| | This journal provides immediate access to some articles. In This Issue Proc Natl Acad Sci U S A. 2005 March 29; 102(13): 4657–4658. doi: 10.1073/iti1305102.PMCID: PMC555717 Commentaries Catching RNA polymerase in the act of binding: Intermediates in transcription illuminated by synchrotron footprinting Michael Brenowitz, Dorothy A. Erie, and Mark R. Chance PMCID: PMC555728 Sumoylation: A new wrestler in the DNA repair ring Luis Aragón PMCID: PMC555712 Biography INAUGURAL ARTICLE by a Recently Elected Academy Member: Biography of George E. Andrews Regina Nuzzo PMCID: PMC555700 Physical Sciences Applied Physical Sciences Termination of spiral waves during cardiac fibrillation via shock-induced phase resetting Richard A. Gray and Nipon Chattipakorn PMCID: PMC555701 Chemistry From the Cover:
σ-π molecular dielectric multilayers for low-voltage organic thin-film transistors Myung-Han Yoon, Antonio Facchetti, and Tobin J. Marks PMCID: PMC555722 Artificial metalloenzymes based on biotin-avidin technology for the enantioselective reduction of ketones by transfer hydrogenation Christophe Letondor, Nicolas Humbert, and Thomas R. Ward PMCID: PMC555699 Engineering Design principles of chemical penetration enhancers for transdermal drug delivery Pankaj Karande, Amit Jain, Kaitlin Ergun, Vincent Kispersky, and Samir Mitragotri PMCID: PMC555729 Mathematics INAUGURAL ARTICLE by a Recently Elected Academy Member: Partitions with short sequences and mock theta functions George E. Andrews PMCID: PMC555710 Characterizing wildfire regimes in the United States Bruce D. Malamud, James D. A. Millington, and George L. W. Perry PMCID: PMC555719 Biological Sciences Characterizing wildfire regimes in the United States Bruce D. Malamud, James D. A. Millington, and George L. W. Perry PMCID: PMC555719 Applied Biological Sciences A low-molecular-weight compound discovered through virtual database screening inhibits Stat3 function in breast cancer cells Hui Song, Renxiao Wang, Shaomeng Wang, and Jiayuh Lin PMCID: PMC555708 Biochemistry From the Cover:
Real-time characterization of intermediates in the pathway to open complex formation by Escherichia coli RNA polymerase at the T7A1 promoter Bianca Sclavi, Evgeny Zaychikov, Anastasia Rogozina, Ferdinand Walther, Malcolm Buckle, and Hermann Heumann PMCID: PMC555702 Functional complementation of Trypanosoma brucei RNA in vitro editing with recombinant RNA ligase Guanghan Gao, Agda M. Simpson, Xuedong Kang, Kestrel Rogers, Martina Nebohacova, Feng Li, and Larry Simpson PMCID: PMC555718 Protein kinase casein kinase 2 holoenzyme produced ectopically in human cells can be exported to the external side of the cellular membrane Fernando Rodríguez, Catherine C. Allende, and Jorge E. Allende PMCID: PMC555726 Parathyroid hormone decreases renal vitamin D receptor expression in vivo Kevin D. Healy, Janeen L. Vanhooke, Jean M. Prahl, and Hector F. DeLuca PMCID: PMC555704 Biophysics Retrovirus envelope protein complex structure in situ studied by cryo-electron tomography Friedrich Förster, Ohad Medalia, Nathan Zauberman, Wolfgang Baumeister, and Deborah Fass PMCID: PMC555690 Proteins of the S100 family regulate the oligomerization of p53 tumor suppressor Maria Rosario Fernandez-Fernandez, Dmitry B. Veprintsev, and Alan R. Fersht PMCID: PMC555715 Protein folding: The stepwise assembly of foldon units Haripada Maity, Mita Maity, Mallela M. G. Krishna, Leland Mayne, and S. Walter Englander PMCID: PMC555724 Mapping the interaction surface of a membrane protein: Unveiling the conformational switch of phospholamban in calcium pump regulation J. Zamoon, F. Nitu, C. Karim, D. D. Thomas, and G. Veglia PMCID: PMC555693 Molecular crowding enhances native state stability and refolding rates of globular proteins Margaret S. Cheung, Dmitri Klimov, and D. Thirumalai PMCID: PMC555696 Optical switching of dipolar interactions on proteins Tomoyo Sakata, Yuling Yan, and Gerard Marriott PMCID: PMC555691 Enhanced picture of protein-folding intermediates using organic solvents in H/D exchange and quench-flow experiments Chiaki Nishimura, H. Jane Dyson, and Peter E. Wright PMCID: PMC555694 Stochastic simulations of the origins and implications of long-tailed distributions in gene expression Sandeep Krishna, Bidisha Banerjee, T. V. Ramakrishnan, and G. V. Shivashankar PMCID: PMC555697 Cell Biology From the Cover:
A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization Xiaolan Zhao and Günter Blobel PMCID: PMC555716 Developmental Biology Low O2 tensions and the prevention of differentiation of hES cells Toshihiko Ezashi, Padmalaya Das, and R. Michael Roberts PMCID: PMC554750 From the Cover:
Sonic hedgehog and retinoic acid synergistically promote sensory fate specification from bone marrow-derived pluripotent stem cells Takako Kondo, Scott A. Johnson, Mervin C. Yoder, Raymond Romand, and Eri Hashino PMCID: PMC555703 Genetics An initial strategy for the systematic identification of functional elements in the human genome by low-redundancy comparative sequencing Elliott H. Margulies, Jade P. Vinson, NISC Comparative Sequencing Program, Webb Miller, David B. Jaffe, Kerstin Lindblad-Toh, Jean L. Chang, Eric D. Green, Eric S. Lander, James C. Mullikin, and Michele Clamp PMCID: PMC555705 Application of genome-wide expression analysis to human health and disease J. Perren Cobb, Michael N. Mindrinos, Carol Miller-Graziano, Steve E. Calvano, Henry V. Baker, Wenzhong Xiao, Krzysztof Laudanski, Bernard H. Brownstein, Constance M. Elson, Douglas L. Hayden, David N. Herndon, Stephen F. Lowry, Ronald V. Maier, David A. Schoenfeld, Lyle L. Moldawer, Ronald W. Davis, Ronald G. Tompkins, and Inflammation and Host Response to Injury Large-Scale Collaborative Research Program PMCID: PMC555033 From the Cover:
Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function Bernadette Neve, Martin E. Fernandez-Zapico, Vered Ashkenazi-Katalan, Christian Dina, Yasmin H. Hamid, Erik Joly, Emmanuel Vaillant, Yamina Benmezroua, Emmanuelle Durand, Nicolas Bakaher, Valerie Delannoy, Martine Vaxillaire, Tiffany Cook, Geesje M. Dallinga-Thie, Hans Jansen, Marie-Aline Charles, Karine Clément, Pilar Galan, Serge Hercberg, Nicole Helbecque, Guillaume Charpentier, Marc Prentki, Torben Hansen, Oluf Pedersen, Raul Urrutia, Danielle Melloul, and Philippe Froguel PMCID: PMC554843 Identification of the mismatch repair genes PMS2 and MLH1 as p53 target genes by using serial analysis of binding elements Jiguo Chen and Ivan Sadowski PMCID: PMC555698 Immunology Defective B cell responses in the absence of SH2D1A Massimo Morra, Robert A. Barrington, Ana C. Abadia-Molina, Susumo Okamoto, Aimee Julien, Charles Gullo, Anuj Kalsy, Matthew J. Edwards, Gang Chen, Rosanne Spolski, Warren J. Leonard, Brigitte T. Huber, Persephone Borrow, Christine A. Biron, Abhay R. Satoskar, Michael C. Carroll, and Cox Terhorst PMCID: PMC555707 T cell receptor binding kinetics required for T cell activation depend on the density of cognate ligand on the antigen-presenting cell Pablo A. González, Leandro J. Carreño, Daniel Coombs, Jorge E. Mora, Edith Palmieri, Byron Goldstein, Stanley G. Nathenson, and Alexis M. Kalergis PMCID: PMC555720 Human α-defensins neutralize anthrax lethal toxin and protect against its fatal consequences Chun Kim, Nadesan Gajendran, Hans-Willi Mittrücker, Matthias Weiwad, Young-Hwa Song, Robert Hurwitz, Matthias Wilmanns, Gunter Fischer, and Stefan H. E. Kaufmann PMCID: PMC555714 Medical Sciences Enhanced T cell-mediated protection against malaria in human challenges by using the recombinant poxviruses FP9 and modified vaccinia virus Ankara Daniel P. Webster, Susanna Dunachie, Jenni M. Vuola, Tamara Berthoud, Sheila Keating, Stephen M. Laidlaw, Samuel J. McConkey, Ian Poulton, Laura Andrews, Rikke F. Andersen, Philip Bejon, Geoff Butcher, Robert Sinden, Michael A. Skinner, Sarah C. Gilbert, and Adrian V. S. Hill PMCID: PMC555695 Ku70 acetylation mediates neuroblastoma cell death induced by histone deacetylase inhibitors Chitra Subramanian, Anthony W. Opipari, Jr., Xin Bian, Valerie P. Castle, and Roland P. S. Kwok PMCID: PMC555706 CD4+ T cells mediate antibody-independent acquired immunity to pneumococcal colonization Richard Malley, Krzysztof Trzcinski, Amit Srivastava, Claudette M. Thompson, Porter W. Anderson, and Marc Lipsitch PMCID: PMC555733 Regulation of inducible nitric oxide synthase by aggresome formation Katarzyna E. Kolodziejska, Alan R. Burns, Robert H. Moore, David L. Stenoien, and N. Tony Eissa PMCID: PMC555713 Microbiology Molecular identification of potential pathogens in water and air of a hospital therapy pool Largus T. Angenent, Scott T. Kelley, Allison St. Amand, Norman R. Pace, and Mark T. Hernandez PMCID: PMC555732 Pathogen effector protein screening in yeast identifies Legionella factors that interfere with membrane trafficking Nadim Shohdy, Jem A. Efe, Scott D. Emr, and Howard A. Shuman PMCID: PMC555709 Neuroscience Morphometric analysis of lateral ventricles in schizophrenia and healthy controls regarding genetic and disease-specific factors Martin Styner, Jeffrey A. Lieberman, Robert K. McClure, Daniel R. Weinberger, Douglas W. Jones, and Guido Gerig PMCID: PMC555727 Microstimulation reveals specialized subregions for different complex movements in posterior parietal cortex of prosimian galagos Iwona Stepniewska, Pei-Chun Fang, and Jon H. Kaas PMCID: PMC555725 Night blindness and abnormal cone electroretinogram ON responses in patients with mutations in the GRM6 gene encoding mGluR6 Thaddeus P. Dryja, Terri L. McGee, Eliot L. Berson, Gerald A. Fishman, Michael A. Sandberg, Kenneth R. Alexander, Deborah J. Derlacki, and Aruna S. Rajagopalan PMCID: PMC555731 Thyroid hormone can increase estrogen-mediated transcription from a consensus estrogen response element in neuroblastoma cells Xing Zhao, Heather Lorenc, Heather Stephenson, Yunjiao Joy Wang, Dawn Witherspoon, Benita Katzenellenbogen, Donald Pfaff, and Nandini Vasudevan PMCID: PMC555723 Pharmacology Beneficial effects of pomegranate juice on oxidation-sensitive genes and endothelial nitric oxide synthase activity at sites of perturbed shear stress Filomena de Nigris, Sharon Williams-Ignarro, Lilach O. Lerman, Ettore Crimi, Chiara Botti, Gelsomina Mansueto, Francesco P. D'Armiento, Gaetano De Rosa, Vincenzo Sica, Louis J. Ignarro, and Claudio Napoli PMCID: PMC555721 Plant Biology The power of chemical genomics to study the link between endomembrane system components and the gravitropic response Marci Surpin, Marcela Rojas-Pierce, Clay Carter, Glenn R. Hicks, Jacob Vasquez, and Natasha V. Raikhel PMCID: PMC555711 A central role of Arabidopsis thaliana ovate family proteins in networking and subcellular localization of 3-aa loop extension homeodomain proteins Jana Hackbusch, Klaus Richter, Judith Müller, Francesco Salamini, and Joachim F. Uhrig PMCID: PMC555730 Quantification of cyclic and linear flows in plants Pierre Joliot and Anne Joliot PMCID: PMC555692 Social Sciences Social Sciences Methods to improve the detection of mild cognitive impairment William R. Shankle, A. Kimball Romney, Junko Hara, Dennis Fortier, Malcolm B. Dick, James M. Chen, Timothy Chan, and Xijiang Sun PMCID: PMC555034 |
