| | This journal provides immediate access to some articles. From the Academy Chinese–American Frontiers of Science Symposium Introduction to the Chinese–American Frontiers of
Science Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11140. PMCID: PMC34048 Assessing climate impacts Ellen E. Wohl, Roger S. Pulwarty, and Jian Yun Zhang Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11141–11142. PMCID: PMC34049 Data assimilation and its applications Bin Wang, Xiaolei Zou, and Jiang Zhu Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11143–11144. PMCID: PMC34050 Macroscopic phase separation in high-temperature superconductors Hai-Hu Wen Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11145–11146. PMCID: PMC34051 Novel polymers: Molecular to nanoscale order in three dimensions Karen L. Wooley, Jeffrey S. Moore, Chi Wu, and Yulian Yang Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11147–11148. PMCID: PMC34052 Commentaries Sticking together Mary B. Kennedy Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11135–11136. PMCID: PMC34046 DNA damage, DNA repair, cell proliferation, and DNA replication:
How do gene mutations result? J. Patrick O'Neill Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11137–11139. Published online 2000 October 3. PMCID: PMC34047 Physical Sciences Applied Physical Sciences Classes of small-world networks L. A. N. Amaral, A. Scala, M. Barthélémy, and H. E. Stanley Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11149–11152. Published online 2000 September 26. PMCID: PMC17168 Chemistry The case of medium-dependent dual mechanisms for
photoisomerization: One-bond-flip and Hula-Twist Robert S. H. Liu and George S. Hammond Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11153–11158. Published online 2000 October 3. PMCID: PMC17169 Nucleic acid-triggered catalytic drug release Zhaochun Ma and John-Stephen Taylor Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11159–11163. PMCID: PMC17170 Catalytic tempering: A method for sampling rough energy
landscapes by Monte Carlo Gustavo Stolovitzky and B. J. Berne Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11164–11169. PMCID: PMC17171 Intracellular delivery of phosphoinositides and inositol
phosphates using polyamine carriers Shoichiro Ozaki, Daryll B. DeWald, Joseph C. Shope, Jian Chen, and Glenn D. Prestwich Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11286–11291. Published online 2000 September 26. PMCID: PMC17192 Computer Sciences Counting probability distributions: Differential geometry and
model selection In Jae Myung, Vijay Balasubramanian, and Mark A. Pitt Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11170–11175. Published online 2000 September 26. PMCID: PMC17172 Geology Deformation and seismicity of Taiwan Claudio Vita-Finzi Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11176–11180. Published online 2000 October 3. PMCID: PMC17173 From the Cover: New isotopic evidence for chronic lead contamination in the San
Francisco Bay estuary system: Implications for the persistence of past
industrial lead emissions in the biosphere Douglas J. Steding, Charles E. Dunlap, and A. Russell Flegal Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11181–11186. Published online 2000 September 12. PMCID: PMC17174 Physics Single chain spectroscopy of conformational dependence of
conjugated polymer photophysics Thomas Huser, Ming Yan, and Lewis J. Rothberg Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11187–11191. PMCID: PMC17175 Biological Sciences Agricultural Sciences Candidate gene analysis of organ pigmentation loci in
the Solanaceae T. A. Thorup, B. Tanyolac, K. D. Livingstone, S. Popovsky, I. Paran, and Molly Jahn Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11192–11197. PMCID: PMC17176 Biochemistry Induction of ribosomal genes and hepatocyte hypertrophy by
adenovirus-mediated expression of c-Myc in vivo Sunkyu Kim, Qing Li, Chi V. Dang, and Linda A. Lee Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11198–11202. Published online 2000 September 26. PMCID: PMC17177 On the tryptophan residue of smooth muscle myosin that responds
to binding of nucleotide Hirofumi Onishi, Kaoru Konishi, Keigi Fujiwara, Kazuyoshi Hayakawa, Masaru Tanokura, Hugo M. Martinez, and Manuel F. Morales Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11203–11208. Published online 2000 October 3. PMCID: PMC17178 High-affinity ouabain binding by a chimeric gastric
H+,K+-ATPase containing
transmembrane hairpins M3-M4 and M5-M6 of the α1-subunit
of rat Na+,K+-ATPase Jan B. Koenderink, Harm P. H. Hermsen, Herman G. P. Swarts, Peter H. G. M. Willems, and Jan Joep H. H. M. De Pont Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11209–11214. Published online 2000 October 3. PMCID: PMC17179 A biosensor assay for studying ligand-membrane receptor
interactions: Binding of antibodies and HIV-1 Env to
chemokine receptors Trevor L. Hoffman, Gabriela Canziani, Li Jia, Joseph Rucker, and Robert W. Doms Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11215–11220. Published online 2000 September 26. PMCID: PMC17180 Bacteriocin AS-48, a microbial cyclic polypeptide structurally
and functionally related to mammalian NK-lysin Carlos González, Grant M. Langdon, Marta Bruix, Antonio Gálvez, Eva Valdivia, Mercedes Maqueda, and Manuel Rico Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11221–11226. Published online 2000 September 26. PMCID: PMC17181 Plasmid-encoded MucB protein is a DNA polymerase (pol RI)
specialized for lesion bypass in the presence of MucA′,
RecA, and SSB Moshe Goldsmith, Lea Sarov-Blat, and Zvi Livneh Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11227–11231. Published online 2000 October 3. PMCID: PMC17182 Involvement of neurogranin in the modulation of
calcium/calmodulin-dependent protein kinase II, synaptic
plasticity, and spatial learning: A study with knockout mice Jhang Ho Pak, Freesia L. Huang, Junfa Li, Detlef Balschun, Klaus G. Reymann, Chin Chiang, Heiner Westphal, and Kuo-Ping Huang Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11232–11237. Published online 2000 October 3. PMCID: PMC17183 Three conformational states of scallop myosin S1 A. Houdusse, A. G. Szent-Györgyi, and C. Cohen Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11238–11243. Published online 2000 October 3. PMCID: PMC17184 HIV-1 integrase inhibitors that compete with the target DNA
substrate define a unique strand transfer conformation
for integrase Amy S. Espeseth, Peter Felock, Abigail Wolfe, Marc Witmer, Jay Grobler, Neville Anthony, Melissa Egbertson, Jeffrey Y. Melamed, Steve Young, Terence Hamill, James L. Cole, and Daria J. Hazuda Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11244–11249. Published online 2000 October 3. PMCID: PMC17185 Generation of oscillations by the p53-Mdm2 feedback loop: A
theoretical and experimental study Ruth Lev Bar-Or, Ruth Maya, Lee A. Segel, Uri Alon, Arnold J. Levine, and Moshe Oren Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11250–11255. Published online 2000 October 3. PMCID: PMC17186 Increase of androgen-induced cell death and androgen receptor
transactivation by BRCA1 in prostate cancer cells Shuyuan Yeh, Yueh-Chiang Hu, Mujib Rahman, Hui-Kuan Lin, Cheng-Lung Hsu, Huei-Ju Ting, Hong-Yo Kang, and Chawnshang Chang Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11256–11261. Published online 2000 October 3. PMCID: PMC17187 Biophysics Catalytic tempering: A method for sampling rough energy
landscapes by Monte Carlo Gustavo Stolovitzky and B. J. Berne Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11164–11169. PMCID: PMC17171 The state diagram for cell adhesion under flow: Leukocyte rolling
and firm adhesion Kai-Chien Chang, David F. J. Tees, and Daniel A. Hammer Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11262–11267. Published online 2000 September 26. PMCID: PMC17188 Cell Biology Differential role of transcription-coupled repair in UVB-induced
G2 arrest and apoptosis in mouse epidermis Marijke van Oosten, Heggert Rebel, Errol C. Friedberg, Harry van Steeg, Gijsbertus T. J. van der Horst, Henk J. van Kranen, Anja Westerman, Albert A. van Zeeland, Leon H. F. Mullenders, and Frank R. de Gruijl Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11268–11273. Published online 2000 September 26. PMCID: PMC17189 Misregulation of gene expression in primary fibroblasts lacking
poly(ADP-ribose) polymerase Cynthia M. Simbulan-Rosenthal, Danith H. Ly, Dean S. Rosenthal, Genevieve Konopka, RuiBai Luo, Zhao-Qi Wang, Peter G. Schultz, and Mark E. Smulson Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11274–11279. Published online 2000 October 3. PMCID: PMC17190 Intracellular unesterified arachidonic acid
signals apoptosis Yang Cao, A. Terrece Pearman, Guy A. Zimmerman, Thomas M. McIntyre, and Stephen M. Prescott Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11280–11285. Published online 2000 September 26. PMCID: PMC17191 Intracellular delivery of phosphoinositides and inositol
phosphates using polyamine carriers Shoichiro Ozaki, Daryll B. DeWald, Joseph C. Shope, Jian Chen, and Glenn D. Prestwich Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11286–11291. Published online 2000 September 26. PMCID: PMC17192 Distinct cAMP response element-binding protein (CREB) domains
stimulate different steps in a concerted mechanism of
transcription activation Jeong-a Kim, Jingfang Lu, and Patrick G. Quinn Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11292–11296. PMCID: PMC17193 Intercellular delivery of a herpes simplex virus VP22 fusion
protein from cells infected with lentiviral vectors Zhennan Lai, Ina Han, Gregory Zirzow, Roscoe O. Brady, and Jakob Reiser Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11297–11302. PMCID: PMC17194 Developmental Biology Distinct but overlapping roles of histone acetylase PCAF and of
the closely related PCAF-B/GCN5 in mouse embryogenesis Teruo Yamauchi, Jun Yamauchi, Takeshi Kuwata, Tomohiko Tamura, Tsuyoshi Yamashita, Nancy Bae, Heiner Westphal, Keiko Ozato, and Yoshihiro Nakatani Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11303–11306. PMCID: PMC17195 From the Cover: Effects of eight growth factors on the differentiation of cells
derived from human embryonic stem cells Maya Schuldiner, Ofra Yanuka, Joseph Itskovitz-Eldor, Douglas A. Melton, and Nissim Benvenisty Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11307–11312. PMCID: PMC17196 Ecology Chemical defense: Aquatic beetle (Dineutes hornii)
vs. fish (Micropterus salmoides) Thomas Eisner and Daniel J. Aneshansley Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11313–11318. Published online 2000 October 3. PMCID: PMC17197 Evolution Lineage-specific loss and divergence of functionally linked genes
in eukaryotes L. Aravind, Hidemi Watanabe, David J. Lipman, and Eugene V. Koonin Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11319–11324. Published online 2000 October 3. PMCID: PMC17198 Remarkable species diversity in Malagasy mouse lemurs (primates,
Microcebus) Anne D. Yoder, Rodin M. Rasoloarison, Steven M. Goodman, Jodi A. Irwin, Sylvia Atsalis, Matthew J. Ravosa, and Jörg U. Ganzhorn Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11325–11330. Published online 2000 September 26. PMCID: PMC17199 Evidence from sequence-tagged-site markers of a recent
progenitor-derivative species pair in conifers Martin Perron, Daniel J. Perry, Christophe Andalo, and Jean Bousquet Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11331–11336. Published online 2000 October 3. PMCID: PMC17200 Mobile elements and chromosomal evolution in the
virilis group of Drosophila Michael B. Evgen'ev, Helena Zelentsova, Helena Poluectova, George T. Lyozin, Vera Veleikodvorskaja, K. I. Pyatkov, Lev A. Zhivotovsky, and Margaret G. Kidwell Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11337–11342. Published online 2000 October 3. PMCID: PMC17201 Independent adaptation to riverine habitats allowed survival of
ancient cetacean lineages Insa Cassens, Saverio Vicario, Victor G. Waddell, Heather Balchowsky, Daniel Van Belle, Wang Ding, Chen Fan, R. S. Lal Mohan, Paulo C. Simões-Lopes, Ricardo Bastida, Axel Meyer, Michael J. Stanhope, and Michel C. Milinkovitch Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11343–11347. PMCID: PMC17202 Heat shock protein 60 sequence comparisons: Duplications, lateral
transfer, and mitochondrial evolution Samuel Karlin and Luciano Brocchieri Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11348–11353. PMCID: PMC17203 Worldwide DNA sequence variation in a 10-kilobase noncoding
region on human chromosome 22 Zhongming Zhao, Li Jin, Yun-Xin Fu, Michele Ramsay, Trefer Jenkins, Elina Leskinen, Pekka Pamilo, Maria Trexler, Laszlo Patthy, Lynn B. Jorde, Sebastian Ramos-Onsins, Ning Yu, and Wen-Hsiung Li Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11354–11358. Published online 2000 September 26. PMCID: PMC17204 Changes in mitochondrial genetic codes as phylogenetic
characters: Two examples from the flatworms Maximilian J. Telford, Elisabeth A. Herniou, Robert B. Russell, and D. Timothy J. Littlewood Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11359–11364. PMCID: PMC17205 Genetics Werner protein recruits DNA polymerase δ to the nucleolus Anna M. Szekely, Yao-Hui Chen, Chunyu Zhang, Junko Oshima, and Sherman M. Weissman Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11365–11370. PMCID: PMC17206 The expression of adipogenic genes is decreased in obesity and
diabetes mellitus Samuel T. Nadler, Jonathan P. Stoehr, Kathryn L. Schueler, Gene Tanimoto, Brian S. Yandell, and Alan D. Attie Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11371–11376. PMCID: PMC17207 A Ufd2/D4Cole1e chimeric protein and
overexpression of Rbp7 in the slow Wallerian
degeneration (WldS) mouse Laura Conforti, Andrea Tarlton, Till G. A. Mack, Weiqian Mi, E. Anne Buckmaster, Diana Wagner, V. Hugh Perry, and Michael P. Coleman Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11377–11382. PMCID: PMC17208 INAUGURAL ARTICLE by a Recently Elected Academy Member: Global mapping of meiotic recombination hotspots and coldspots in
the yeast Saccharomyces cerevisiaeJennifer L. Gerton, Joseph DeRisi, Robert Shroff, Michael Lichten, Patrick O. Brown, and Thomas D. Petes Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11383–11390. PMCID: PMC17209 From the Cover: Proliferation is necessary for both repair and mutation in
transgenic mouse cells Jason H. Bielas and John A. Heddle Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11391–11396. Published online 2000 September 26. PMCID: PMC17210 Genes identified by an expression screen of the vector mosquito
Anopheles gambiae display differential molecular immune
response to malaria parasites and bacteria Frederick Oduol, Jiannong Xu, Oumou Niaré, Ramya Natarajan, and Kenneth D. Vernick Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11397–11402. Published online 2000 September 26. PMCID: PMC17211 Identification of a functional transposase of the
Tol2 element, an Ac-like element from the
Japanese medaka fish, and its transposition in the zebrafish
germ lineage Koichi Kawakami, Akihiro Shima, and Noriko Kawakami Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11403–11408. PMCID: PMC17212 Telomere fusions caused by mutating the terminal region of
telomeric DNA Michael J. McEachern, Shilpa Iyer, Tracy Boswell Fulton, and Elizabeth H. Blackburn Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11409–11414. Published online 2000 October 3. PMCID: PMC17213 Overexpression of the human VPAC2 receptor in the
suprachiasmatic nucleus alters the circadian phenotype of mice Sanbing Shen, Christopher Spratt, W. John Sheward, Imre Kallo, Katrine West, Christine F. Morrison, Clive W. Coen, Hugh M. Marston, and Anthony J. Harmar Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11575–11580. PMCID: PMC17242 Immunology Evolution of the recombination signal sequences in the Ig
heavy-chain variable region locus of mammals Alexandre Hassanin, Rachel Golub, Susanna M. Lewis, and Gillian E. Wu Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11415–11420. PMCID: PMC17214 RelB nuclear translocation regulates B cell MHC molecule, CD40
expression, and antigen-presenting cell function Brendan J. O'Sullivan, Kelli P. A. MacDonald, Allison R. Pettit, and Ranjeny Thomas Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11421–11426. PMCID: PMC17215 Constitutive expression of a complement-like protein in Toll and
JAK gain-of-function mutants of Drosophila Marie Lagueux, Emmanuel Perrodou, Elena A. Levashina, Maria Capovilla, and Jules A. Hoffmann Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11427–11432. PMCID: PMC17216 Direct enumeration of Borrelia-reactive CD4 T
cells ex vivo by using MHC class II tetramers Abbie L. Meyer, Christina Trollmo, Frances Crawford, Philippa Marrack, Allen C. Steere, Brigitte T. Huber, John Kappler, and David A. Hafler Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11433–11438. Published online 2000 September 26. PMCID: PMC17217 Cloning of a type I cytokine receptor most related to the IL-2
receptor β chain Katsutoshi Ozaki, Kristine Kikly, David Michalovich, Peter R. Young, and Warren J. Leonard Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11439–11444. Published online 2000 October 3. PMCID: PMC17218 IL-2-induced activation-induced cell death is inhibited in IL-15
transgenic mice Joanna Marks-Konczalik, Sigrid Dubois, Jacqueline M. Losi, Helen Sabzevari, Nobuo Yamada, Lionel Feigenbaum, Thomas A. Waldmann, and Yutaka Tagaya Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11445–11450. Published online 2000 October 3. PMCID: PMC17219 Genetic susceptibility to breast cancer: HLA DQB*03032 and HLA
DRB1*11 may represent protective alleles Subhra Chaudhuri, Annaiah Cariappa, Mei Tang, Daphne Bell, Daniel A. Haber, Kurt J. Isselbacher, Dianne Finkelstein, David Forcione, and Shiv Pillai Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11451–11454. PMCID: PMC17220 Immunization against Alzheimer's β-amyloid plaques via EFRH
phage administration Dan Frenkel, Odelia Katz, and Beka Solomon Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11455–11459. PMCID: PMC17221 Hindering auxiliary anchors are potent modulators of peptide
binding and selection by I-Ak class II molecules Robert R. Latek, Shirley J. Petzold, and Emil R. Unanue Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11460–11465. Published online 2000 October 3. PMCID: PMC17222 Medical Sciences Selective CXCR4 antagonism by Tat: Implications for in
vivo expansion of coreceptor use by HIV-1 Hua Xiao, Christine Neuveut, H. Lee Tiffany, Monsef Benkirane, Elizabeth A. Rich, Philip M. Murphy, and Kuan-Teh Jeang Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11466–11471. PMCID: PMC17223 Specific Th2 cells accumulate in the central nervous system of
mice protected against experimental autoimmune encephalomyelitis
by copolymer 1 Rina Aharoni, Dvora Teitelbaum, Orith Leitner, Asher Meshorer, Michael Sela, and Ruth Arnon Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11472–11477. PMCID: PMC17224 Detection of emphysema in rat lungs by using magnetic resonance
measurements of 3He diffusion X. Josette Chen, Laurence W. Hedlund, Harald E. Möller, Mark S. Chawla, Robert R. Maronpot, and G. Allan Johnson Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11478–11481. PMCID: PMC17225 Role of circulating nitrite and
S-nitrosohemoglobin in the regulation of regional blood
flow in humans Mark T. Gladwin, James H. Shelhamer, Alan N. Schechter, Margaret E. Pease-Fye, Myron A. Waclawiw, Julio A. Panza, Frederick P. Ognibene, and Richard O. Cannon, III Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11482–11487. PMCID: PMC17226 Ribozyme rescue of photoreceptor cells in P23H transgenic rats:
Long-term survival and late-stage therapy Matthew M. LaVail, Douglas Yasumura, Michael T. Matthes, Kimberly A. Drenser, John G. Flannery, Alfred S. Lewin, and William W. Hauswirth Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11488–11493. Published online 2000 September 26. PMCID: PMC17227 γ-Tocopherol and its major metabolite, in contrast to
α-tocopherol, inhibit cyclooxygenase activity in macrophages and
epithelial cells Qing Jiang, Ilan Elson-Schwab, Chantal Courtemanche, and Bruce N. Ames Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11494–11499. Published online 2000 September 26. PMCID: PMC17228 Histone H2A-mediated transient cytokine gene delivery induces
efficient antitumor responses in murine neuroblastoma Danuta Balicki, Ralph A. Reisfeld, Ursula Pertl, Ernest Beutler, and Holger N. Lode Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11500–11504. Published online 2000 October 3. PMCID: PMC17229 Microbiology Myxococcus xanthus fibril appendages are essential
for excitation by a phospholipid attractant Daniel B. Kearns, Blakemore D. Campbell, and Lawrence J. Shimkets Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11505–11510. Published online 2000 October 3. PMCID: PMC17230 An alternative interpretation of nanobacteria-induced
biomineralization John O. Cisar, De-Qi Xu, John Thompson, William Swaim, Lan Hu, and Dennis J. Kopecko Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11511–11515. PMCID: PMC17231 Invasion in vitro of mosquito midgut cells by the
malaria parasite proceeds by a conserved mechanism and results in
death of the invaded midgut cells Helge Zieler and James A. Dvorak Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11516–11521. PMCID: PMC17232 A novel pH2 control on the expression of
flagella in the hyperthermophilic strictly hydrogenotrophic
methanarchaeaon Methanococcus jannaschii Biswarup Mukhopadhyay, Eric F. Johnson, and Ralph S. Wolfe Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11522–11527. PMCID: PMC17233 Neurobiology l-Serine and glycine serve as major astroglia-derived
trophic factors for cerebellar Purkinje neurons Shigeki Furuya, Toshihide Tabata, Junya Mitoma, Keiko Yamada, Miwako Yamasaki, Asami Makino, Toshifumi Yamamoto, Masahiko Watanabe, Masanobu Kano, and Yoshio Hirabayashi Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11528–11533. Published online 2000 October 3. PMCID: PMC17234 Powerful anticonvulsant action of IL-1 receptor antagonist on
intracerebral injection and astrocytic overexpression in mice A. Vezzani, D. Moneta, M. Conti, C. Richichi, T. Ravizza, A. De Luigi, M. G. De Simoni, G. Sperk, S. Andell-Jonsson, J. Lundkvist, K. Iverfeldt, and T. Bartfai Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11534–11539. Published online 2000 October 3. PMCID: PMC17235 Induction of photosensitivity in neonatal rat pineal gland Gianluca Tosini, Susan Doyle, Mike Geusz, and Michael Menaker Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11540–11544. Published online 2000 September 26. PMCID: PMC17236 Stimulation of glutamate receptor protein synthesis and membrane
insertion within isolated neuronal dendrites Janet Estee Kacharmina, Christy Job, Peter Crino, and James Eberwine Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11545–11550. PMCID: PMC17237 The endocytic receptor protein LRP also mediates neuronal calcium
signaling via
N-methyl-d-aspartate receptors B. J. Bacskai, M. Q. Xia, D. K. Strickland, G. W. Rebeck, and B. T. Hyman Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11551–11556. Published online 2000 October 3. PMCID: PMC17238 From the Cover: The γ-aminobutyric acid type A (GABAA)
receptor-associated protein (GABARAP) promotes GABAA
receptor clustering and modulates the channel kinetics Li Chen, Hongbing Wang, Stefano Vicini, and Richard W. Olsen Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11557–11562. Published online 2000 September 12. PMCID: PMC17239 Targeted disruption of the galanin gene reduces the number of
sensory neurons and their regenerative capacity Fiona E. Holmes, Sally Mahoney, Von R. King, Andrea Bacon, Niall C. H. Kerr, Vassilis Pachnis, Rory Curtis, John V. Priestley, and David Wynick Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11563–11568. Published online 2000 October 3. PMCID: PMC17240 Galanin regulates the postnatal survival of a subset of basal
forebrain cholinergic neurons Gillian O'Meara, Urania Coumis, Shuang Y. Ma, Jan Kehr, Sally Mahoney, Andrea Bacon, Shelley J. Allen, Fiona Holmes, Ulrika Kahl, Fu H. Wang, Ian R. Kearns, Sven Ove-Ogren, David Dawbarn, Elliott J. Mufson, Ceri Davies, Gerard Dawson, and David Wynick Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11569–11574. Published online 2000 October 3. PMCID: PMC17241 Overexpression of the human VPAC2 receptor in the
suprachiasmatic nucleus alters the circadian phenotype of mice Sanbing Shen, Christopher Spratt, W. John Sheward, Imre Kallo, Katrine West, Christine F. Morrison, Clive W. Coen, Hugh M. Marston, and Anthony J. Harmar Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11575–11580. PMCID: PMC17242 A novel function for serotonin-mediated short-term facilitation
in Aplysia: Conversion of a transient, cell-wide
homosynaptic Hebbian plasticity into a persistent, protein
synthesis-independent synapse-specific enhancement Craig H. Bailey, Maurizio Giustetto, Hiuxiang Zhu, Mary Chen, and Eric R. Kandel Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11581–11586. PMCID: PMC17243 Role of Rab GDP dissociation inhibitor α in regulating
plasticity of hippocampal neurotransmission Hiroyoshi Ishizaki, Jun Miyoshi, Haruyuki Kamiya, Atsushi Togawa, Miki Tanaka, Takuya Sasaki, Katsuaki Endo, Akira Mizoguchi, Seiji Ozawa, and Yoshimi Takai Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11587–11592. PMCID: PMC17244 Presynaptic N-methyl-d-aspartate
receptors at the parallel fiber–Purkinje cell synapse M. Casado, S. Dieudonné, and P. Ascher Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11593–11597. Published online 2000 October 3. PMCID: PMC17245 Sensory neuron-specific sodium channel SNS is abnormally
expressed in the brains of mice with experimental allergic
encephalomyelitis and humans with multiple sclerosis Joel A. Black, Sulayman Dib-Hajj, David Baker, Jia Newcombe, M. Louise Cuzner, and Stephen G. Waxman Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11598–11602. PMCID: PMC17246 Physiology Nongenomic actions of estrogens and xenoestrogens by binding at a
plasma membrane receptor unrelated to estrogen receptor α and
estrogen receptor β Angel Nadal, Ana B. Ropero, Ouahiba Laribi, Marjorie Maillet, Esther Fuentes, and Bernat Soria Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11603–11608. PMCID: PMC17247 Nitric oxide prevents cardiovascular disease and determines
survival in polyglobulic mice overexpressing erythropoietin Frank T. Ruschitzka, Roland H. Wenger, Thomas Stallmach, Thomas Quaschning, Cor de Wit, Klaus Wagner, Ralf Labugger, Malte Kelm, Georg Noll, Thomas Rülicke, Sidney Shaw, Raija L. P. Lindberg, Barbara Rodenwaldt, Hans Lutz, Christian Bauer, Thomas F. Lüscher, and Max Gassmann Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11609–11613. PMCID: PMC17248 The osmolyte xylitol reduces the salt concentration of airway
surface liquid and may enhance bacterial killing Joseph Zabner, Michael P. Seiler, Janice L. Launspach, Philip H. Karp, William R. Kearney, Dwight C. Look, Jeffrey J. Smith, and Michael J. Welsh Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11614–11619. PMCID: PMC17249 Adaptive regulation of intestinal lysine metabolism J. B. van Goudoever, B. Stoll, J. F. Henry, D. G. Burrin, and P. J. Reeds Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11620–11625. Published online 2000 October 3. PMCID: PMC17250 RhoB prenylation is driven by the three carboxyl-terminal
amino acids of the protein: Evidenced in vivo by an
anti-farnesyl cysteine antibody Rudi Baron, Emmanuelle Fourcade, Isabelle Lajoie-Mazenc, Cuider Allal, Bettina Couderc, Ronald Barbaras, Gilles Favre, Jean-Charles Faye, and Anne Pradines Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11626–11631. PMCID: PMC17251 Plant Biology Arabidopsis basic leucine zipper transcription
factors involved in an abscisic acid-dependent signal transduction
pathway under drought and high-salinity conditions Yuichi Uno, Takashi Furihata, Hiroshi Abe, Riichiro Yoshida, Kazuo Shinozaki, and Kazuko Yamaguchi-Shinozaki Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11632–11637. Published online 2000 September 26. PMCID: PMC17252 Rice dwarf mutant d1, which is defective in the
α subunit of the heterotrimeric G protein, affects gibberellin
signal transduction Miyako Ueguchi-Tanaka, Yukiko Fujisawa, Masatomo Kobayashi, Motoyuki Ashikari, Yukimoto Iwasaki, Hidemi Kitano, and Makoto Matsuoka Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11638–11643. PMCID: PMC17253 Cooperative regulation of light-harvesting complex II
phosphorylation via the plastoquinol and ferredoxin-thioredoxin
system in chloroplasts E. Rintamäki, P. Martinsuo, S. Pursiheimo, and E.-M. Aro Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11644–11649. Published online 2000 September 26. PMCID: PMC17254 AGO1, QDE-2, and RDE-1 are related proteins required for
post-transcriptional gene silencing in plants, quelling in
fungi, and RNA interference in animals Mathilde Fagard, Stéphanie Boutet, Jean-Benoit Morel, Catherine Bellini, and Hervé Vaucheret Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11650–11654. Published online 2000 October 3. PMCID: PMC17255 Coordinated plant defense responses in Arabidopsis
revealed by microarray analysis Peer M. Schenk, Kemal Kazan, Iain Wilson, Jonathan P. Anderson, Todd Richmond, Shauna C. Somerville, and John M. Manners Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11655–11660. PMCID: PMC17256 Psychology Genetics and visual attention: Selective deficits in healthy
adult carriers of the 4 allele of the
apolipoprotein E gene Pamela M. Greenwood, Trey Sunderland, Judy L. Friz, and Raja Parasuraman Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11661–11666. PMCID: PMC17257 Social Sciences Psychology Amblyopes see true alignment where normal observers see illusory
tilt Ariella V. Popple and Dennis M. Levi Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11667–11672. PMCID: PMC17258 Corrections Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11673. PMCID: PMC56107 Corrects: Jeff G. Hall, et al. From the Cover: Sensitive detection of DNA polymorphisms by the serial invasive signal amplification reaction. Proc Natl Acad Sci U S A. 2000 July 18; 97(15): 8272–8277. Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11673. PMCID: PMC56108 Corrects: Dapeng Zhou, et al. A β-1,3-N-acetylglucosaminyltransferase with poly-N-acetyllactosamine synthase activity is structurally related to β-1,3-galactosyltransferases. Proc Natl Acad Sci U S A. 1999 January 19; 96(2): 406–411. Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11673. PMCID: PMC56109 Corrects: Karin Jurkat-Rott, et al. Voltage-sensor sodium channel mutations cause hypokalemic
periodic paralysis type 2 by enhanced inactivation and reduced current. Proc Natl Acad Sci U S A. 2000 August 15; 97(17): 9549–9554. Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11673. PMCID: PMC56110 Corrects: Yan Xiang, et al. IL-18 binding and inhibition of interferon γ induction by human poxvirus-encoded proteins. Proc Natl Acad Sci U S A. 1999 September 28; 96(20): 11537–11542. Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11673. PMCID: PMC56111 Corrects: Enamul Huq, et al. GIGANTEA is a nuclear protein involved in phytochrome signaling in Arabidopsis. Proc Natl Acad Sci U S A. 2000 August 15; 97(17): 9789–9794. |