S., Bohr, V.A., Reed, T.D., Haggerty, C.M., May, A., Roth, G.S.: Effect of aging on EGF-stimulated replication of specific genes in rat hepatocytes. J Cell Physiol 176: 32-9, 1998. [Abs] Kitano, S., Fawcett, T.W., Yo, Y., Roth, G.S.: Molecular mechanisms of impaired stimulation of DNA synthesis in cultured hepatocytes of aged rats. Am J Physiol 275: C146-54, 1998. [Abs] Ko, M.S.H., Threat, T.A., Wang, X., Horton, J.H., Cui, Y., Pryor, E., Paris, J., Wells-Smith, J., Kitchen, J.R., Rowe, L.B., Eppig, J., Satoh, T., Brant, L., Fujiwara, H., Yotsumoto, S., Nakashima, H.: Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet 7: 1967-78, 1998. [Abs] Koban, M.U., Moorman, A.F., Holtz, J., Yacoub, M.H., Boheler, K.R.: Expressional analysis of the cardiac Na-Ca exchanger in rat development and senescence. Cardiovasc Res 37: 405-23, 1998. [Abs] Krainc, D., Bai, G., Okamoto, S., Carles, M., Kusiak, J.W., Brent, R.N., Lipton, S.A.: Synergistic activation of the N-methyl-D-aspartate receptor subunit 1 promoter by myocyte enhancer factor 2C and Sp1. J Biol Chem 273: 26218-24, 1998. [Abs] Krasuski, J.S., Alexander, G.E., Horwitz, B., Daly, E.M., Murphy, D.G., Rapoport, S.I., Schapiro, M.B.: Volumes of medial temporal lobe structures in patients with Alzheimer's disease and mild cognitive impairment (and in healthy controls). Biol Psychiatry 43: 60-8, 1998. [Abs] Kwon, T.K., Nordin, A.A.: Identification of cdk2 binding sites on the p27Kip1 cyclin-dependent kinase inhibitor. Oncogene 16: 755-62, 1998. [Abs] Kwon, T.K., Buchholz, M.A., Jun, D.Y., Kim, Y.H., Nordin, A.A.: The differential catalytic activity of alternatively spliced cdk2 alpha and cdk2 beta in the G1/S transition and early S phase. Exp Cell Res 238: 128-35, 1998. [Abs] Lakatta, E.G.: Aging and cardiovascular structure and function in healthy sedentary humans. Aging (Milano) 10: 162-4, 1998. [Abs] Langlois, J.A., Rosen, C.J., Visser, M., Hannan, M.T., Harris, T., Wilson, P.W., Kiel, D.P.: Association between insulin-like growth factor I and bone mineral density in older women and men: the Framingham Heart Study. J Clin Endocrinol Metab 83: 4257-62, 1998. [Abs] Langlois, J.A., Visser, M., Davidovic, L.S., Maggi, S., Li, G., Harris, T.B.: Hip fracture risk in older white men is associated with change in body weight from age 50 years to old age. Arch Intern Med 158: 990-6, 1998. [Abs] Leary, S.C., Battersby, B.J., Hansford, R.G., Moyes, C.D.: Interactions between bioenergetics and mitochondrial biogenesis. Biochim Biophys Acta 1365: 522-30, 1998. [Abs] Lee-Kwon, W., Park, D., Bernier, M.: Involvement of the Ras/extracellular signal-regulated kinase signalling pathway in the regulation of ERCC-1 mRNA levels by insulin. Biochem J 331: 591-7, 1998. [Abs] Lee-Kwon, W., Park, D., Bernier, M.: Nucleotide excision repair is not required for the antiapoptotic function of insulin-like growth factor 1. Exp Cell Res 241: 458-66, 1998. [Abs] Lee-Kwon, W., Park, D., Baskar, P.V., Kole, S., Bernier, M.: Antiapoptotic signaling by the insulin receptor in Chinese hamster ovary cells. Biochemistry 37: 15747-57, 1998. [Abs] Leveille, S.G., Guralnik, J.M., Ferrucci, L., Corti, M.C., Kasper, J., Fried, L.P.: Black/white differences in the relationship between MMSE scores and disability: the Women's Health and Aging Study. J Gerontol B Psychol Sci Soc Sci 53: 201-8, 1998. [Abs] Leveille, S.G., Guralnik, J.M., Ferrucci, L., Hirsch, R., Simonsick, E., Hochberg, M.C.: Foot pain and disability in older women. Am J Epidemiol 148: 657-65, 1998. [Abs] Leveille, S.G., Wagner, E.H., Davis, C., Grothaus, L., Wallace, J., LoGerfo, M., Kent, D.: Preventing disability and managing chronic illness in frail older adults: a randomized trial of a community-based partnership with primary care. J Am Geriatr Soc 46: 1191-8, 1998. [Abs] Lin, H., Black, L.W.: DNA requirements in vivo for phage T4 packaging. Virology 242: 118-27, 1998. [Abs] Lipinski, L.J., Ross, H.L., Zajc, B., Sayer, J.M., Jerina, D.M., Dipple, A.: Effect of single benzo[a]pyrene diol epoxide-deoxyguanosine adducts on the action of DNA polymerases in vitro. Int J Oncol 13: 269-73, 1998. [Abs] Little, R., Wittes, R.E., Longo, D.L., Wilson, W. H.: Vinblastine for recurrent Hodgkin's disease following autologous bone marrow transplant. J Clin Oncol 16: 584-8, 1998. [Abs] Liu, Y., Gorospe, M., Kokkonen, G.C., Boluyt, M.O., Younes, A., Mock, Y.D., Wang, X., Roth, G.S., Holbrook, N.J.: Impairments in both p70 S6 kinase and extracellular signal-regulated kinase signaling pathways contribute to the decline in proliferative capacity of aged hepatocytes. Exp Cell Res 240: 40-8, 1998. [Abs] Liu, Y., Gorospe, M., Holbrook, N.J., Anderson, C.: Post-translational mechanisms leading to mammalian gene activation in response to genotoxic stress. In: Hoekstra, M.F. and Nickoloff, J.A. (Eds.) DNA Damage and Repair, Humana Press, 263-298, 1998. Liu, Y., Holbrook, N.J., Kokkonen, G.C., and Roth, G.S.: Intracellular signal transduction and receptor activity in stimulated hepatocyte DNA synthesis. In: Yu, B.P. (Ed.) Methods in Aging Research, CRC Press, 515-532, 1998. Long, J.M., Kalehua, A.N., Muth, N.J., Hengemihle, J.M., Jucker, M., Calhoun, M.E., Ingram, D.K., Mouton, P.R.: Stereological estimation of total microglia number in mouse hippocampus. J Neurosci Methods 84: 101-8, 1998. [Abs] Long, X., Crow, M.T., Sollott, S.J., O'Neill, L., Menees, D.S., de Lourdes Hipolito, M., Boluyt, M.O., Asai, T., Lakatta, E.G.: Enhanced expression of p53 and apoptosis induced by blockade of the vacuolar proton ATPase in cardiomyocytes. J Clin Invest 101: 1453-61, 1998. [Abs] Longo, D.L.: Interferon toxicity worse in retrospect; impact on Q-TWiST? Quality- Adjusted Time Without Symptoms or Toxicity. J Clin Oncol 16: 3716; discussio, 1998. [Abs] Longo, D.L.: Solving the puzzle of follicular lymphoma. Cancer J Sci Am 4 Suppl 2: S1-4, 1998. [Abs] Longo, D.L.: Approach to the patient with cancer. In: Fauci, A.S., Braunwald, E., Isselbacher, K.J., Wilson, J.D., Martin, J.B., Kasper, D.L., Hauser, S.L., and Longo, D.L. (Eds.) Harrison's Principles of Internal Medicine, McGraw-Hill, New York, 493-499, 1998. Longo, D.L.: Plasma cell disorders. In: Fauci, A.S., Braunwald, E., Isselbacher, K.J., Wilson, J.D., Martin, J.B., Kasper, D.L., Hauser, S.L., and Longo, D.L. (Eds.) Harrison's Principles of Internal Medicine, McGraw-Hill, New York, 712-718, 1998. Losonczy, K.G., White, L.R., Brock, D.B.: Prevalence and correlates of dementia: survey of the last days of life. Public Health Rep 113: 273-80, 1998. [Abs] Luo, Y., Kokkonen, G.C., Wang, X., Neve, K.A., Roth, G.S.: D2 dopamine receptors stimulate mitogenesis through pertussis toxin- sensitive G proteins and Ras-involved ERK and SAP/JNK pathways in rat C6-D2L glioma cells. J Neurochem 71: 980-90, 1998. [Abs] Luo, Y., Umegaki, H., Wang, X., Abe, R., Roth, G.S.: Dopamine induces apoptosis through an oxidation-involved SAPK/JNK activation pathway. J Biol Chem 273: 3756-64, 1998. [Abs] Madio, D.P., van Gelderen, P., DesPres, D., Olson, A.W., de Zwart, J.A., Fawcett, T.W., Holbrook, N.J., Mandel, M., Moonen, C.T.: On the feasibility of MRI-guided focused ultrasound for local induction of gene expression. J Magn Reson Imaging 8: 101-4, 1998. [Abs] Markowska, A.L., Spangler, E.L., Ingram, D.K.: Behavioral assessment of the senescence-accelerated mouse (SAM P8 and R1). Physiol Behav 64: 15-26, 1998. [Abs] Matthews, G., Saklofske, D.H., Costa, P.T. Jr., Deary, , I.J., Zeidner, M.: Dimensional models of personality: A framework for systematic clinical assessment. Eur J Psychological Assessment 14: 36-49, 1998. Mazzarella, R. and Schlessinger, D.: Pathological consequences of sequence duplications in the human genome. Genome Res 8: 1007-21, 1998. [Abs] Mazzarella, R., Pengue, G., Jones, J., Jones, C., Schlessinger, D.: Cloning and expression of an immunoglobulin superfamily gene (IGSF1) in Xq25. Genomics 48: 157-62, 1998. [Abs] McCrae, R.R., Stone, S.V., Fagan, P.J., Costa, P.T., Jr.: Identifying causes of disagreement between self-reports and spouse ratings of personality. J Pers 66: 285-313, 1998. [Abs] McCrae, R.R., Yik, M.S., Trapnell, P.D., Bond, M.H., Paulhus, D.L.: Interpreting personality profiles across cultures: bilingual, acculturation, and peer rating studies of Chinese undergraduates. J Pers Soc Psychol 74: 1041-55, 1998. [Abs] McCrae, R.R.: An empirically based alternative framework. Psychological Inquiry 9: 158-160, 1998. McCrae, R.R., Costa, P.T. Jr., Del Pilar, G.H., Rolland, J.P., Parker, W.D.: Cross-cultural assessment of the five-factor model: The revised NEO personality inventory. J Cross-Cultural Psychol 29: 171-188, 1998. Mentis, M.J., Alexander, G.E., Krasuski, J., Pietrini, P., Furey, M.L., Schapiro, M.B., Rapoport, S.I.: Increasing required neural response to expose abnormal brain function in mild versus moderate or severe Alzheimer's disease: PET study using parametric visual stimulation. Am J Psychiatry 155: 785-94, 1998. [Abs] Meyer, R.C., Knox, J., Purwin, D.A., Spangler, E.L., Ingram, D.K.: Combined stimulation of the glycine and polyamine sites of the NMDA receptor attenuates NMDA blockade-induced learning deficits of rats in a 14-unit T-maze. Psychopharmacology (Berl) 135: 290-5, 1998. [Abs] Meyer, R.C., Spangler, E.L., Patel, N., London, E.D., Ingram, D.K.: Impaired learning in rats in a 14-unit T-maze by 7-nitroindazole, a neuronal nitric oxide synthase inhibitor, is attenuated by the nitric oxide donor, molsidomine. Eur J Pharmacol 341: 17-22, 1998. [Abs] Mikovits, J.A., Taub, D.D., Turcovski-Corrales, S.M., Ruscetti, F.W.: Similar levels of human immunodeficiency virus type 1 replication in human TH1 and TH2 clones. J Virol 72: 5231-8, 1998. [Abs] Mikovits, J.A., Young, H.A., Vertino, P., Issa, J.P., Pitha, P.M., Turcoski-Corrales, S., Taub, D.D., Petrow, C.L., Baylin, S.B., Ruscetti, F.W.: Infection with human immunodeficiency virus type 1 upregulates DNA methyltransferase, resulting in de novo methylation of the gamma interferon (IFN-gamma) promoter and subsequent downregulation of IFN- gamma production. Mol Cell Biol 18: 5166-77, 1998. [Abs] Montonen, O., Ezer, S., Saarialho-Kere, U.K., Herva, R., Karjalainen-Lindsberg, M.L., Kaitila, I., Schlessinger, D., Srivastava, A.K., Thesleff, I., Kere, J.: The gene defective in anhidrotic ectodermal dysplasia is expressed in the developing epithelium, neuroectoderm, thymus, and bone. J Histochem Cytochem 46: 281-9, 1998. [Abs] Mumm, S., Jermak, C., Waeltz, P., Schmatz, M., Terrell, J., McCauley, B., Shoemaker, M., Srivastava, A., Kere, J., Nagaraja, R.: 22-Mb integrated physical and genetic map based on YAC/STS content spanning the interval DXS1125-DXS95 in human Xq12-q21.31. Gene 208: 147-56, 1998. [Abs] Murphy, W.J., Welniak, L.A., Taub, D.D., Wiltrout, R.H., Taylor, P.A., Vallera, D.A., Kopf, M., Young, H., Longo, D.L., Blazar, B.R.: Differential effects of the absence of interferon-gamma and IL-4 in acute graft-versus-host disease after allogeneic bone marrow transplantation in mice. J Clin Invest 102: 1742-8, 1998. [Abs] Nagababu, E., Rifkind, J.M.: Formation of fluorescent heme degradation products during the oxidation of hemoglobin by hydrogen peroxide. Biochem Biophys Res Commun 247: 592-6, 1998. [Abs] Nagai, Y., Kemper, M.K., Earley, C.J., Metter, E.J.: Blood-flow velocities and their relationships in carotid and middle cerebral arteries. Ultrasound Med Biol 24: 1131-6, 1998. [Abs] Nagai, Y., Metter, E.J., Earley, C.J., Kemper, M.K., Becker, L.C., Lakatta, E.G., Fleg, J.L.: Increased carotid artery intimal-medial thickness in asymptomatic older subjects with exercise-induced myocardial ischemia. Circulation 98: 1504-9, 1998. [Abs] Nagaraja, R., Jermak, C., Trusgnich, M., Yoon, J., MacMillan, S., McCauley, M.B., Brownstein, B., Schlessinger, D.: YAC/STS map of 15Mb of Xp21.3-p11.3, at 100kb resolution, with refined comparisons of genetic distances and DMD structure. Gene 215: 259-67, 1998. [Abs] Nagaraja, R., MacMillan, S., Jones, C., Masisi, M., Pengue, G., Porta, G., Miao, S., Casamassimi, A., D'Urso, M., Brownstein, B., Schlessinger, D.: Integrated YAC/STS physical and genetic map of 22.5 Mb of human Xq24- q26 at 56-kb inter-STS resolution. Genomics 52: 247-66, 1998. [Abs] Nakamura, E., Lane, M.A., Roth, G.S., Ingram, D.K.: A strategy for identifying biomarkers of aging: further evaluation of hematology and blood chemistry data from a calorie restriction study in rhesus monkeys. Exp Gerontol 33: 421-43, 1998. [Abs] Nguyen, B.Y., Clerici, M., Venzon, D.J., Bauza, S., Murphy, W.J., Longo, D.L., Baseler, M., Gesundheit, N., Broder, S., Shearer, G., Yarchoan, R.: Pilot study of the immunologic effects of recombinant human growth hormone and recombinant insulin-like growth factor in HIV-infected patients. Aids 12: 895-904, 1998. [Abs] O'Connor, K.G., Tobin, J.D., Harman, S.M., Plato, C.C., Roy, T.A., Sherman, S.S., Blackman, M.R.: Serum levels of insulin-like growth factor-I are related to age and not to body composition in healthy women and men. J Gerontol A Biol Sci Med Sci 53: M176-82, 1998. [Abs] Parshad, R., Price, F.M., Schapiro, M.B., Sanford, K.K.: Effect of DNA repair inhibitors on the in vitro test for Alzheimer's disease. J Am Geriatr Soc 46: 1331-3, 1998. [Abs] Patel, N., Spangler, E.L., Greig, N.H., Yu, Q.S., Ingram, D.K., Meyer, R.C.: Phenserine, a novel acetylcholinesterase inhibitor, attenuates impaired learning of rats in a 14-unit T-maze induced by blockade of the N- methyl-D-aspartate receptor. Neuroreport 9: 171-6, 1998. [Abs] Pearson, J.D., S.Y., Kao., Brant, L.J., Metter, E.J., Tockman, M.S., Fozard, J.L.: Longitudinal change in forced expiratory volume in healthy, non-smoking men and women: The Baltimore Longitudinal Study of Aging. Am J Hum Biol 10: 471-481, 1998. Penninx, B.W., Guralnik, J.M., Ferrucci, L., Simonsick, E.M., Deeg, D.J., Wallace, R.B.: Depressive symptoms and physical decline in community-dwelling older persons. JAMA 279: 1720-6, 1998. [Abs] Penninx, B.W., Guralnik, J.M., Mendes de Leon, C.F., Pahor, M., Visser, M., Corti, M.C., Wallace, R.B.: Cardiovascular events and mortality in newly and chronically depressed persons > 70 years of age. Am J Cardiol 81: 988-94, 1998. [Abs] Penninx, B.W., Guralnik, J.M., Pahor, M., Ferrucci, L., Cerhan, J.R., Wallace, R.B., Havlik, R.J.: Chronically depressed mood and cancer risk in older persons. J Natl Cancer Inst 90: 1888-93, 1998. [Abs] Penninx, B.W., Guralnik, J.M., Simonsick, E.M., Kasper, J.D., Ferrucci, L., Fried, L.P.: Emotional vitality among disabled older women: the Women's Health and Aging Study. J Am Geriatr Soc 46: 807-15, 1998. [Abs] Perfetti, R., Barnett, P.S., Mathur, R., Egan, J.M.: Novel therapeutic strategies for the treatment of type 2 diabetes. Diabetes Metab Rev 14: 207-25, 1998. [Abs] Perichon, R., Bourre, J.M., Kelly, J.F., Roth, G.S.: The role of peroxisomes in aging. Cell Mol Life Sci 54: 641-52, 1998. [Abs] Perichon, R., Moser, A.B., Wallace, W.C., Cunningham, S.C., Roth, G.S., Moser, H.W.: Peroxisomal disease cell lines with cellular plasmalogen deficiency have impaired muscarinic cholinergic signal transduction activity and amyloid precursor protein secretion. Biochem Biophys Res Commun 248: 57-61, 1998. [Abs] Philbin, E.F., Garg, R., Danisa, K., Denny, M., Gosselin, G., Hassapoyannes, C., Horney, A., Johnstone, D.E., Lang, R.M., Ramanathan, K., Safford, R.E., Sarma, R.J., Weiss, R., Williford, W.O., Fleg, J.L.: The relationship between cardiothoracic ratio and left ventricular ejection fraction in congestive heart failure. Digitalis Investigation Group. Arch Intern Med 158: 501-6, 1998. [Abs] Phung, Q.H., Winter, D.B., Cranston, A., Tarone, R.E., Bohr, V.A., Fishel, R., Gearhart, P.J.: Increased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair protein. J Exp Med 187: 1745-51, 1998. [Abs] Pietrini, P., Teipel, S.J., Bartenstein, P., Rapoport, S.I., Moller, H-J., Hampel, H.: PET and the effects of aging and neurodegeneration of brain function: Basic principles. Drug News Perspect 11: 161-165, 1998. Potter, K., Fishbein, K.W., Horton, W.E., Spencer, R.G.S.: Morphometric analaysis of cartilage grown in a hollow fiber bioreactor using NMR microscopy. In: Blumer, P., Blumlich, B., Botto, R., and Fukushima, E. (Eds.) Spatially Resolved Magnetic Resonance: Methods, Materials, Medicine, Biology, Rh, Wiley-VCH Press, Weinheim, 363-371, 1998. Purdon, A.D., Rapoport, S.I.: Energy requirements for two aspects of phospholipid metabolism in mammalian brain. Biochem J 335: 313-8, 1998. [Abs] Rabin, O., Chang, M.C., Grange, E., Bell, J., Rapoport, S.I., Deutsch, J., Purdon, A.D.: Selective acceleration of arachidonic acid reincorporation into brain membrane phospholipid following transient ischemia in awake gerbil. J Neurochem 70: 325-34, 1998. [Abs] Rabin, O., Drieu, K., Grange, E., Chang, M.C., Rapoport, S.I., Purdon, A.D.: Effects of EGb 761 on fatty acid reincorporation during reperfusion following ischemia in the brain of the awake gerbil. Mol Chem Neuropathol 34: 79-101 [MEDLINE, 1998. [Abs] Rabin, O., Purdon, A.D., Krieu, K., Grange, E., Chang, M.C.J., Deutsch, J., Rapoport, S.I.: Ginkgo biloba extract (EGB 761) may reduce neuronal death following transient cerebral ischemia by accelerating reincorporation of release arachidonic acid into brain lysophospholipids. Advs in Ginkgo Biloba Ext Res 7: 110-120, 1998. Rantanen, T., Guralnik, J.M., Izmirlian, G., Williamson, J.D., Simonsick, E.M., Ferrucci, L., Fried, L.P.: Association of muscle strength with maximum walking speed in disabled older women. Am J Phys Med Rehabil 77: 299-305, 1998. [Abs] Rantanen, T., Guralnik, J.M., Leveille, S., Izmirlian, G., Hirsch, R., Simonsick, E., Ling, S., Fried, L. P.: Racial differences in muscle strength in disabled older women. J Gerontol A Biol Sci Med Sci 53: B355-61, 1998. [Abs] Rantanen, T., Masaki, K., Foley, D., Izmirlian, G., White, L., Guralnik, J.M.: Grip strength changes over 27 yr in Japanese-American men. J Appl Physiol 85: 2047-53, 1998. [Abs] Rasmusson, D.X., Zonderman, A.B., Kawas, C., Resnick, S.M.: Effects of age and dementia on the trail making test. The Clinical Neuropsychologist 12: 169-178, 1998. Raziuddin, A., Longo, D.L., Mason, L., Ortaldo, J.R., Bennett, M., Murphy, W.J.: Differential effects of the rejection of bone marrow allografts by the depletion of activating versus inhibiting Ly-49 natural killer cell subsets. J Immunol 160: 87-94, 1998. [Abs] Resnick, S.M., Maki, P.M., Golski, S., Kraut, M. A., Zonderman, A.B.: Effects of estrogen replacement therapy on PET cerebral blood flow and neuropsychological performance. Horm Behav 34: 171-82, 1998. [Abs] Riccioni, T., Cirielli, C., Wang, X., Passaniti, A., Capogrossi, M.C.: Adenovirus-mediated wild-type p53 overexpression inhibits endothelial cell differentiation in vitro and angiogenesis in vivo. Gene Ther 5: 747-54, 1998. [Abs] Ring, H.Z., Vameghi-Meyers, V., Wang, W., Crabtree, G.R., Francke, U.: Five SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin (SMARC) genes are dispersed in the human genome. Genomics 51: 140-3, 1998. [Abs] Roubenoff, R., Harris, T.B., Abad, L.W., Wilson, P.W., Dallal, G.E., Dinarello, C.A.: Monocyte cytokine production in an elderly population: effect of age and inflammation. J Gerontol A Biol Sci Med Sci 53: M20-26, 1998. [Abs] Ruscetti, F.W., Keller, J.R., Longo, D.L.: Hematopoiesis. In: Fauci, A.S., Braunwald, E., Isselbacher, K.J., Wilson, J.D., Martin, J.B., Kasper, D.L., Hauser, S.L., and Longo, D.L. (Eds.) Harrison's Principles of Internal Medicine, McGraw-Hill, New York, 634-638, 1998. Ryan, A.S., Egan, J.M., Habener, J.F., Elahi, D.: Insulinotropic hormone glucagon-like peptide-1-(7-37) appears not to augment insulin-mediated glucose uptake in young men during euglycemia. J Clin Endocrinol Metab 83: 2399-2404, 1998. [Abs] Rywik, T.M., Zink, R.C., Gittings, N.S., Khan, A.A., Wright, J.G., O'Connor, F.C., Fleg, J.L.: Independent prognostic significance of ischemic ST-segment response limited to recovery from treadmill exercise in asymptomatic subjects. Circulation 97: 2117-2122, 1998. [Abs] Sasaki, C.Y., Passaniti, A.: Identification of anti-invasive but noncytotoxic chemotherapeutic agents using the tetrazolium dye MTT to quantitate viable cells in Matrigel. Biotechniques 24: 1038-43, 1998. [Abs] Schlessinger, D., Ko, M.S.H.: Developmental genomics and its relation to aging. Genomics 52: 113-8, 1998. [Abs] Schlessinger, D., Nagaraja, R.: Impact and implications of yeast and human artificial chromosomes. Ann Med 30: 186-91, 1998. [Abs] Scortegagna, M., Galdzicki, Z., Rapoport, S.I., Hanbauer, I.: In cortical cultures of trisomy 16 mouse brain the upregulated metallothionein-I/II fails to respond to H2O2 exposure or glutamate receptor stimulation. Brain Res 787: 292-8, 1998. [Abs] Senzaki, H., Gluzband, Y.A., Pak, P.H., Crow, M.T., Janicki, J.S., Kass, D.A.: Synergistic exacerbation of diastolic stiffness from short-term tachycardia-induced cardiodepression and angiotensin II. Circ Res 82: 503-12, 1998. [Abs] Seymour, A.B., Dash-Modi, A., O'Connell, J.R., Shaffer-Gordon, M., Mah, T.S., Stefko, S.T., Nagaraja, R., Brown, J., Kimura, A.E., Ferrell, R.E., Gorin, M.B.: Linkage analysis of X-linked cone-rod dystrophy: localization to Xp11.4 and definition of a locus distinct from RP2 and RP3. Am J Hum Genet 62: 122-9, 1998. [Abs] Shah, A.M., Sollott, S.J., Lakatta, E.G.: Physio-pharmacological evaluation of myocardial performance: an integrative approach. Cardiovasc Res 39: 148-54, 1998. [Abs] Sham, J.S.K., Song, L.S., Chen, Y., Deng, L.H., Stern, M.D., Lakatta, E.G., Cheng, H.: Termination of Ca2+ release by a local inactivation of ryanodine receptors in cardiac myocytes. Proc Natl Acad Sci USA 95: 15096-15101, 1998. Shefer, V.I., Talan, M.I.: The effect of exercise training in cold on shivering and nonshivering thermogenesis in adult and aged C57BL/6J mice. Exp Gerontol 33: 467-76, 1998. [Abs] Shkarin, P., Spencer, R.G.S.: Efficient simulation of spin echo, gradient echo, fast, and ultrafast NMR imaging sequences by isochromat summation. In: Blumer, P, Blumlich, B., Botto, R., and Fukushima, E. (Eds.) Spatially Resolved Magnetic Resonance: Methods, Materials, Medicine, Biology, Rh, Wiley-VCH Press, Weinheim, 121-132, 1998. Shrager, R.I., Weiss, G.H., Spencer, R.G.: Optimal time spacings for T2 measurements: monoexponential and biexponential systems. NMR Biomed 11: 297-305, 1998. [Abs] Simonsick, E.M., Kasper, J.D., Phillips, C.L.: Physical disability and social interaction: factors associated with low social contact and home confinement in disabled older women (The Women's Health and Aging Study). J Gerontol B Psychol Sci Soc Sci 53: S209-17, 1998. [Abs] Smith, G.D., Keizer, J.E., Stern, M.D., Lederer, W.J., Cheng, H.: A simple numerical model of calcium spark formation and detection in cardiac myocytes. Biophys J 75: 15-32, 1998. [Abs] Sneed, C.D., McCrae, R.R., Funder, D.C.: Lay conceptions of the five-factor model and its indicators. Personality and Social Psychology Bulletin 24: 115-126, 1998. Song, L.S., Sham, J.S., Stern, M.D., Lakatta, E.G., Cheng, H.: Direct measurement of SR release flux by tracking 'Ca2+ spikes' in rat cardiac myocytes. J Physiol (Lond) 512: 677-91, 1998. [Abs] Sparks, A.B., Morin, P.J., Vogelstein, B., Kinzler, K.W.: Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer. Cancer Res 58: 1130-4, 1998. [Abs] Spence, S.E., Keller, J.R., Ruscetti, F.W., McCauslin, C.S., Gooya, J.M., Funakoshi, S., Longo, D.L., Murphy, W.J.: Engraftment of ex vivo expanded and cycling human cord blood hematopoietic progenitor cells in SCID mice. Exp Hematol 26: 507-14, 1998. [Abs] Spencer, R.G.: Comparing individual signal-averaged spectra. Magn Reson Med 40: 327-9, 1998. [Abs] Spencer, R.G., Cox, T.S., Kaplan, P.W.: Global T-wave inversion associated with nonconvulsive status epilepticus. Ann Intern Med 129: 163-4, 1998. [Abs] Srivastava, R.K., Srivastava, A.R., Korsmeyer, S.J., Nesterova, M., Cho-Chung, Y.S., Longo, D.L.: Involvement of microtubules in the regulation of Bcl2 phosphorylation and apoptosis through cyclic AMP-dependent protein kinase. Mol Cell Biol 18: 3509-17, 1998. [Abs] Stern, M.D.: Exploring local calcium feedback: trying to fool mother nature. J Gen Physiol 112: 259-62, 1998. [Abs] Tagamets, M.A., Horwitz, B.: Integrating electrophysiological and anatomical experimental data to create a large-scale model that simulates a delayed match-to-sample human brain imaging study. Cereb Cortex 8: 310-20, 1998. [Abs] Tchorzewski, M.T., Duncan, M.D., Nass, P., Qureshi, F.G., Gearhart, P.J., Winchurch, R., Harmon, J.W.: Characterization of an aFGF gene expression vector with therapeutic potential. J Surg Res 77: 99-103, 1998. [Abs] Teipel, S.J., Hampel, H., Alexander, G.E., Schapiro, M.B., Horwitz, B., Teichberg, D., Daley, E., Hippius, H., Moller, H.J., Rapoport, S.I.: Dissociation between corpus callosum atrophy and white matter pathology in Alzheimer's disease. Neurology 51: 1381-5, 1998. [Abs] Tian, Z.G., Woody, M.A., Sun, R., Welniak, L.A., Raziuddin, A., Funakoshi, S., Tsarfaty, G., Longo, D.L., Murphy, W.J.: Recombinant human growth hormone promotes hematopoietic reconstitution after syngeneic bone marrow transplantation in mice. Stem Cells 16: 193-9, 1998. [Abs] Torigoe, K., Harada, T., Kusaba, H., Uchiumi, T., Kohno, K., Green, E.D., Scherer, S.W., Tsui, L.C., Schlessinger, D., Kuwano, M., Wada, M.: Localization of 67 exons on a YAC contig spanning 1.5 Mb around the multidrug resistance gene region of human chromosome 7q21.1. Genomics 49: 14-22, 1998. [Abs] Trump, D., Dixon, P.H., Mumm, S., Wooding, C., Davies, K.E., Schlessinger, D., Whyte, M.P., Thakker, R. V.: Localisation of X linked recessive idiopathic hypoparathyroidism to a 1.5 Mb region on Xq26-q27. J Med Genet 35: 905-9, 1998. [Abs] Visser, M., Harris, T.B., Langlois, J., Hannan, M.T., Roubenoff, R., Felson, D.T., Wilson, P.W., Kiel, D.P.: Body fat and skeletal muscle mass in relation to physical disability in very old men and women of the Framingham Heart Study. J Gerontol A Biol Sci Med Sci 53: M214-21, 1998. [Abs] Visser, M., Kiel, D.P., Langlois, J., Hannan, M.T., Felson, D.T., Wilson, P.W., Harris, T.B.: Muscle mass and fat mass in relation to bone mineral density in very old men and women: the Framingham Heart Study. Appl Radiat Isot 49: 745-7, 1998. [Abs] Visser, M., Langlois, J., Guralnik, J.M., Cauley, J.A., Kronmal, R.A., Robbins, J., Williamson, J.D., Harris, T.B.: High body fatness, but not low fat-free mass, predicts disability in older men and women: the Cardiovascular Health Study. Am J Clin Nutr 68: 584-90, 1998. [Abs] Wakisaka, A., Tanaka, H., Barnes, J., Liang, C.T.: Effect of locally infused IGF-I on femoral gene expression and bone turnover activity in old rats. J Bone Miner Res 13: 13-9, 1998. [Abs] Wang, W., Tony, T.: Methylation of bcl-2 gene in the apoptosis of mouse fibroblast and MCF-7 cells lines. Chinese Journal of Biochemistry and Molecular Biology 14: 309-313, 1998. Wang, W., Tony, T.: The expression of c-34B-2 on apoptotic process. Chinese Journal of Biochemistry and Molecular Biology 14: 314-317, 1998. Wang, W., Tony, T.: The time order of p53 and bcl-2 gene expression in the apoptotic process of mouse fibroblast cell lines. Chinese Journal of Biochemistry and Molecular Biology 14: 294-297, 1998. Wang, W., Chi, T., Xue, Y., Zhou, S., Kuo, A., Crabtree, G.R.: Architectural DNA binding by a high-mobility-group/kinesin-like subunit in mammalian SWI/SNF-related complexes. Proc Natl Acad Sci USA 95: 492-8, 1998. [Abs] Wang, X., Martindale, J.L., Liu, Y., Holbrook, N.J.: The cellular response to oxidative stress: influences of mitogen- activated protein kinase signalling pathways on cell survival. Biochem J 333: 291-300, 1998. [Abs] Weng, N.P., Hathcock, K.S., Hodes, R.J.: Regulation of telomere length and telomerase in T and B cells: a mechanism for maintaining replicative potential. Immunity 9: 151-7, 1998. [Abs] Williams, B.L., Schreiber, K.L., Zhang, W., Wange, R.L., Samelson, L.E., Leibson, P.J., Abraham, R.T.: Genetic evidence for differential coupling of Syk family kinases to the T-cell receptor: reconstitution studies in a ZAP-70-deficient Jurkat T- cell line. Mol Cell Biol 18: 1388-99, 1998. [Abs] Williams, W.M., Hayakawa, T., Grange, E., Rapoport, S.I.: Arecoline stimulation of radiolabeled arachidonate incorporation from plasma into brain microvessels of awake rat. Neurochem Res 23: 551-5, 1998. [Abs] Winter, D.B., Gearhart, P.J.: Dual enigma of somatic hypermutation of immunoglobulin variable genes: targeting and mechanism. Immunol Rev 162: 89-96, 1998. [Abs] Winter, D.B., Gearhart, P.J., Bohr, V.A.: Homogeneous rate of degradation of nuclear DNA during apoptosis. Nucleic Acids Res 26: 4422-5, 1998. [Abs] Winter, D.B., Phung, Q.H., Umar, A., Baker, S.M., Tarone, R.E., Tanaka, K., Liskay, R.M., Kunkel, T.A., Bohr, V.A., Gearhart, P.J.: Altered spectra of hypermutation in antibodies from mice deficient for the DNA mismatch repair protein PMS2. Proc Natl Acad Sci USA 95: 6953-8, 1998. [Abs] Winter, D.B., Sattar, N., Gearhart, P.J.: The role of promoter-intron interactions in directing hypermutation. Curr Top Microbiol Immunol 229: 1-10, 1998. [Abs] Wong, K., Boheler, K.R., Bishop, J., Petrou, M., Yacoub, M.H.: Clenbuterol induces cardiac hypertrophy with normal functional, morphological and molecular features. Cardiovasc Res 37: 115-22, 1998. [Abs] Wu, Z., Kinslow, C., Pettigrew, K.D., Rapoport, S.I., Schapiro, M.B.: Role of familial factors in late-onset Alzheimer disease as a function of age. Alzheimer Dis Assoc Disord 12: 190-7, 1998. [Abs] Xiao, R.P., Tomhave, E.D., Wang, D.J., Ji, X., Boluyt, M.O., Cheng, H., Lakatta, E.G., Koch, W.J.: Age-associated reductions in cardiac beta1- and beta2-adrenergic responses without changes in inhibitory G proteins or receptor kinases. J Clin Invest 101: 1273-82, 1998. [Abs] Yancik, R., Wesley, M.N., Ries, L.A., Havlik, R.J., Long, S., Edwards, B.K., Yates, J. W.: Comorbidity and age as predictors of risk for early mortality of male and female colon carcinoma patients: a population-based study. Cancer 82: 2123-34, 1998. [Abs] Yang, H., Egan, J.M., Wang, Y., Moyes, C.D., Roth, J., Montrose, M.H., Montrose-Rafizadeh, C.: GLP-1 action in L6 myotubes is via a receptor different from the pancreatic GLP-1 receptor. Am J Physiol 275: C675-83, 1998. [Abs] Yang, J., McCrae, R.R., Costa, P.T., Jr.: Adult age differences in personality traits in the United States and the People's Republic of China. J Gerontol B Psychol Sci Soc Sci 53: 375-83, 1998. [Abs] Yoe, J., Gause, B.L., Curti, B.D., Longo, D.L., Bagg, A., Kopp, W.C., Janik, J.E.: Development of rheumatoid arthritis after treatment of large granular lymphocyte leukemia with deoxycoformycin. Am J Hematol 57: 253-7, 1998. [Abs] Yotsumoto, S., Shimada, T., Cui, C.Y., Nakashima, H., Fujiwara, H., Ko, M.S.H.: Expression of adrenomedullin, a hypotensive peptide, in the trophoblast giant cells at the embryo implantation site in mouse. Dev Biol 203: 264-75, 1998. [Abs] Yu, Q., Greig, N.H., Holloway, H.W., Brossi, A.: Syntheses and anticholinesterase activities of (3aS)-N1, N8- bisnorphenserine, (3aS)-N1,N8-bisnorphysostigmine, their antipodal isomers, and other potential metabolites of phenserine. J Med Chem 41: 2371-9, 1998. [Abs] Zea, A.H., Ochoa, M.T., Ghosh, P., Longo, D.L., Alvord, W.G., Valderrama, L., Falabella, R., Harvey, L.K., Saravia, N., Moreno, L.H., Ochoa, A.C.: Changes in expression of signal transduction proteins in T lymphocytes of patients with leprosy. Infect Immun 66: 499-504, 1998. [Abs] Zhao, K., Wang, W., Rando, O.J., Xue, Y., Swiderek, K., Kuo, A., Crabtree, G.R.: Rapid and phosphoinositol-dependent binding of the SWI/SNF-like BAF complex to chromatin after T lymphocyte receptor signaling. Cell 95: 625-36, 1998. [Abs] Zheng, J.S., O'Neill, L., Long, X., Webb, T.E., Barnard, E.A., Lakatta, E.G., Boluyt, M.O.: Stimulation of P2Y receptors activates c-fos gene expression and inhibits DNA synthesis in cultured cardiac fibroblasts. Cardiovasc Res 37: 718-28, 1998. [Abs] Zhou, Y.Y., Lakatta, E.G., Xiao, R.P.: Age-associated alterations in calcium current and its modulation in cardiac myocytes. Drugs Aging 13: 159-71, 1998. [Abs] Ziegelstein, R.C., Blank, P.S., Cheng,L., Capogrossi, M.C.: Cytosolic alkalinization of vascular endothelial cells produced by an abrupt reduction in fluid shear stress. Circ Res 82: 803-9, 1998. [Abs]

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