Induction of double-strand breaks by S1 nuclease, mung bean nuclease and nuclease P1 in DNA containing abasic sites and nicks.

Strategic down-regulation of DNA polymerase beta by antisense RNA sensitizes mammalian cells to specific DNA damaging agents.

Efficient gene activation in mammalian cells by using recombinant adenovirus expressing site-specific Cre recombinase.

Cell cycle regulation of cdc25C transcription is mediated by the periodic repression of the glutamine-rich activators NF-Y and Sp1.

The high stability of the triple helices formed between short purine oligonucleotides and SIV/HIV-2 vpx genes is determined by the targeted DNA structure.

Promoter recognition in archaea is mediated by transcription factors: identification of transcription factor aTFB from Methanococcus thermolithotrophicus as archaeal TATA-binding protein.

Fine-mapping of shotgun template-libraries; an efficient strategy for the systematic sequencing of genomic DNA.

Hairpins in a DNA site for topoisomerase II studied by 1H- and 31P-NMR.

A human NDP-kinase B specifically binds single-stranded poly-pyrimidine sequences.

TFE3 contains two activation domains, one acidic and the other proline-rich, that synergistically activate transcription.

Hairpin opening by single-strand-specific nucleases.

Microsatellite variation in North American populations of Drosophila melanogaster.

Inhibition of NF-kappa B-Rel A expression by antisense oligodeoxynucleotides suppresses synthesis of urokinase-type plasminogen activator (uPA) but not its inhibitor PAI-1.

Cleavage of double-stranded DNA by 'metalloporphyrin-linker-oligonucleotide' molecules: influence of the linker.

The orientation of binding of human immunodeficiency virus reverse transcriptase on nucleic acid hybrids.

Distinct requirements for primary sequence in the 5'- and 3'-part of a bulge in the hepatitis B virus RNA encapsidation signal revealed by a combined in vivo selection/in vitro amplification system.

Effects of site-specific substitution of 5-fluorouridine on the stabilities of duplex DNA and RNA.

In vitro activity of minimised hammerhead ribozymes.

A comparison of the in vitro activity of DNA-armed and all-RNA hammerhead ribozymes.

Mutational analysis of the att DNA-binding domain of phage Mu transposase.

Mutation detection using immobilized mismatch binding protein (MutS).

Phosphoryl migration during the chemical synthesis of RNA.

Photooxidation of d(TpG) by riboflavin and methylene blue. Isolation and characterization of thymidylyl-(3',5')-2-amino-5-[(2-deoxy-beta-D- erythro-pentofuranosyl)amino]-4H-imidazol-4-one and its primary decomposition product thymidylyl-(3',5')-2,2-diamino-4-[(2-deoxy-beta-D- erythro-pentofuranosyl)amino]-5(2H)-oxazolone.

The effects of sequence context on base dynamics at TpA steps in DNA studied by NMR.

Structural basis for the RNA binding selectivity of oligonucleotide analogues containing alkylsulfide internucleoside linkages and 2'-substituted 3'-deoxyribonucleosides.

The ribonuclease activity of nucleolar protein B23.

Sequences 5' of the first upstream open reading frame in GCN4 mRNA are required for efficient translational reinitiation.

Synthesis and biological activities of a phosphorodithioate analog of 2',5'-oligoadenylate.

Large scale isolation of expression vector cassette by magnetic triple helix affinity capture.

Rapid DNA preparation for 2D gel analysis of replication intermediates.

Protection of megabase DNA from shearing.

Hydroxyquinoline overcomes PCR inhibition by UV-damaged mineral oil.

A lacZ-hygromycin fusion gene and its use in a gene trap vector for marking embryonic stem cells.

Construction of specific cosmids from YACs by homologous recombination in yeast.

Identification of a differentially-expressed message associated with colon cancer liver metastasis using an improved method of differential display.

Functional expression of a single-chain anti-progesterone antibody fragment in the cytoplasm of a mutant Escherichia coli.

Insertion of unique sites into YAC arms for rapid physical analysis following YAC transfer into mammalian cells.

A rapid procedure for the compositional analysis of yeast artificial chromosomes.