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Volume 2(1-2);  Jan–Feb 2009
In This Issue
Shedding light on chronic Listeria infection
Dis Model Mech. 2009 Jan–Feb; 2(1-2): 1.
PMCID: PMC2615161
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Costello syndrome modeled in zebrafish
Dis Model Mech. 2009 Jan–Feb; 2(1-2): 1.
PMCID: PMC2615180
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MDM2 variant found in tumors paradoxically promotes cell death
Dis Model Mech. 2009 Jan–Feb; 2(1-2): 1.
PMCID: PMC2615157
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Basis of deafness in Waardenburg syndrome
Dis Model Mech. 2009 Jan–Feb; 2(1-2): 1.
PMCID: PMC2615169
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Yeast model of lysosomal disorders
Dis Model Mech. 2009 Jan–Feb; 2(1-2): 1.
PMCID: PMC2615178
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Research Highlights
Connective tissue disorders: kinase causes progressive ossification in soft tissue
Dis Model Mech. 2009 Jan–Feb; 2(1-2): 2.
PMCID: PMC2615177
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Development: zebrafish used in identifying a novel neurocutaneous syndrome
Dis Model Mech. 2009 Jan–Feb; 2(1-2): 2.
PMCID: PMC2615174
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Cardiac disease: Ca signaling mechanism underlies cardiomyopathy and arrhythmia
Dis Model Mech. 2009 Jan–Feb; 2(1-2): 2.
PMCID: PMC2615173
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Cancer: protein processing aids the spread of malignant gliomas
Dis Model Mech. 2009 Jan–Feb; 2(1-2): 2–3.
PMCID: PMC2615165
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Neurodegeneration: early childhood disease modeled in flies
Dis Model Mech. 2009 Jan–Feb; 2(1-2): 3.
PMCID: PMC2615179
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Immunology: empowering CD8 cells to combat autoimmune disease
Dis Model Mech. 2009 Jan–Feb; 2(1-2): 3.
PMCID: PMC2615168
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Editorial
I kid you not
Vivian Siegel
Dis Model Mech. 2009 Jan–Feb; 2(1-2): 5–6. doi: 10.1242/dmm.002352.
PMCID: PMC2615159
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Community News
Editors’ clubs benefit researchers and trainees
Elizabeth H. Catania and Kevin T. Seale
Dis Model Mech. 2009 Jan–Feb; 2(1-2): 7. doi: 10.1242/dmm.002279.
PMCID: PMC2615154
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DMM awards travel funds to early-career researchers
Dis Model Mech. 2009 Jan–Feb; 2(1-2): 8. doi: 10.1242/dmm.002329.
PMCID: PMC2615175
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USEFUL WEBSITES: Zotero puts a new spin on citation management, and more
Dis Model Mech. 2009 Jan–Feb; 2(1-2): 8. doi: 10.1242/dmm.002337.
PMCID: PMC2615151
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A Model For Life
The birth of cloning: an interview with John Gurdon
Kristin Kain
Dis Model Mech. 2009 Jan–Feb; 2(1-2): 9–10. doi: 10.1242/dmm.002014.
PMCID: PMC2615171
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Book & Art Review
Life as a major groove: riffing on the art of biology
Daria Siekhaus
Dis Model Mech. 2009 Jan–Feb; 2(1-2): 11. doi: 10.1242/dmm.002295.
PMCID: PMC2615176
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Clinical Puzzle
Disease modeling for Ebola and Marburg viruses
Dennis Bente, Jason Gren, James E. Strong, and Heinz Feldmann
Dis Model Mech. 2009 Jan–Feb; 2(1-2): 12–17. doi: 10.1242/dmm.000471.
PMCID: PMC2615158
Primer
Fishing for the genetic basis of cardiovascular disease
Tillman Dahme, Hugo A. Katus, and Wolfgang Rottbauer
Dis Model Mech. 2009 Jan–Feb; 2(1-2): 18–22. doi: 10.1242/dmm.000687.
PMCID: PMC2615162
Perspective
Progenitor cell therapies for traumatic brain injury: barriers and opportunities in translation
Peter A. Walker, Shinil K. Shah, Matthew T. Harting, and Charles S. Cox, Jr
Dis Model Mech. 2009 Jan–Feb; 2(1-2): 23–38. doi: 10.1242/dmm.001198.
PMCID: PMC2615170
Research Articles
Foci of Listeria monocytogenes persist in the bone marrow
Jonathan Hardy, Pauline Chu, and Christopher H. Contag
Dis Model Mech. 2009 Jan–Feb; 2(1-2): 39–46. Published online 2008 December 22. doi: 10.1242/dmm.000836.
PMCID: PMC2615163
TRANSLATIONAL IMPACT
Dis Model Mech. 2009 Jan–Feb; 2(1-2): 45. doi: 10.1242/dmm.002220.
PMCID: PMC2615153
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MDM2-A, a common Mdm2 splice variant, causes perinatal lethality, reduced longevity and enhanced senescence
Erin L. Volk, Katja Schuster, Katie M. Nemeth, Liying Fan, and Linda C. Harris
Dis Model Mech. 2009 Jan–Feb; 2(1-2): 47–55. Published online 2008 December 22. doi: 10.1242/dmm.000992.
PMCID: PMC2615166
TRANSLATIONAL IMPACT
Dis Model Mech. 2009 Jan–Feb; 2(1-2): 54. doi: 10.1242/dmm.002089.
PMCID: PMC2615155
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Expression of H-RASV12 in a zebrafish model of Costello syndrome causes cellular senescence in adult proliferating cells
Cristina Santoriello, Gianluca Deflorian, Federica Pezzimenti, Koichi Kawakami, Luisa Lanfrancone, Fabrizio d’Adda di Fagagna, and Marina Mione
Dis Model Mech. 2009 Jan–Feb; 2(1-2): 56–67. Published online 2008 December 22. doi: 10.1242/dmm.001016.
PMCID: PMC2615164
TRANSLATIONAL IMPACT
Dis Model Mech. 2009 Jan–Feb; 2(1-2): 66. doi: 10.1242/dmm.002238.
PMCID: PMC2615156
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A zebrafish model for Waardenburg syndrome type IV reveals diverse roles for Sox10 in the otic vesicle
Kirsten Dutton, Leila Abbas, Joanne Spencer, Claire Brannon, Catriona Mowbray, Masataka Nikaido, Robert N. Kelsh, and Tanya T. Whitfield
Dis Model Mech. 2009 Jan–Feb; 2(1-2): 68–83. Published online 2008 December 22. doi: 10.1242/dmm.001164.
PMCID: PMC2615172
TRANSLATIONAL IMPACT
Dis Model Mech. 2009 Jan–Feb; 2(1-2): 80. doi: 10.1242/dmm.002212.
PMCID: PMC2615152
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The fission yeast model for the lysosomal storage disorder Batten disease predicts disease severity caused by mutations in CLN3
Rebecca L. Haines, Sandra Codlin, and Sara E. Mole
Dis Model Mech. 2009 Jan–Feb; 2(1-2): 84–92. Published online 2008 December 22. doi: 10.1242/dmm.000851.
PMCID: PMC2615160
TRANSLATIONAL IMPACT
Dis Model Mech. 2009 Jan–Feb; 2(1-2): 91. doi: 10.1242/dmm.002246.
PMCID: PMC2615167
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