| | Staff Scientists and Clinicians
| Kathleen C. Schmidt, M.A. |
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Ms.
Schmidt is an applied mathematician in the Section on Neuroadaptation and Protein Metabolism of the Intramural Research
Program, National Institute of Mental Health in Bethesda,
Maryland. She received her M.A. in mathematics from the
University of Maryland where she studied numerical linear
algebra with G.W. Stewart. She joined the Laboratory of
Cerebral Metabolism in 1983 to work with Louis Sokoloff
on quantitative in vivo imaging techniques. |
| Research Interests |
| Ms. Schmidt's work centers on the development and analysis of kinetic models of tracers used for the measurement of regional cerebral blood flow, glucose metabolism, and protein synthesis by Positron Emission Tomography and quantitative autoradiographic techniques. |
| Representative Selected Recent Publications: |
- Schmidt K.: Can normalized tissue activities be used instead of absolute blood flow measurements in the brain? Eur J Nucl Med 29:953-956, 2002.
- Schmidt KC, Turkheimer FE.: Kinetic modeling in positron emission tomography. Q J Nucl Med 46:70-85, 2002.
- Schmidt KC, Sokoloff L. A: computationally efficient algorithm for determining regional cerebral blood flow in heterogeneous tissues by positron emission tomography. IEEE Transactions on Medical Imaging, 20(7):618-632, 2001.
- Schmidt K.: Which linear compartmental systems can be analyzed by spectral analysis of PET output data summed over all compartments? J Cereb Blood Flow Metab, 19:560-569, 1999.
- Turkheimer F, Sokoloff L, Bertoldo A, Lucignani G, Reivich M, Jaggi JL, Schmidt K. Estimation of component and parameter distributions in spectral analysis. J Cereb Blood Flow Metab, 18:1211-1222, 1998.
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