NIH Clinical Research Studies Listed By Institute of the Principal Investigator

National Institutes of Health Clinical Center (CC)

56 Protocols (35 Active Accrual of new subjects, 21 Follow-up of previously enrolled subjects)


Active Accrual, Protocols Recruiting New Patients 
* 08-CC-0220:
A Phase II Clinical Trial to Determine the Effectiveness of Problem Solving Education in Caregivers and Patients During Allogeneic HSCT

* 08-CC-0205:
Evaluation of Assessments of Motor Performance, Physical Impairments and Functional Abilities

* 08-CC-0193:
Research Participant Perception of Care Project: Part 1: Focus Groups of Research Participants and Research Professionals to Identify Key Dimensions of the Research Participant Experience

* 08-CC-0133:
Response and Adaptation to Aerobic Exercise in Patients with Pulmonary Hypertension: Initial Studies for Establishing Guidelines

* 08-CC-0127:
Communicating a Cancer Diagnosis: Current Methods and Their Effects

* 08-CC-0032:
Parental Permission and Adolescent Assent and Decision Making in Clinical Research

* 08-CC-0024:
Immunologic and Virologic Response in HIV Infected HLA-B*57 Progressors after Infusion of Lymphocytes from HIV Infected HLA-B*57 "Elite" Long-Term-Nonprogressors

* 07-CC-0153:
Effects of Peripheral Blood Stem Cell Transplantation on the Microbial Flora of the Oral Cavity

* 07-CC-0090:
Molecular Changes and Biomarkers in Chronic Myeloproliferative Disorders

* 07-CC-0011:
Hypnosis as a Pain and Symptom Management Strategy in Patients with Sickle Cell Disease

* 06-CC-0166:
Iron Replacement in Blood Donors

* 05-CC-0216:
Prospective Assessment of Functional Status, Psychosocial Adjustment, Health Related Quality of Life and the Symptom Experience in Patients Treated with Allogeneic Hematopoietic Stem Cell Transplantation

* 05-CC-0091:
Electromagnetic Tracking of Devices during Interventional Procedures: A Pilot Study

* 05-CC-0082:
The Influence of Concurrent Administration of Echinacea Purpurea, Ginkgo Biloba, or Panax Ginseng on the Steady State Pharmacokinetic Profile of Lopinavir/ritonavir in Healthy Volunteers

* 05-CC-0062:
Evaluation of Patients with Critical Illness: Intensive Care Training Protocol

* 05-CC-0041:
Endothelial Cell Dysfunction in Pulmonary Arterial Hypertension: Biomarkers, Mechanisms of Disease and Novel Therapeutic Targets

* 04-CC-0178:
The Treatment of Deep Vein Thrombosis of the Lower Extremities with "Low-Dose" Alteplase: a Pilot Study

* 04-CC-0119:
Biomarkers and Protein Mass Expression Profiles in Bronchoalveolar Lavage from Patients with Lung Infiltrates

* 03-CC-0128:
Development and Evaluation of Techniques for Computer Aided Detection and Diagnosis from Radiologic Images

* 03-CC-0015:
Collection of Blood from Volunteers and Patients for Studies of Endothelial Function and Systemic Inflammation

* 02-CC-0266:
Acute Cardiac Allograft Cellular Rejection and Cardiac Allograft Vasculopathy: Identification of Diagnostic Biomarkers and Target Pathways for Preventive Therapy

* 02-CC-0247:
Values at the Bedside: A Survey of European Physicians Regarding Ethical Dilemmas in Clinical Practice

* 02-CC-0245:
The Natural History of Upper Trapezius Myofascial Trigger Points: Comparison of Local and Remote Tissue Milieu in Normal Muscle, Latent and Active Myofascial Trigger Points Over Time

* 02-CC-0045:
A Prospective (Cohort) Study to Identify Factors Affecting Morbidity Following the Diagnosis and Treatment of Patients with Breast Cancer: A Multi-Institutional Study Between NIH/RMD and NNMC/BCC

* 01-CC-0231:
A Prospective Study of Transfusion-Transmitted Infections

* 01-CC-0045:
Studies of Phlebotomy Therapy in Hereditary Hemochromatosis

* 00-CC-0165:
Filgrastim-Mobilized Peripheral Blood Stem Cells for Primary Allogeneic Transplantation Using Unrelated Donors Participating in the National Marrow Donor Program (NMDP)

* 99-CC-0168:
Collection and Distribution of Blood Components from Healthy Donors for In Vitro Research Use

* 99-CC-0163:
Functional and Metabolic Imaging Using Magnetic Resonance at 3.0 Tesla

* 98-CC-0090:
Evaluation of Hematologic Patients - Training Protocol

* 98-CC-0019:
Normal Volunteer Scanning on MR

* 95-CC-0123:

* 91-CC-0117:
Epidemiology, Infectivity and Natural History of Hepatitis C Virus Infection in a Blood Donor Population

* 90-CC-0168:
A Rigid Body Data Base on Human Movement

* 87-CC-0091:
Nuclear Magnetic Resonance Imaging/Spectroscopy at 1.5 and 3.0 Tesla

Active Follow-up, Protocols NOT Recruiting New Patients 

* 07-CC-0125:
Pilot Study of the Incidence of HLA Class I and Class II Antibodies in Platelet Donors and their Effects on the Transfusion Recipient

* 07-CC-0067:
A Feasibility Study to Test an Individualized Dyadic Problem-Solving Education Intervention to Improve Problem-Solving Skills of Patients and Family Caregivers During Allogeneic HSCT

* 07-CC-0015:
Exploring Decision Making of Hispanics and African Americans with HIV/AIDS Participating in Clinical Trials

* 05-CC-0246:
The Evaluation of Focal Contrast-Enhancing Brain Lesions in HIV-Infected Patients

* 05-CC-0093:
The Effect of Animal-Assisted Therapy on Oncology Patients Being Treated for Pain

* 05-CC-0042:
Coupled Joint Proprioception and Multi-Joint Movement in the Lower Extremity: A Pilot Study

* 05-CC-0012:
Effects of Inhaled Carbon Monoxide on Pulmonary Inflammatory Responses Following Endotoxin Instillation

* 05-CC-0008:
Revising Employee Benefits for the Sake of Health

* 04-CC-0184:
Influence of MDR-1 CYP3A4 and CYP3A5 Genotypes/Haplotypes on Sirolimus Pharmacokinetics and Pharmacodynamics in Patients with Renal Transplantation

* 04-CC-0130:
The Effect of a Systemic Oral Care Program on Reducing Exposure to Oropharyngeal Pathogens in Critically III Patients

* 04-CC-0070:
Exploring Patient-Provider Trust among Individuals with End-Stage Renal Disease

* 04-CC-0046:
Citrate Effects and Bone Density Studies in Long-Term Apheresis Donors

* 04-CC-0032:
Atorvastatin Therapy To Improve Endothelial Function in Sickle Cell Disease

* 03-CC-0306:
A Phase I/II Randomized, Placebo-Controlled Trial to Assess the Safety and Efficacy of Intravenous Immunoglobulin G (Omr-IgG-am) Containing High Anti-West Nile Virus Antibody Titers in Patients with, or at High Risk for Progression to West Nile Virus(WNV

* 03-CC-0305:
Investigation of the Natural History of West Nile Virus Infection in Patients with Recently Acquired West Nile Fever or Neuroinvasive Disease

* 03-CC-0301:
Health Beliefs and Health Behavior Practices among Minorities with Rheumatic Diseases

* 03-CC-0127:
Evaluation of Potential Synergy of Combining Hydroxyurea with Nitric Oxide Donors on Fetal Hemoglobin Synthesis in Patients with Sickle Cell Anemia

* 03-CC-0091:
Global Initiative to Characterize Differences in Antiretroviral Pharmacokinetics in HIV-Infected Populations

* 03-CC-0052:
Influence of MDR1 Genotype on Indinavir and Saquinavir Pharmacokinetics in Healthy Volunteers

* 02-CC-0044:
Morbidity Following the Diagnosis and Treatment of Patients with Breast Cancer: A Multi-Institutional Study Between the National Institutes of Health (NIH) Rehabilitation Medicine Department (RMD) and the National Naval Medical Center (NNMC) Breast Care

* 92-CC-0141:
The Cardiopulmonary Effects of Endotoxin in Normal Human Volunteers

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