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Volume 5(1);  January 2009
Opinion
The Sicker Sex
Marlene Zuk
PLoS Pathog. 2009 January; 5(1): e1000267. Published online 2009 January 30. doi: 10.1371/journal.ppat.1000267.
PMCID: PMC2628977
Research Articles
Transmission of Influenza Virus in a Mammalian Host Is Increased by PB2 Amino Acids 627K or 627E/701N
John Steel, Anice C. Lowen, Samira Mubareka, and Peter Palese
PLoS Pathog. 2009 January; 5(1): e1000252. Published online 2009 January 2. doi: 10.1371/journal.ppat.1000252.
PMCID: PMC2603332
Quantitative Models of In Vitro Bacteriophage–Host Dynamics and Their Application to Phage Therapy
Benjamin J. Cairns, Andrew R. Timms, Vincent A. A. Jansen, Ian F. Connerton, and Robert J. H. Payne
PLoS Pathog. 2009 January; 5(1): e1000253. Published online 2009 January 2. doi: 10.1371/journal.ppat.1000253.
PMCID: PMC2603284
Positive Selection Results in Frequent Reversible Amino Acid Replacements in the G Protein Gene of Human Respiratory Syncytial Virus
Viviane F. Botosso, Paolo M. de A. Zanotto, Mirthes Ueda, Eurico Arruda, Alfredo E. Gilio, Sandra E. Vieira, Klaus E. Stewien, Teresa C. T. Peret, Leda F. Jamal, Maria I. de M. C. Pardini, João R. R. Pinho, Eduardo Massad, Osvaldo A. Sant'Anna, Eddie C. Holmes, Edison L. Durigon, and and the VGDN Consortium
PLoS Pathog. 2009 January; 5(1): e1000254. Published online 2009 January 2. doi: 10.1371/journal.ppat.1000254.
PMCID: PMC2603285
The Epstein-Barr Virus G-Protein-Coupled Receptor Contributes to Immune Evasion by Targeting MHC Class I Molecules for Degradation
Jianmin Zuo, Andrew Currin, Bryan D. Griffin, Claire Shannon-Lowe, Wendy A. Thomas, Maaike E. Ressing, Emmanuel J. H. J. Wiertz, and Martin Rowe
PLoS Pathog. 2009 January; 5(1): e1000255. Published online 2009 January 2. doi: 10.1371/journal.ppat.1000255.
PMCID: PMC2603334
An Upstream Open Reading Frame Controls Translation of var2csa, a Gene Implicated in Placental Malaria
Borko Amulic, Ali Salanti, Thomas Lavstsen, Morten A. Nielsen, and Kirk W. Deitsch
PLoS Pathog. 2009 January; 5(1): e1000256. Published online 2009 January 2. doi: 10.1371/journal.ppat.1000256.
PMCID: PMC2603286
Role of Intraspecies Recombination in the Spread of Pathogenicity Islands within the Escherichia coli Species
Sören Schubert, Pierre Darlu, Olivier Clermont, Andreas Wieser, Giuseppe Magistro, Christiane Hoffmann, Kirsten Weinert, Olivier Tenaillon, Ivan Matic, and Erick Denamur
PLoS Pathog. 2009 January; 5(1): e1000257. Published online 2009 January 9. doi: 10.1371/journal.ppat.1000257.
PMCID: PMC2606025
A Role for the Unfolded Protein Response (UPR) in Virulence and Antifungal Susceptibility in Aspergillus fumigatus
Daryl L. Richie, Lukas Hartl, Vishukumar Aimanianda, Michael S. Winters, Kevin K. Fuller, Michael D. Miley, Stephanie White, Jason W. McCarthy, Jean-Paul Latgé, Marta Feldmesser, Judith C. Rhodes, and David S. Askew
PLoS Pathog. 2009 January; 5(1): e1000258. Published online 2009 January 9. doi: 10.1371/journal.ppat.1000258.
PMCID: PMC2606855
A Novel Co-Crystal Structure Affords the Design of Gain-of-Function Lentiviral Integrase Mutants in the Presence of Modified PSIP1/LEDGF/p75
Stephen Hare, Ming-Chieh Shun, Saumya Shree Gupta, Eugene Valkov, Alan Engelman, and Peter Cherepanov
PLoS Pathog. 2009 January; 5(1): e1000259. Published online 2009 January 9. doi: 10.1371/journal.ppat.1000259.
PMCID: PMC2606027
Control of Stochastic Gene Expression by Host Factors at the HIV Promoter
John C. Burnett, Kathryn Miller-Jensen, Priya S. Shah, Adam P. Arkin, and David V. Schaffer
PLoS Pathog. 2009 January; 5(1): e1000260. Published online 2009 January 9. doi: 10.1371/journal.ppat.1000260.
PMCID: PMC2607019
Genomic Survey of the Non-Cultivatable Opportunistic Human Pathogen, Enterocytozoon bieneusi
Donna E. Akiyoshi, Hilary G. Morrison, Shi Lei, Xiaochuan Feng, Quanshun Zhang, Nicolas Corradi, Harriet Mayanja, James K. Tumwine, Patrick J. Keeling, Louis M. Weiss, and Saul Tzipori
PLoS Pathog. 2009 January; 5(1): e1000261. Published online 2009 January 9. doi: 10.1371/journal.ppat.1000261.
PMCID: PMC2607024
Distinct Roles of Plasmodium Rhomboid 1 in Parasite Development and Malaria Pathogenesis
Prakash Srinivasan, Isabelle Coppens, and Marcelo Jacobs-Lorena
PLoS Pathog. 2009 January; 5(1): e1000262. Published online 2009 January 16. doi: 10.1371/journal.ppat.1000262.
PMCID: PMC2607553
miR-198 Inhibits HIV-1 Gene Expression and Replication in Monocytes and Its Mechanism of Action Appears To Involve Repression of Cyclin T1
Tzu-Ling Sung and Andrew P. Rice
PLoS Pathog. 2009 January; 5(1): e1000263. Published online 2009 January 16. doi: 10.1371/journal.ppat.1000263.
PMCID: PMC2607557
Imbalanced Lignin Biosynthesis Promotes the Sexual Reproduction of Homothallic Oomycete Pathogens
Michaël Quentin, Valérie Allasia, Anthony Pegard, Florent Allais, Paul-Henri Ducrot, Bruno Favery, Caroline Levis, Sophie Martinet, Clarissa Masur, Michel Ponchet, Dominique Roby, Nikolaus L. Schlaich, Lise Jouanin, and Harald Keller
PLoS Pathog. 2009 January; 5(1): e1000264. Published online 2009 January 16. doi: 10.1371/journal.ppat.1000264.
PMCID: PMC2613516
Malaria Parasite Invasion of the Mosquito Salivary Gland Requires Interaction between the Plasmodium TRAP and the Anopheles Saglin Proteins
Anil K. Ghosh, Martin Devenport, Deepa Jethwaney, Dario E. Kalume, Akhilesh Pandey, Vernon E. Anderson, Ali A. Sultan, Nirbhay Kumar, and Marcelo Jacobs-Lorena
PLoS Pathog. 2009 January; 5(1): e1000265. Published online 2009 January 16. doi: 10.1371/journal.ppat.1000265.
PMCID: PMC2613030
Parasitic Nematodes Modulate PIN-Mediated Auxin Transport to Facilitate Infection
Wim Grunewald, Bernard Cannoot, Jiří Friml, and Godelieve Gheysen
PLoS Pathog. 2009 January; 5(1): e1000266. Published online 2009 January 16. doi: 10.1371/journal.ppat.1000266.
PMCID: PMC2613529
Gain of Function Mutations in CgPDR1 of Candida glabrata Not Only Mediate Antifungal Resistance but Also Enhance Virulence
Sélène Ferrari, Françoise Ischer, David Calabrese, Brunella Posteraro, Maurizio Sanguinetti, Giovanni Fadda, Bettina Rohde, Christopher Bauser, Oliver Bader, and Dominique Sanglard
PLoS Pathog. 2009 January; 5(1): e1000268. Published online 2009 January 16. doi: 10.1371/journal.ppat.1000268.
PMCID: PMC2607542
Genomic Analysis Reveals a Potential Role for Cell Cycle Perturbation in HCV-Mediated Apoptosis of Cultured Hepatocytes
Kathie-Anne Walters, Andrew J. Syder, Sharon L. Lederer, Deborah L. Diamond, Bryan Paeper, Charles M. Rice, and Michael G. Katze
PLoS Pathog. 2009 January; 5(1): e1000269. Published online 2009 January 16. doi: 10.1371/journal.ppat.1000269.
PMCID: PMC2613535
Rab11A-Controlled Assembly of the Inner Membrane Complex Is Required for Completion of Apicomplexan Cytokinesis
Carolina Agop-Nersesian, Bernina Naissant, Fathia Ben Rached, Manuel Rauch, Angelika Kretzschmar, Sabine Thiberge, Robert Menard, David J. P. Ferguson, Markus Meissner, and Gordon Langsley
PLoS Pathog. 2009 January; 5(1): e1000270. Published online 2009 January 23. doi: 10.1371/journal.ppat.1000270.
PMCID: PMC2622761
The IpaC Carboxyterminal Effector Domain Mediates Src-Dependent Actin Polymerization during Shigella Invasion of Epithelial Cells
Joëlle Mounier, Michel R. Popoff, Jost Enninga, Margaret C. Frame, Philippe J. Sansonetti, and Guy Tran Van Nhieu
PLoS Pathog. 2009 January; 5(1): e1000271. Published online 2009 January 23. doi: 10.1371/journal.ppat.1000271.
PMCID: PMC2621354
Immunization with Single-Cycle SIV Significantly Reduces Viral Loads After an Intravenous Challenge with SIVmac239
Bin Jia, Sharon K. Ng, M. Quinn DeGottardi, Michael Piatak, Jr., Eloísa Yuste, Angela Carville, Keith G. Mansfield, Wenjun Li, Barbra A. Richardson, Jeffrey D. Lifson, and David T. Evans
PLoS Pathog. 2009 January; 5(1): e1000272. Published online 2009 January 23. doi: 10.1371/journal.ppat.1000272.
PMCID: PMC2621341
An Inhibitory Antibody Blocks Interactions between Components of the Malarial Invasion Machinery
Christine R. Collins, Chrislaine Withers-Martinez, Fiona Hackett, and Michael J. Blackman
PLoS Pathog. 2009 January; 5(1): e1000273. Published online 2009 January 23. doi: 10.1371/journal.ppat.1000273.
PMCID: PMC2621342
Inflammatory Genital Infections Mitigate a Severe Genetic Bottleneck in Heterosexual Transmission of Subtype A and C HIV-1
Richard E. Haaland, Paulina A. Hawkins, Jesus Salazar-Gonzalez, Amber Johnson, Amanda Tichacek, Etienne Karita, Olivier Manigart, Joseph Mulenga, Brandon F. Keele, George M. Shaw, Beatrice H. Hahn, Susan A. Allen, Cynthia A. Derdeyn, and Eric Hunter
PLoS Pathog. 2009 January; 5(1): e1000274. Published online 2009 January 23. doi: 10.1371/journal.ppat.1000274.
PMCID: PMC2621345
Viral Mimicry of Cdc2/Cyclin-Dependent Kinase 1 Mediates Disruption of Nuclear Lamina during Human Cytomegalovirus Nuclear Egress
Sofia Hamirally, Jeremy P. Kamil, Yasmine M. Ndassa-Colday, Alison J. Lin, Wan Jin Jahng, Moon-Chang Baek, Sarah Noton, Laurie A. Silva, Martha Simpson-Holley, David M. Knipe, David E. Golan, Jarrod A. Marto, and Donald M. Coen
PLoS Pathog. 2009 January; 5(1): e1000275. Published online 2009 January 23. doi: 10.1371/journal.ppat.1000275.
PMCID: PMC2625439
Trypanosome Lytic Factor, an Antimicrobial High-Density Lipoprotein, Ameliorates Leishmania Infection
Marie Samanovic, Maria Pilar Molina-Portela, Anne-Danielle C. Chessler, Barbara A. Burleigh, and Jayne Raper
PLoS Pathog. 2009 January; 5(1): e1000276. Published online 2009 January 23. doi: 10.1371/journal.ppat.1000276.
PMCID: PMC2622765
The Cell Adhesion Molecule “CAR” and Sialic Acid on Human Erythrocytes Influence Adenovirus In Vivo Biodistribution
Elena Seiradake, Daniel Henaff, Harald Wodrich, Olivier Billet, Matthieu Perreau, Claire Hippert, Franck Mennechet, Guy Schoehn, Hugues Lortat-Jacob, Hanna Dreja, Sandy Ibanes, Vasiliki Kalatzis, Jennifer P. Wang, Robert W. Finberg, Stephen Cusack, and Eric J. Kremer
PLoS Pathog. 2009 January; 5(1): e1000277. Published online 2009 January 2. doi: 10.1371/journal.ppat.1000277.
PMCID: PMC2607015
A Legionella pneumophila Effector Protein Encoded in a Region of Genomic Plasticity Binds to Dot/Icm-Modified Vacuoles
Shira Ninio, Jean Celli, and Craig R. Roy
PLoS Pathog. 2009 January; 5(1): e1000278. Published online 2009 January 23. doi: 10.1371/journal.ppat.1000278.
PMCID: PMC2621349
Selective Transmission of R5 HIV-1 over X4 HIV-1 at the Dendritic Cell–T Cell Infectious Synapse Is Determined by the T Cell Activation State
Takuya Yamamoto, Yasuko Tsunetsugu-Yokota, Yu-ya Mitsuki, Fuminori Mizukoshi, Takatsugu Tsuchiya, Kazutaka Terahara, Yoshio Inagaki, Naoki Yamamoto, Kazuo Kobayashi, and Jun-ichiro Inoue
PLoS Pathog. 2009 January; 5(1): e1000279. Published online 2009 January 30. doi: 10.1371/journal.ppat.1000279.
PMCID: PMC2627922
Rotavirus NSP1 Inhibits NFκB Activation by Inducing Proteasome-Dependent Degradation of β-TrCP: A Novel Mechanism of IFN Antagonism
Joel W. Graff, Khalil Ettayebi, and Michele E. Hardy
PLoS Pathog. 2009 January; 5(1): e1000280. Published online 2009 January 30. doi: 10.1371/journal.ppat.1000280.
PMCID: PMC2627925
Estimation of Transmission Parameters of H5N1 Avian Influenza Virus in Chickens
Annemarie Bouma, Ivo Claassen, Ketut Natih, Don Klinkenberg, Christl A. Donnelly, Guus Koch, and Michiel van Boven
PLoS Pathog. 2009 January; 5(1): e1000281. Published online 2009 January 30. doi: 10.1371/journal.ppat.1000281.
PMCID: PMC2627927
Local Inflammation Induces Complement Crosstalk Which Amplifies the Antimicrobial Response
Jing Zhang, Jingyun Koh, Jinhua Lu, Steffen Thiel, Benjamin S. H. Leong, Sunil Sethi, Cynthia Y. X. He, Bow Ho, and Jeak L. Ding
PLoS Pathog. 2009 January; 5(1): e1000282. Published online 2009 January 30. doi: 10.1371/journal.ppat.1000282.
PMCID: PMC2629585
Diploids in the Cryptococcus neoformans Serotype A Population Homozygous for the α Mating Type Originate via Unisexual Mating
Xiaorong Lin, Sweta Patel, Anastasia P. Litvintseva, Anna Floyd, Thomas G. Mitchell, and Joseph Heitman
PLoS Pathog. 2009 January; 5(1): e1000283. Published online 2009 January 30. doi: 10.1371/journal.ppat.1000283.
PMCID: PMC2629120
Glutathione Provides a Source of Cysteine Essential for Intracellular Multiplication of Francisella tularensis
Khaled Alkhuder, Karin L. Meibom, Iharilalao Dubail, Marion Dupuis, and Alain Charbit
PLoS Pathog. 2009 January; 5(1): e1000284. Published online 2009 January 30. doi: 10.1371/journal.ppat.1000284.
PMCID: PMC2629122
Polar Localization of Virulence-Related Esx-1 Secretion in Mycobacteria
Fredric Carlsson, Shilpa A. Joshi, Linda Rangell, and Eric J. Brown
PLoS Pathog. 2009 January; 5(1): e1000285. Published online 2009 January 30. doi: 10.1371/journal.ppat.1000285.
PMCID: PMC2628743
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