pmc logo imageJournal ListSearchpmc logo image
Logo of pnasPNAS Home page.PNAS Editorial BoardPNAS AboutPNAS SubscriptionsPNAS Info for Authors
This journal provides immediate access to some articles.
Other Issues:  previous | next | latest | archive
Volume 97(9);  April 25, 2000
Commentaries
Dietary flavonoids and the MLL gene: A pathway to infant leukemia?
Julie A. Ross
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4411–4413.
PMCID: PMC34309
Brain growth and the cognitive map
Alejandro Terrazas and Bruce L. McNaughton
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4414–4416.
PMCID: PMC34310
Absinthe and γ-aminobutyric acid receptors
Richard W. Olsen
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4417–4418.
PMCID: PMC34311
Allosteric activation of the CaR by l-amino acids
Brian Kobilka
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4419–4420.
PMCID: PMC34312
Polyamines in spermiogenesis: Not now, darling
Philip Coffino
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4421–4423.
PMCID: PMC34313
Perspective
Special Feature: The Cambrian “explosion”: Slow-fuse or megatonnage?
Simon Conway Morris
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4426–4429.
PMCID: PMC34314
Special Feature: Regulatory evolution and the origin of the bilaterians
Kevin J. Peterson and Eric H. Davidson
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4430–4433.
PMCID: PMC34315
Special Feature: Evolution of the bilaterian body plan: What have we learned from annelids?
Marty Shankland and Elaine C. Seaver
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4434–4437.
PMCID: PMC34316
Special Feature: Arthropods: Developmental diversity within a (super) phylum
Michael Akam
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4438–4441.
PMCID: PMC34317
Special Feature: It's a bug's life
Nipam H. Patel
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4442–4444.
PMCID: PMC34318
Special Feature: Inversion of the chordate body axis: Are there alternatives?
J. Gerhart
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4445–4448.
PMCID: PMC34319
Special Feature: Vertebrate innovations
Sebastian M. Shimeld and Peter W. H. Holland
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4449–4452.
PMCID: PMC34320
Special Feature: The new animal phylogeny: Reliability and implications
André Adoutte, Guillaume Balavoine, Nicolas Lartillot, Olivier Lespinet, Benjamin Prud'homme, and Renaud de Rosa
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4453–4456.
PMCID: PMC34321
Reviews
Special Feature: The origin of plants: Body plan changes contributing to a major evolutionary radiation
Linda E. Graham, Martha E. Cook, and James S. Busse
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4535–4540.
PMCID: PMC34322
PMD fundamentals: Polarization mode dispersion in optical fibers
J. P. Gordon and H. Kogelnik
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4541–4550.
PMCID: PMC34323
Special Features
The evolution of evo-devo biology
Corey S. Goodman and Bridget C. Coughlin
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4424–4425.
PMCID: PMC18255
Special Feature: The Cambrian “explosion”: Slow-fuse or megatonnage?
Simon Conway Morris
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4426–4429.
PMCID: PMC34314
Special Feature: Regulatory evolution and the origin of the bilaterians
Kevin J. Peterson and Eric H. Davidson
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4430–4433.
PMCID: PMC34315
Special Feature: Evolution of the bilaterian body plan: What have we learned from annelids?
Marty Shankland and Elaine C. Seaver
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4434–4437.
PMCID: PMC34316
Special Feature: Arthropods: Developmental diversity within a (super) phylum
Michael Akam
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4438–4441.
PMCID: PMC34317
Special Feature: It's a bug's life
Nipam H. Patel
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4442–4444.
PMCID: PMC34318
Special Feature: Inversion of the chordate body axis: Are there alternatives?
J. Gerhart
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4445–4448.
PMCID: PMC34319
Special Feature: Vertebrate innovations
Sebastian M. Shimeld and Peter W. H. Holland
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4449–4452.
PMCID: PMC34320
Special Feature: The new animal phylogeny: Reliability and implications
André Adoutte, Guillaume Balavoine, Nicolas Lartillot, Olivier Lespinet, Benjamin Prud'homme, and Renaud de Rosa
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4453–4456.
PMCID: PMC34321
Special Feature: Precambrian animal diversity: Putative phosphatized embryos from the Doushantuo Formation of China
Jun-Yuan Chen, Paola Oliveri, Chia-Wei Li, Gui-Qing Zhou, Feng Gao, James W. Hagadorn, Kevin J. Peterson, and Eric H. Davidson
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4457–4462.
PMCID: PMC18256
Special Feature: Evolution of biological complexity
Christoph Adami, Charles Ofria, and Travis C. Collier
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4463–4468.
PMCID: PMC18257
Special Feature: Evolution of the chordate body plan: New insights from phylogenetic analyses of deuterostome phyla
Chris B. Cameron, James R. Garey, and Billie J. Swalla
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4469–4474.
PMCID: PMC18258
Special Feature: Pax gene diversity in the basal cnidarian Acropora millepora (Cnidaria, Anthozoa): Implications for the evolution of the Pax gene family
David J. Miller, David C. Hayward, John S. Reece-Hoyes, Ingo Scholten, Julian Catmull, Walter J. Gehring, Patrick Callaerts, Jill E. Larsen, and Eldon E. Ball
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4475–4480.
PMCID: PMC18259
Special Feature: Analysis of a complete homeobox gene repertoire: Implications for the evolution of diversity
Claudia Kappen
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4481–4486.
PMCID: PMC18260
Special Feature: Quantitative assessment of Hox complex expression in the indirect development of the polychaete annelid Chaetopterus sp.
Kevin J. Peterson, Steven Q. Irvine, R. Andrew Cameron, and Eric H. Davidson
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4487–4492.
PMCID: PMC18261
Special Feature: Evolution of Antp-class genes and differential expression of Hydra Hox/paraHox genes in anterior patterning
Dominique Gauchat, Françoise Mazet, Cédric Berney, Michèl Schummer, Sylvia Kreger, Jan Pawlowski, and Brigitte Galliot
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4493–4498.
PMCID: PMC18262
Special Feature: Caenorhabditis elegans embryonic axial patterning requires two recently discovered posterior-group Hox genes
Kimberly Van Auken, Daniel C. Weaver, Lois G. Edgar, and William B. Wood
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4499–4503.
PMCID: PMC18263
Special Feature: Distinct roles of the homeotic genes Ubx and abd-A in beetle embryonic abdominal appendage development
David L. Lewis, Mark DeCamillis, and Randy L. Bennett
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4504–4509.
PMCID: PMC18264
Special Feature: Implications of the Tribolium Deformed mutant phenotype for the evolution of Hox gene function
Susan Brown, Mark DeCamillis, Karen Gonzalez-Charneco, Margaret Denell, Richard Beeman, Wensheng Nie, and Robin Denell
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4510–4514.
PMCID: PMC18265
Special Feature: Expression patterns of hairy, even-skipped, and runt in the spider Cupiennius salei imply that these genes were segmentation genes in a basal arthropod
Wim G. M. Damen, Mathias Weller, and Diethard Tautz
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4515–4519.
PMCID: PMC18266
Special Feature: Wnt/Shh interactions regulate ectodermal boundary formation during mammalian tooth development
Lena Sarkar, Martyn Cobourne, Stuart Naylor, Matthew Smalley, Trevor Dale, and Paul T. Sharpe
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4520–4524.
PMCID: PMC18267
Special Feature: Searching for the prototypic eye genetic network: Sine oculis is essential for eye regeneration in planarians
D. Pineda, J. Gonzalez, P. Callaerts, K. Ikeo, W. J. Gehring, and E. Salo
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4525–4529.
PMCID: PMC18268
Special Feature: Divergence of larval morphology between Drosophila sechellia and its sibling species caused by cis-regulatory evolution of ovo/shaven-baby
Élio Sucena and David L. Stern
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4530–4534.
PMCID: PMC18269
Special Feature: The origin of plants: Body plan changes contributing to a major evolutionary radiation
Linda E. Graham, Martha E. Cook, and James S. Busse
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4535–4540.
PMCID: PMC34322
Physical Sciences
Astronomy
Nebular and auroral emission lines of [Cl iii] in the optical spectra of planetary nebulae
Francis P. Keenan, Lawrence H. Aller, Catherine A. Ramsbottom, Kenneth L. Bell, Fergal L. Crawford, and Siek Hyung
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4551–4555. Published online 2000 April 4.
PMCID: PMC18270
Chemistry
Polarons in DNA
Esther M. Conwell and Svetlana V. Rakhmanova
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4556–4560. Published online 2000 April 11.
PMCID: PMC18271
Computer Sciences
Special Feature: Evolution of biological complexity
Christoph Adami, Charles Ofria, and Travis C. Collier
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4463–4468.
PMCID: PMC18257
Geophysics
Geoelectric potential changes: Possible precursors to earthquakes in Japan
S. Uyeda, T. Nagao, Y. Orihara, T. Yamaguchi, and I. Takahashi
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4561–4566.
PMCID: PMC18272
Biological Sciences
Biochemistry
Uncovering the [2Fe2S] domain movement in cytochrome bc1 and its implications for energy conversion
Elisabeth Darrouzet, Maria Valkova-Valchanova, Christopher C. Moser, P. Leslie Dutton, and Fevzi Daldal
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4567–4572.
PMCID: PMC18273
The crystal structure of palmitoyl protein thioesterase 1 and the molecular basis of infantile neuronal ceroid lipofuscinosis
John J. Bellizzi, III, Joanne Widom, Christopher Kemp, Jui-Yun Lu, Amit K. Das, Sandra L. Hofmann, and Jon Clardy
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4573–4578. Published online 2000 April 18.
PMCID: PMC18274
A Nedd8 conjugation pathway is essential for proteolytic targeting of p27Kip1 by ubiquitination
Vladimir N. Podust, James E. Brownell, Tatiana B. Gladysheva, Rong-Shu Luo, Chunhua Wang, Michael B. Coggins, Jacqueline W. Pierce, Eric S. Lightcap, and Vincent Chau
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4579–4584. Published online 2000 April 18.
PMCID: PMC18275
The in vitro and in vivo phosphotyrosine map of activated MuSK
Anke Watty, Gitte Neubauer, Mathias Dreger, Manuel Zimmer, Matthias Wilm, and Steven J. Burden
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4585–4590. Published online 2000 April 18.
PMCID: PMC18276
The Dewar photoproduct of thymidylyl(3′→5′)- thymidine (Dewar product) exhibits mutagenic behavior in accordance with the “A rule”
Joon-Hwa Lee, Sung-Hun Bae, and Byong-Seok Choi
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4591–4596. Published online 2000 April 11.
PMCID: PMC18277
Selecting rRNA binding sites for the ribosomal proteins L4 and L6 from randomly fragmented rRNA: Application of a method called SERF
Ulrich Stelzl, Christian M. T. Spahn, and Knud H. Nierhaus
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4597–4602. Published online 2000 April 18.
PMCID: PMC18278
Functional interaction between the Werner Syndrome protein and DNA polymerase δ
A. S. Kamath-Loeb, E. Johansson, P. M. J. Burgers, and L. A. Loeb
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4603–4608.
PMCID: PMC18279
The protein translocation channel mediates glycopeptide export across the endoplasmic reticulum membrane
Pauline Gillece, Marinus Pilon, and Karin Römisch
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4609–4614. Published online 2000 April 11.
PMCID: PMC18280
Raf induces NF-κB by membrane shuttle kinase MEKK1, a signaling pathway critical for transformation
Bernd Baumann, Christoph K. Weber, Jakob Troppmair, Simon Whiteside, Alain Israel, Ulf R. Rapp, and Thomas Wirth
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4615–4620. Published online 2000 April 11.
PMCID: PMC18281
Association of Escherichia coli ribosomes with the inner membrane requires the signal recognition particle receptor but is independent of the signal recognition particle
Anat A. Herskovits and Eitan Bibi
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4621–4626. Published online 2000 April 18.
PMCID: PMC18282
A biological function for cadmium in marine diatoms
Todd W. Lane and François M. M. Morel
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4627–4631. Published online 2000 April 18.
PMCID: PMC18283
Biophysics
Single-electron reduction of the oxidized state is coupled to proton uptake via the K pathway in Paracoccus denitrificans cytochrome c oxidase
Maarten Ruitenberg, Aimo Kannt, Ernst Bamberg, Bernd Ludwig, Hartmut Michel, and Klaus Fendler
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4632–4636. Published online 2000 April 18.
PMCID: PMC18284
The three-dimensional structure of halorhodopsin to 5 Å by electron crystallography: A new unbending procedure for two-dimensional crystals by using a global reference structure
Edmund R. S. Kunji, Susanne von Gronau, Dieter Oesterhelt, and Richard Henderson
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4637–4642. Published online 2000 April 11.
PMCID: PMC18285
Local and distant protein structural changes on photoisomerization of the retinal in bacteriorhodopsin
Hideki Kandori, Norimichi Kinoshita, Yoichi Yamazaki, Akio Maeda, Yoshinori Shichida, Richard Needleman, Janos K. Lanyi, Marina Bizounok, Judith Herzfeld, Jan Raap, and Johan Lugtenburg
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4643–4648. Published online 2000 April 11.
PMCID: PMC18286
Robust perfect adaptation in bacterial chemotaxis through integral feedback control
Tau-Mu Yi, Yun Huang, Melvin I. Simon, and John Doyle
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4649–4653.
PMCID: PMC18287
Cell Biology
Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation
Daniel R. Ambruso, Cindy Knall, Amy N. Abell, Julie Panepinto, Arlet Kurkchubasche, Gail Thurman, Carolina Gonzalez-Aller, Andrew Hiester, Martin deBoer, Ronald J. Harbeck, Ryan Oyer, Gary L. Johnson, and Dirk Roos
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4654–4659. Published online 2000 April 11.
PMCID: PMC18288
mRNA splicing-mediated C-terminal replacement of transcription factor Hac1p is required for efficient activation of the unfolded protein response
Kazutoshi Mori, Naoki Ogawa, Tetsushi Kawahara, Hideki Yanagi, and Takashi Yura
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4660–4665. Published online 2000 April 18.
PMCID: PMC18289
Outer mitochondrial membrane permeability can regulate coupled respiration and cell survival
Matthew G. Vander Heiden, Navdeep S. Chandel, Xiao Xian Li, Paul T. Schumacker, Marco Colombini, and Craig B. Thompson
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4666–4671. Published online 2000 April 18.
PMCID: PMC18290
Protection from nitrosative stress by yeast flavohemoglobin
Limin Liu, Ming Zeng, Alfred Hausladen, Joseph Heitman, and Jonathan S. Stamler
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4672–4676. Published online 2000 April 11.
PMCID: PMC18291
The human papillomavirus type 16 negative regulatory RNA element interacts with three proteins that act at different posttranscriptional levels
Maria D. Koffa, Sheila V. Graham, Yoshio Takagaki, James L. Manley, and J. Barklie Clements
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4677–4682. Published online 2000 April 18.
PMCID: PMC18292
Abnormal spermatogenesis and reduced fertility in transition nuclear protein 1-deficient mice
Y. Eugene Yu, Yun Zhang, Emmanual Unni, Cynthia R. Shirley, Jian M. Deng, Lonnie D. Russell, Michael M. Weil, Richard R. Behringer, and Marvin L. Meistrich
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4683–4688.
PMCID: PMC18293
Progesterone-regulated genes in the ovulation process: ADAMTS-1 and cathepsin L proteases
R. L. Robker, D. L. Russell, L. L. Espey, J. P. Lydon, B. W. O'Malley, and J. S. Richards
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4689–4694. Published online 2000 April 18.
PMCID: PMC18294
Developmental Biology
Special Feature: Evolution of the chordate body plan: New insights from phylogenetic analyses of deuterostome phyla
Chris B. Cameron, James R. Garey, and Billie J. Swalla
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4469–4474.
PMCID: PMC18258
Special Feature: Analysis of a complete homeobox gene repertoire: Implications for the evolution of diversity
Claudia Kappen
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4481–4486.
PMCID: PMC18260
Special Feature: Wnt/Shh interactions regulate ectodermal boundary formation during mammalian tooth development
Lena Sarkar, Martyn Cobourne, Stuart Naylor, Matthew Smalley, Trevor Dale, and Paul T. Sharpe
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4520–4524.
PMCID: PMC18267
Special Feature: Searching for the prototypic eye genetic network: Sine oculis is essential for eye regeneration in planarians
D. Pineda, J. Gonzalez, P. Callaerts, K. Ikeo, W. J. Gehring, and E. Salo
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4525–4529.
PMCID: PMC18268
The mutated human gene encoding hepatocyte nuclear factor 1β inhibits kidney formation in developing Xenopus embryos
Wiltrud Wild, Elke Pogge von Strandmann, Aristotelis Nastos, Sabine Senkel, Anja Lingott-Frieg, Michael Bulman, Coralie Bingham, Sian Ellard, Andrew T. Hattersley, and Gerhart U. Ryffel
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4695–4700. Published online 2000 April 11.
PMCID: PMC18295
Ecology
Evolution of the rodent eosinophil-associated RNase gene family by rapid gene sorting and positive selection
Jianzhi Zhang, Kimberly D. Dyer, and Helene F. Rosenberg
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4701–4706. Published online 2000 April 11.
PMCID: PMC18296
Evolution
Special Feature: Precambrian animal diversity: Putative phosphatized embryos from the Doushantuo Formation of China
Jun-Yuan Chen, Paola Oliveri, Chia-Wei Li, Gui-Qing Zhou, Feng Gao, James W. Hagadorn, Kevin J. Peterson, and Eric H. Davidson
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4457–4462.
PMCID: PMC18256
Special Feature: Evolution of biological complexity
Christoph Adami, Charles Ofria, and Travis C. Collier
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4463–4468.
PMCID: PMC18257
Special Feature: Evolution of the chordate body plan: New insights from phylogenetic analyses of deuterostome phyla
Chris B. Cameron, James R. Garey, and Billie J. Swalla
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4469–4474.
PMCID: PMC18258
Special Feature: Pax gene diversity in the basal cnidarian Acropora millepora (Cnidaria, Anthozoa): Implications for the evolution of the Pax gene family
David J. Miller, David C. Hayward, John S. Reece-Hoyes, Ingo Scholten, Julian Catmull, Walter J. Gehring, Patrick Callaerts, Jill E. Larsen, and Eldon E. Ball
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4475–4480.
PMCID: PMC18259
Special Feature: Quantitative assessment of Hox complex expression in the indirect development of the polychaete annelid Chaetopterus sp.
Kevin J. Peterson, Steven Q. Irvine, R. Andrew Cameron, and Eric H. Davidson
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4487–4492.
PMCID: PMC18261
Special Feature: Evolution of Antp-class genes and differential expression of Hydra Hox/paraHox genes in anterior patterning
Dominique Gauchat, Françoise Mazet, Cédric Berney, Michèl Schummer, Sylvia Kreger, Jan Pawlowski, and Brigitte Galliot
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4493–4498.
PMCID: PMC18262
Special Feature: Caenorhabditis elegans embryonic axial patterning requires two recently discovered posterior-group Hox genes
Kimberly Van Auken, Daniel C. Weaver, Lois G. Edgar, and William B. Wood
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4499–4503.
PMCID: PMC18263
Special Feature: Distinct roles of the homeotic genes Ubx and abd-A in beetle embryonic abdominal appendage development
David L. Lewis, Mark DeCamillis, and Randy L. Bennett
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4504–4509.
PMCID: PMC18264
Special Feature: Implications of the Tribolium Deformed mutant phenotype for the evolution of Hox gene function
Susan Brown, Mark DeCamillis, Karen Gonzalez-Charneco, Margaret Denell, Richard Beeman, Wensheng Nie, and Robin Denell
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4510–4514.
PMCID: PMC18265
Special Feature: Expression patterns of hairy, even-skipped, and runt in the spider Cupiennius salei imply that these genes were segmentation genes in a basal arthropod
Wim G. M. Damen, Mathias Weller, and Diethard Tautz
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4515–4519.
PMCID: PMC18266
Special Feature: Divergence of larval morphology between Drosophila sechellia and its sibling species caused by cis-regulatory evolution of ovo/shaven-baby
Élio Sucena and David L. Stern
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4530–4534.
PMCID: PMC18269
Evolution of the rodent eosinophil-associated RNase gene family by rapid gene sorting and positive selection
Jianzhi Zhang, Kimberly D. Dyer, and Helene F. Rosenberg
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4701–4706. Published online 2000 April 11.
PMCID: PMC18296
Early Cretaceous lineages of monocot flowering plants
Kåre Bremer
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4707–4711. Published online 2000 April 4.
PMCID: PMC18297
Primitive synteny of vertebrate major histocompatibility complex class I and class II genes
Yuko Ohta, Kazuhiko Okamura, E. Churchill McKinney, Simona Bartl, Keiichiro Hashimoto, and Martin F. Flajnik
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4712–4717.
PMCID: PMC18298
Genetics
A recombination hotspot delimits a wild-species quantitative trait locus for tomato sugar content to 484 bp within an invertase gene
Eyal Fridman, Tzili Pleban, and Dani Zamir
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4718–4723.
PMCID: PMC18299
RNA polymerase I transcription factor Rrn3 is functionally conserved between yeast and human
Beth Moorefield, Elizabeth A. Greene, and Ronald H. Reeder
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4724–4729. Published online 2000 April 11.
PMCID: PMC18300
A mutant hunt for defects in membrane protein assembly yields mutations affecting the bacterial signal recognition particle and Sec machinery
Hongping Tian, Dana Boyd, and Jon Beckwith
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4730–4735. Published online 2000 April 18.
PMCID: PMC18301
Prolyl 4-hydroxylase is required for viability and morphogenesis in Caenorhabditis elegans
Lisa Friedman, Joshua J. Higgin, Gary Moulder, Robert Barstead, Ronald T. Raines, and Judith Kimble
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4736–4741.
PMCID: PMC18302
Muir–Torre-like syndrome in Fhit-deficient mice
Louise Y. Y. Fong, Vincenzo Fidanza, Nicola Zanesi, Leslie F. Lock, Linda D. Siracusa, Rita Mancini, Zurab Siprashvili, Michelle Ottey, S. Eric Martin, Teresa Druck, Peter A. McCue, Carlo M. Croce, and Kay Huebner
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4742–4747. Published online 2000 April 11.
PMCID: PMC18303
Hypoxia-inducible factor 1α protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations
Carrie Hayes Sutter, Erik Laughner, and Gregg L. Semenza
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4748–4753. Published online 2000 April 11.
PMCID: PMC18304
Attention deficit/hyperactivity disorder children with a 7-repeat allele of the dopamine receptor D4 gene have extreme behavior but normal performance on critical neuropsychological tests of attention
James Swanson, Jaap Oosterlaan, Michael Murias, Sabrina Schuck, Pamela Flodman, M. Anne Spence, Michael Wasdell, Yuanchun Ding, Han-Chang Chi, Moyra Smith, Miranda Mann, Caryn Carlson, James L. Kennedy, Joseph A. Sergeant, Patrick Leung, Ya-Ping Zhang, Avi Sadeh, Chuansheng Chen, Carol K. Whalen, Kimberley A. Babb, Robert Moyzis, and Michael I. Posner
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4754–4759. Published online 2000 April 18.
PMCID: PMC18305
Immunology
Monitoring CD8 T cell responses to NY-ESO-1: Correlation of humoral and cellular immune responses
Elke Jäger, Yasuhiro Nagata, Sacha Gnjatic, Hisashi Wada, Elisabeth Stockert, Julia Karbach, P. Rod Dunbar, Sang Yull Lee, Achim Jungbluth, Dirk Jäger, Michael Arand, Gerd Ritter, Vincenzo Cerundolo, Bo Dupont, Yao-Tseng Chen, Lloyd J. Old, and Alexander Knuth
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4760–4765.
PMCID: PMC18306
CD4+ T cells derived from B cell-deficient mice inhibit the establishment of peripheral B cell pools
Nicole Baumgarth, Gina C. Jager, Ometa C. Herman, Leonard A. Herzenberg, and Leonore A. Herzenberg
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4766–4771.
PMCID: PMC18307
Lsh, an SNF2/helicase family member, is required for proliferation of mature T lymphocytes
T. M. Geiman and K. Muegge
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4772–4777.
PMCID: PMC18308
Plasticity in the organization and sequences of human KIR/ILT gene families
Michael J. Wilson, Michaela Torkar, Anja Haude, Sarah Milne, Tania Jones, Denise Sheer, Stephan Beck, and John Trowsdale
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4778–4783. Published online 2000 April 18.
PMCID: PMC18309
Identification of progenitor cells in long-term spleen stromal cultures that produce immature dendritic cells
Heather L. Wilson, Keping Ni, and Helen C. O'Neill
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4784–4789. Published online 2000 April 11.
PMCID: PMC18310
Medical Sciences
From the Cover:
Dietary bioflavonoids induce cleavage in the MLL gene and may contribute to infant leukemia
Reiner Strick, Pamela L. Strissel, Susanne Borgers, Steve L. Smith, and Janet D. Rowley
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4790–4795. Published online 2000 April 11.
PMCID: PMC18311
Cytotoxic T cell immunity against telomerase reverse transcriptase in humans
Boris Minev, Jason Hipp, Huseyin Firat, Joseph D. Schmidt, Pierre Langlade-Demoyen, and Maurizio Zanetti
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4796–4801. Published online 2000 April 4.
PMCID: PMC18312
Adenovirus-mediated gene transfer of endostatin in vivo results in high level of transgene expression and inhibition of tumor growth and metastases
Bernhard V. Sauter, Olivier Martinet, Wei-Jian Zhang, John Mandeli, and Savio L. C. Woo
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4802–4807. Published online 2000 April 11.
PMCID: PMC18313
From the Cover:
Discovery of a spermatogenesis stage-specific ornithine decarboxylase antizyme: Antizyme 3
Ivaylo P. Ivanov, Andreas Rohrwasser, Daniel A. Terreros, Raymond F. Gesteland, and John F. Atkins
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4808–4813. Published online 2000 April 18.
PMCID: PMC18314
From the Cover:
l-Amino acid sensing by the extracellular Ca2+-sensing receptor
Arthur D. Conigrave, Stephen J. Quinn, and Edward M. Brown
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4814–4819.
PMCID: PMC18315
Mutations in the tumor suppressors Smad2 and Smad4 inactivate transforming growth factor β signaling by targeting Smads to the ubiquitin–proteasome pathway
Jing Xu and Liliana Attisano
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4820–4825.
PMCID: PMC18316
Conditional expression of a Gi-coupled receptor causes ventricular conduction delay and a lethal cardiomyopathy
Charles H. Redfern, Michael Y. Degtyarev, Andrew T. Kwa, Nathan Salomonis, Nathalie Cotte, Tania Nanevicz, Nick Fidelman, Kavin Desai, Karen Vranizan, Elena K. Lee, Peter Coward, Nila Shah, Janet A. Warrington, Glenn I. Fishman, Daniel Bernstein, Anthony J. Baker, and Bruce R. Conklin
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4826–4831.
PMCID: PMC18317
HIV-1 gp120 and chemokines activate ion channels in primary macrophages through CCR5 and CXCR4 stimulation
Qing-Hua Liu, Darlisha A. Williams, Carrie McManus, Frédéric Baribaud, Robert W. Doms, Dominique Schols, Erik De Clercq, Michael I. Kotlikoff, Ronald G. Collman, and Bruce D. Freedman
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4832–4837. Published online 2000 April 11.
PMCID: PMC18318
Human herpesvirus 8 infections in the Amsterdam Cohort Studies (1984–1997): Analysis of seroconversions to ORF65 and ORF73
Jaap Goudsmit, Neil Renwick, Nicole H. T. M. Dukers, Roel A. Coutinho, Siem Heisterkamp, Margreet Bakker, Thomas F. Schulz, Marion Cornelissen, and Gerrit J. Weverling
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4838–4843.
PMCID: PMC18319
15-Deoxy-Δ12,14-prostaglandin J2 inhibits multiple steps in the NF-κB signaling pathway
Daniel S. Straus, Gabriel Pascual, Mei Li, John S. Welch, Mercedes Ricote, Chin-Hui Hsiang, Lei Lei Sengchanthalangsy, Gourisankar Ghosh, and Christopher K. Glass
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4844–4849.
PMCID: PMC18320
Microbiology
Development of an extrachromosomal cloning vector system for use in Borrelia burgdorferi
Marina Sartakova, Elena Dobrikova, and Felipe C. Cabello
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4850–4855. Published online 2000 April 18.
PMCID: PMC18321
The Pseudomonas syringae Hrp pathogenicity island has a tripartite mosaic structure composed of a cluster of type III secretion genes bounded by exchangeable effector and conserved effector loci that contribute to parasitic fitness and pathogenicity in plants
James R. Alfano, Amy O. Charkowski, Wen-Ling Deng, Jorge L. Badel, Tanja Petnicki-Ocwieja, Karin van Dijk, and Alan Collmer
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4856–4861.
PMCID: PMC18322
Adeno-associated virus site-specifically integrates into a muscle-specific DNA region
Nathalie Dutheil, Fabiao Shi, Thierry Dupressoir, and R. Michael Linden
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4862–4866. Published online 2000 April 11.
PMCID: PMC18323
The murine homolog of human Nectin1δ serves as a species nonspecific mediator for entry of human and animal αherpesviruses in a pathway independent of a detectable binding to gD
Laura Menotti, Marc Lopez, Elisa Avitabile, Alessandra Stefan, Francesca Cocchi, Jose Adelaide, Eric Lecocq, Patrice Dubreuil, and Gabriella Campadelli-Fiume
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4867–4872.
PMCID: PMC18324
A self-recombining bacterial artificial chromosome and its application for analysis of herpesvirus pathogenesis
Gregory A. Smith and Lynn W. Enquist
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4873–4878. Published online 2000 April 18.
PMCID: PMC18325
Genome-wide analysis of vaccinia virus protein–protein interactions
Stephen McCraith, Ted Holtzman, Bernard Moss, and Stanley Fields
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4879–4884. Published online 2000 April 18.
PMCID: PMC18326
Inorganic polyphosphate is needed for swimming, swarming, and twitching motilities of Pseudomonas aeruginosa
M. Harunur Rashid and Arthur Kornberg
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4885–4890. Published online 2000 April 11.
PMCID: PMC18327
Inhibition of the expression of penicillin resistance in Streptococcus pneumoniae by inactivation of cell wall muropeptide branching genes
Sergio R. Filipe and Alexander Tomasz
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4891–4896. Published online 2000 April 4.
PMCID: PMC18328
Neurobiology
Fiber diffraction of synthetic α-synuclein filaments shows amyloid-like cross-β conformation
Louise C. Serpell, John Berriman, Ross Jakes, Michel Goedert, and R. Anthony Crowther
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4897–4902.
PMCID: PMC18329
Prostaglandin D synthase gene is involved in the regulation of non-rapid eye movement sleep
Elena Pinzar, Yoshihide Kanaoka, Takashi Inui, Naomi Eguchi, Yoshihiro Urade, and Osamu Hayaishi
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4903–4907. Published online 2000 April 18.
PMCID: PMC18330
Identification with a recombinant antibody of an inner-ear cytokeratin, a marker for hair-cell differentiation
Janet L. Cyr, Andrea M. Bell, and A. J. Hudspeth
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4908–4913. Published online 2000 April 11.
PMCID: PMC18331
Colocalization and coassembly of two human brain M-type potassium channel subunits that are mutated in epilepsy
Edward C. Cooper, Kenneth D. Aldape, Aviva Abosch, Nicholas M. Barbaro, Mitchel S. Berger, Warwick S. Peacock, Yuh Nung Jan, and Lily Yeh Jan
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4914–4919. Published online 2000 April 18.
PMCID: PMC18332
A decamer duplication in the 3′ region of the BRI gene originates an amyloid peptide that is associated with dementia in a Danish kindred
Ruben Vidal, Tamas Révész, Agueda Rostagno, Eugene Kim, Janice L. Holton, Toke Bek, Marie Bojsen-Møller, Hans Braendgaard, Gordon Plant, Jorge Ghiso, and Blas Frangione
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4920–4925. Published online 2000 April 18.
PMCID: PMC18333
d-Serine is an endogenous ligand for the glycine site of the N-methyl-d-aspartate receptor
Jean-Pierre Mothet, Angèle T. Parent, Herman Wolosker, Roscoe O. Brady, Jr., David J. Linden, Christopher D. Ferris, Michael A. Rogawski, and Solomon H. Snyder
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4926–4931.
PMCID: PMC18334
Brain size does not predict general cognitive ability within families
P. Thomas Schoenemann, Thomas F. Budinger, Vincent M. Sarich, and William S.-Y. Wang
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4932–4937.
PMCID: PMC18335
A synthetic agonist at the orphanin FQ/nociceptin receptor ORL1: Anxiolytic profile in the rat
François Jenck, Juergen Wichmann, Frank M. Dautzenberg, Jean-Luc Moreau, Abdel M. Ouagazzal, James R. Martin, Kenneth Lundstrom, Andrea M. Cesura, Sonia M. Poli, Stephan Roever, Sabine Kolczewski, Geo Adam, and Gavin Kilpatrick
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4938–4943. Published online 2000 April 11.
PMCID: PMC18336
Pharmacology
Potent blockade of sodium channels and protection of brain tissue from ischemia by BIII 890 CL
Adrian J. Carter, Matthias Grauert, Uwe Pschorn, Wolf Dietrich Bechtel, Christina Bartmann-Lindholm, Yusheng Qu, Todd Scheuer, William A. Catterall, and Thomas Weiser
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4944–4949. Published online 2000 April 18.
PMCID: PMC18337
Physiology
Elevated subsarcolemmal Ca2+ in mdx mouse skeletal muscle fibers detected with Ca2+-activated K+ channels
Nora Mallouk, Vincent Jacquemond, and Bruno Allard
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4950–4955.
PMCID: PMC18338
Plant Biology
The molecular physiology of heavy metal transport in the Zn/Cd hyperaccumulator Thlaspi caerulescens
Nicole S. Pence, Paul B. Larsen, Stephen D. Ebbs, Deborah L. D. Letham, Mitch M. Lasat, David F. Garvin, David Eide, and Leon V. Kochian
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4956–4960.
PMCID: PMC18339
A longevity assurance gene homolog of tomato mediates resistance to Alternaria alternata f. sp. lycopersici toxins and fumonisin B1
Bas F. Brandwagt, Laurent A. Mesbah, Frank L. W. Takken, Pascal L. Laurent, Tarcies J. A. Kneppers, Jacques Hille, and H. John J. Nijkamp
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4961–4966.
PMCID: PMC18340
Ca2+ channels at the plasma membrane of stomatal guard cells are activated by hyperpolarization and abscisic acid
David W. A. Hamilton, Adrian Hills, Barbara Köhler, and Michael R. Blatt
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4967–4972. Published online 2000 April 18.
PMCID: PMC18341
Toc34 is a preprotein receptor regulated by GTP and phosphorylation
Natalia Sveshnikova, Jürgen Soll, and Enrico Schleiff
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4973–4978. Published online 2000 April 18.
PMCID: PMC18342
Conserved plant genes with similarity to mammalian de novo DNA methyltransferases
Xiaofeng Cao, Nathan M. Springer, Michael G. Muszynski, Ronald L. Phillips, Shawn Kaeppler, and Steven E. Jacobsen
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4979–4984.
PMCID: PMC18343
Specific and heritable genetic interference by double-stranded RNA in Arabidopsis thaliana
Chiou-Fen Chuang and Elliot M. Meyerowitz
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4985–4990. Published online 2000 April 18.
PMCID: PMC18344
Cadmium and iron transport by members of a plant metal transporter family in Arabidopsis with homology to Nramp genes
Sébastien Thomine, Rongchen Wang, John M. Ward, Nigel M. Crawford, and Julian I. Schroeder
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4991–4996.
PMCID: PMC18345
Psychology
Some transformations of color information from lateral geniculate nucleus to striate cortex
Russell L. De Valois, Nicolas P. Cottaris, Sylvia D. Elfar, Luke E. Mahon, and J. Anthony Wilson
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 4997–5002.
PMCID: PMC18346
Social Sciences
Anthropology
How reliable are human phylogenetic hypotheses?
Mark Collard and Bernard Wood
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 5003–5006.
PMCID: PMC18347
Shared cognitive representations of perceptual and semantic structures of basic colors in Chinese and English
Carmella C. Moore, A. Kimball Romney, and Ti-lien Hsia
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 5007–5010.
PMCID: PMC18348
Corrections
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 5011.
PMCID: PMC55985
Corrects: Robert McDaniel, et al. Multiple genetic modifications of the erythromycin polyketide synthase to produce a library of novel “unnatural” natural products. Proc Natl Acad Sci U S A. 1999 March 2; 96(5): 1846–1851.
Proc Natl Acad Sci U S A. 2000 April 25; 97(9): 5011.
PMCID: PMC55986
Corrects: Jianlin Gong, et al. Activation of antitumor cytotoxic T lymphocytes by fusions of human dendritic cells and breast carcinoma cells. Proc Natl Acad Sci U S A. 2000 March 14; 97(6): 2715–2718.
Other Issues:  previous | next | latest | archive