| | This journal provides immediate access to some articles. From the Academy Academy Honors 15 for Major Contributions to Science Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1349–1350. PMCID: PMC33821 Commentary Lightning strikes twice: Intron–intein coincidence Victoria Derbyshire and Marlene Belfort Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1356–1357. PMCID: PMC33822 Physical Sciences Chemistry Dynamical principles in biological processes E. W. Schlag, S. H. Lin, R. Weinkauf, and P. M. Rentzepis Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1358–1362. PMCID: PMC19004 A combinatorial approach to the discovery of efficient cationic peptoid reagents for gene delivery John E. Murphy, Tetsuo Uno, Janice D. Hamer, Fred E. Cohen, Varavani Dwarki, and Ronald N. Zuckermann Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1517–1522. PMCID: PMC19070 Mathematics Irregular arrays and randomization Burton H. Singer and Steve Pincus Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1363–1368. PMCID: PMC19005 Biological Sciences Applied Biological Sciences Farnesyl transferase inhibitors cause enhanced mitotic sensitivity to taxol and epothilones Mark M. Moasser, Laura Sepp-Lorenzino, Nancy E. Kohl, Allen Oliff, Aaron Balog, Dai-Shi Su, Samuel J. Danishefsky, and Neal Rosen Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1369–1374. PMCID: PMC19006 Biochemistry Amber suppression in Escherichia coli by unusual mitochondria-like transfer RNAs Véronique Bourdeau, Sergey V. Steinberg, Gerardo Ferbeyre, Rémi Emond, Nicolas Cermakian, and Robert Cedergren Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1375–1380. PMCID: PMC19007 Structural basis for methylesterase CheB regulation by a phosphorylation-activated domain Snezana Djordjevic, Paul N. Goudreau, Qingping Xu, Ann M. Stock, and Ann H. West Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1381–1386. PMCID: PMC19010 Parathyroid hormone activation of the 25-hydroxyvitamin D3-1α-hydroxylase gene promoter Holly L. Brenza, Christine Kimmel-Jehan, Frederic Jehan, Toshimasa Shinki, Shu Wakino, Hideharu Anazawa, Tatsuo Suda, and Hector F. DeLuca Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1387–1391. PMCID: PMC19012 Suppression of cell transformation by the cyclin-dependent kinase inhibitor p57KIP2 requires binding to proliferating cell nuclear antigen Hiroyuki Watanabe, Zhen-Qiang Pan, Nicole Schreiber-Agus, Ronald A. DePinho, Jerard Hurwitz, and Yue Xiong Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1392–1397. PMCID: PMC19016 Peptide nucleic acid-targeted mutagenesis of a chromosomal gene in mouse cells A. Fawad Faruqi, Michael Egholm, and Peter M. Glazer Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1398–1403. PMCID: PMC19018 DNA-binding domains of Fos and Jun do not induce DNA curvature: An investigation with solution and gel methods Ayesha Sitlani and Donald M. Crothers Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1404–1409. PMCID: PMC19021 Characterization of the ATF/CREB site and its complex with GCN4 Susan C. Hockings, Jason D. Kahn, and Donald M. Crothers Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1410–1415. PMCID: PMC19024 Real-time enzyme kinetics monitored by dual-color fluorescence
cross-correlation spectroscopy Ulrich Kettling, Andre Koltermann, Petra Schwille, and Manfred Eigen Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1416–1420. PMCID: PMC19026 Rapid assay processing by integration of dual-color fluorescence cross-correlation spectroscopy: High throughput screening for enzyme activity Andre Koltermann, Ulrich Kettling, Jan Bieschke, Thorsten Winkler, and Manfred Eigen Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1421–1426. PMCID: PMC19028 Monomolecular collapse of plasmid DNA into stable virus-like particles Thomas Blessing, Jean-Serge Remy, and Jean-Paul Behr Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1427–1431. PMCID: PMC19030 RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1 Patrick E. Burnett, Roxanne K. Barrow, Noam A. Cohen, Solomon H. Snyder, and David M. Sabatini Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1432–1437. PMCID: PMC19032 The complementary aggregation sites of fibrin investigated through examination of polymers of fibrinogen with fragment E Yuri Veklich, Esther K. Ang, Laszlo Lorand, and John W. Weisel Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1438–1442. PMCID: PMC19035 An essential, multicomponent signal transduction pathway required for cell cycle regulation in Caulobacter Jianguo Wu, Noriko Ohta, and Austin Newton Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1443–1448. PMCID: PMC19037 RNA polymerase of vesicular stomatitis virus specifically associates with translation elongation factor-1 αβγ for its activity Tapas Das, Manjula Mathur, Ashim K. Gupta, George M. C. Janssen, and Amiya K. Banerjee Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1449–1454. PMCID: PMC19039 Bcl-2 prevents apoptotic mitochondrial dysfunction by regulating proton flux Shigeomi Shimizu, Yutaka Eguchi, Wataru Kamiike, Yoshimitsu Funahashi, Alexandre Mignon, Virginia Lacronique, Hikaru Matsuda, and Yoshihide Tsujimoto Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1455–1459. PMCID: PMC19042 A unified view of polymer, dumbbell, and oligonucleotide DNA
nearest-neighbor thermodynamics John SantaLucia, Jr. Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1460–1465. PMCID: PMC19045 Membrane targeting of cGMP-dependent protein kinase is required for cystic fibrosis transmembrane conductance regulator Cl− channel activation Arie. B. Vaandrager, Albert Smolenski, Ben C. Tilly, Adriaan B. Houtsmuller, Ehrich M. E. Ehlert, Alice G. M. Bot, Marcel Edixhoven, Wendy E. M. Boomaars, Suzanne M. Lohmann, and Hugo R. de Jonge Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1466–1471. PMCID: PMC19047 The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding John N. Feder, David M. Penny, Alivelu Irrinki, Vince K. Lee, José A. Lebrón, Nicole Watson, Zenta Tsuchihashi, Elliott Sigal, Pamela J. Bjorkman, and Randall C. Schatzman Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1472–1477. PMCID: PMC19050 Intermolecular cleavage by UmuD-like mutagenesis proteins John P. McDonald, Ekaterina G. Frank, Arthur S. Levine, and Roger Woodgate Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1478–1483. PMCID: PMC19053 Depletion of Ca2+ from the sarcoplasmic reticulum of cardiac muscle prompts phosphorylation of phospholamban to stimulate store refilling Moninder Singh Bhogal and John Colyer Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1484–1489. PMCID: PMC19055 Is the molten globule a third phase of proteins? Vijay S. Pande and Daniel S. Rokhsar Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1490–1494. PMCID: PMC19058 Two chaperone sites in Hsp90 differing in substrate specificity and ATP dependence Thomas Scheibel, Tina Weikl, and Johannes Buchner Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1495–1499. PMCID: PMC19060 Identification of hepatic nuclear factor 1 binding sites in the 5′ flanking region of the human phenylalanine hydroxylase gene: Implication of a dual function of phenylalanine hydroxylase stimulator in the phenylalanine hydroxylation system Xiang-Dong Lei and Seymour Kaufman Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1500–1504. PMCID: PMC19063 Structure of a complex between a cap analogue and mRNA guanylyl transferase demonstrates the structural chemistry of RNA capping Kjell Håkansson and Dale B. Wigley Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1505–1510. PMCID: PMC19065 A unique glucose-dependent apoptotic pathway induced by c-Myc Hyunsuk Shim, Yoon S. Chun, Brian C. Lewis, and Chi V. Dang Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1511–1516. PMCID: PMC19067 A combinatorial approach to the discovery of efficient cationic peptoid reagents for gene delivery John E. Murphy, Tetsuo Uno, Janice D. Hamer, Fred E. Cohen, Varavani Dwarki, and Ronald N. Zuckermann Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1517–1522. PMCID: PMC19070 Localization of F plasmid SopB protein to positions near the poles of Escherichiacolicells Sook-Kyung Kim and James C. Wang Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1523–1527. PMCID: PMC19073 A previously unidentified host protein protects retroviral DNA from autointegration Myung Soo Lee and Robert Craigie Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1528–1533. PMCID: PMC19075 Electrophoresis in lyotropic polymer liquid crystals Randolph L. Rill, Bruce R. Locke, Yingjie Liu, and David H. Van Winkle Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1534–1539. PMCID: PMC19077 Reconstitution of hyperacetylated, DNase I-sensitive chromatin characterized by high conformational flexibility of nucleosomal DNA Wladyslaw A. Krajewski and Peter B. Becker Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1540–1545. PMCID: PMC19080 Escherichia coli NusA is required for efficient RNA binding by phage HK022 Nun protein Randolph S. Watnick and Max E. Gottesman Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1546–1551. PMCID: PMC19084 Biophysics The pressure dependence of hydrophobic interactions is consistent with the observed pressure denaturation of proteins Gerhard Hummer, Shekhar Garde, Angel E. García, Michael E. Paulaitis, and Lawrence R. Pratt Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1552–1555. PMCID: PMC19087 Monitoring conformational dynamics of a single molecule by selective fluorescence spectroscopy C. Eggeling, J. R. Fries, L. Brand, R. Günther, and C. A. M. Seidel Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1556–1561. PMCID: PMC19090 Molecular picture of folding of a small α/β protein Felix B. Sheinerman and Charles L. Brooks, III Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1562–1567. PMCID: PMC19093 Cell Biology Signaling pathways underlying eosinophil cell motility revealed by using caged peptides Jeffery W. Walker, Susan H. Gilbert, Robert M. Drummond, Misato Yamada, R. Sreekumar, Robert E. Carraway, Mitsuo Ikebe, and Fredric S. Fay Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1568–1573. PMCID: PMC19097 The variable domain of nonassembled Ig light chains determines both their half-life and binding to the chaperone BiP Markus H. Skowronek, Linda M. Hendershot, and Ingrid G. Haas Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1574–1578. PMCID: PMC19100 Dynamics of surfactant release in alveolar type II cells Thomas Haller, Jörg Ortmayr, Franz Friedrich, Harald Völkl, and Paul Dietl Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1579–1584. PMCID: PMC19102 Intranuclear targeting of AML/CBFα regulatory factors to nuclear matrix-associated transcriptional domains Congmei Zeng, Sandra McNeil, Shirwin Pockwinse, Jeffrey Nickerson, Lindsay Shopland, Jeanne B. Lawrence, Sheldon Penman, Scott Hiebert, Jane B. Lian, André J. van Wijnen, Janet L. Stein, and Gary S. Stein Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1585–1589. PMCID: PMC19104 Energy-transducing thylakoid membranes remain highly impermeable to ions during protein translocation Sarah A. Teter and Steven M. Theg Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1590–1594. PMCID: PMC19107 Cell cycle-dependent subcellular localization of the TSG101 protein and mitotic and nuclear abnormalities associated with TSG101 deficiency Weiqiao Xie, Limin Li, and Stanley N. Cohen Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1595–1600. PMCID: PMC19109 Opium alkaloid noscapine is an antitumor agent that arrests metaphase and induces apoptosis in dividing cells Keqiang Ye, Yong Ke, Nagalakshmi Keshava, John Shanks, Judith A. Kapp, Rajeshwar R. Tekmal, John Petros, and Harish C. Joshi Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1601–1606. PMCID: PMC19111 Interaction of the HIV-1 Rev cofactor eukaryotic initiation factor 5A with ribosomal protein L5 Octavian Schatz, Martin Oft, Christiane Dascher, Michael Schebesta, Olaf Rosorius, Herbert Jaksche, Marika Dobrovnik, Dorian Bevec, and Joachim Hauber Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1607–1612. PMCID: PMC19115 Inhibition of inositol 1,4,5-trisphosphate-induced Ca 2+ release by cAMP-dependent protein kinase in a living cell Svetlana Tertyshnikova and Alan Fein Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1613–1617. PMCID: PMC19117 Subcellular metabolic transients and mitochondrial redox waves in heart cells Dmitry N. Romashko, Eduardo Marban, and Brian O’Rourke Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1618–1623. PMCID: PMC19119 Modulation of intracellular transport by transported proteins: Insight from regulation of COPI-mediated transport Tomohiko Aoe, Agnes J. Lee, Elly van Donselaar, Peter J. Peters, and Victor W. Hsu Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1624–1629. PMCID: PMC19122 Menin, the product of the MEN1 gene, is a nuclear protein Siradanahalli C. Guru, Paul K. Goldsmith, A. Lee Burns, Stephen J. Marx, Allen M. Spiegel, Francis S. Collins, and Settara C. Chandrasekharappa Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1630–1634. PMCID: PMC19125 Fast repair of O6-ethylguanine, but not O6-methylguanine, in transcribed genes prevents mutation of H-ras in rat mammary tumorigenesis induced by ethylnitrosourea in place of methylnitrosourea Jörg Engelbergs, Jürgen Thomale, Anke Galhoff, and Manfred F. Rajewsky Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1635–1640. PMCID: PMC19127 Developmental Biology Blood-borne seeding by hematopoietic and endothelial precursors from the allantois Arianna Caprioli, Thierry Jaffredo, Rodolphe Gautier, Cécile Dubourg, and Françoise Dieterlen-Lièvre Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1641–1646. PMCID: PMC19130 Evolution Abundant microsatellite polymorphism in Saccharomyces cerevisiae, and the different distributions of microsatellites in eight prokaryotes and S. cerevisiae, result from strong mutation pressures and a variety of selective forces Dawn Field and Christopher Wills Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1647–1652. PMCID: PMC19132 De novo insertion of an intron into the mammalian sex determining gene, SRY Rachel J. Waugh O’Neill, Francine E. Brennan, Margaret L. Delbridge, Ross H. Crozier, and Jennifer A. Marshall Graves Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1653–1657. PMCID: PMC19134 New Drosophila introns originate by duplication Rosa Tarrío, Francisco Rodríguez-Trelles, and Francisco J. Ayala Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1658–1662. PMCID: PMC19138 INAUGURAL ARTICLE by a Recently Elected Academy Member: Genetic traces of ancient demography Henry C. Harpending, Mark A. Batzer, Michael Gurven, Lynn B. Jorde, Alan R. Rogers, and Stephen T. Sherry Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1961–1967. PMCID: PMC19224 Genetics Expression of Xa1, a bacterial blight-resistance gene in rice, is induced by bacterial inoculation Satomi Yoshimura, Utako Yamanouchi, Yuichi Katayose, Seiichi Toki, Zi-Xuan Wang, Izumi Kono, Nori Kurata, Masahiro Yano, Nobuo Iwata, and Takuji Sasaki Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1663–1668. PMCID: PMC19140 Host cell killing and bacterial conjugation require overlapping sets of genes within a 22-kb region of the Legionella pneumophila genome Gil Segal, Mary Purcell, and Howard A. Shuman Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1669–1674. PMCID: PMC19142 Clonal heterogeneity at allelic methylation sites diagnostic for Prader–Willi and Angelman syndromes Janine M. LaSalle, Rachael J. Ritchie, Heather Glatt, and Marc Lalande Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1675–1680. PMCID: PMC19144 Conformation sensitive gel electrophoresis for simple and accurate detection of mutations: Comparison with denaturing gradient gel electrophoresis and nucleotide sequencing Jarmo Körkkö, Susanna Annunen, Tero Pihlajamaa, Darwin J. Prockop, and Leena Ala-Kokko Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1681–1685. PMCID: PMC19147 Plant–pathogen microevolution: Molecular basis for the origin of a fungal disease in maize D. S. Multani, R. B. Meeley, A. H. Paterson, J. Gray, S. P. Briggs, and G. S. Johal Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1686–1691. PMCID: PMC19149 Introns and intein coding sequence in the ribonucleotide reductase genes of Bacillus subtilis temperate bacteriophage SPβ Vladimir Lazarevic, Blazenka Soldo, Andreas Düsterhöft, Helmut Hilbert, Catherine Mauël, and Dimitri Karamata Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1692–1697. PMCID: PMC19153 Identification of a silencing element in the human 15q11-q13 imprinting center by using transgenic Drosophila Frank Lyko, Karin Buiting, Bernhard Horsthemke, and Renato Paro Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1698–1702. PMCID: PMC19156 Immunology Use of D gene segments with irregular spacers in terminal deoxynucleotidyltransferase (TdT) +/+ and TdT −/− mice carrying a human Ig heavy chain transgenic minilocus Nadine Tuaillon and J. Donald Capra Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1703–1708. PMCID: PMC19158 Mucosal immunization with HIV-1 peptide vaccine induces mucosal and systemic cytotoxic T lymphocytes and protective immunity in mice against intrarectal recombinant HIV-vaccinia challenge Igor M. Belyakov, Michael A. Derby, Jeffrey D. Ahlers, Brian L. Kelsall, Patricia Earl, Bernard Moss, Warren Strober, and Jay A. Berzofsky Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1709–1714. PMCID: PMC19159 Deletion of Plasmodium berghei-specific CD4 + T cells adoptively transferred into recipient mice after challenge with homologous parasite Chakrit Hirunpetcharat and Michael F. Good Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1715–1720. PMCID: PMC19161 Autoreactivity of T cells from nonobese diabetic mice: An I-A g7-dependent reaction Osami Kanagawa, Steven M. Martin, Barbara A. Vaupel, Eugenio Carrasco-Marin, and Emil R. Unanue Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1721–1724. PMCID: PMC19165 Primary CD8 + cells from HIV-infected individuals can suppress productive infection of macrophages independent of β-chemokines Edward Barker, Katharine N. Bossart, and Jay A. Levy Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1725–1729. PMCID: PMC19166 A role for B cells in the development of T cell helper function in a malaria infection in mice Jean Langhorne, Caroline Cross, Elsa Seixas, Ching Li, and Thierry von der Weid Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1730–1734. PMCID: PMC19169 Medical Sciences Prostate stem cell antigen: A cell surface marker overexpressed in prostate cancer Robert E. Reiter, Zhennen Gu, Tetsuro Watabe, George Thomas, Kinga Szigeti, Elizabeth Davis, Matthew Wahl, Sazuku Nisitani, Joyce Yamashiro, Michelle M. Le Beau, Massimo Loda, and Owen N. Witte Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1735–1740. PMCID: PMC19171 Mapping a disease locus by allelic association A. Collins and N. E. Morton Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1741–1745. PMCID: PMC19174 Attenuation of the Langat tick-borne flavivirus by chimerization with mosquito-borne flavivirus dengue type 4 Alexander G. Pletnev and Ruhe Men Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1746–1751. PMCID: PMC19176 Impact of antigenemia on the bioactivity of infused anti-Tac antibody: Implications for dose selection in antibody immunotherapies R. P. Junghans, J. A. Carrasquillo, and T. A. Waldmann Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1752–1757. PMCID: PMC19178 Role of cyclophilin A in the uptake of HIV-1 by macrophages and T lymphocytes Barbara Sherry, Gabriele Zybarth, Massimo Alfano, Larisa Dubrovsky, Robert Mitchell, Daniel Rich, Peter Ulrich, Richard Bucala, Anthony Cerami, and Michael Bukrinsky Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1758–1763. PMCID: PMC19180 Antisense inhibition of the PTI-1 oncogene reverses cancer phenotypes Zao-zhong Su, Neil I. Goldstein, and Paul B. Fisher Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1764–1769. PMCID: PMC19182 From differentiation to proliferation: The secretory amyloid precursor protein as a local mediator of growth in thyroid epithelial cells Claus Ulrich Pietrzik, Jens Hoffmann, Kai Stöber, Chun-Yan Chen, Christoph Bauer, Deborah A. C. Otero, Jean-Marc Roch, and Volker Herzog Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1770–1775. PMCID: PMC19185 Discovery of a human liver glycogen phosphorylase inhibitor that lowers blood glucose invivoWilliam H. Martin, Dennis J. Hoover, Sandra J. Armento, Ingrid A. Stock, R. Kirk McPherson, Dennis E. Danley, Ralph W. Stevenson, Eugene J. Barrett, and Judith L. Treadway Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1776–1781. PMCID: PMC19188 Genes in the pX region of human T cell leukemia virus I influence Vav phosphorylation in T cells W. Mahana, T. M. Zhao, R. Teller, M. A. Robinson, and T. J. Kindt Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1782–1787. PMCID: PMC19190 Basal expression of cyclooxygenase-2 and nuclear factor–interleukin 6 are dominant and coordinately regulated by interleukin 1 in the pancreatic islet Christopher H. Sorli, Hui-Jian Zhang, Michael B. Armstrong, Ray V. Rajotte, Jacques Maclouf, and R. Paul Robertson Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1788–1793. PMCID: PMC19191 Synthesis and biological evaluation of cytotoxic analogs of somatostatin containing doxorubicin or its intensely potent derivative, 2-pyrrolinodoxorubicin Attila Nagy, Andrew V. Schally, Gábor Halmos, Patricia Armatis, Ren-Zhi Cai, Valér Csernus, Magdolna Kovács, Miklós Koppán, Károly Szepesházi, and Zsuzsanna Kahán Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1794–1799. PMCID: PMC19192 Chimeric papillomavirus virus-like particles elicit antitumor immunity against the E7 oncoprotein in an HPV16 tumor model Heather L. Greenstone, John D. Nieland, Karin E. de Visser, Marloes L. H. De Bruijn, Reinhard Kirnbauer, Richard B. S. Roden, Douglas R. Lowy, W. Martin Kast, and John T. Schiller Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1800–1805. PMCID: PMC19193 Evidence that the lipid moiety of oxidized low density lipoprotein plays a role in its interaction with macrophage receptors Valeska Terpstra, David A. Bird, and Daniel Steinberg Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1806–1811. PMCID: PMC19194 Negative regulation of granulocytic differentiation in the myeloid precursor cell line 32Dcl3 by ear-2, a mammalian homolog of Drosophila seven-up, and a chimeric leukemogenic gene, AML1/ETO( MTG8) Mee-Young Ahn, Gang Huang, Suk-Chul Bae, Hee-Jun Wee, Woo-Young Kim, and Yoshiaki Ito Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1812–1817. PMCID: PMC19195 Microbiology Host-derived amino acids support the proliferation of symbiotic bacteria Joerg Graf and Edward G. Ruby Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1818–1822. PMCID: PMC19196 New protein kinase and protein phosphatase families mediate signal transduction in bacterial catabolite repression Anne Galinier, Melanie Kravanja, Roswitha Engelmann, Wolfgang Hengstenberg, Marie-Claude Kilhoffer, Josef Deutscher, and Jacques Haiech Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1823–1828. PMCID: PMC19197 Modulation of Neisseria gonorrhoeae susceptibility to vertebrate antibacterial peptides due to a member of the resistance/nodulation/division efflux pump family W. M. Shafer, X.-D. Qu, A. J. Waring, and R. I. Lehrer Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1829–1833. PMCID: PMC19198 Neurobiology Calibrated functional MRI: Mapping the dynamics of oxidative metabolism Timothy L. Davis, Kenneth K. Kwong, Robert M. Weisskoff, and Bruce R. Rosen Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1834–1839. PMCID: PMC19199 An in vitro blood–brain barrier model: Cocultures between endothelial cells and organotypic brain slice cultures S. Duport, F. Robert, D. Muller, G. Grau, L. Parisi, and L. Stoppini Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1840–1845. PMCID: PMC19200 Distinct functional stoichiometry of potassium channel β subunits Jia Xu, Weifeng Yu, Jerry M. Wright, Ronald W. Raab, and Min Li Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1846–1851. PMCID: PMC19201 Dehydroepiandrosterone (DHEA) and DHEA-sulfate (DHEAS) protect hippocampal neurons against excitatory amino acid-induced neurotoxicity V. G. Kimonides, N. H. Khatibi, C. N. Svendsen, M. V. Sofroniew, and J. Herbert Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1852–1857. PMCID: PMC19202 Ex vivo nerve growth factor gene transfer to the basal forebrain in presymptomatic middle-aged rats prevents the development of cholinergic neuron atrophy and cognitive impairment during aging Alberto Martínez-Serrano and Anders Björklund Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1858–1863. PMCID: PMC19203 Repeated pulses of serotonin required for long-term facilitation activate mitogen-activated protein kinase in sensory neurons of AplysiaDan Michael, Kelsey C. Martin, Rony Seger, Ming-Ming Ning, Rene Baston, and Eric R. Kandel Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1864–1869. PMCID: PMC19204 Rapping, a female receptive call, initiates male–female duets in the South African clawed frog Martha L. Tobias, Sandya S. Viswanathan, and Darcy B. Kelley Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1870–1875. PMCID: PMC19205 A pineal regulatory element (PIRE) mediates transactivation by the pineal/retina-specific transcription factor CRX Xiaodong Li, Shiming Chen, Qingliang Wang, Donald J. Zack, Solomon H. Snyder, and Jimo Borjigin Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1876–1881. PMCID: PMC19206 Activation of Kv3.1 channels in neuronal spine-like structures may induce local potassium ion depletion Lu-Yang Wang, Li Gan, Teresa M. Perney, Ilsa Schwartz, and Leonard K. Kaczmarek Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1882–1887. PMCID: PMC19207 Activity-dependent regulation of Neu differentiation factor/neuregulin expression in rat brain Raya Eilam, Ronit Pinkas-Kramarski, Barry J. Ratzkin, Menahem Segal, and Yosef Yarden Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1888–1893. PMCID: PMC19208 Pharmacology Displacement of insulin-like growth factors from their binding proteins as a potential treatment for stroke Sarah A. Loddick, Xin-Jun Liu, Zi-Xian Lu, Changlu Liu, Dominic P. Behan, Derek C. Chalmers, Alan C. Foster, Wylie W. Vale, Nicholas Ling, and Errol B. De Souza Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1894–1898. PMCID: PMC19209 Molecular cloning and expression of the human Δ7-sterol reductase Fabian F. Moebius, Barbara U. Fitzky, Joon No Lee, Young-Ki Paik, and Hartmut Glossmann Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1899–1902. PMCID: PMC19210 Physiology Tagging with green fluorescent protein reveals a distinct subcellular distribution of L-type and non-L-type Ca 2+ channels expressed in dysgenic myotubes Manfred Grabner, Robert T. Dirksen, and Kurt G. Beam Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1903–1908. PMCID: PMC19211 Parathyroid hormone leads to the lysosomal degradation of the renal type II Na/Pi cotransporter Markus F. Pfister, Isabelle Ruf, Gerti Stange, Urs Ziegler, Eleanor Lederer, Jürg Biber, and Heini Murer Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1909–1914. PMCID: PMC19212 Our ancestral physiological phenotype: An adaptation for hypoxia tolerance and for endurance performance? Peter W. Hochachka, Hanns Christian Gunga, and Karl Kirsch Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1915–1920. PMCID: PMC19213 Identification and characterization of a cell membrane nucleic acid channel Basil Hanss, Edgar Leal-Pinto, Leslie A. Bruggeman, Terry D. Copeland, and Paul E. Klotman Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1921–1926. PMCID: PMC19214 HIV gp120 inhibits the somatotropic axis: A possible GH-releasing hormone receptor mechanism for the pathogenesis of AIDS wasting Susan E. Mulroney, Kevin J. McDonnell, Candace B. Pert, Michael R. Ruff, Zachary Resch, Willis K. Samson, and Michael D. Lumpkin Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1927–1932. PMCID: PMC19215 Plant Biology Ethylene-insensitive tobacco lacks nonhost resistance against soil-borne fungi Marga Knoester, Leendert C. van Loon, Joop van den Heuvel, Jacek Hennig, John F. Bol, and Huub J. M. Linthorst Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1933–1937. PMCID: PMC19216 MP2C, a plant protein phosphatase 2C, functions as a negative regulator of mitogen-activated protein kinase pathways in yeast and plants Irute Meskiene, Laszlo Bögre, Walter Glaser, Judit Balog, Markus Brandstötter, Karin Zwerger, Gustav Ammerer, and Heribert Hirt Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1938–1943. PMCID: PMC19217 Characterization of a calmodulin-binding transporter from the plasma membrane of barley aleurone Robert C. Schuurink, Stacey F. Shartzer, Angelika Fath, and Russell L. Jones Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1944–1949. PMCID: PMC19218 Phosphate availability affects the thylakoid lipid composition and the expression of SQD1, a gene required for sulfolipid biosynthesis in Arabidopsis thaliana Bernd Essigmann, Sinan Güler, Ram Avtar Narang, Dirk Linke, and Christoph Benning Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1950–1955. PMCID: PMC19220 Psychology Where the imaginal appears real: A positron emission tomography study of auditory hallucinations Henry Szechtman, Erik Woody, Kenneth S. Bowers, and Claude Nahmias Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1956–1960. PMCID: PMC19222 Social Sciences Anthropology INAUGURAL ARTICLE by a Recently Elected Academy Member: Genetic traces of ancient demography Henry C. Harpending, Mark A. Batzer, Michael Gurven, Lynn B. Jorde, Alan R. Rogers, and Stephen T. Sherry Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1961–1967. PMCID: PMC19224 Corrections Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1968. PMCID: PMC56006 Corrects: Liang-Jun Yan, et al. Oxidative damage during aging targets mitochondrialaconitase. Proc Natl Acad Sci U S A. 1997 October 14; 94(21): 11168–11172. Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1968. PMCID: PMC56007 Corrects: Peter D. Yurchenco, et al. The α chain of laminin-1 is independently secreted and drives secretion of its β- and γ-chainpartners. Proc Natl Acad Sci U S A. 1997 September 16; 94(19): 10189–10194. Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1968. PMCID: PMC56008 Corrects: Yan Chen, et al. Smad8 mediates the signaling of the receptor serinekinase. Proc Natl Acad Sci U S A. 1997 November 25; 94(24): 12938–12943. Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1968. PMCID: PMC56009 Corrects: Francisco J. Cifuentes, et al. Proximo–distal specification in the wing disc of Drosophila by thenubbingene. Proc Natl Acad Sci U S A. 1997 October 14; 94(21): 11405–11410. Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1968. PMCID: PMC56010 Corrects: T Leitner, et al. Accurate reconstruction of a known HIV-1 transmission history by phylogenetic tree analysis. Proc Natl Acad Sci U S A. 1996 October 1; 93(20): 10864–10869. |