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Volume 95(4);  February 17, 1998
From the Academy
Academy Honors 15 for Major Contributions to Science
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1349–1350.
PMCID: PMC33821
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Commentary
Lightning strikes twice: Intron–intein coincidence
Victoria Derbyshire and Marlene Belfort
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1356–1357.
PMCID: PMC33822
Physical Sciences
Chemistry
Dynamical principles in biological processes
E. W. Schlag, S. H. Lin, R. Weinkauf, and P. M. Rentzepis
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1358–1362.
PMCID: PMC19004
A combinatorial approach to the discovery of efficient cationic peptoid reagents for gene delivery
John E. Murphy, Tetsuo Uno, Janice D. Hamer, Fred E. Cohen, Varavani Dwarki, and Ronald N. Zuckermann
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1517–1522.
PMCID: PMC19070
Mathematics
Irregular arrays and randomization
Burton H. Singer and Steve Pincus
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1363–1368.
PMCID: PMC19005
Biological Sciences
Applied Biological Sciences
Farnesyl transferase inhibitors cause enhanced mitotic sensitivity to taxol and epothilones
Mark M. Moasser, Laura Sepp-Lorenzino, Nancy E. Kohl, Allen Oliff, Aaron Balog, Dai-Shi Su, Samuel J. Danishefsky, and Neal Rosen
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1369–1374.
PMCID: PMC19006
Biochemistry
Amber suppression in Escherichia coli by unusual mitochondria-like transfer RNAs
Véronique Bourdeau, Sergey V. Steinberg, Gerardo Ferbeyre, Rémi Emond, Nicolas Cermakian, and Robert Cedergren
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1375–1380.
PMCID: PMC19007
Structural basis for methylesterase CheB regulation by a phosphorylation-activated domain
Snezana Djordjevic, Paul N. Goudreau, Qingping Xu, Ann M. Stock, and Ann H. West
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1381–1386.
PMCID: PMC19010
Parathyroid hormone activation of the 25-hydroxyvitamin D3-1α-hydroxylase gene promoter
Holly L. Brenza, Christine Kimmel-Jehan, Frederic Jehan, Toshimasa Shinki, Shu Wakino, Hideharu Anazawa, Tatsuo Suda, and Hector F. DeLuca
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1387–1391.
PMCID: PMC19012
Suppression of cell transformation by the cyclin-dependent kinase inhibitor p57KIP2 requires binding to proliferating cell nuclear antigen
Hiroyuki Watanabe, Zhen-Qiang Pan, Nicole Schreiber-Agus, Ronald A. DePinho, Jerard Hurwitz, and Yue Xiong
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1392–1397.
PMCID: PMC19016
Peptide nucleic acid-targeted mutagenesis of a chromosomal gene in mouse cells
A. Fawad Faruqi, Michael Egholm, and Peter M. Glazer
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1398–1403.
PMCID: PMC19018
DNA-binding domains of Fos and Jun do not induce DNA curvature: An investigation with solution and gel methods
Ayesha Sitlani and Donald M. Crothers
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1404–1409.
PMCID: PMC19021
Characterization of the ATF/CREB site and its complex with GCN4
Susan C. Hockings, Jason D. Kahn, and Donald M. Crothers
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1410–1415.
PMCID: PMC19024
Real-time enzyme kinetics monitored by dual-color fluorescence cross-correlation spectroscopy
Ulrich Kettling, Andre Koltermann, Petra Schwille, and Manfred Eigen
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1416–1420.
PMCID: PMC19026
Rapid assay processing by integration of dual-color fluorescence cross-correlation spectroscopy: High throughput screening for enzyme activity
Andre Koltermann, Ulrich Kettling, Jan Bieschke, Thorsten Winkler, and Manfred Eigen
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1421–1426.
PMCID: PMC19028
Monomolecular collapse of plasmid DNA into stable virus-like particles
Thomas Blessing, Jean-Serge Remy, and Jean-Paul Behr
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1427–1431.
PMCID: PMC19030
RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1
Patrick E. Burnett, Roxanne K. Barrow, Noam A. Cohen, Solomon H. Snyder, and David M. Sabatini
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1432–1437.
PMCID: PMC19032
The complementary aggregation sites of fibrin investigated through examination of polymers of fibrinogen with fragment E
Yuri Veklich, Esther K. Ang, Laszlo Lorand, and John W. Weisel
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1438–1442.
PMCID: PMC19035
An essential, multicomponent signal transduction pathway required for cell cycle regulation in Caulobacter
Jianguo Wu, Noriko Ohta, and Austin Newton
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1443–1448.
PMCID: PMC19037
RNA polymerase of vesicular stomatitis virus specifically associates with translation elongation factor-1 αβγ for its activity
Tapas Das, Manjula Mathur, Ashim K. Gupta, George M. C. Janssen, and Amiya K. Banerjee
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1449–1454.
PMCID: PMC19039
Bcl-2 prevents apoptotic mitochondrial dysfunction by regulating proton flux
Shigeomi Shimizu, Yutaka Eguchi, Wataru Kamiike, Yoshimitsu Funahashi, Alexandre Mignon, Virginia Lacronique, Hikaru Matsuda, and Yoshihide Tsujimoto
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1455–1459.
PMCID: PMC19042
A unified view of polymer, dumbbell, and oligonucleotide DNA nearest-neighbor thermodynamics
John SantaLucia, Jr.
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1460–1465.
PMCID: PMC19045
Membrane targeting of cGMP-dependent protein kinase is required for cystic fibrosis transmembrane conductance regulator Cl channel activation
Arie. B. Vaandrager, Albert Smolenski, Ben C. Tilly, Adriaan B. Houtsmuller, Ehrich M. E. Ehlert, Alice G. M. Bot, Marcel Edixhoven, Wendy E. M. Boomaars, Suzanne M. Lohmann, and Hugo R. de Jonge
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1466–1471.
PMCID: PMC19047
The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding
John N. Feder, David M. Penny, Alivelu Irrinki, Vince K. Lee, José A. Lebrón, Nicole Watson, Zenta Tsuchihashi, Elliott Sigal, Pamela J. Bjorkman, and Randall C. Schatzman
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1472–1477.
PMCID: PMC19050
Intermolecular cleavage by UmuD-like mutagenesis proteins
John P. McDonald, Ekaterina G. Frank, Arthur S. Levine, and Roger Woodgate
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1478–1483.
PMCID: PMC19053
Depletion of Ca2+ from the sarcoplasmic reticulum of cardiac muscle prompts phosphorylation of phospholamban to stimulate store refilling
Moninder Singh Bhogal and John Colyer
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1484–1489.
PMCID: PMC19055
Is the molten globule a third phase of proteins?
Vijay S. Pande and Daniel S. Rokhsar
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1490–1494.
PMCID: PMC19058
Two chaperone sites in Hsp90 differing in substrate specificity and ATP dependence
Thomas Scheibel, Tina Weikl, and Johannes Buchner
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1495–1499.
PMCID: PMC19060
Identification of hepatic nuclear factor 1 binding sites in the 5′ flanking region of the human phenylalanine hydroxylase gene: Implication of a dual function of phenylalanine hydroxylase stimulator in the phenylalanine hydroxylation system
Xiang-Dong Lei and Seymour Kaufman
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1500–1504.
PMCID: PMC19063
Structure of a complex between a cap analogue and mRNA guanylyl transferase demonstrates the structural chemistry of RNA capping
Kjell Håkansson and Dale B. Wigley
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1505–1510.
PMCID: PMC19065
A unique glucose-dependent apoptotic pathway induced by c-Myc
Hyunsuk Shim, Yoon S. Chun, Brian C. Lewis, and Chi V. Dang
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1511–1516.
PMCID: PMC19067
A combinatorial approach to the discovery of efficient cationic peptoid reagents for gene delivery
John E. Murphy, Tetsuo Uno, Janice D. Hamer, Fred E. Cohen, Varavani Dwarki, and Ronald N. Zuckermann
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1517–1522.
PMCID: PMC19070
Localization of F plasmid SopB protein to positions near the poles of Escherichia coli cells
Sook-Kyung Kim and James C. Wang
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1523–1527.
PMCID: PMC19073
A previously unidentified host protein protects retroviral DNA from autointegration
Myung Soo Lee and Robert Craigie
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1528–1533.
PMCID: PMC19075
Electrophoresis in lyotropic polymer liquid crystals
Randolph L. Rill, Bruce R. Locke, Yingjie Liu, and David H. Van Winkle
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1534–1539.
PMCID: PMC19077
Reconstitution of hyperacetylated, DNase I-sensitive chromatin characterized by high conformational flexibility of nucleosomal DNA
Wladyslaw A. Krajewski and Peter B. Becker
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1540–1545.
PMCID: PMC19080
Escherichia coli NusA is required for efficient RNA binding by phage HK022 Nun protein
Randolph S. Watnick and Max E. Gottesman
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1546–1551.
PMCID: PMC19084
Biophysics
The pressure dependence of hydrophobic interactions is consistent with the observed pressure denaturation of proteins
Gerhard Hummer, Shekhar Garde, Angel E. García, Michael E. Paulaitis, and Lawrence R. Pratt
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1552–1555.
PMCID: PMC19087
Monitoring conformational dynamics of a single molecule by selective fluorescence spectroscopy
C. Eggeling, J. R. Fries, L. Brand, R. Günther, and C. A. M. Seidel
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1556–1561.
PMCID: PMC19090
Molecular picture of folding of a small α/β protein
Felix B. Sheinerman and Charles L. Brooks, III
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1562–1567.
PMCID: PMC19093
Cell Biology
Signaling pathways underlying eosinophil cell motility revealed by using caged peptides
Jeffery W. Walker, Susan H. Gilbert, Robert M. Drummond, Misato Yamada, R. Sreekumar, Robert E. Carraway, Mitsuo Ikebe, and Fredric S. Fay
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1568–1573.
PMCID: PMC19097
The variable domain of nonassembled Ig light chains determines both their half-life and binding to the chaperone BiP
Markus H. Skowronek, Linda M. Hendershot, and Ingrid G. Haas
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1574–1578.
PMCID: PMC19100
Dynamics of surfactant release in alveolar type II cells
Thomas Haller, Jörg Ortmayr, Franz Friedrich, Harald Völkl, and Paul Dietl
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1579–1584.
PMCID: PMC19102
Intranuclear targeting of AML/CBFα regulatory factors to nuclear matrix-associated transcriptional domains
Congmei Zeng, Sandra McNeil, Shirwin Pockwinse, Jeffrey Nickerson, Lindsay Shopland, Jeanne B. Lawrence, Sheldon Penman, Scott Hiebert, Jane B. Lian, André J. van Wijnen, Janet L. Stein, and Gary S. Stein
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1585–1589.
PMCID: PMC19104
Energy-transducing thylakoid membranes remain highly impermeable to ions during protein translocation
Sarah A. Teter and Steven M. Theg
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1590–1594.
PMCID: PMC19107
Cell cycle-dependent subcellular localization of the TSG101 protein and mitotic and nuclear abnormalities associated with TSG101 deficiency
Weiqiao Xie, Limin Li, and Stanley N. Cohen
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1595–1600.
PMCID: PMC19109
Opium alkaloid noscapine is an antitumor agent that arrests metaphase and induces apoptosis in dividing cells
Keqiang Ye, Yong Ke, Nagalakshmi Keshava, John Shanks, Judith A. Kapp, Rajeshwar R. Tekmal, John Petros, and Harish C. Joshi
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1601–1606.
PMCID: PMC19111
Interaction of the HIV-1 Rev cofactor eukaryotic initiation factor 5A with ribosomal protein L5
Octavian Schatz, Martin Oft, Christiane Dascher, Michael Schebesta, Olaf Rosorius, Herbert Jaksche, Marika Dobrovnik, Dorian Bevec, and Joachim Hauber
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1607–1612.
PMCID: PMC19115
Inhibition of inositol 1,4,5-trisphosphate-induced Ca2+ release by cAMP-dependent protein kinase in a living cell
Svetlana Tertyshnikova and Alan Fein
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1613–1617.
PMCID: PMC19117
Subcellular metabolic transients and mitochondrial redox waves in heart cells
Dmitry N. Romashko, Eduardo Marban, and Brian O’Rourke
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1618–1623.
PMCID: PMC19119
Modulation of intracellular transport by transported proteins: Insight from regulation of COPI-mediated transport
Tomohiko Aoe, Agnes J. Lee, Elly van Donselaar, Peter J. Peters, and Victor W. Hsu
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1624–1629.
PMCID: PMC19122
Menin, the product of the MEN1 gene, is a nuclear protein
Siradanahalli C. Guru, Paul K. Goldsmith, A. Lee Burns, Stephen J. Marx, Allen M. Spiegel, Francis S. Collins, and Settara C. Chandrasekharappa
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1630–1634.
PMCID: PMC19125
Fast repair of O6-ethylguanine, but not O6-methylguanine, in transcribed genes prevents mutation of H-ras in rat mammary tumorigenesis induced by ethylnitrosourea in place of methylnitrosourea
Jörg Engelbergs, Jürgen Thomale, Anke Galhoff, and Manfred F. Rajewsky
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1635–1640.
PMCID: PMC19127
Developmental Biology
Blood-borne seeding by hematopoietic and endothelial precursors from the allantois
Arianna Caprioli, Thierry Jaffredo, Rodolphe Gautier, Cécile Dubourg, and Françoise Dieterlen-Lièvre
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1641–1646.
PMCID: PMC19130
Evolution
Abundant microsatellite polymorphism in Saccharomyces cerevisiae, and the different distributions of microsatellites in eight prokaryotes and S. cerevisiae, result from strong mutation pressures and a variety of selective forces
Dawn Field and Christopher Wills
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1647–1652.
PMCID: PMC19132
De novo insertion of an intron into the mammalian sex determining gene, SRY
Rachel J. Waugh O’Neill, Francine E. Brennan, Margaret L. Delbridge, Ross H. Crozier, and Jennifer A. Marshall Graves
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1653–1657.
PMCID: PMC19134
New Drosophila introns originate by duplication
Rosa Tarrío, Francisco Rodríguez-Trelles, and Francisco J. Ayala
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1658–1662.
PMCID: PMC19138
Genetic traces of ancient demography
Henry C. Harpending, Mark A. Batzer, Michael Gurven, Lynn B. Jorde, Alan R. Rogers, and Stephen T. Sherry
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1961–1967.
PMCID: PMC19224
Genetics
Expression of Xa1, a bacterial blight-resistance gene in rice, is induced by bacterial inoculation
Satomi Yoshimura, Utako Yamanouchi, Yuichi Katayose, Seiichi Toki, Zi-Xuan Wang, Izumi Kono, Nori Kurata, Masahiro Yano, Nobuo Iwata, and Takuji Sasaki
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1663–1668.
PMCID: PMC19140
Host cell killing and bacterial conjugation require overlapping sets of genes within a 22-kb region of the Legionella pneumophila genome
Gil Segal, Mary Purcell, and Howard A. Shuman
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1669–1674.
PMCID: PMC19142
Clonal heterogeneity at allelic methylation sites diagnostic for Prader–Willi and Angelman syndromes
Janine M. LaSalle, Rachael J. Ritchie, Heather Glatt, and Marc Lalande
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1675–1680.
PMCID: PMC19144
Conformation sensitive gel electrophoresis for simple and accurate detection of mutations: Comparison with denaturing gradient gel electrophoresis and nucleotide sequencing
Jarmo Körkkö, Susanna Annunen, Tero Pihlajamaa, Darwin J. Prockop, and Leena Ala-Kokko
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1681–1685.
PMCID: PMC19147
Plant–pathogen microevolution: Molecular basis for the origin of a fungal disease in maize
D. S. Multani, R. B. Meeley, A. H. Paterson, J. Gray, S. P. Briggs, and G. S. Johal
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1686–1691.
PMCID: PMC19149
Introns and intein coding sequence in the ribonucleotide reductase genes of Bacillus subtilis temperate bacteriophage SPβ
Vladimir Lazarevic, Blazenka Soldo, Andreas Düsterhöft, Helmut Hilbert, Catherine Mauël, and Dimitri Karamata
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1692–1697.
PMCID: PMC19153
Identification of a silencing element in the human 15q11-q13 imprinting center by using transgenic Drosophila
Frank Lyko, Karin Buiting, Bernhard Horsthemke, and Renato Paro
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1698–1702.
PMCID: PMC19156
Immunology
Use of D gene segments with irregular spacers in terminal deoxynucleotidyltransferase (TdT)+/+ and TdT−/− mice carrying a human Ig heavy chain transgenic minilocus
Nadine Tuaillon and J. Donald Capra
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1703–1708.
PMCID: PMC19158
Mucosal immunization with HIV-1 peptide vaccine induces mucosal and systemic cytotoxic T lymphocytes and protective immunity in mice against intrarectal recombinant HIV-vaccinia challenge
Igor M. Belyakov, Michael A. Derby, Jeffrey D. Ahlers, Brian L. Kelsall, Patricia Earl, Bernard Moss, Warren Strober, and Jay A. Berzofsky
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1709–1714.
PMCID: PMC19159
Deletion of Plasmodium berghei-specific CD4+ T cells adoptively transferred into recipient mice after challenge with homologous parasite
Chakrit Hirunpetcharat and Michael F. Good
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1715–1720.
PMCID: PMC19161
Autoreactivity of T cells from nonobese diabetic mice: An I-Ag7-dependent reaction
Osami Kanagawa, Steven M. Martin, Barbara A. Vaupel, Eugenio Carrasco-Marin, and Emil R. Unanue
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1721–1724.
PMCID: PMC19165
Primary CD8+ cells from HIV-infected individuals can suppress productive infection of macrophages independent of β-chemokines
Edward Barker, Katharine N. Bossart, and Jay A. Levy
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1725–1729.
PMCID: PMC19166
A role for B cells in the development of T cell helper function in a malaria infection in mice
Jean Langhorne, Caroline Cross, Elsa Seixas, Ching Li, and Thierry von der Weid
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1730–1734.
PMCID: PMC19169
Medical Sciences
Prostate stem cell antigen: A cell surface marker overexpressed in prostate cancer
Robert E. Reiter, Zhennen Gu, Tetsuro Watabe, George Thomas, Kinga Szigeti, Elizabeth Davis, Matthew Wahl, Sazuku Nisitani, Joyce Yamashiro, Michelle M. Le Beau, Massimo Loda, and Owen N. Witte
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1735–1740.
PMCID: PMC19171
Mapping a disease locus by allelic association
A. Collins and N. E. Morton
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1741–1745.
PMCID: PMC19174
Attenuation of the Langat tick-borne flavivirus by chimerization with mosquito-borne flavivirus dengue type 4
Alexander G. Pletnev and Ruhe Men
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1746–1751.
PMCID: PMC19176
Impact of antigenemia on the bioactivity of infused anti-Tac antibody: Implications for dose selection in antibody immunotherapies
R. P. Junghans, J. A. Carrasquillo, and T. A. Waldmann
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1752–1757.
PMCID: PMC19178
Role of cyclophilin A in the uptake of HIV-1 by macrophages and T lymphocytes
Barbara Sherry, Gabriele Zybarth, Massimo Alfano, Larisa Dubrovsky, Robert Mitchell, Daniel Rich, Peter Ulrich, Richard Bucala, Anthony Cerami, and Michael Bukrinsky
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1758–1763.
PMCID: PMC19180
Antisense inhibition of the PTI-1 oncogene reverses cancer phenotypes
Zao-zhong Su, Neil I. Goldstein, and Paul B. Fisher
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1764–1769.
PMCID: PMC19182
From differentiation to proliferation: The secretory amyloid precursor protein as a local mediator of growth in thyroid epithelial cells
Claus Ulrich Pietrzik, Jens Hoffmann, Kai Stöber, Chun-Yan Chen, Christoph Bauer, Deborah A. C. Otero, Jean-Marc Roch, and Volker Herzog
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1770–1775.
PMCID: PMC19185
Discovery of a human liver glycogen phosphorylase inhibitor that lowers blood glucose in vivo
William H. Martin, Dennis J. Hoover, Sandra J. Armento, Ingrid A. Stock, R. Kirk McPherson, Dennis E. Danley, Ralph W. Stevenson, Eugene J. Barrett, and Judith L. Treadway
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1776–1781.
PMCID: PMC19188
Genes in the pX region of human T cell leukemia virus I influence Vav phosphorylation in T cells
W. Mahana, T. M. Zhao, R. Teller, M. A. Robinson, and T. J. Kindt
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1782–1787.
PMCID: PMC19190
Basal expression of cyclooxygenase-2 and nuclear factor–interleukin 6 are dominant and coordinately regulated by interleukin 1 in the pancreatic islet
Christopher H. Sorli, Hui-Jian Zhang, Michael B. Armstrong, Ray V. Rajotte, Jacques Maclouf, and R. Paul Robertson
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1788–1793.
PMCID: PMC19191
Synthesis and biological evaluation of cytotoxic analogs of somatostatin containing doxorubicin or its intensely potent derivative, 2-pyrrolinodoxorubicin
Attila Nagy, Andrew V. Schally, Gábor Halmos, Patricia Armatis, Ren-Zhi Cai, Valér Csernus, Magdolna Kovács, Miklós Koppán, Károly Szepesházi, and Zsuzsanna Kahán
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1794–1799.
PMCID: PMC19192
Chimeric papillomavirus virus-like particles elicit antitumor immunity against the E7 oncoprotein in an HPV16 tumor model
Heather L. Greenstone, John D. Nieland, Karin E. de Visser, Marloes L. H. De Bruijn, Reinhard Kirnbauer, Richard B. S. Roden, Douglas R. Lowy, W. Martin Kast, and John T. Schiller
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1800–1805.
PMCID: PMC19193
Evidence that the lipid moiety of oxidized low density lipoprotein plays a role in its interaction with macrophage receptors
Valeska Terpstra, David A. Bird, and Daniel Steinberg
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1806–1811.
PMCID: PMC19194
Negative regulation of granulocytic differentiation in the myeloid precursor cell line 32Dcl3 by ear-2, a mammalian homolog of Drosophila seven-up, and a chimeric leukemogenic gene, AML1/ETO(MTG8)
Mee-Young Ahn, Gang Huang, Suk-Chul Bae, Hee-Jun Wee, Woo-Young Kim, and Yoshiaki Ito
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1812–1817.
PMCID: PMC19195
Microbiology
Host-derived amino acids support the proliferation of symbiotic bacteria
Joerg Graf and Edward G. Ruby
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1818–1822.
PMCID: PMC19196
New protein kinase and protein phosphatase families mediate signal transduction in bacterial catabolite repression
Anne Galinier, Melanie Kravanja, Roswitha Engelmann, Wolfgang Hengstenberg, Marie-Claude Kilhoffer, Josef Deutscher, and Jacques Haiech
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1823–1828.
PMCID: PMC19197
Modulation of Neisseria gonorrhoeae susceptibility to vertebrate antibacterial peptides due to a member of the resistance/nodulation/division efflux pump family
W. M. Shafer, X.-D. Qu, A. J. Waring, and R. I. Lehrer
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1829–1833.
PMCID: PMC19198
Neurobiology
Calibrated functional MRI: Mapping the dynamics of oxidative metabolism
Timothy L. Davis, Kenneth K. Kwong, Robert M. Weisskoff, and Bruce R. Rosen
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1834–1839.
PMCID: PMC19199
An in vitro blood–brain barrier model: Cocultures between endothelial cells and organotypic brain slice cultures
S. Duport, F. Robert, D. Muller, G. Grau, L. Parisi, and L. Stoppini
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1840–1845.
PMCID: PMC19200
Distinct functional stoichiometry of potassium channel β subunits
Jia Xu, Weifeng Yu, Jerry M. Wright, Ronald W. Raab, and Min Li
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1846–1851.
PMCID: PMC19201
Dehydroepiandrosterone (DHEA) and DHEA-sulfate (DHEAS) protect hippocampal neurons against excitatory amino acid-induced neurotoxicity
V. G. Kimonides, N. H. Khatibi, C. N. Svendsen, M. V. Sofroniew, and J. Herbert
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1852–1857.
PMCID: PMC19202
Ex vivo nerve growth factor gene transfer to the basal forebrain in presymptomatic middle-aged rats prevents the development of cholinergic neuron atrophy and cognitive impairment during aging
Alberto Martínez-Serrano and Anders Björklund
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1858–1863.
PMCID: PMC19203
Repeated pulses of serotonin required for long-term facilitation activate mitogen-activated protein kinase in sensory neurons of Aplysia
Dan Michael, Kelsey C. Martin, Rony Seger, Ming-Ming Ning, Rene Baston, and Eric R. Kandel
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1864–1869.
PMCID: PMC19204
Rapping, a female receptive call, initiates male–female duets in the South African clawed frog
Martha L. Tobias, Sandya S. Viswanathan, and Darcy B. Kelley
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1870–1875.
PMCID: PMC19205
A pineal regulatory element (PIRE) mediates transactivation by the pineal/retina-specific transcription factor CRX
Xiaodong Li, Shiming Chen, Qingliang Wang, Donald J. Zack, Solomon H. Snyder, and Jimo Borjigin
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1876–1881.
PMCID: PMC19206
Activation of Kv3.1 channels in neuronal spine-like structures may induce local potassium ion depletion
Lu-Yang Wang, Li Gan, Teresa M. Perney, Ilsa Schwartz, and Leonard K. Kaczmarek
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1882–1887.
PMCID: PMC19207
Activity-dependent regulation of Neu differentiation factor/neuregulin expression in rat brain
Raya Eilam, Ronit Pinkas-Kramarski, Barry J. Ratzkin, Menahem Segal, and Yosef Yarden
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1888–1893.
PMCID: PMC19208
Pharmacology
Displacement of insulin-like growth factors from their binding proteins as a potential treatment for stroke
Sarah A. Loddick, Xin-Jun Liu, Zi-Xian Lu, Changlu Liu, Dominic P. Behan, Derek C. Chalmers, Alan C. Foster, Wylie W. Vale, Nicholas Ling, and Errol B. De Souza
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1894–1898.
PMCID: PMC19209
Molecular cloning and expression of the human Δ7-sterol reductase
Fabian F. Moebius, Barbara U. Fitzky, Joon No Lee, Young-Ki Paik, and Hartmut Glossmann
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1899–1902.
PMCID: PMC19210
Physiology
Tagging with green fluorescent protein reveals a distinct subcellular distribution of L-type and non-L-type Ca2+ channels expressed in dysgenic myotubes
Manfred Grabner, Robert T. Dirksen, and Kurt G. Beam
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1903–1908.
PMCID: PMC19211
Parathyroid hormone leads to the lysosomal degradation of the renal type II Na/Pi cotransporter
Markus F. Pfister, Isabelle Ruf, Gerti Stange, Urs Ziegler, Eleanor Lederer, Jürg Biber, and Heini Murer
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1909–1914.
PMCID: PMC19212
Our ancestral physiological phenotype: An adaptation for hypoxia tolerance and for endurance performance?
Peter W. Hochachka, Hanns Christian Gunga, and Karl Kirsch
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1915–1920.
PMCID: PMC19213
Identification and characterization of a cell membrane nucleic acid channel
Basil Hanss, Edgar Leal-Pinto, Leslie A. Bruggeman, Terry D. Copeland, and Paul E. Klotman
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1921–1926.
PMCID: PMC19214
HIV gp120 inhibits the somatotropic axis: A possible GH-releasing hormone receptor mechanism for the pathogenesis of AIDS wasting
Susan E. Mulroney, Kevin J. McDonnell, Candace B. Pert, Michael R. Ruff, Zachary Resch, Willis K. Samson, and Michael D. Lumpkin
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1927–1932.
PMCID: PMC19215
Plant Biology
Ethylene-insensitive tobacco lacks nonhost resistance against soil-borne fungi
Marga Knoester, Leendert C. van Loon, Joop van den Heuvel, Jacek Hennig, John F. Bol, and Huub J. M. Linthorst
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1933–1937.
PMCID: PMC19216
MP2C, a plant protein phosphatase 2C, functions as a negative regulator of mitogen-activated protein kinase pathways in yeast and plants
Irute Meskiene, Laszlo Bögre, Walter Glaser, Judit Balog, Markus Brandstötter, Karin Zwerger, Gustav Ammerer, and Heribert Hirt
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1938–1943.
PMCID: PMC19217
Characterization of a calmodulin-binding transporter from the plasma membrane of barley aleurone
Robert C. Schuurink, Stacey F. Shartzer, Angelika Fath, and Russell L. Jones
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1944–1949.
PMCID: PMC19218
Phosphate availability affects the thylakoid lipid composition and the expression of SQD1, a gene required for sulfolipid biosynthesis in Arabidopsis thaliana
Bernd Essigmann, Sinan Güler, Ram Avtar Narang, Dirk Linke, and Christoph Benning
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1950–1955.
PMCID: PMC19220
Psychology
Where the imaginal appears real: A positron emission tomography study of auditory hallucinations
Henry Szechtman, Erik Woody, Kenneth S. Bowers, and Claude Nahmias
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1956–1960.
PMCID: PMC19222
Social Sciences
Anthropology
Genetic traces of ancient demography
Henry C. Harpending, Mark A. Batzer, Michael Gurven, Lynn B. Jorde, Alan R. Rogers, and Stephen T. Sherry
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1961–1967.
PMCID: PMC19224
Corrections
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1968.
PMCID: PMC56006
Corrects: Liang-Jun Yan, et al. Oxidative damage during aging targets mitochondrial aconitase. Proc Natl Acad Sci U S A. 1997 October 14; 94(21): 11168–11172.
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1968.
PMCID: PMC56007
Corrects: Peter D. Yurchenco, et al. The α chain of laminin-1 is independently secreted and drives secretion of its β- and γ-chain partners. Proc Natl Acad Sci U S A. 1997 September 16; 94(19): 10189–10194.
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1968.
PMCID: PMC56008
Corrects: Yan Chen, et al. Smad8 mediates the signaling of the receptor serine kinase. Proc Natl Acad Sci U S A. 1997 November 25; 94(24): 12938–12943.
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1968.
PMCID: PMC56009
Corrects: Francisco J. Cifuentes, et al. Proximo–distal specification in the wing disc of Drosophila by the nubbin gene. Proc Natl Acad Sci U S A. 1997 October 14; 94(21): 11405–11410.
Proc Natl Acad Sci U S A. 1998 February 17; 95(4): 1968.
PMCID: PMC56010
Corrects: T Leitner, et al. Accurate reconstruction of a known HIV-1 transmission history by phylogenetic tree analysis. Proc Natl Acad Sci U S A. 1996 October 1; 93(20): 10864–10869.
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