| | This journal provides immediate access to some articles. Commentaries Afrotheria: Plate tectonics meets genomics S. Blair Hedges PMCID: PMC33345 Novel therapies in the search for a cure for Huntington's
disease M. Flint Beal and Philippe Hantraye PMCID: PMC33346 T7 RNA polymerase transcription complex: What you see is not
what you get Konstantin Severinov PMCID: PMC33347 The elusive progesterone receptor in
Xenopus oocytes James L. Maller PMCID: PMC33348 More than one way to go Andrew H. Wyllie and Pierre Golstein PMCID: PMC33349 Prey exchange between a stream and its forested watershed
elevates predator densities in both habitats Mary E. Power PMCID: PMC33350 Cliff swallows and the power of behavioral ecology Lee Alan Dugatkin PMCID: PMC33351 Perspective From the Cover:
Peopling the past: New perspectives on the ancient Maya Cynthia Robin PMCID: PMC33352 From the Cover:
Genetics and the population history of Europe Guido Barbujani and Giorgio Bertorelle PMCID: PMC33353 Physical Sciences Mathematics Oscillator representations and systems of ordinary
differential equations Alberto Parmeggiani and Masato Wakayama PMCID: PMC14538 Statistics Model-based analysis of oligonucleotide arrays: Expression index
computation and outlier detection Cheng Li and Wing Hung Wong PMCID: PMC14539 Biological Sciences Biochemistry 2-Aminopurine fluorescence quenching and lifetimes: Role of
base stacking John M. Jean and Kathleen B. Hall PMCID: PMC14540 Antisense-induced exon skipping and synthesis of dystrophin in
the mdx mouse Christopher J. Mann, Kaite Honeyman, Andy J. Cheng, Tina Ly, Frances Lloyd, Sue Fletcher, Jennifer E. Morgan, Terry A. Partridge, and Stephen D. Wilton PMCID: PMC14541 Activation of Reg gene, a gene for
insulin-producing β-cell regeneration: Poly(ADP-ribose) polymerase
binds Reg promoter and regulates the transcription
by autopoly(ADP-ribosyl)ation Takako Akiyama, Shin Takasawa, Koji Nata, Seiichi Kobayashi, Michiaki Abe, Nausheen J. Shervani, Takayuki Ikeda, Kei Nakagawa, Michiaki Unno, Seiki Matsuno, and Hiroshi Okamoto PMCID: PMC14542 Processive DNA helicase activity of the minichromosome
maintenance proteins 4, 6, and 7 complex requires forked DNA structures Joon-Kyu Lee and Jerard Hurwitz PMCID: PMC14543 An anthelmintic compound, nafuredin, shows selective inhibition
of complex I in helminth mitochondria Satoshi Ōmura, Hiroko Miyadera, Hideaki Ui, Kazuro Shiomi, Yuuichi Yamaguchi, Rokuro Masuma, Tohru Nagamitsu, Daisuke Takano, Toshiaki Sunazuka, Achim Harder, Heinz Kölbl, Michio Namikoshi, Hideto Miyoshi, Kimitoshi Sakamoto, and Kiyoshi Kita PMCID: PMC14544 RNA degradosomes exist in vivo in
Escherichia coli as multicomponent complexes associated
with the cytoplasmic membrane via the N-terminal region of
ribonuclease E Gunn-Guang Liou, Wann-Neng Jane, Stanley N. Cohen, Na-Sheng Lin, and Sue Lin-Chao PMCID: PMC14545 Glutamic and aminoadipic semialdehydes are the main carbonyl
products of metal-catalyzed oxidation of proteins Jesús R. Requena, Chien-Chung Chao, Rodney L. Levine, and Earl R. Stadtman PMCID: PMC14546 Tailoring in vitro evolution for protein affinity
or stability Lutz Jermutus, Annemarie Honegger, Falk Schwesinger, Jozef Hanes, and Andreas Plückthun PMCID: PMC14547 Engineering of a functional human NADH-dependent cytochrome
P450 system Olaf Döhr, Mark J. I. Paine, Thomas Friedberg, Gordon C. K. Roberts, and C. Roland Wolf PMCID: PMC14548 Potent histone deacetylase inhibitors built from trichostatin A
and cyclic tetrapeptide antibiotics including trapoxin Ryohei Furumai, Yasuhiko Komatsu, Norikazu Nishino, Saadi Khochbin, Minoru Yoshida, and Sueharu Horinouchi PMCID: PMC14549 Constitutive arrestin-mediated desensitization of a human
vasopressin receptor mutant associated with nephrogenic
diabetes insipidus Larry S. Barak, Robert H. Oakley, Stéphane A. Laporte, and Marc G. Caron PMCID: PMC14550 Purification, priming, and catalytic acylation of carrier protein
domains in the polyketide synthase and nonribosomal peptidyl
synthetase modules of the HMWP1 subunit of yersiniabactin synthetase Zucai Suo, Claire C. Tseng, and Christopher T. Walsh PMCID: PMC14551 Biophysics INAUGURAL ARTICLE by a Recently Elected Academy Member: An amino acid code for protein folding Jon Rumbley, Linh Hoang, Leland Mayne, and S. Walter Englander PMCID: PMC14552 Cell Biology Human embryonic germ cell derivatives express a broad range of
developmentally distinct markers and proliferate
extensively in vitro Michael J. Shamblott, Joyce Axelman, John W. Littlefield, Paul D. Blumenthal, George R. Huggins, Yan Cui, Linzhao Cheng, and John D. Gearhart PMCID: PMC14553 Disruption of matrix metalloproteinase 2 binding to
integrin αvβ3 by an organic molecule
inhibits angiogenesis and tumor growth in vivo Steve Silletti, Torsten Kessler, Joel Goldberg, Dale L. Boger, and David A. Cheresh PMCID: PMC14554 PKN delays mitotic timing by inhibition of Cdc25C: Possible
involvement of PKN in the regulation of cell division Kazuyo Misaki, Hideyuki Mukai, Chiho Yoshinaga, Kumiko Oishi, Takayuki Isagawa, Mikiko Takahashi, Keita Ohsumi, Takeo Kishimoto, and Yoshitaka Ono PMCID: PMC14555 Identification of Id4 as a regulator of
BRCA1 expression by using a ribozyme-library-based inverse genomics approach Carmela Beger, Leigh N. Pierce, Martin Krüger, Eric G. Marcusson, Joan M. Robbins, Piri Welcsh, Peter J. Welch, Karl Welte, Mary-Claire King, Jack R. Barber, and Flossie Wong-Staal PMCID: PMC14556 A role of the kinase mTOR in cellular transformation induced by
the oncoproteins P3k and Akt Masahiro Aoki, Erik Blazek, and Peter K. Vogt PMCID: PMC14557 Mediation of estrogen mitogenic effect in human breast cancer
MCF-7 cells by PC-cell-derived growth factor
(PCDGF/granulin precursor) Runqing Lu and Ginette Serrero PMCID: PMC14558 Activation of calcium entry in human carcinoma A431 cells by
store depletion and phospholipase C- dependent mechanisms converge
on ICRAC-like calcium channels Elena Kaznacheyeva, Alexander Zubov, Konstantin Gusev, Ilya Bezprozvanny, and Galina N. Mozhayeva PMCID: PMC14559 Urothelial function reconsidered: A role in urinary
protein secretion Fang-Ming Deng, Mingxiao Ding, Robert M. Lavker, and Tung-Tien Sun PMCID: PMC14560 Developmental Biology The chondrogenic transcription factor Sox9 is a target of
signaling by the parathyroid hormone-related peptide in the growth
plate of endochondral bones Wendong Huang, Ung-il Chung, Henry M. Kronenberg, and Benoit de Crombrugghe PMCID: PMC14561 Ecology Reciprocal subsidies: Dynamic interdependence between terrestrial
and aquatic food webs Shigeru Nakano and Masashi Murakami PMCID: PMC14562 Evolution Pericentromeric organization at the fusion point of mouse
Robertsonian translocation chromosomes Silvia Garagna, Nicola Marziliano, Maurizio Zuccotti, Jeremy B. Searle, Ernesto Capanna, and Carlo Alberto Redi PMCID: PMC14563 A multiple-site-specific heteroduplex tracking assay as a tool
for the study of viral population dynamics Wolfgang Resch, Neil Parkin, Erin L. Stuelke, Terri Watkins, and Ronald Swanstrom PMCID: PMC14564 Recombination within natural populations of pathogenic bacteria:
Short-term empirical estimates and long-term phylogenetic consequences Edward J. Feil, Edward C. Holmes, Debra E. Bessen, Man-Suen Chan, Nicholas P. J. Day, Mark C. Enright, Richard Goldstein, Derek W. Hood, Awdhesh Kalia, Catrin E. Moore, Jiaji Zhou, and Brian G. Spratt PMCID: PMC14565 From the Cover:
Protein sequence signatures support the African clade
of mammals Marjon A. M. van Dijk, Ole Madsen, François Catzeflis, Michael J. Stanhope, Wilfried W. de Jong, and Mark Pagel PMCID: PMC14566 Genetics From the Cover:
Genetics and the population history of Europe Guido Barbujani and Giorgio Bertorelle PMCID: PMC33353 Deletion of the p27Kip1 gene
restores normal development in cyclin D1-deficient mice Yan Geng, Qunyan Yu, Ewa Sicinska, Manjusri Das, Roderick T. Bronson, and Piotr Sicinski PMCID: PMC14567 Blocking histone deacetylation in Arabidopsis
induces pleiotropic effects on plant gene regulation and development Lu Tian and Z. Jeffrey Chen PMCID: PMC14568 Multiplex allele-specific target amplification based on PCR
suppression Natalia E. Broude, Lingang Zhang, Karen Woodward, David Englert, and Charles R. Cantor PMCID: PMC14569 Effects of replication termination mutants on chromosome
partitioning in Bacillus subtilis Katherine P. Lemon, Iren Kurtser, and Alan D. Grossman PMCID: PMC14570 Genome-wide analysis of developmental and sex-regulated gene
expression profiles in
Caenorhabditis elegans Min Jiang, Jubin Ryu, Monika Kiraly, Kyle Duke, Valerie Reinke, and Stuart K. Kim PMCID: PMC14571 Impaired adipogenesis and lipolysis in the mouse upon selective
ablation of the retinoid X receptor α mediated by a
tamoxifen-inducible chimeric Cre recombinase (Cre-ERT2)
in adipocytes Takeshi Imai, Ming Jiang, Pierre Chambon, and Daniel Metzger PMCID: PMC14572 Presenilin-mediated transmembrane cleavage is required for Notch
signal transduction in Drosophila Gary Struhl and Iva Greenwald PMCID: PMC14573 Immunology Unusual resistance of ALR/Lt mouse β cells to autoimmune
destruction: Role for β cell-expressed resistance determinants Clayton E. Mathews, Robert T. Graser, Alexei Savinov, David V. Serreze, and Edward H. Leiter PMCID: PMC14574 Costimulation via lymphocyte function-associated antigen 1 in the
absence of CD28 ligation promotes anergy of naïve
CD4+ T cells Jennifer L. Ragazzo, Minette E. Ozaki, Lars Karlsson, Per A. Peterson, and Susan R. Webb PMCID: PMC14575 Medical Sciences Anti-apoptotic signaling by hepatocyte growth
factor/Met via the phosphatidylinositol 3-kinase/Akt
and mitogen-activated protein kinase pathways Guang-Hui Xiao, Michael Jeffers, Alfonso Bellacosa, Yasuhiro Mitsuuchi, George F. Vande Woude, and Joseph R. Testa PMCID: PMC14576 Suppression of HIV replication in the resting CD4+
T cell reservoir by autologous CD8+ T cells:
Implications for the development of therapeutic strategies Tae-Wook Chun, J. Shawn Justement, Susan Moir, Claire W. Hallahan, Linda A. Ehler, Shuying Liu, Mary McLaughlin, Mark Dybul, JoAnn M. Mican, and Anthony S. Fauci PMCID: PMC14577 A mouse model of familial porphyria cutanea tarda John D. Phillips, Laurie K. Jackson, Michaeline Bunting, Michael R. Franklin, Kirk R. Thomas, Joanne E. Levy, Nancy C. Andrews, and James P. Kushner PMCID: PMC14578 HPP1: A transmembrane protein-encoding gene
commonly methylated in colorectal polyps and cancers Joanne Young, Kelli G. Biden, Lisa A. Simms, Phillip Huggard, Rozemary Karamatic, Helen J. Eyre, Grant R. Sutherland, Nirmitha Herath, Melissa Barker, Gregory J. Anderson, David R. Fitzpatrick, Grant A. Ramm, Jeremy R. Jass, and Barbara A. Leggett PMCID: PMC14579 Microbiology From the Cover:
Malaria parasite exit from the host erythrocyte: A two-step
process requiring extraerythrocytic proteolysis Brandy L. Salmon, Anna Oksman, and Daniel E. Goldberg PMCID: PMC14580 Extended lung expression and increased tissue localization of
viral IL-10 with adenoviral gene therapy Rebecca M. Minter, Maria A. Ferry, John E. Rectenwald, F. R. Bahjat, Andreas Oberholzer, Caroline Oberholzer, Drake La Face, Van Tsai, C. M. Iqbal Ahmed, Beth Hutchins, Edward M. Copeland, III, Harold S. Ginsberg, and Lyle L. Moldawer PMCID: PMC14581 A secondary drug resistance mutation of TEM-1 β-lactamase that
suppresses misfolding and aggregation Vera Sideraki, Wanzhi Huang, Timothy Palzkill, and Hiram F. Gilbert PMCID: PMC14582 HrpZPsph from the plant pathogen Pseudomonas
syringae pv. phaseolicola binds to lipid
bilayers and forms an ion-conducting pore
in vitro Justin Lee, Birgit Klüsener, George Tsiamis, Conrad Stevens, Cécile Neyt, Anastasia P. Tampakaki, Nickolas J. Panopoulos, Joachim Nöller, Elmar W. Weiler, Guy R. Cornelis, John W. Mansfield, and Thorsten Nürnberger PMCID: PMC14583 Neurobiology Presynaptic regulation of recurrent excitation by D1 receptors in
prefrontal circuits Wen-Jun Gao, Leonid S. Krimer, and Patricia S. Goldman-Rakic PMCID: PMC14584 Dopamine D1/D5 receptor modulation of excitatory synaptic
inputs to layer V prefrontal cortex neurons Jeremy K. Seamans, Daniel Durstewitz, Brian R. Christie, Charles F. Stevens, and Terrence J. Sejnowski PMCID: PMC14585 Cerebellar neurons lacking complex gangliosides degenerate in the
presence of depolarizing levels of potassium Gusheng Wu, Xin Xie, Zi-Hua Lu, and Robert W. Ledeen PMCID: PMC14586 Multiple neural correlates of detection in the human brain Gordon L. Shulman, John M. Ollinger, Martin Linenweber, Steven E. Petersen, and Maurizio Corbetta PMCID: PMC14587 Action potential propagation in mitral cell lateral dendrites is
decremental and controls recurrent and lateral inhibition in the
mammalian olfactory bulb Troy W. Margrie, Bert Sakmann, and Nathaniel N. Urban PMCID: PMC14588 Direction of motion discrimination after early lesions of striate
cortex (V1) of the macaque monkey Tirin Moore, Hillary R. Rodman, and Charles G. Gross PMCID: PMC14589 Preferential potentiation of fast-releasing synaptic vesicles by
cAMP at the calyx of Held Takeshi Sakaba and Erwin Neher PMCID: PMC14590 Mechanisms governing dendritic γ-aminobutyric acid (GABA)
release in the rat olfactory bulb Jeffry S. Isaacson PMCID: PMC14591 Oligomerization of opioid receptors with
β2-adrenergic receptors: A role in trafficking and
mitogen-activated protein kinase activation B. A. Jordan, N. Trapaidze, I. Gomes, R. Nivarthi, and L. A. Devi PMCID: PMC14592 Physiology Increased sensitivity to thyroid hormone in mice with complete
deficiency of thyroid hormone receptor α Paolo E. Macchia, Yoko Takeuchi, Tomoko Kawai, Kevin Cua, Karine Gauthier, Olivier Chassande, Hisao Seo, Yoshitaka Hayashi, Jacques Samarut, Yoshiharu Murata, Roy E. Weiss, and Samuel Refetoff PMCID: PMC14593 The biological lifetime of nitric oxide: Implications for the
perivascular dynamics of NO and O2 Douglas D. Thomas, Xiaoping Liu, Stephen P. Kantrow, and Jack R. Lancaster, Jr. PMCID: PMC14594 Three distinct types of GnRH receptor characterized in
the bullfrog Li Wang, Jan Bogerd, Hueng S. Choi, Jae Y. Seong, Jae M. Soh, Sang Y. Chun, Marion Blomenröhr, Brigitte E. Troskie, Robert P. Millar, Wen H. Yu, Samuel M. McCann, and Hyuk B. Kwon PMCID: PMC14595 Plant Biology INAUGURAL ARTICLE by a Recently Elected Academy Member: Metabolic engineering of plant alkaloid biosynthesis Fumihiko Sato, Takashi Hashimoto, Akira Hachiya, Ken-ichi Tamura, Kum-Boo Choi, Takashi Morishige, Hideki Fujimoto, and Yasuyuki Yamada PMCID: PMC14596 From the Cover:
Negative regulation of defense responses in plants by a
conserved MAPKK kinase Catherine A. Frye, Dingzhong Tang, and Roger W. Innes PMCID: PMC14597 Social Sciences Anthropology From the Cover:
Peopling the past: New perspectives on the ancient Maya Cynthia Robin PMCID: PMC33352 From the Cover:
Genetics and the population history of Europe Guido Barbujani and Giorgio Bertorelle PMCID: PMC33353 Correction Proc Natl Acad Sci U S A. 2001 January 2; 98(1): 379. PMCID: PMC55903 Corrects: H.-C. Huang, et al. Regulation of the antioxidant response element by protein kinase
C-mediated phosphorylation of NF-E2-related factor 2. Proc Natl Acad Sci U S A. 2000 November 7; 97(23): 12475–12480. |
