| | Perspectives Is Bayh-Dole Good for Developing Countries? Lessons from the US Experience Anthony D So, Bhaven N Sampat, Arti K Rai, Robert Cook-Deegan, Jerome H Reichman, Robert Weissman, and Amy Kapczynski PMCID: PMC2573936 Editorial PLoS Biology at 5: The Future Is Open Access Theodora Bloom, Christine Ferguson, Liza Gross, Catriona J MacCallum, Jami Milton, Robert Shields, Stephanie Wai, Janelle Weaver, and Liz Williams PMCID: PMC2573938 Synopses A New View of Embryogenesis—Connective Fibers Join the Dance William Mair PMCID: PMC2567000 Brain Growth Receptors Control Lifespan Richard Robinson PMCID: PMC2573943 A Shortcut to Immortality: Rapid Reprogramming with Tissue Cells Liza Gross PMCID: PMC2570422 Rethinking Dams: Pacific Salmon Recovery May Rest on Other Factors Liza Gross PMCID: PMC2573945 Feature Arctic Sentinels: Global mercury emissions have stabilized over the past decade, yet levels in Arctic marine mammals have risen by an order of magnitude. Scientists struggle to explain why. Hannah Hoag PMCID: PMC2570426 Primer Using Both Sides of Your Brain: The Case for Rapid Interhemispheric Switching Marc F Schmidt PMCID: PMC2573940 Seeking Membranes: Positive-Strand RNA Virus Replication Complexes Mark R Denison PMCID: PMC2573941 Stem Cells Have Different Needs for REST Ola Hermanson PMCID: PMC2573942 Research Articles The ECM Moves during Primitive Streak Formation—Computation of ECM Versus Cellular Motion Evan A Zamir, Brenda J Rongish, and Charles D Little PMCID: PMC2567004 An Autonomous Circadian Clock in the Inner Mouse Retina Regulated by Dopamine and GABA Guo-Xiang Ruan, Gregg C Allen, Shin Yamazaki, and Douglas G McMahon PMCID: PMC2567003 Rapid Interhemispheric Switching during Vocal Production in a Songbird Claude Z. H Wang, Joshua A Herbst, Georg B Keller, and Richard H. R Hahnloser PMCID: PMC2567002 The Nucleosome-Remodeling ATPase ISWI Is Regulated by Poly-ADP-Ribosylation Anna Sala, Gaspare La Rocca, Giosalba Burgio, Elena Kotova, Dario Di Gesù, Marianna Collesano, Antonia M. R Ingrassia, Alexei V Tulin, and Davide F. V Corona PMCID: PMC2567001 The Desensitization Gating of the MthK K+ Channel Is Governed by Its Cytoplasmic Amino Terminus Mario Meng-Chiang Kuo, Innokentiy Maslennikov, Brent Molden, and Senyon Choe PMCID: PMC2573919 Global Reorganization of Replication Domains During Embryonic Stem Cell Differentiation Ichiro Hiratani, Tyrone Ryba, Mari Itoh, Tomoki Yokochi, Michaela Schwaiger, Chia-Wei Chang, Yung Lyou, Tim M Townes, Dirk Schübeler, and David M Gilbert PMCID: PMC2561079 The Timing of Differentiation of Adult Hippocampal Neurons Is Crucial for Spatial Memory Stefano Farioli-Vecchioli, Daniele Saraulli, Marco Costanzi, Simone Pacioni, Irene Cinà, Massimiliano Aceti, Laura Micheli, Alberto Bacci, Vincenzo Cestari, and Felice Tirone PMCID: PMC2561078 High Rate of Recent Transposable Element–Induced Adaptation in Drosophila melanogaster Josefa González, Kapa Lenkov, Mikhail Lipatov, J. Michael Macpherson, and Dmitri A Petrov PMCID: PMC2570423 Promotion of Reprogramming to Ground State Pluripotency by Signal Inhibition Jose Silva, Ornella Barrandon, Jennifer Nichols, Jitsutaro Kawaguchi, Thorold W Theunissen, and Austin Smith PMCID: PMC2570424 Brain IGF-1 Receptors Control Mammalian Growth and Lifespan through a Neuroendocrine Mechanism Laurent Kappeler, Carlos De Magalhaes Filho, Joëlle Dupont, Patricia Leneuve, Pascale Cervera, Laurence Périn, Catherine Loudes, Annick Blaise, Rüdiger Klein, Jacques Epelbaum, Yves Le Bouc, and Martin Holzenberger PMCID: PMC2573928 Diverse RNA-Binding Proteins Interact with Functionally Related Sets of RNAs, Suggesting an Extensive Regulatory System Daniel J Hogan, Daniel P Riordan, André P Gerber, Daniel Herschlag, and Patrick O Brown PMCID: PMC2573929 REST Regulates Distinct Transcriptional Networks in Embryonic and Neural Stem Cells Rory Johnson, Christina Hui-leng Teh, Galih Kunarso, Kee Yew Wong, Gopalan Srinivasan, Megan L Cooper, Manuela Volta, Sarah Su-ling Chan, Leonard Lipovich, Steven M Pollard, R. Krishna Murthy Karuturi, Chia-lin Wei, Noel J Buckley, and Lawrence W Stanton PMCID: PMC2573930 Proteomic Profiling of γ-Secretase Substrates and Mapping of Substrate Requirements Matthew L Hemming, Joshua E Elias, Steven P Gygi, and Dennis J Selkoe PMCID: PMC2570425 Profound Context-Dependent Plasticity of Mitral Cell Responses in Olfactory Bulb Wilder Doucette and Diego Restrepo PMCID: PMC2573932 Structural Homeostasis: Compensatory Adjustments of Dendritic Arbor Geometry in Response to Variations of Synaptic Input Marco Tripodi, Jan Felix Evers, Alex Mauss, Michael Bate, and Matthias Landgraf PMCID: PMC2573934 Evolutionary Plasticity of Polycomb/Trithorax Response Elements in
Drosophila Species Arne Hauenschild, Leonie Ringrose, Christina Altmutter, Renato Paro, and Marc Rehmsmeier PMCID: PMC2573935 Survival of Migrating Salmon Smolts in Large Rivers With and Without Dams David W Welch, Erin L Rechisky, Michael C Melnychuk, Aswea D Porter, Carl J Walters, Shaun Clements, Benjamin J Clemens, R. Scott McKinley, and Carl Schreck PMCID: PMC2573937 |
