pmc logo imageJournal ListSearchpmc logo image
Logo of pnasPNAS Home page.PNAS Editorial BoardPNAS AboutPNAS SubscriptionsPNAS Info for Authors
This journal provides immediate access to some articles.
Other Issues:  previous | next | latest | archive
Volume 94(6);  March 18, 1997
Commentaries
The Alzheimer family of diseases: Many etiologies, one pathogenesis?
John Hardy
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2095–2097.
PMCID: PMC33655
Pax-6: Where to be conserved is not conservative
William A. Harris
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2098–2100.
PMCID: PMC33656
Bronchial asthma: Lessons from murine models
G. J. Gleich and H. Kita
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2101–2102.
PMCID: PMC33657
Altered DNA methylation and genome instability: A new pathway to cancer?
Peter A. Jones and Mark L. Gonzalgo
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2103–2105.
PMCID: PMC33658
Perspective
The objects of selection
Ernst Mayr
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2091–2094.
PMCID: PMC33654
Physical Sciences
Chemistry
Virtual combinatorial libraries: Dynamic generation of molecular and supramolecular diversity by self-assembly
Ivan Huc and Jean-Marie Lehn
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2106–2110.
PMCID: PMC20048
Biological Sciences
Agricultural Sciences
Transgenic elite indica rice plants expressing CryIAc [partial differential]-endotoxin of Bacillus thuringiensis are resistant against yellow stem borer (Scirpophaga incertulas)
Pritilata Nayak, Debabrata Basu, Sampa Das, Asitava Basu, Dipankar Ghosh, Neeliyath A. Ramakrishnan, Maloy Ghosh, and Soumitra K. Sen
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2111–2116.
PMCID: PMC20049
Applied Biological Sciences
Selection of marker-free transgenic plants using the isopentenyl transferase gene
Hiroyasu Ebinuma, Koichi Sugita, Etsuko Matsunaga, and Mikiko Yamakado
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2117–2121.
PMCID: PMC20050
Removal of a cryptic intron and subcellular localization of green fluorescent protein are required to mark transgenic Arabidopsis plants brightly
Jim Haseloff, Kirby R. Siemering, Douglas C. Prasher, and Sarah Hodge
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2122–2127.
PMCID: PMC20051
Generation of cDNA expression libraries enriched for in-frame sequences
Claytus A. Davis and Seymour Benzer
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2128–2132.
PMCID: PMC20052
Biochemistry
Identification of a functional water channel in cytochrome P450 enzymes
Tudor I. Oprea, Gerhard Hummer, and Angel E. García
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2133–2138.
PMCID: PMC20053
Structural features of the binding site for ribosomal protein S8 in Escherichia coli 16S rRNA defined using NMR spectroscopy
K. Kalurachchi, K. Uma, R. A. Zimmermann, and E. P. Nikonowicz
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2139–2144.
PMCID: PMC20054
From phosphatases to vanadium peroxidases: A similar architecture of the active site
Wieger Hemrika, Rokus Renirie, Henk L. Dekker, Phil Barnett, and Ron Wever
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2145–2149.
PMCID: PMC20055
Discovery and analysis of inflammatory disease-related genes using cDNA microarrays
Renu A. Heller, Mark Schena, Andrew Chai, Dari Shalon, Tod Bedilion, James Gilmore, David E. Woolley, and Ronald W. Davis
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2150–2155.
PMCID: PMC20056
The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins
Arnim Pause, Stephen Lee, Robert A. Worrell, David Y. T. Chen, Wilson H. Burgess, W. Marston Linehan, and Richard D. Klausner
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2156–2161.
PMCID: PMC20057
Nucleoprotein-based nanoscale assembly
Steven S. Smith, Luming Niu, David J. Baker, John A. Wendel, Susan E. Kane, and Darrin S. Joy
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2162–2167.
PMCID: PMC20058
Cell cycle-dependent phosphorylation of mammalian protein phosphatase 1 by cdc2 kinase
Young-Guen Kwon, Soo Young Lee, Yongwon Choi, Paul Greengard, and Angus C. Nairn
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2168–2173.
PMCID: PMC20059
Supercoil-induced extrusion of a regulatory DNA hairpin
Xing Dai, Miriam B. Greizerstein, Krisztina Nadas-Chinni, and Lucia B. Rothman-Denes
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2174–2179.
PMCID: PMC20060
Receptor and Gβγ isoform-specific interactions with G protein-coupled receptor kinases
Yehia Daaka, Julie A. Pitcher, Mark Richardson, Robert H. Stoffel, Janet D. Robishaw, and Robert J. Lefkowitz
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2180–2185.
PMCID: PMC20061
Silent information regulator protein complexes in Saccharomyces cerevisiae: A SIR2/SIR4 complex and evidence for a regulatory domain in SIR4 that inhibits its interaction with SIR3
Danesh Moazed, Amy Kistler, Amy Axelrod, Jasper Rine, and Alexander D. Johnson
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2186–2191.
PMCID: PMC20062
Evidence for a lipochaperonin: Association of active proteinfolding GroESL oligomers with lipids can stabilize membranes under heat shock conditions
Zsolt Török, Ibolya Horváth, Pierre Goloubinoff, Eszter Kovács, Attila Glatz, Gábor Balogh, and László Vígh
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2192–2197.
PMCID: PMC20063
Identification of an alternative form of human lactoferrin mRNA that is expressed differentially in normal tissues and tumor-derived cell lines
Paul D. Siebert and Betty C. B. Huang
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2198–2203.
PMCID: PMC20064
A putative angiogenin receptor in angiogenin-responsive human endothelial cells
Guo-fu Hu, James F. Riordan, and Bert L. Vallee
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2204–2209.
PMCID: PMC20065
Volatile signals of the major histocompatibility complex in male mouse urine
Alan G. Singer, Gary K. Beauchamp, and Kunio Yamazaki
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2210–2214.
PMCID: PMC20066
DNA damage can alter the stability of nucleosomes: Effects are dependent on damage type
David B. Mann, David L. Springer, and Michael J. Smerdon
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2215–2220.
PMCID: PMC20067
Regulation of E2F through ubiquitin–proteasome-dependent degradation: Stabilization by the pRB tumor suppressor protein
Miguel R. Campanero and Erik K. Flemington
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2221–2226.
PMCID: PMC20068
Identification of a novel negative retinoic acid responsive element in the promoter of the human matrix Gla protein gene
Jutta Kirfel, Manuela Kelter, Leonor M. Cancela, Paul A. Price, and Roland Schüle
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2227–2232.
PMCID: PMC20069
Coordination dynamics of biological zinc “clusters” in metallothioneins and in the DNA-binding domain of the transcription factor Gal4
Wolfgang Maret, Kjeld S. Larsen, and Bert L. Vallee
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2233–2237.
PMCID: PMC20070
Molecular characterization of human and mouse fatty acid amide hydrolases
Dan K. Giang and Benjamin F. Cravatt
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2238–2242.
PMCID: PMC20071
Sequence requirements of the HIV-1 protease flap region determined by saturation mutagenesis and kinetic analysis of flap mutants
Wei Shao, Lorraine Everitt, Marianne Manchester, Daniel D. Loeb, Clyde A. Hutchison, III, and Ronald Swanstrom
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2243–2248.
PMCID: PMC20072
The La antigen binds 5′ noncoding region of the hepatitis C virus RNA in the context of the initiator AUG codon and stimulates internal ribosome entry site-mediated translation
Naushad Ali and Aleem Siddiqui
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2249–2254.
PMCID: PMC20073
The biochemical basis for l-canavanine tolerance by the tobacco budworm Heliothis virescens (Noctuidae)
Coromoto Melangeli, Gerald A. Rosenthal, and Douglas L. Dalman
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2255–2260.
PMCID: PMC20074
Poly(ADP-ribose) polymerase enhances activator-dependent transcription in vitro
Michael Meisterernst, Gertraud Stelzer, and Robert G. Roeder
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2261–2265.
PMCID: PMC20075
UV-induced mutagenesis of human p53 in a vector replicated in Saccharomyces cerevisiae
Deborah J. Moshinsky and Gerald N. Wogan
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2266–2271.
PMCID: PMC20076
Enhancer blocking activity located near the 3′ end of the sea urchin early H2A histone gene
Franco Palla, Raffaella Melfi, Letizia Anello, Maria Di Bernardo, and Giovanni Spinelli
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2272–2277.
PMCID: PMC20077
Coexpression of nuclear receptor partners increases their solubility and biological activities
Chuan Li, John W. R. Schwabe, Ester Banayo, and Ronald M. Evans
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2278–2283.
PMCID: PMC20078
Establishment of methylation-sensitive–representational difference analysis and isolation of hypo- and hypermethylated genomic fragments in mouse liver tumors
Toshikazu Ushijima, Keiichirou Morimura, Yoko Hosoya, Hideo Okonogi, Masae Tatematsu, Takashi Sugimura, and Minako Nagao
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2284–2289.
PMCID: PMC20079
Observations on catalysis by hammerhead ribozymes are consistent with a two-divalent-metal-ion mechanism
Brian W. Pontius, William B. Lott, and Peter H. von Hippel
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2290–2294.
PMCID: PMC20080
Stat5 is a physiological substrate of the insulin receptor
Jing Chen, Henry B. Sadowski, Ronald A. Kohanski, and Lu-Hai Wang
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2295–2300.
PMCID: PMC20081
Biophysics
Feedback inhibition of Ca2+ channels by Ca2+ depends on a short sequence of the C terminus that does not include the Ca2+-binding function of a motif with similarity to Ca2+-binding domains
Jianming Zhou, Riccardo Olcese, Ning Qin, Francesca Noceti, Lutz Birnbaumer, and Enrico Stefani
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2301–2305.
PMCID: PMC20082
Structural basis for dual excitation and photoisomerization of the Aequorea victoria green fluorescent protein
Katjuša Brejc, Titia K. Sixma, Paul A. Kitts, Steven R. Kain, Roger Y. Tsien, Mats Ormö, and S. James Remington
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2306–2311.
PMCID: PMC20083
Stepped versus continuous rotatory motors at the molecular scale
Dirk Sabbert and Wolfgang Junge
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2312–2317.
PMCID: PMC20084
An elementary mode coupling theory of random heteropolymer dynamics
Shoji Takada, John J. Portman, and Peter G. Wolynes
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2318–2321.
PMCID: PMC20085
Single amino acid residue as a functional determinant of rod and cone visual pigments
Hiroo Imai, Daisuke Kojima, Tomonori Oura, Shuji Tachibanaki, Akihisa Terakita, and Yoshinori Shichida
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2322–2326.
PMCID: PMC20086
The structure of mitogen-activated protein kinase p38 at 2.1-Å resolution
Zhulun Wang, Paul C. Harkins, Richard J. Ulevitch, Jiahuai Han, Melanie H. Cobb, and Elizabeth J. Goldsmith
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2327–2332.
PMCID: PMC20087
Cell Biology
COOH-terminal sequence of the cellular prion protein directs subcellular trafficking and controls conversion into the scrapie isoform
Kiyotoshi Kaneko, Martin Vey, Michael Scott, Susanne Pilkuhn, Fred E. Cohen, and Stanley B. Prusiner
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2333–2338.
PMCID: PMC20088
Quantitative analysis of biological membrane lipids at the low picomole level by nano-electrospray ionization tandem mass spectrometry
B. Brügger, G. Erben, R. Sandhoff, F. T. Wieland, and W. D. Lehmann
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2339–2344.
PMCID: PMC20089
bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis
Mila E. McCurrach, Thomas M. F. Connor, C. Michael Knudson, Stanley J. Korsmeyer, and Scott W. Lowe
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2345–2349.
PMCID: PMC20090
Dissecting the thrombopoietin receptor: Functional elements of the Mpl cytoplasmic domain
Jonathan G. Drachman and Kenneth Kaushansky
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2350–2355.
PMCID: PMC20091
Downstream of Crk adaptor signaling pathway: Activation of Jun kinase by v-Crk through the guanine nucleotide exchange protein C3G
Shinya Tanaka, Toru Ouchi, and Hidesaburo Hanafusa
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2356–2361.
PMCID: PMC20092
Dominant-negative cyclin-selective ubiquitin carrier protein E2-C/UbcH10 blocks cells in metaphase
Fiona M. Townsley, Alexander Aristarkhov, Sharon Beck, Avram Hershko, and Joan V. Ruderman
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2362–2367.
PMCID: PMC20093
Identification of the second cluster of ligand-binding repeats in megalin as a site for receptor–ligand interactions
Robert A. Orlando, Markus Exner, Ralf-Peter Czekay, Hajime Yamazaki, Akihiko Saito, Robert Ullrich, Dontscho Kerjaschki, and Marilyn Gist Farquhar
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2368–2373.
PMCID: PMC20094
cDNA cloning and expression of bovine procollagen I N-proteinase: A new member of the superfamily of zinc-metalloproteinases with binding sites for cells and other matrix components
Alain Colige, Shi-Wu Li, Aleksander L. Sieron, Betty V. Nusgens, Darwin J. Prockop, and Charles M. Lapière
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2374–2379.
PMCID: PMC20095
Aberrant trafficking of hepatitis B virus glycoproteins in cells in which N-glycan processing is inhibited
Xuanyong Lu, Anand Mehta, Mitra Dadmarz, Raymond Dwek, Baruch S. Blumberg, and Timothy M. Block
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2380–2385.
PMCID: PMC20096
Developmental Biology
Expression of a dominant-negative type II transforming growth factor β (TGF-β) receptor in the epidermis of transgenic mice blocks TGF-β-mediated growth inhibition
Xiao-Jing Wang, David A. Greenhalgh, Jackie R. Bickenbach, Aibo Jiang, Donnie S. Bundman, Thomas Krieg, Rik Derynck, and Dennis R. Roop
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2386–2391.
PMCID: PMC20097
Function and regulation of heat shock factor 2 during mouse embryogenesis
M. Rallu, Mt. Loones, Y. Lallemand, R. Morimoto, M. Morange, and V. Mezger
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2392–2397.
PMCID: PMC20098
Molecular characterization of Br-cadherin, a developmentally regulated, brain-specific cadherin
Sara Selig, Hart G. W. Lidov, Sandra A. Bruno, Michael M. Segal, and Louis M. Kunkel
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2398–2403.
PMCID: PMC20099
Hedgehog signaling regulates transcription through cubitus interruptus, a sequence-specific DNA binding protein
Tonia Von Ohlen, Derek Lessing, Roel Nusse, and Joan E. Hooper
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2404–2409.
PMCID: PMC20100
Four highly stable eukaryotic mRNAs assemble 3′ untranslated region RNA–protein complexes sharing cis and trans components
Martin Holcik and Stephen A. Liebhaber
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2410–2414.
PMCID: PMC20101
Evolution
Floral homeotic genes were recruited from homologous MADS-box genes preexisting in the common ancestor of ferns and seed plants
Thomas Münster, Jens Pahnke, Alexandra Di Rosa, Jan T. Kim, William Martin, Heinz Saedler, and Günter Theissen
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2415–2420.
PMCID: PMC20102
Squid Pax-6 and eye development
Stanislav I. Tomarev, Patrick Callaerts, Lidia Kos, Rina Zinovieva, Georg Halder, Walter Gehring, and Joram Piatigorsky
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2421–2426.
PMCID: PMC20103
Genetics
Mutational studies of yeast transcription factor IIB in vivo reveal a functional surface important for gene activation
Shruti P. Shaw, Daniel J. Carson, Michael J. Dorsey, and Jun Ma
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2427–2432.
PMCID: PMC20104
egl-17 encodes an invertebrate fibroblast growth factor family member required specifically for sex myoblast migration in Caenorhabditis elegans
Rebecca D. Burdine, Estella B. Chen, Shing F. Kwok, and Michael J. Stern
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2433–2437.
PMCID: PMC20105
Nonsense mutation at Tyr-4046 in the DNA-dependent protein kinase catalytic subunit of severe combined immune deficiency mice
Ryoko Araki, Akira Fujimori, Kiyohiro Hamatani, Kazuei Mita, Toshiyuki Saito, Masahiko Mori, Ryutaro Fukumura, Mitsuoki Morimyo, Masahiro Muto, Masahiro Itoh, Kouichi Tatsumi, and Masumi Abe
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2438–2443.
PMCID: PMC20106
Binary transgenic mouse model for studying the trans control of globin gene switching: Evidence that GATA-1 is an in vivo repressor of human [var epsilon] gene expression
Qiliang Li, Christopher Clegg, Kenneth Peterson, Sara Shaw, Natacha Raich, and George Stamatoyannopoulos
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2444–2448.
PMCID: PMC20107
Detection of heterozygous truncating mutations in the BRCA1 and APC genes by using a rapid screening assay in yeast
Chikashi Ishioka, Takao Suzuki, Michael FitzGerald, Michael Krainer, Hideki Shimodaira, Akira Shimada, Tadashi Nomizu, Kurt J. Isselbacher, Daniel Haber, and Ryunosuke Kanamaru
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2449–2453.
PMCID: PMC20108
Immunology
Exploring the basis of peptide–carbohydrate crossreactivity: Evidence for discrimination by peptides between closely related anti-carbohydrate antibodies
Shannon L. Harris, Lisa Craig, Jarnail S. Mehroke, Michael Rashed, Michael B. Zwick, Kelly Kenar, Eric J. Toone, Neil Greenspan, France-Isabelle Auzanneau, José-R. Marino-Albernas, B. Mario Pinto, and Jamie K. Scott
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2454–2459.
PMCID: PMC20109
Lymphotoxin-β receptor signaling complex: Role of tumor necrosis factor receptor-associated factor 3 recruitment in cell death and activation of nuclear factor κB
Todd L. VanArsdale, Sammee L. VanArsdale, Walker R. Force, Barbara N. Walter, George Mosialos, Elliott Kieff, John C. Reed, and Carl F. Ware
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2460–2465.
PMCID: PMC20110
The pentamer channel stiffening model for drug action on human rhinovirus HRV-1A
Nagarajan Vaidehi and William A. Goddard, III
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2466–2471.
PMCID: PMC20111
Generation of NK1.1+ T cell antigen receptor α/β+ thymocytes associated with intact thymic structure
Ken-ichi Nakagawa, Kazuya Iwabuchi, Kazumasa Ogasawara, Manabu Ato, Masaharu Kajiwara, Hiroki Nishihori, Chikako Iwabuchi, Hiroshi Ishikura, Robert A. Good, and Kazunori Onoé
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2472–2477.
PMCID: PMC20112
Impairment of antigen-specific antibody production in transgenic mice expressing a dominant-negative form of gp130
Atsushi Kumanogoh, Satoko Marukawa, Takayuki Kumanogoh, Hisao Hirota, Kenji Yoshida, Ihn-Sook Lee, Teruhito Yasui, Kanji Yoshida, Tetsuya Taga, and Tadamitsu Kishimoto
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2478–2482.
PMCID: PMC20113
T cells cooperate with passive antibody to modify Cryptococcus neoformans infection in mice
RuiRong Yuan, Arturo Casadevall, Jin Oh, and Matthew D. Scharff
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2483–2488.
PMCID: PMC20114
Genetically engineered superantigens as tolerable antitumor agents
Johan Hansson, Lennart Ohlsson, Robert Persson, Gunnar Andersson, Nils-Gunnar Ilbäck, Mark J. Litton, Terje Kalland, and Mikael Dohlsten
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2489–2494.
PMCID: PMC20115
Stability of empty and peptide-loaded class II major histocompatibility complex molecules at neutral and endosomal pH: Comparison to class I proteins
Ziv Reich, John D. Altman, J. Jay Boniface, Daniel S. Lyons, Haruo Kozono, Graham Ogg, Chantal Morgan, and Mark M. Davis
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2495–2500.
PMCID: PMC20116
Importance of acidic, proline/serine/threonine-rich, and GTPbinding regions in the major histocompatibility complex class II transactivator: Generation of transdominant-negative mutants
Keh-Chuang Chin, George G.-X. Li, and Jenny P.-Y. Ting
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2501–2506.
PMCID: PMC20117
Fig1, an interleukin 4-induced mouse B cell gene isolated by cDNA representational difference analysis
Charles C. Chu and William E. Paul
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2507–2512.
PMCID: PMC20118
Pluripotent hemopoietic stem cells are c-kit<low
Hiroshi Doi, Muneo Inaba, Yoshihisa Yamamoto, Shigeru Taketani, Shin-Ichiro Mori, Akira Sugihara, Hajime Ogata, Junko Toki, Hiroko Hisha, Kayo Inaba, Shinji Sogo, Masakazu Adachi, Tadashi Matsuda, Robert A. Good, and Susumu Ikehara
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2513–2517.
PMCID: PMC20119
T cell receptor restriction of diabetogenic autoimmune NOD T cells
E. Simone, D. Daniel, N. Schloot, P. Gottlieb, S. Babu, E. Kawasaki, D. Wegmann, and G. S. Eisenbarth
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2518–2521.
PMCID: PMC20120
Medical Sciences
Point mutations at the purine nucleoside phosphorylase locus impair thymocyte differentiation in the mouse
Floyd F. Snyder, Jack P. Jenuth, Ellen R. Mably, and Rupinder K. Mangat
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2522–2527.
PMCID: PMC20121
Prevention of experimental allergic encephalomyelitis by targeting nitric oxide and peroxynitrite: Implications for the treatment of multiple sclerosis
D. Craig Hooper, Omar Bagasra, Joseph C. Marini, Anna Zborek, S. Tsuyoshi Ohnishi, Rhonda Kean, Jean M. Champion, Ashit B. Sarker, Lisa Bobroski, John L. Farber, Takaaki Akaike, Hiroshi Maeda, and Hilary Koprowski
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2528–2533.
PMCID: PMC20122
Immunohistochemistry of HLA-H, the protein defective in patients with hereditary hemochromatosis, reveals unique pattern of expression in gastrointestinal tract
Seppo Parkkila, Abdul Waheed, Robert S. Britton, John N. Feder, Zenta Tsuchihashi, Randall C. Schatzman, Bruce R. Bacon, and William S. Sly
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2534–2539.
PMCID: PMC20123
α-Galactosidase A deficient mice: A model of Fabry disease
Toshio Ohshima, Gary J. Murray, William D. Swaim, Glenn Longenecker, Jane M. Quirk, Carol O. Cardarelli, Yoshikazu Sugimoto, Ira Pastan, Michael M. Gottesman, Roscoe O. Brady, and Ashok B. Kulkarni
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2540–2544.
PMCID: PMC20124
DNA methylation and genetic instability in colorectal cancer cells
Christoph Lengauer, Kenneth W. Kinzler, and Bert Vogelstein
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2545–2550.
PMCID: PMC20125
A PMLRARα transgene initiates murine acute promyelocytic leukemia
Diane Brown, Scott Kogan, Eric Lagasse, Irving Weissman, Myriam Alcalay, Pier Giuseppe Pelicci, Susan Atwater, and J. Michael Bishop
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2551–2556.
PMCID: PMC20126
Obesity increases sensitivity to endotoxin liver injury: Implications for the pathogenesis of steatohepatitis
Shi Qi Yang, Hui Zhi Lin, M. Daniel Lane, Mark Clemens, and Anna Mae Diehl
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2557–2562.
PMCID: PMC20127
EEN encodes for a member of a new family of proteins containing an Src homology 3 domain and is the third gene located on chromosome 19p13 that fuses to MLL in human leukemia
Chi Wai So, Carlos Caldas, Meng-Min Liu, Sai-Juan Chen, Qiu-Hua Huang, Long-Jun Gu, Mai Har Sham, Leanne Marie Wiedemann, and Li Chong Chan
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2563–2568.
PMCID: PMC20128
Schizophrenia is associated with elevated amphetamine-induced synaptic dopamine concentrations: Evidence from a novel positron emission tomography method
A. Breier, T.-P. Su, R. Saunders, R. E. Carson, B. S. Kolachana, A. de Bartolomeis, D. R. Weinberger, N. Weisenfeld, A. K. Malhotra, W. C. Eckelman, and D. Pickar
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2569–2574.
PMCID: PMC20129
Transgenic mice expressing rabbit C-reactive protein are resistant to endotoxemia
Dongyuan Xia and David Samols
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2575–2580.
PMCID: PMC20130
The quinone reductase gene: A unique estrogen receptor-regulated gene that is activated by antiestrogens
Monica M. Montano and Benita S. Katzenellenbogen
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2581–2586.
PMCID: PMC20131
Insertion of the adenoviral E3 region into a recombinant viral vector prevents antiviral humoral and cellular immune responses and permits long-term gene expression
Yaron Ilan, Gustavo Droguett, Namita Roy Chowdhury, Yongan Li, Krishna Sengupta, Narsing R. Thummala, Anne Davidson, Jayanta Roy Chowdhury, and Marshall S. Horwitz
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2587–2592.
PMCID: PMC20132
UDP activates a mucosal-restricted receptor on human nasal epithelial cells that is distinct from the P2Y2 receptor
Eduardo R. Lazarowski, Anthony M. Paradiso, William C. Watt, T. Kendall Harden, and Richard C. Boucher
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2599–2603.
PMCID: PMC20134
In vivo activation of the cystic fibrosis transmembrane conductance regulator mutant ΔF508 in murine nasal epithelium
Thomas J. Kelley, Kirk Thomas, Laura J. H. Milgram, and Mitchell L. Drumm
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2604–2608.
PMCID: PMC20135
Pivotal role for the NFIL3/E4BP4 transcription factor in interleukin 3-mediated survival of pro-B lymphocytes
Satoshi Ikushima, Takeshi Inukai, Toshiya Inaba, Stephen D. Nimer, John L. Cleveland, and A. Thomas Look
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2609–2614.
PMCID: PMC20136
Calorie restriction reduces the incidence of myeloid leukemia induced by a single whole-body radiation in C3H/He mice
Kazuko Yoshida, Tohru Inoue, Kumie Nojima, Yoko Hirabayashi, and Toshihiko Sado
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2615–2619.
PMCID: PMC20137
Mixed-backbone oligonucleotides as second generation antisense oligonucleotides: In vitro and in vivo studies
Sudhir Agrawal, Zhiwei Jiang, Qiuyan Zhao, Denise Shaw, Qiuyin Cai, Allysen Roskey, Lakshmi Channavajjala, Carl Saxinger, and Ruiwen Zhang
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2620–2625.
PMCID: PMC20138
Microbiology
A genetic system for Archaea of the genus Methanosarcina: Liposome-mediated transformation and construction of shuttle vectors
William W. Metcalf, Jun Kai Zhang, Ethel Apolinario, Kevin R. Sowers, and Ralph S. Wolfe
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2626–2631.
PMCID: PMC20139
Neurobiology
Barx2, a new homeobox gene of the Bar class, is expressed in neural and craniofacial structures during development
Frederick S. Jones, Chrissa Kioussi, Donald W. Copertino, Pekka Kallunki, Brent D. Holst, and Gerald M. Edelman
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2632–2637.
PMCID: PMC20140
A novel seizure-induced synaptotagmin gene identified by differential display
Joseph M. Babity, John N. Armstrong, J.-Christophe L. Plumier, R. William Currie, and Harold A. Robertson
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2638–2641.
PMCID: PMC20141
Transcription factor NF-κB is activated in primary neurons by amyloid β peptides and in neurons surrounding early plaques from patients with Alzheimer disease
Barbara Kaltschmidt, Martin Uherek, Benedikt Volk, Patrick A. Baeuerle, and Christian Kaltschmidt
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2642–2647.
PMCID: PMC20142
Neuritin: A gene induced by neural activity and neurotrophins that promotes neuritogenesis
Gregory S. Naeve, Meena Ramakrishnan, Rainer Kramer, Dana Hevroni, Yoav Citri, and Lars E. Theill
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2648–2653.
PMCID: PMC20143
Induction by agrin of ectopic and functional postsynaptic-like membrane in innervated muscle
G. Jones, T. Meier, M. Lichtsteiner, V. Witzemann, B. Sakmann, and H. R. Brenner
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2654–2659.
PMCID: PMC20144
The location of the cochlear amplifier: Spatial representation of a single tone on the guinea pig basilar membrane
I. J. Russell and K. E. Nilsen
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2660–2664.
PMCID: PMC20145
Decreased probability of neurotransmitter release underlies striatal long-term depression and postnatal development of corticostriatal synapses
Sukwoo Choi and David M. Lovinger
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2665–2670.
PMCID: PMC20146
Dual activity maps in primate visual cortex produced by different temporal patterns of zif268 mRNA and protein expression
Avi Chaudhuri, Jonathan Nissanov, Sylvie Larocque, and Lise Rioux
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2671–2675.
PMCID: PMC20147
Neuronal (type I) nitric oxide synthase regulates nuclear factorκB activity and immunologic (type II) nitric oxide synthase expression
Hitoshi Togashi, Masayuki Sasaki, Elliot Frohman, Eichi Taira, Rajiv R. Ratan, Ted M. Dawson, and Valina L. Dawson
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2676–2680.
PMCID: PMC20148
Hyperresponsive febrile reactions to interleukin (IL) 1α and IL-1β, and altered brain cytokine mRNA and serum cytokine levels, in IL-1β-deficient mice
Katarina Alheim, Zhen Chai, Giamila Fantuzzi, Homa Hasanvan, David Malinowsky, Elena Di Santo, Pietro Ghezzi, Charles A. Dinarello, and Tamas Bartfai
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2681–2686.
PMCID: PMC20149
Glucocorticoid receptor pathways are involved in the inhibition of astrocyte proliferation
Kathryn L. Crossin, Ming-Hong Tai, Leslie A. Krushel, Vincent P. Mauro, and Gerald M. Edelman
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2687–2692.
PMCID: PMC20150
Antisense oligodeoxynucleotide-mediated disruption of hippocampal cAMP response element binding protein levels impairs consolidation of memory for water maze training
John F. Guzowski and James L. McGaugh
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2693–2698.
PMCID: PMC20151
In vivo 13C NMR measurements of cerebral glutamine synthesis as evidence for glutamate–glutamine cycling
N. R. Sibson, A. Dhankhar, G. F. Mason, K. L. Behar, D. L. Rothman, and R. G. Shulman
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2699–2704.
PMCID: PMC20152
Pharmacology
Regulation of intestinal uroguanylin/guanylin receptor-mediated responses by mucosal acidity
F. Kent Hamra, Sammy L. Eber, David T. Chin, Mark G. Currie, and Leonard R. Forte
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2705–2710.
PMCID: PMC20153
A surface on the G protein β-subunit involved in interactions with adenylyl cyclases
Yibang Chen, Gezhi Weng, Jinrong Li, Anya Harry, Joseph Pieroni, Jane Dingus, John D. Hildebrandt, Frank Guarnieri, Harel Weinstein, and Ravi Iyengar
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2711–2714.
PMCID: PMC20154
Irreversible antagonism of 5HT2c receptors by N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ)
Y. G. Ni, N. Camacho, and R. Miledi
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2715–2718.
PMCID: PMC20155
Alprazolam dependence prevented by substituting with the β-carboline abecarnil
Graziano Pinna, Ruggero Galici, Herbert H. Schneider, David N. Stephens, and Lechoslaw Turski
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2719–2723.
PMCID: PMC20156
Regulation of sodium channel gene expression by class I antiarrhythmic drugs and n − 3 polyunsaturated fatty acids in cultured neonatal rat cardiac myocytes
Jing X. Kang, Yunyuan Li, and Alexander Leaf
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2724–2728.
PMCID: PMC20157
Physiology
A mutation in autosomal dominant myotonia congenita affects pore properties of the muscle chloride channel
Christoph Fahlke, Carol L. Beck, and Alfred L. George, Jr.
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2729–2734.
PMCID: PMC20158
Targeting transforming growth factor α expression to discrete loci of the neuroendocrine brain induces female sexual precocity
Florence Rage, Diane F. Hill, Miguel Sena-Esteves, Xandra O. Breakefield, Robert J. Coffey, Maria E. Costa, Samuel M. McCann, and Sergio R. Ojeda
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2735–2740.
PMCID: PMC20159
Oxytocin stimulates the release of luteinizing hormone-releasing hormone from medial basal hypothalamic explants by releasing nitric oxide
V. Rettori, G. Canteros, R. Renoso, M. Gimeno, and S. M. McCann
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2741–2744.
PMCID: PMC20160
Plant Biology
Cell proliferation and hair tip growth in the Arabidopsis root are under mechanistically different forms of redox control
Rocío Sánchez-Fernández, Mark Fricker, Liz B. Corben, Nick S. White, Nicki Sheard, Christopher J. Leaver, Marc Van Montagu, Dirk Inzé, and Mike J. May
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2745–2750.
PMCID: PMC20161
Receptor-mediated activation of a plant Ca2+-permeable ion channel involved in pathogen defense
Sabine Zimmermann, Thorsten Nürnberger, Jean-Marie Frachisse, Wolfgang Wirtz, Jean Guern, Rainer Hedrich, and Dierk Scheel
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2751–2755.
PMCID: PMC20162
Ethylene can stimulate Arabidopsis hypocotyl elongation in the light
Jan Smalle, Mira Haegman, Jasmina Kurepa, Marc Van Montagu, and Dominique Van Der Straeten
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2756–2761.
PMCID: PMC20163
Population Biology
Early mortality surge in protein-deprived females causes reversal of sex differential of life expectancy in Mediterranean fruit flies
Hans-Georg Müller, Jane-Ling Wang, William B. Capra, Pablo Liedo, and James R. Carey
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2762–2765.
PMCID: PMC20164
Social Sciences
Psychology
Severe spatial navigation deficit in the Morris water maze after single high dose of neonatal x-ray irradiation in the rat
András Czurkó, Boldizsár Czéh, László Seress, Lynn Nadel, and Jan Bures
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2766–2771.
PMCID: PMC20165
Social Sciences
Chronic disability trends in elderly United States populations: 1982–1994
Kenneth G. Manton, Larry Corder, and Eric Stallard
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2593–2598.
PMCID: PMC20133
Correction
Proc Natl Acad Sci U S A. 1997 March 18; 94(6): 2772.
PMCID: PMC56216
Corrects: H Goldfine, et al. Membrane permeabilization by Listeria monocytogenes phosphatidylinositol-specific phospholipase C is independent of phospholipid hydrolysis and cooperative with listeriolysin O. Proc Natl Acad Sci U S A. 1995 March 28; 92(7): 2979–2983.
Other Issues:  previous | next | latest | archive