| | Other Issues: previous | next | latest | archiveEditors' View Editors' view January 2008 J M Ritter PMCID: PMC2291263 Review Article Overview of the human pharmacokinetics of recombinant activated factor VII Thomas Klitgaard and Tina G Nielsen PMCID: PMC2291262 Pharmacokinetics and Pharmacodynamics Pharmacokinetics and clinical efficacy of lorazepam in children with severe malaria and convulsions Simon N Muchohi, Kenneth Obiero, Charles R J C Newton, Bernhards R Ogutu, Geoffrey Edwards, and Gilbert O Kokwaro PMCID: PMC2291276 The pharmacokinetics and effects of a long-acting preparation of superoxide dismutase (PC-SOD) in man F J F Broeyer, B E van Aken, J Suzuki, M J B Kemme, H C Schoemaker, A F Cohen, Y Mizushima, and J Burggraaf PMCID: PMC2291268 Population pharmacokinetic analysis of carboxyhaemoglobin concentrations in adult cigarette smokers Carol Cronenberger, Diane R Mould, Hans-Juergen Roethig, and Mohamadi Sarkar PMCID: PMC2291280 Effect of theophylline on the rate of moderate to severe exacerbations among patients with chronic obstructive pulmonary disease Marie-Christyne Cyr, Marie-France Beauchesne, Catherine Lemière, and Lucie Blais PMCID: PMC2291265 Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism Edzard Schwedhelm, Renke Maas, Ralf Freese, Donald Jung, Zoltan Lukacs, Alen Jambrecina, William Spickler, Friedrich Schulze, and Rainer H Böger PMCID: PMC2291275 Pharmacogenetics Interindividual variability in the concentration–effect relationship of antilymphocyte globulins—a possible influence of FcγRIIIa genetic polymorphism David Ternant, Matthias Büchler, Maud Bénéton, Gunnar Alván, Marc Ohresser, Guy Touchard, Bruno Hurault de Ligny, Olivier Toupance, Hervé Watier, Yvon Lebranchu, and Gilles Paintaud PMCID: PMC2291273 IMPDH activity in thiopurine-treated patients with inflammatory bowel disease – relation to TPMT activity and metabolite concentrations Sofie Haglund, Jan Taipalensuu, Curt Peterson, and Sven Almer PMCID: PMC2291267 No significant effect of SLCO1B1 polymorphism on the pharmacokinetics of rosiglitazone and pioglitazone Annikka Kalliokoski, Mikko Neuvonen, Pertti J Neuvonen, and Mikko Niemi PMCID: PMC2291278 Drug Interactions Time-dependent inhibition of human drug metabolizing cytochromes P450 by tricyclic antidepressants Thomas M Polasek and John O Miners PMCID: PMC2291266 Interaction between midazolam and clarithromycin in the elderly Sara K Quinney, Barbara D Haehner, Melissa B Rhoades, Zhen Lin, J Christopher Gorski, and Stephen D Hall PMCID: PMC2291277 Drug Safety Exposure–response analysis reveals that clinically important toxicity difference can exist between bioequivalent carbamazepine tablets Laszlo Tothfalusi, Szilvia Speidl, and Laszlo Endrenyi PMCID: PMC2291269 Issues concerning the use of hormone replacement therapy and risk of fracture: a population-based, nested case-control study Giovanni Corrao, Antonella Zambon, Federica Nicotra, Valentino Conti, Rossella E Nappi, and Luca Merlino PMCID: PMC2291264 Short Reports Relationship between polypharmacy and underprescribing Mascha A J Kuijpers, Rob J van Marum, Antoine C G Egberts, and Paul A F Jansen PMCID: PMC2291281 The CYP2D6 polymorphism in relation to the metabolism of amitriptyline and nortriptyline in the Faroese population Jónrit Halling, Pál Weihe, and Kim Brosen PMCID: PMC2291274 A comparison of serum antivenom concentrations after intravenous and intramuscular administration of redback (widow) spider antivenom Geoffrey K Isbister, Margaret O'Leary, Mark Miller, Simon G A Brown, Sharmaine Ramasamy, Rosemary James, and Jennifer S Schneider PMCID: PMC2291270 Letters to the Editors Drug–drug interactions – a preventable patient safety issue? Johanna Strandell, Andrew Bate, Marie Lindquist, and I Ralph Edwards PMCID: PMC2291271 Statins and phenytoin interact – a case history Kit Mun Tan, John G Kelly, and Kathleen McGarry PMCID: PMC2291279 Neutropenia induced in a patient by treatment with ritodrine: in vitro evaluation of myeloid progenitor colony-forming cells Kiyomi Tsukimori, Seiichi Morokuma, Takazumi Yoshimura, Koichiro Muta, and Norio Wake PMCID: PMC2291272 |
