| | This journal provides immediate access to some articles. Commentaries War and early state formation in Oaxaca, Mexico Charles S. Spencer PMCID: PMC208728 Chromosome rearrangements in evolution: From gene order to genome sequence and back David Sankoff and Joseph H. Nadeau PMCID: PMC208729 The first candidate gene for dyslexia: Turning the page of a new chapter of research Elena L. Grigorenko PMCID: PMC208730 Copper, β-amyloid, and Alzheimer's disease: Tapping a sensitive connection Ashley I. Bush, Colin L. Masters, and Rudolph E. Tanzi PMCID: PMC208731 Caging helps proteins fold D. Thirumalai, Dmitri K. Klimov, and George H. Lorimer PMCID: PMC208732 Insulin's expanding control of forkheads Michael P. Czech PMCID: PMC208733 Perspective Calcification in atherosclerosis: Bone biology and chronic inflammation at the arterial crossroads Terence M. Doherty, Kamlesh Asotra, Lorraine A. Fitzpatrick, Jian-Hua Qiao, Douglas J. Wilkin, Robert C. Detrano, Colin R. Dunstan, Prediman K. Shah, and Tripathi B. Rajavashisth PMCID: PMC208734 The discovery of the α-helix and β-sheet, the principal structural features of proteins David Eisenberg PMCID: PMC208735 Physical Sciences Applied Mathematics Scaling and universality in continuous length combinatorial optimization David Aldous and Allon G. Percus PMCID: PMC208736 Shock-wave cosmology inside a black hole Joel Smoller and Blake Temple PMCID: PMC208737 Astronomy Shock-wave cosmology inside a black hole Joel Smoller and Blake Temple PMCID: PMC208737 Chemistry Ultrasensitive two-color fluorescence probes for dipole potential in phospholipid membranes Andrey S. Klymchenko, Guy Duportail, Yves Mély, and Alexander P. Demchenko PMCID: PMC208738 A model for the cooperative free energy transduction and kinetics of ATP hydrolysis by F1-ATPase Yi Qin Gao, Wei Yang, Rudolph A. Marcus, and Martin Karplus PMCID: PMC208758 Geophysics Observations of a “weekend effect” in diurnal temperature range Piers M. de F. Forster and Susan Solomon PMCID: PMC208739 Biological Sciences Anthropology An early modern human from the Peştera cu Oase, Romania Erik Trinkaus, Oana Moldovan, ştefan Milota, Adrian Bîlgăr, Laurenţiu Sarcina, Sheela Athreya, Shara E. Bailey, Ricardo Rodrigo, Gherase Mircea, Thomas Higham, Christopher Bronk Ramsey, and Johannes van der Plicht PMCID: PMC208740 Applied Biological Sciences Probe selection for high-density oligonucleotide arrays Rui Mei, Earl Hubbell, Stefan Bekiranov, Mike Mittmann, Fred C. Christians, Mei-Mei Shen, Gang Lu, Joy Fang, Wei-Min Liu, Tom Ryder, Paul Kaplan, David Kulp, and Teresa A. Webster PMCID: PMC208741 Biochemistry Swapping single-stranded DNA sequence specificities of relaxases from conjugative plasmids F and R100 Matthew J. Harley and Joel F. Schildbach PMCID: PMC208742 Inorganic polyphosphate stimulates mammalian TOR, a kinase involved in the proliferation of mammary cancer cells Lihong Wang, Cresson D. Fraley, Jesika Faridi, Arthur Kornberg, and Richard A. Roth PMCID: PMC208743 Computational design of a Zn2+ receptor that controls bacterial gene expression M. A. Dwyer, L. L. Looger, and H. W. Hellinga PMCID: PMC208744 NMR structure of the forkhead-associated domain from the Arabidopsis receptor kinase-associated protein phosphatase Gui-in Lee, Zhaofeng Ding, John C. Walker, and Steven R. Van Doren PMCID: PMC208745 Redirecting tyrosine kinase signaling to an apoptotic caspase pathway through chimeric adaptor proteins Perry L. Howard, Marie C. Chia, Suzanne Del Rizzo, Fei-Fei Liu, and Tony Pawson PMCID: PMC208746 Helix-stabilized cyclic peptides as selective inhibitors of steroid receptor–coactivator interactions Anne-Marie Leduc, John O. Trent, James L. Wittliff, Kelli S. Bramlett, Stephen L. Briggs, Nikolay Y. Chirgadze, Yong Wang, Thomas P. Burris, and Arno F. Spatola PMCID: PMC208747 Hydrolysis of RNA/DNA hybrids containing nonpolar pyrimidine isosteres defines regions essential for HIV type 1 polypurine tract selection Jason W. Rausch, Jin Qu, Hye Young Yi-Brunozzi, Eric T. Kool, and Stuart F. J. Le Grice PMCID: PMC208748 Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation Hitomi Matsuzaki, Hiroaki Daitoku, Mitsutoki Hatta, Keiji Tanaka, and Akiyoshi Fukamizu PMCID: PMC208749 Poxvirus DNA topoisomerase knockout mutant exhibits decreased infectivity associated with reduced early transcription Flavio Da Fonseca and Bernard Moss PMCID: PMC208750 A noncognate aminoacyl-tRNA synthetase that may resolve a missing link in protein evolution Stéphane Skouloubris, Lluís Ribas de Pouplana, Hilde de Reuse, and Tamara L. Hendrickson PMCID: PMC208751 Measurements of nitric oxide on the heme iron and β-93 thiol of human hemoglobin during cycles of oxygenation and deoxygenation Xiuli Xu, Man Cho, Netanya Y. Spencer, Neil Patel, Zhi Huang, Howard Shields, S. Bruce King, Mark T. Gladwin, Neil Hogg, and Daniel B. Kim-Shapiro PMCID: PMC208752 Electron microscopic evidence for nucleation and growth of 3D acetylcholine receptor microcrystals in structured lipid–detergent matrices Yoav Paas, Jean Cartaud, Michel Recouvreur, Regis Grailhe, Virginie Dufresne, Eva Pebay-Peyroula, Ehud M. Landau, and Jean-Pierre Changeux PMCID: PMC208753 Redefining cholesterol's role in the mechanism of the cholesterol-dependent cytolysins Kara S. Giddings, Arthur E. Johnson, and Rodney K. Tweten PMCID: PMC208754 Modification by docosahexaenoic acid of age-induced alterations in gene expression and molecular composition of rat brain phospholipids Gwendolyn Barceló-Coblijn, Endre Hőgyes, Klára Kitajka, László G. Puskás, Ágnes Zvara, László Hackler, Jr., Csaba Nyakas, Zsuzsa Penke, and Tibor Farkas PMCID: PMC208755 Exon junction complexes mediate the enhancing effect of splicing on mRNA expression Heather L. Wiegand, Shihua Lu, and Bryan R. Cullen PMCID: PMC208756 Biophysics Ultrasensitive two-color fluorescence probes for dipole potential in phospholipid membranes Andrey S. Klymchenko, Guy Duportail, Yves Mély, and Alexander P. Demchenko PMCID: PMC208738 INAUGURAL ARTICLE by a Recently Elected Academy Member: Direct observation of dipolar couplings between distant protons in weakly aligned nucleic acids Jérôme Boisbouvier, Frank Delaglio, and Ad Bax PMCID: PMC208757 A model for the cooperative free energy transduction and kinetics of ATP hydrolysis by F1-ATPase Yi Qin Gao, Wei Yang, Rudolph A. Marcus, and Martin Karplus PMCID: PMC208758 Role of residual structure in the unfolded state of a thermophilic protein Srebrenka Robic, Mercedes Guzman-Casado, Jose M. Sanchez-Ruiz, and Susan Marqusee PMCID: PMC208759 Single metallic nanoparticle imaging for protein detection in cells L. Cognet, C. Tardin, D. Boyer, D. Choquet, P. Tamarat, and B. Lounis PMCID: PMC208760 A force-based protein biochip K. Blank, T. Mai, I. Gilbert, S. Schiffmann, J. Rankl, R. Zivin, C. Tackney, T. Nicolaus, K. Spinnler, F. Oesterhelt, M. Benoit, H. Clausen-Schaumann, and H. E. Gaub PMCID: PMC208761 Using protein design for homology detection and active site searches Jimin Pei, Nikolay V. Dokholyan, Eugene I. Shakhnovich, and Nick V. Grishin PMCID: PMC208762 From the Cover:
How protein thermodynamics and folding mechanisms are altered by the chaperonin cage: Molecular simulations Fumiko Takagi, Nobuyasu Koga, and Shoji Takada PMCID: PMC208763 Supercoiling and denaturation in Gal repressor/heat unstable nucleoid protein (HU)-mediated DNA looping Giuseppe Lia, David Bensimon, Vincent Croquette, Jean-Francois Allemand, David Dunlap, Dale E. A. Lewis, Sankar Adhya, and Laura Finzi PMCID: PMC208764 Beyond the conventional description of dynamic force spectroscopy of adhesion bonds O. K. Dudko, A. E. Filippov, J. Klafter, and M. Urbakh PMCID: PMC208765 Competing ligands stabilize alternate conformations of the energy coupling motif of a TonB-dependent outer membrane transporter Gail E. Fanucci, Nathalie Cadieux, Robert J. Kadner, and David S. Cafiso PMCID: PMC208766 Gating and regulation of connexin 43 (Cx43) hemichannels Jorge E. Contreras, Juan C. Sáez, Feliksas F. Bukauskas, and Michael V. L. Bennett PMCID: PMC208767 Cell Biology Conserved pathways within bacteria and yeast as revealed by global protein network alignment Brian P. Kelley, Roded Sharan, Richard M. Karp, Taylor Sittler, David E. Root, Brent R. Stockwell, and Trey Ideker PMCID: PMC208768 Dissecting the roles of β-catenin and cyclin D1 during mammary development and neoplasia Tracey M. Rowlands, Irina V. Pechenkina, Sarah J. Hatsell, Richard G. Pestell, and Pamela Cowin PMCID: PMC208769 β-Arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors Mounia Azzi, Pascale G. Charest, Stéphane Angers, Guy Rousseau, Trudy Kohout, Michel Bouvier, and Graciela Piñeyro PMCID: PMC208770 Measuring stem cell frequency in epidermis: A quantitative in vivo functional assay for long-term repopulating cells T. E. Schneider, C. Barland, A. M. Alex, M. L. Mancianti, Y. Lu, J. E. Cleaver, H. J. Lawrence, and R. Ghadially PMCID: PMC208771 Natural variation in nucleolar dominance reveals the relationship between nucleolus organizer chromatin topology and rRNA gene transcription in Arabidopsis Olga Pontes, Richard J. Lawrence, Nuno Neves, Manuela Silva, Jae-Hyeok Lee, Z. Jeffrey Chen, Wanda Viegas, and Craig S. Pikaard PMCID: PMC208772 Mitochondrial positioning in fission yeast is driven by association with dynamic microtubules and mitotic spindle poles Michael P. Yaffe, Nico Stuurman, and Ronald D. Vale PMCID: PMC208773 Widespread cytoplasmic mRNA transport in yeast: Identification of 22 bud-localized transcripts using DNA microarray analysis K. A. Shepard, A. P. Gerber, A. Jambhekar, P. A. Takizawa, P. O. Brown, D. Herschlag, J. L. DeRisi, and R. D. Vale PMCID: PMC208774 Antiangiogenic proteins require plasma fibronectin or vitronectin for in vivo activity Ming Yi, Takao Sakai, Reinhard Fässler, and Erkki Ruoslahti PMCID: PMC208775 Human cytomegalovirus UL83-coded pp65 virion protein inhibits antiviral gene expression in infected cells Edward P. Browne and Thomas Shenk PMCID: PMC208776 Two CD95 tumor classes with different sensitivities to antitumor drugs Alicia Algeciras-Schimnich, Eric M. Pietras, Bryan C. Barnhart, Patrick Legembre, Shrijay Vijayan, Susan L. Holbeck, and Marcus E. Peter PMCID: PMC208777 Developmental Biology Combinatorial interactions of Serpent, Lozenge, and U-shaped regulate crystal cell lineage commitment during Drosophila hematopoiesis Nancy Fossett, Kristy Hyman, Kathleen Gajewski, Stuart H. Orkin, and Robert A. Schulz PMCID: PMC208778 Embryonic stem cells can form germ cells in vitro Yayoi Toyooka, Naoki Tsunekawa, Ryuko Akasu, and Toshiaki Noce PMCID: PMC208779 Drosophila screening model for metastasis: Semaphorin 5c is required for l(2)gl cancer phenotype Elisa C. Woodhouse, Amy Fisher, Russell W. Bandle, Bianca Bryant-Greenwood, Lula Charboneau, Emanuel F. Petricoin, III, and Lance A. Liotta PMCID: PMC208780 Evolutionary origins of the vertebrate heart: Specification of the cardiac lineage in Ciona intestinalis Brad Davidson and Michael Levine PMCID: PMC208781 Ecology Global climate change and mammalian species diversity in U.S. national parks Catherine E. Burns, Kevin M. Johnston, and Oswald J. Schmitz PMCID: PMC208782 Seasonality, density dependence, and population cycles in Hokkaido voles Nils Chr. Stenseth, Hildegunn Viljugrein, Takashi Saitoh, Thomas F. Hansen, Marte O. Kittilsen, Erik Bølviken, and Fredrik Glöckner PMCID: PMC208783 Evolution Evolution's cauldron: Duplication, deletion, and rearrangement in the mouse and human genomes W. James Kent, Robert Baertsch, Angie Hinrichs, Webb Miller, and David Haussler PMCID: PMC208784 Fruit odor discrimination and sympatric host race formation in Rhagoletis Charles Linn, Jr., Jeffrey L. Feder, Satoshi Nojima, Hattie R. Dambroski, Stewart H. Berlocher, and Wendell Roelofs PMCID: PMC208785 The evolution of early Foraminifera Jan Pawlowski, Maria Holzmann, Cédric Berney, José Fahrni, Andrew J. Gooday, Tomas Cedhagen, Andrea Habura, and Samuel S. Bowser PMCID: PMC208786 Compensatory evolution of a precursor messenger RNA secondary structure in the Drosophila melanogaster Adh gene Ying Chen and Wolfgang Stephan PMCID: PMC208787 Genetics A nonconserved Ala401 in the yeast Rsp5 ubiquitin ligase is involved in degradation of Gap1 permease and stress-induced abnormal proteins Chikara Hoshikawa, Mika Shichiri, Shigeru Nakamori, and Hiroshi Takagi PMCID: PMC208788 Mathematical models of RNA silencing: Unidirectional amplification limits accidental self-directed reactions Carl T. Bergstrom, Erin McKittrick, and Rustom Antia PMCID: PMC208789 The BCSC-1 locus at chromosome 11q23-q24 is a candidate tumor suppressor gene Eric S. Martin, Rossano Cesari, Francesca Pentimalli, Kristine Yoder, Richard Fishel, Andrew L. Himelstein, S. Eric Martin, Andrew K. Godwin, Massimo Negrini, and Carlo M. Croce PMCID: PMC208790 CCAAT-binding factor regulates expression of the β1 subunit of soluble guanylyl cyclase gene in the BE2 human neuroblastoma cell line Iraida G. Sharina, Emil Martin, Anthony Thomas, Karen L. Uray, and Ferid Murad PMCID: PMC208791 A genomewide screen in Saccharomyces cerevisiae for genes that suppress the accumulation of mutations Meng-Er Huang, Anne-Gaëlle Rio, Alain Nicolas, and Richard D. Kolodner PMCID: PMC208792 ASH1, a Drosophila trithorax group protein, is required for methylation of lysine 4 residues on histone H3 Kristin Nastase Byrd and Allen Shearn PMCID: PMC208793 Maize-targeted mutagenesis: A knockout resource for maize Bruce P. May, Hong Liu, Erik Vollbrecht, Lynn Senior, Pablo D. Rabinowicz, Donna Roh, Xiaokang Pan, Lincoln Stein, Mike Freeling, Danny Alexander, and Rob Martienssen PMCID: PMC208794 The presence of p53 mutations in human osteosarcomas correlates with high levels of genomic instability Michael Overholtzer, Pulivarthi H. Rao, Reyna Favis, Xin-Yan Lu, Michael B. Elowitz, Francis Barany, Marc Ladanyi, Richard Gorlick, and Arnold J. Levine PMCID: PMC208795 From the Cover:
A candidate gene for developmental dyslexia encodes a nuclear tetratricopeptide repeat domain protein dynamically regulated in brain Mikko Taipale, Nina Kaminen, Jaana Nopola-Hemmi, Tuomas Haltia, Birgitta Myllyluoma, Heikki Lyytinen, Kurt Muller, Minna Kaaranen, Perttu J. Lindsberg, Katariina Hannula-Jouppi, and Juha Kere PMCID: PMC208796 Single-nucleotide polymorphism genotyping on optical thin-film biosensor chips Xiao-bo Zhong, Robert Reynolds, Judith R. Kidd, Kenneth K. Kidd, Robert Jenison, Richard A. Marlar, and David C. Ward PMCID: PMC208797 Immunology Negative selection imparts peptide specificity to the mature T cell repertoire Eric S. Huseby, Frances Crawford, Janice White, John Kappler, and Philippa Marrack PMCID: PMC208798 Variable hematopoietic graft rejection and graft-versus-host disease in MHC-matched strains of mice Thai M. Cao, Betty Lo, Erik A. Ranheim, F. Carl Grumet, and Judith A. Shizuru PMCID: PMC208799 Antigen receptor loci poised for V(D)J rearrangement are broadly associated with BRG1 and flanked by peaks of histone H3 dimethylated at lysine 4 Katrina B. Morshead, David N. Ciccone, Sean D. Taverna, C. David Allis, and Marjorie A. Oettinger PMCID: PMC208800 Interference with T cell receptor–HLA-DR interactions by Epstein–Barr virus gp42 results in reduced T helper cell recognition Maaike E. Ressing, Daphne van Leeuwen, Frank A. W. Verreck, Raquel Gomez, Bianca Heemskerk, Mireille Toebes, Maureen M. Mullen, Theodore S. Jardetzky, Richard Longnecker, Marco W. Schilham, Tom H. M. Ottenhoff, Jacques Neefjes, Ton N. Schumacher, Lindsey M. Hutt-Fletcher, and Emmanuel J. H. J. Wiertz PMCID: PMC208801 Expression of the type 2 receptor for cysteinyl leukotrienes (CysLT2R) by human mast cells: Functional distinction from CysLT1R Elizabeth A. Mellor, Nita Frank, Dulce Soler, Martin R. Hodge, Jose M. Lora, K. Frank Austen, and Joshua A. Boyce PMCID: PMC208802 A natural mutation in the Tyk2 pseudokinase domain underlies altered susceptibility of B10.Q/J mice to infection and autoimmunity Michael H. Shaw, Victor Boyartchuk, Sandy Wong, Marina Karaghiosoff, Josiane Ragimbeau, Sandra Pellegrini, Mathias Muller, William F. Dietrich, and George S. Yap PMCID: PMC208803 Medical Sciences INAUGURAL ARTICLE by a Recently Elected Academy Member: Low monoamine oxidase B in peripheral organs in smokers Joanna S. Fowler, Jean Logan, Gene-Jack Wang, Nora D. Volkow, Frank Telang, Wei Zhu, Dinko Franceschi, Naomi Pappas, Richard Ferrieri, Colleen Shea, Victor Garza, Youwen Xu, David Schlyer, S. John Gatley, Yu-Shin Ding, David Alexoff, Donald Warner, Noelwah Netusil, Pauline Carter, Millard Jayne, Payton King, and Paul Vaska PMCID: PMC208804 EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells Celina G. Kleer, Qi Cao, Sooryanarayana Varambally, Ronglai Shen, Ichiro Ota, Scott A. Tomlins, Debashis Ghosh, Richard G. A. B. Sewalt, Arie P. Otte, Daniel F. Hayes, Michael S. Sabel, Donna Livant, Stephen J. Weiss, Mark A. Rubin, and Arul M. Chinnaiyan PMCID: PMC208805 Erythropoietin reduces myocardial infarction and left ventricular functional decline after coronary artery ligation in rats Chanil Moon, Melissa Krawczyk, Dongchoon Ahn, Ismayil Ahmet, Doojin Paik, Edward G. Lakatta, and Mark I. Talan PMCID: PMC208806 Tumor necrosis factor α-converting enzyme mediates MUC5AC mucin expression in cultured human airway epithelial cells Matt X. G. Shao, Iris F. Ueki, and Jay A. Nadel PMCID: PMC208807 From the Cover:
Insulin regulates the activity of forkhead transcription factor Hnf-3β/Foxa-2 by Akt-mediated phosphorylation and nuclear/cytosolic localization Christian Wolfrum, Daniel Besser, Edlira Luca, and Markus Stoffel PMCID: PMC208808 IL-3 receptor signaling is dispensable for BCR-ABL-induced myeloproliferative disease Stephane Wong, Jami McLaughlin, Donghui Cheng, Kevin Shannon, Lorraine Robb, and Owen N. Witte PMCID: PMC208809 Antisense therapy targeting MDM2 oncogene in prostate cancer: Effects on proliferation, apoptosis, multiple gene expression, and chemotherapy Zhuo Zhang, Mao Li, Hui Wang, Sudhir Agrawal, and Ruiwen Zhang PMCID: PMC208810 An enzootic transmission cycle of Lyme borreliosis spirochetes in the southeastern United States J. H. Oliver, Jr., T. Lin, L. Gao, K. L. Clark, C. W. Banks, L. A. Durden, A. M. James, and F. W. Chandler, Jr. PMCID: PMC208811 The p7 polypeptide of hepatitis C virus is critical for infectivity and contains functionally important genotype-specific sequences Akito Sakai, Marisa St. Claire, Kristina Faulk, Sugantha Govindarajan, Suzanne U. Emerson, Robert H. Purcell, and Jens Bukh PMCID: PMC208812 Microbiology INAUGURAL ARTICLE by a Recently Elected Academy Member: Hepatocyte turnover during resolution of a transient hepadnaviral infection Jesse Summers, Allison R. Jilbert, Wengang Yang, Carol E. Aldrich, Jeffry Saputelli, Samuel Litwin, Eugene Toll, and William S. Mason PMCID: PMC208813 The complete genome sequence of Chromobacterium violaceum reveals remarkable and exploitable bacterial adaptability PMCID: PMC208814 A quantitative, highly sensitive cell-based infectivity assay for mouse scrapie prions P.-C. Klöhn, L. Stoltze, E. Flechsig, M. Enari, and C. Weissmann PMCID: PMC208815 Inhibition of HIV infectivity by a natural human isolate of Lactobacillus jensenii engineered to express functional two-domain CD4 Theresa L.-Y. Chang, Chia-Hwa Chang, David A. Simpson, Qiang Xu, Patrick K. Martin, Laurel A. Lagenaur, Gary K. Schoolnik, David D. Ho, Sharon L. Hillier, Mark Holodniy, John A. Lewicki, and Peter P. Lee PMCID: PMC208816 Functional characterization of a portion of the Moloney murine leukemia virus gag gene by genetic footprinting Marcy R. Auerbach, Chang Shu, Artem Kaplan, and Ila R. Singh PMCID: PMC208817 Borrelia oxidative stress response regulator, BosR: A distinctive Zn-dependent transcriptional activator Julie A. Boylan, James E. Posey, and Frank C. Gherardini PMCID: PMC208818 Complete genome sequence and analysis of Wolinella succinogenes Claudia Baar, Mark Eppinger, Guenter Raddatz, Jörg Simon, Christa Lanz, Oliver Klimmek, Ramkumar Nandakumar, Roland Gross, Andrea Rosinus, Heike Keller, Pratik Jagtap, Burkhard Linke, Folker Meyer, Hermann Lederer, and Stephan C. Schuster PMCID: PMC208819 Neuroscience Chronic stress and obesity: A new view of “comfort food” Mary F. Dallman, Norman Pecoraro, Susan F. Akana, Susanne E. la Fleur, Francisca Gomez, Hani Houshyar, M. E. Bell, Seema Bhatnagar, Kevin D. Laugero, and Sotara Manalo PMCID: PMC208820 Sounds and silence: An optical topography study of language recognition at birth Marcela Peña, Atsushi Maki, Damir Kova  ić, Ghislaine Dehaene-Lambertz, Hideaki Koizumi, Furio Bouquet, and Jacques Mehler PMCID: PMC208821 Genetically engineered mice with an additional class of cone photoreceptors: Implications for the evolution of color vision Philip M. Smallwood, Bence P. Ölveczky, Gary L. Williams, Gerald H. Jacobs, Benjamin E. Reese, Markus Meister, and Jeremy Nathans PMCID: PMC208822 Akt as a mediator of cell death Hongbo R. Luo, Hidenori Hattori, Mir Ahamed Hossain, Lynda Hester, Yunfei Huang, Whaseon Lee-Kwon, Mark Donowitz, Eiichiro Nagata, and Solomon H. Snyder PMCID: PMC208823 A1 adenosine receptors mediate hypoxia-induced ventriculomegaly Christopher P. Turner, Meltem Seli, Laura Ment, William Stewart, Henglin Yan, Björn Johansson, Bertil B. Fredholm, Michael Blackburn, and Scott A. Rivkees PMCID: PMC208824 Cytosol-endoplasmic reticulum interplay by Sec61α translocon in polyglutamine-mediated neurotoxicity in Drosophila Hirotaka Kanuka, Erina Kuranaga, Tetsuo Hiratou, Tatsushi Igaki, Bryce Nelson, Hideyuki Okano, and Masayuki Miura PMCID: PMC208825 Activation of ATP-sensitive K+ (KATP) channels by H2O2 underlies glutamate-dependent inhibition of striatal dopamine release Marat V. Avshalumov and Margaret E. Rice PMCID: PMC208826 Exclusively targeting β-secretase to lipid rafts by GPI-anchor addition up-regulates β-site processing of the amyloid precursor protein Joanna M. Cordy, Ishrut Hussain, Colin Dingwall, Nigel M. Hooper, and Anthony J. Turner PMCID: PMC208827 Quinol-based cyclic antioxidant mechanism in estrogen neuroprotection Laszlo Prokai, Katalin Prokai-Tatrai, Pal Perjesi, Alevtina D. Zharikova, Evelyn J. Perez, Ran Liu, and James W. Simpkins PMCID: PMC208828 Physiology Molecular cloning and spatio-temporal expression of the prostaglandin transporter: A basis for the action of prostaglandins in the bovine reproductive system Sakhila K. Banu, Joe A. Arosh, Pierre Chapdelaine, and Michel A. Fortier PMCID: PMC208829 A glucose sensor hiding in a family of transporters Ana Díez-Sampedro, Bruce A. Hirayama, Christina Osswald, Valentin Gorboulev, Katharina Baumgarten, Christopher Volk, Ernest M. Wright, and Hermann Koepsell PMCID: PMC208830 Calsequestrin determines the functional size and stability of cardiac intracellular calcium stores: Mechanism for hereditary arrhythmia Dmitry Terentyev, Serge Viatchenko-Karpinski, Inna Györke, Pompeo Volpe, Simon C. Williams, and Sandor Györke PMCID: PMC208831 Plant Biology LAX and SPA: Major regulators of shoot branching in rice Keishi Komatsu, Masahiko Maekawa, Shin Ujiie, Yuzuki Satake, Ikuyo Furutani, Hironobu Okamoto, Ko Shimamoto, and Junko Kyozuka PMCID: PMC208832 A novel domain in the protein kinase SOS2 mediates interaction with the protein phosphatase 2C ABI2 Masaru Ohta, Yan Guo, Ursula Halfter, and Jian-Kang Zhu PMCID: PMC208833 HSP90 interacts with RAR1 and SGT1 and is essential for RPS2-mediated disease resistance in Arabidopsis Akira Takahashi, Catarina Casais, Kazuya Ichimura, and Ken Shirasu PMCID: PMC208834 From the Cover:
Cell wall arabinan is essential for guard cell function Louise Jones, Jennifer L. Milne, David Ashford, and Simon J. McQueen-Mason PMCID: PMC208835 Reactive oxygen species and ethylene play a positive role in lateral root base nodulation of a semiaquatic legume Wim D'Haeze, Riet De Rycke, René Mathis, Sofie Goormachtig, Sophie Pagnotta, Christa Verplancke, Ward Capoen, and Marcelle Holsters PMCID: PMC208836 Blue light regulates an auxin-induced K+-channel gene in the maize coleoptile I. Fuchs, K. Philippar, K. Ljung, G. Sandberg, and R. Hedrich PMCID: PMC208837 Psychology Newborn infants can organize the auditory world István Winkler, Elena Kushnerenko, János Horváth, Rita Čeponienė, Vineta Fellman, Minna Huotilainen, Risto Näätänen, and Elyse Sussman PMCID: PMC208846 Social Sciences Anthropology An early modern human from the Peştera cu Oase, Romania Erik Trinkaus, Oana Moldovan, ştefan Milota, Adrian Bîlgăr, Laurenţiu Sarcina, Sheela Athreya, Shara E. Bailey, Ricardo Rodrigo, Gherase Mircea, Thomas Higham, Christopher Bronk Ramsey, and Johannes van der Plicht PMCID: PMC208740 The origin of war: New 14C dates from ancient Mexico Kent V. Flannery and Joyce Marcus PMCID: PMC208841 Psychology From the Cover:
Dynamics of feature binding during object-selective attention M. A. Schoenfeld, C. Tempelmann, A. Martinez, J.-M. Hopf, C. Sattler, H.-J. Heinze, and S. A. Hillyard PMCID: PMC208844 Newborn infants can organize the auditory world István Winkler, Elena Kushnerenko, János Horváth, Rita Čeponienė, Vineta Fellman, Minna Huotilainen, Risto Näätänen, and Elyse Sussman PMCID: PMC208846 Corrections Editorial Expression of Concern: Preferential repair of ionizing radiation-induced damage in the transcribed strand of an active human gene is defective in Cockayne syndrome Nicholas R. Cozzarelli PMCID: PMC208848 Corrects: S A Leadon, et al. Preferential repair of ionizing radiation-induced damage in the transcribed strand of an active human gene is defective in Cockayne syndrome. Proc Natl Acad Sci U S A. 1993 November 15; 90(22): 10499–10503. Proc Natl Acad Sci U S A. 2003 September 30; 100(20): 11816. Published online 2003 September 18. doi: 10.1073/pnas.2135351100.PMCID: PMC208849 Corrects: D. Larry Sparks, et al. Trace amounts of copper in water induce β-amyloid plaques and learning deficits in a rabbit model of Alzheimer's disease. Proc Natl Acad Sci U S A. 2003 September 16; 100(19): 11065–11069. Proc Natl Acad Sci U S A. 2003 September 30; 100(20): 11816. Published online 2003 September 16. doi: 10.1073/pnas.2034612100.PMCID: PMC208850 Corrects: M. B. Dickman, et al. Abrogation of disease development in plants expressing animal
antiapoptotic genes. Proc Natl Acad Sci U S A. 2001 June 5; 98(12): 6957–6962. |
