| | This journal provides immediate access to some articles. In This Issue Proc Natl Acad Sci U S A. 2005 March 8; 102(10): 3525–3526. doi: 10.1073/iti1005102.PMCID: PMC553343 Commentaries Powerful screens for bacterial virulence proteins Kinya Nomura and Sheng Yang He PMCID: PMC553340 Time for chronotherapy? Clock genes dictate sensitivity to cyclophosphamide Carla B. Green PMCID: PMC553324 Mechanism-derived gene expression signatures and predictive biomarkers in clinical oncology Edison T. Liu PMCID: PMC553302 Long-Range Electron Transfer Special Feature Introduction Distant charge transport Harry B. Gray and Jack Halpern PMCID: PMC553342 Perspective Long-range electron transfer Harry B. Gray and Jay R. Winkler PMCID: PMC553296 Long-Range Electron Transfer Special Feature: Wire-like charge transport at near constant bridge energy through fluorene oligomers Randall H. Goldsmith, Louise E. Sinks, Richard F. Kelley, Laura J. Betzen, Wenhao Liu, Emily A. Weiss, Mark A. Ratner, and Michael R. Wasielewski PMCID: PMC553316 From the Cover:
Long-Range Electron Transfer Special Feature: Protein–DNA charge transport: Redox activation of a DNA repair protein by guanine radical Eylon Yavin, Amie K. Boal, Eric D. A. Stemp, Elizabeth M. Boon, Alison L. Livingston, Valerie L. O'Shea, Sheila S. David, and Jacqueline K. Barton PMCID: PMC553321 Long-Range Electron Transfer Special Feature: Protein dynamics and electron transfer: Electronic decoherence and non-Condon effects Spiros S. Skourtis, Ilya A. Balabin, Tsutomu Kawatsu, and David N. Beratan PMCID: PMC553344 Long-Range Electron Transfer Special Feature: Interprotein electron transfer from cytochrome c2 to photosynthetic reaction center: Tunneling across an aqueous interface Osamu Miyashita, Melvin Y. Okamura, and José N. Onuchic PMCID: PMC553326 Long-Range Electron Transfer Special Feature: Differential influence of dynamic processes on forward and reverse electron transfer across a protein-protein interface Brian M. Hoffman, Laura M. Celis, Deborah A. Cull, Ami D. Patel, Jennifer L. Seifert, Korin E. Wheeler, Jingyun Wang, Jiang Yao, Igor V. Kurnikov, and Judith M. Nocek PMCID: PMC553314 Physical Sciences Chemistry Long-Range Electron Transfer Special Feature: Wire-like charge transport at near constant bridge energy through fluorene oligomers Randall H. Goldsmith, Louise E. Sinks, Richard F. Kelley, Laura J. Betzen, Wenhao Liu, Emily A. Weiss, Mark A. Ratner, and Michael R. Wasielewski PMCID: PMC553316 From the Cover:
Long-Range Electron Transfer Special Feature: Protein–DNA charge transport: Redox activation of a DNA repair protein by guanine radical Eylon Yavin, Amie K. Boal, Eric D. A. Stemp, Elizabeth M. Boon, Alison L. Livingston, Valerie L. O'Shea, Sheila S. David, and Jacqueline K. Barton PMCID: PMC553321 Long-Range Electron Transfer Special Feature: Protein dynamics and electron transfer: Electronic decoherence and non-Condon effects Spiros S. Skourtis, Ilya A. Balabin, Tsutomu Kawatsu, and David N. Beratan PMCID: PMC553344 Long-Range Electron Transfer Special Feature: Interprotein electron transfer from cytochrome c2 to photosynthetic reaction center: Tunneling across an aqueous interface Osamu Miyashita, Melvin Y. Okamura, and José N. Onuchic PMCID: PMC553326 Long-Range Electron Transfer Special Feature: Differential influence of dynamic processes on forward and reverse electron transfer across a protein-protein interface Brian M. Hoffman, Laura M. Celis, Deborah A. Cull, Ami D. Patel, Jennifer L. Seifert, Korin E. Wheeler, Jingyun Wang, Jiang Yao, Igor V. Kurnikov, and Judith M. Nocek PMCID: PMC553314 A remarkably effective copper(II)-dipyridylphosphine catalyst system for the asymmetric hydrosilylation of ketones in air Jing Wu, Jian-Xin Ji, and Albert S. C. Chan PMCID: PMC553317 Chemical genomic profiling to identify intracellular targets of a multiplex kinase inhibitor Charles Kung, Denise M. Kenski, Scott H. Dickerson, Russell W. Howson, Lee F. Kuyper, Hiten D. Madhani, and Kevan M. Shokat PMCID: PMC552777 Biological Sciences Anthropology Reciprocal evolution of the cerebellum and neocortex in fossil humans Anne H. Weaver PMCID: PMC553338 Applied Biological Sciences Ultrasensitivity and noise propagation in a synthetic transcriptional cascade Sara Hooshangi, Stephan Thiberge, and Ron Weiss PMCID: PMC552778 Biochemistry From the Cover:
Long-Range Electron Transfer Special Feature: Protein–DNA charge transport: Redox activation of a DNA repair protein by guanine radical Eylon Yavin, Amie K. Boal, Eric D. A. Stemp, Elizabeth M. Boon, Alison L. Livingston, Valerie L. O'Shea, Sheila S. David, and Jacqueline K. Barton PMCID: PMC553321 Chemical genomic profiling to identify intracellular targets of a multiplex kinase inhibitor Charles Kung, Denise M. Kenski, Scott H. Dickerson, Russell W. Howson, Lee F. Kuyper, Hiten D. Madhani, and Kevan M. Shokat PMCID: PMC552777 Delineation of a unique protein–protein interaction site on the surface of the estrogen receptor Eric H. Kong, Nina Heldring, Jan-Åke Gustafsson, Eckardt Treuter, Roderick E. Hubbard, and Ashley C. W. Pike PMCID: PMC553308 Structural and mechanistic analysis of two prolyl endopeptidases: Role of interdomain dynamics in catalysis and specificity Lu Shan, Irimpan I. Mathews, and Chaitan Khosla PMCID: PMC553306 Regulation of heterogenous nuclear ribonucleoprotein A1 transport by phosphorylation in cells stressed by osmotic shock Eric Allemand, Sònia Guil, Michael Myers, Jorge Moscat, Javier F. Cáceres, and Adrian R. Krainer PMCID: PMC553333 Regulation of coactivator complex assembly and function by protein arginine methylation and demethylimination Young-Ho Lee, Scott A. Coonrod, W. Lee Kraus, Mary Anne Jelinek, and Michael R. Stallcup PMCID: PMC553305 A bifunctional DNA repair protein from Ferroplasma acidarmanus exhibits O6-alkylguanine-DNA alkyltransferase and endonuclease V activities Sreenivas Kanugula, Gary T. Pauly, Robert C. Moschel, and Anthony E. Pegg PMCID: PMC553313 Architecture of the bacteriophage T4 primosome: Electron microscopy studies of helicase (gp41) and primase (gp61) Mona T. Norcum, J. Anthony Warrington, Michelle M. Spiering, Faoud T. Ishmael, Michael A. Trakselis, and Stephen J. Benkovic PMCID: PMC553339 Accumulation of miR-155 and BIC RNA in human B cell lymphomas Peggy S. Eis, Wayne Tam, Liping Sun, Amy Chadburn, Zongdong Li, Mario F. Gomez, Elsebet Lund, and James E. Dahlberg PMCID: PMC552785 Biophysics Long-Range Electron Transfer Special Feature: Protein dynamics and electron transfer: Electronic decoherence and non-Condon effects Spiros S. Skourtis, Ilya A. Balabin, Tsutomu Kawatsu, and David N. Beratan PMCID: PMC553344 Long-Range Electron Transfer Special Feature: Interprotein electron transfer from cytochrome c2 to photosynthetic reaction center: Tunneling across an aqueous interface Osamu Miyashita, Melvin Y. Okamura, and José N. Onuchic PMCID: PMC553326 Long-Range Electron Transfer Special Feature: Differential influence of dynamic processes on forward and reverse electron transfer across a protein-protein interface Brian M. Hoffman, Laura M. Celis, Deborah A. Cull, Ami D. Patel, Jennifer L. Seifert, Korin E. Wheeler, Jingyun Wang, Jiang Yao, Igor V. Kurnikov, and Judith M. Nocek PMCID: PMC553314 Proton binding within a membrane protein by a protonated water cluster Florian Garczarek, Leonid S. Brown, Janos K. Lanyi, and Klaus Gerwert PMCID: PMC553315 Small-molecule-mediated stabilization of familial amyotrophic lateral sclerosis-linked superoxide dismutase mutants against unfolding and aggregation Soumya S. Ray, Richard J. Nowak, Robert H. Brown, Jr., and Peter T. Lansbury, Jr. PMCID: PMC553303 DNA twisting flexibility and the formation of sharply looped protein–DNA complexes T. E. Cloutier and J. Widom PMCID: PMC553319 From the Cover:
Global mapping of the protein structure space and application in structure-based inference of protein function Jingtong Hou, Se-Ran Jun, Chao Zhang, and Sung-Hou Kim PMCID: PMC548596 Time-resolved electrometric and optical studies on cytochrome bd suggest a mechanism of electron-proton coupling in the di-heme active site Ilya Belevich, Vitaliy B. Borisov, Jie Zhang, Ke Yang, Alexander A. Konstantinov, Robert B. Gennis, and Michael I. Verkhovsky PMCID: PMC553295 DNA coiled coils J. L. Campos, L. Urpí, T. Sanmartín, C. Gouyette, and J. A. Subirana PMCID: PMC553320 Three-dimensional reconstruction of the dynactin complex by single-particle image analysis J. L. Hodgkinson, C. Peters, S. A. Kuznetsov, and W. Steffen PMCID: PMC553325 Structural polymorphism of the cytoskeleton: A model of linker-assisted filament aggregation Itamar Borukhov, Robijn F. Bruinsma, William M. Gelbart, and Andrea J. Liu PMCID: PMC553289 Cell Biology Disrupting integrin transmembrane domain heterodimerization increases ligand binding affinity, not valency or clustering Bing-Hao Luo, Christopher V. Carman, Junichi Takagi, and Timothy A. Springer PMCID: PMC553322 Matrix metalloproteinase 13 mediates nitric oxide activation of endothelial cell migration Esther López-Rivera, Tania R. Lizarbe, Mónica Martínez-Moreno, José Miguel López-Novoa, Alicia Rodríguez-Barbero, José Rodrigo, Ana Patricia Fernández, Alberto Álvarez-Barrientos, Santiago Lamas, and Carlos Zaragoza PMCID: PMC553299 Nuclear processing and export of microRNAs in Arabidopsis Mee Yeon Park, Gang Wu, Alfredo Gonzalez-Sulser, Hervé Vaucheret, and R. Scott Poethig PMCID: PMC553294 Identification and functional significance of genes regulated by structurally different histone deacetylase inhibitors Melissa J. Peart, Gordon K. Smyth, Ryan K. van Laar, David D. Bowtell, Victoria M. Richon, Paul A. Marks, Andrew J. Holloway, and Ricky W. Johnstone PMCID: PMC552783 Genome-wide transcriptional analysis of flagellar regeneration in Chlamydomonas reinhardtii identifies orthologs of ciliary disease genes Viktor Stolc, Manoj Pratim Samanta, Waraporn Tongprasit, and Wallace F. Marshall PMCID: PMC553310 Developmental Biology Barx2 functions through distinct corepressor classes to regulate hair follicle remodeling Lorin E. Olson, Jie Zhang, Havilah Taylor, David W. Rose, and Michael G. Rosenfeld PMCID: PMC553323 Transdifferentiation of corneal epithelium into epidermis occurs by means of a multistep process triggered by dermal developmental signals David J. Pearton, Ying Yang, and Danielle Dhouailly PMCID: PMC553311 Remodeling of the intestine during metamorphosis of Xenopus laevis Alex M. Schreiber, Liquan Cai, and Donald D. Brown PMCID: PMC553331 Ecology Extinction dynamics in experimental metapopulations Jane Molofsky and Jean-Baptiste Ferdy PMCID: PMC553292 Evolution Termites assess wood size by using vibration signals Theodore A. Evans, Joseph C. S. Lai, Emilie Toledano, Lee McDowall, Sandrine Rakotonarivo, and Michael Lenz PMCID: PMC553312 Genetics From the Cover:
Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival Howard Y. Chang, Dimitry S. A. Nuyten, Julie B. Sneddon, Trevor Hastie, Robert Tibshirani, Therese Sørlie, Hongyue Dai, Yudong D. He, Laura J. van't Veer, Harry Bartelink, Matt van de Rijn, Patrick O. Brown, and Marc J. van de Vijver PMCID: PMC548329 Immunology HLA-restricted epitope identification and detection of functional T cell responses by using MHC–peptide and costimulatory microarrays Jennifer D. Stone, Walter E. Demkowicz, Jr., and Lawrence J. Stern PMCID: PMC553304 From the Cover:
Expression of an additional cathelicidin antimicrobial peptide protects against bacterial skin infection Phillip H. A. Lee, Takaaki Ohtake, Mohamed Zaiou, Masamoto Murakami, Jennifer A. Rudisill, Kenneth H. Lin, and Richard L. Gallo PMCID: PMC549293 Culturing at atmospheric oxygen levels impacts lymphocyte function Kondala R. Atkuri, Leonard A. Herzenberg, and Leonore A. Herzenberg PMCID: PMC553335 Medical Sciences A mouse model for study of systemic HIV-1 infection, antiviral immune responses, and neuroinvasiveness Mary Jane Potash, Wei Chao, Galina Bentsman, Nicolae Paris, Manisha Saini, Jadwiga Nitkiewicz, Paula Belem, Leroy Sharer, Andrew I. Brooks, and David J. Volsky PMCID: PMC553332 Cardiac stem cells delivered intravascularly traverse the vessel barrier, regenerate infarcted myocardium, and improve cardiac function Buddhadeb Dawn, Adam B. Stein, Konrad Urbanek, Marcello Rota, Brian Whang, Raffaella Rastaldo, Daniele Torella, Xian-Liang Tang, Arash Rezazadeh, Jan Kajstura, Annarosa Leri, Greg Hunt, Jai Varma, Sumanth D. Prabhu, Piero Anversa, and Roberto Bolli PMCID: PMC553298 Synthetic analogues of migrastatin that inhibit mammary tumor metastasis in mice Dandan Shan, Lin Chen, Jon T. Njardarson, Christoph Gaul, Xiaojing Ma, Samuel J. Danishefsky, and Xin-Yun Huang PMCID: PMC553334 Identification of combinatorial drug regimens for treatment of Huntington's disease using Drosophila Namita Agrawal, Judit Pallos, Natalia Slepko, Barbara L. Apostol, Laszlo Bodai, Ling-Wen Chang, Ann-Shyn Chiang, Leslie Michels Thompson, and J. Lawrence Marsh PMCID: PMC553288 Regulation of platelet granule exocytosis by S-nitrosylation Craig N. Morrell, Kenji Matsushita, Kelly Chiles, Robert B. Scharpf, Munekazu Yamakuchi, Rebecca J. A. Mason, Wolfgang Bergmeier, Joseph L. Mankowski, William M. Baldwin, III, Nauder Faraday, and Charles J. Lowenstein PMCID: PMC553307 ErbB-3 mediates phosphoinositide 3-kinase activity in gefitinib-sensitive non-small cell lung cancer cell lines Jeffrey A. Engelman, Pasi A. Jänne, Craig Mermel, Joseph Pearlberg, Toru Mukohara, Christina Fleet, Karen Cichowski, Bruce E. Johnson, and Lewis C. Cantley PMCID: PMC553328 Microbiology The CD4 molecule on CD8+ T lymphocytes directly enhances the immune response to viral and cellular antigens Scott G. Kitchen, Jason K. Whitmire, Nicole R. Jones, Zoran Galic, Christina M. R. Kitchen, Rafi Ahmed, and Jerome A. Zack PMCID: PMC553300 Microsatellite instability regulates transcription factor binding and gene expression Patricia Martin, Katherine Makepeace, Stuart A. Hill, Derek W. Hood, and E. Richard Moxon PMCID: PMC553301 Identification of viral genes essential for replication of murine γ-herpesvirus 68 using signature-tagged mutagenesis Moon Jung Song, Seungmin Hwang, Wendy H. Wong, Ting-Ting Wu, Sangmi Lee, Hsiang-I Liao, and Ren Sun PMCID: PMC553290 Neuroscience Intranasal administration of nerve growth factor (NGF) rescues recognition memory deficits in AD11 anti-NGF transgenic mice Roberta De Rosa, Addys Ancheta Garcia, Chiara Braschi, Simona Capsoni, Lamberto Maffei, Nicoletta Berardi, and Antonino Cattaneo PMCID: PMC553297 From the Cover:
Perinatal exposure to nicotine causes deficits associated with a loss of nicotinic receptor function Gary Cohen, Jean-Christophe Roux, Régis Grailhe, Girvan Malcolm, Jean-Pierre Changeux, and Hugo Lagercrantz PMCID: PMC552781 Coupling of the cortical hemodynamic response to cortical and thalamic neuronal activity Anna Devor, Istvan Ulbert, Andrew K. Dunn, Suresh N. Narayanan, Stephanie R. Jones, Mark L. Andermann, David A. Boas, and Anders M. Dale PMCID: PMC550644 Inhibition of NUDEL (nuclear distribution element-like)-oligopeptidase activity by disrupted-in-schizophrenia 1 Mirian A. F. Hayashi, Fernanda C. V. Portaro, Marta F. Bastos, Juliano R. Guerreiro, Vitor Oliveira, Silvia S. Gorrão, Denise V. Tambourgi, Osvaldo A. Sant'Anna, Paul J. Whiting, L. Miguel Camargo, Katsuhiro Konno, Nicholas J. Brandon, and Antonio C. M. Camargo PMCID: PMC553309 Function and regulation of Tumbleweed (RacGAP50C) in neuroblast proliferation and neuronal morphogenesis Ann Y. N. Goldstein, Yuh-Nung Jan, and Liqun Luo PMCID: PMC553341 Automated microscope system for determining factors that predict neuronal fate Montserrat Arrasate and Steven Finkbeiner PMCID: PMC553329 Loss of mitogen-activated protein kinase kinase kinase 4 (MEKK4) results in enhanced apoptosis and defective neural tube development Hongbo Chi, Matthew R. Sarkisian, Pasko Rakic, and Richard A. Flavell PMCID: PMC553336 Seeing the light: Illumination as a contextual cue to color choice behavior in bumblebees R. Beau Lotto and Lars Chittka PMCID: PMC553337 Inactivation of liver X receptor β leads to adult-onset motor neuron degeneration in male mice Sandra Andersson, Nina Gustafsson, Margaret Warner, and Jan-Åke Gustafsson PMCID: PMC553330 Theta oscillations and sensorimotor performance Leslie M. Kay PMCID: PMC553293 Cortical processing of a brightness illusion Anna Wang Roe, Haidong D. Lu, and Chou P. Hung PMCID: PMC552782 Physiology Evidence from renal proximal tubules that  and solute reabsorption are acutely regulated not by pH but by basolateral  and CO 2Yuehan Zhou, Jinhua Zhao, Patrice Bouyer, and Walter F. Boron PMCID: PMC553318 Psychology The time course and specificity of perceptual deterioration Sara C. Mednick, A. Cyrus Arman, and Geoffrey M. Boynton PMCID: PMC553291 Correction Proc Natl Acad Sci U S A. 2005 March 8; 102(10): 3886. Published online 2005 February 23. doi: 10.1073/pnas.0500609102.PMCID: PMC553327 Corrects: Eric Gelhaye, et al. A specific form of thioredoxin h occurs in plant mitochondria and regulates the alternative oxidase. Proc Natl Acad Sci U S A. 2004 October 5; 101(40): 14545–14550. |
