| | This journal provides immediate access to some articles. This Week in PNAS Proc Natl Acad Sci U S A. 2008 July 22; 105(29): 9847–9848. doi: 10.1073/iti2908105.PMCID: PMC2481339 Commentaries Networking metabolites and diseases Pascal Braun, Edward Rietman, and Marc Vidal PMCID: PMC2481360 Reconstituting plant miRNA biogenesis Jian-Kang Zhu PMCID: PMC2481364 The capillarity picture and the kinetics of one-dimensional protein folding Diego U. Ferreiro and Peter G. Wolynes PMCID: PMC2481373 Perspective How vision begins: An odyssey Dong-Gen Luo, Tian Xue, and King-Wai Yau PMCID: PMC2481352 Physical Sciences Applied Mathematics Conservation and topology of protein interaction networks under duplication-divergence evolution Kirill Evlampiev and Hervé Isambert PMCID: PMC2481380 The finite harmonic oscillator and its associated sequences Shamgar Gurevich, Ronny Hadani, and Nir Sochen PMCID: PMC2481336 Exact subgrid interface correction schemes for elliptic interface problems Jae-Seok Huh and James A. Sethian PMCID: PMC2481355 Applied Physical Sciences From the Cover:
The implications of human metabolic network topology for disease comorbidity D.-S. Lee, J. Park, K. A. Kay, N. A. Christakis, Z. N. Oltvai, and A.-L. Barabási PMCID: PMC2481357 Chemistry The role of nanostructure in the wetting behavior of mixed-monolayer-protected metal nanoparticles A. Centrone, E. Penzo, M. Sharma, J. W. Myerson, A. M. Jackson, N. Marzari, and F. Stellacci PMCID: PMC2453071 Interaction of nitric oxide with a functional model of cytochrome c oxidase James P. Collman, Abhishek Dey, Richard A. Decreau, Ying Yang, Ali Hosseini, Edward I. Solomon, and Todd A. Eberspacher PMCID: PMC2481353 Geology Sterols in a unicellular relative of the metazoans Robin B. Kodner, Roger E. Summons, Ann Pearson, Nicole King, and Andrew H. Knoll PMCID: PMC2481317 Kinetics of amorphous silica dissolution and the paradox of the silica polymorphs Patricia M. Dove, Nizhou Han, Adam F. Wallace, and James J. De Yoreo PMCID: PMC2481359 Mathematics Metric adjusted skew information Frank Hansen PMCID: PMC2481311 Physics Quantum percolation in cuprate high-temperature superconductors J. C. Phillips PMCID: PMC2481346 Sustainability Science Carbon dioxide sequestration in deep-sea basalt David S. Goldberg, Taro Takahashi, and Angela L. Slagle PMCID: PMC2464617 Biological Sciences Agricultural Sciences Transporters of arsenite in rice and their role in arsenic accumulation in rice grain Jian Feng Ma, Naoki Yamaji, Namiki Mitani, Xiao-Yan Xu, Yu-Hong Su, Steve P. McGrath, and Fang-Jie Zhao PMCID: PMC2481375 Biochemistry Replication stalling at unstable inverted repeats: Interplay between DNA hairpins and fork stabilizing proteins Irina Voineagu, Vidhya Narayanan, Kirill S. Lobachev, and Sergei M. Mirkin PMCID: PMC2481305 A βα-barrel built by the combination of fragments from different folds Tanmay A. M. Bharat, Simone Eisenbeis, Kornelius Zeth, and Birte Höcker PMCID: PMC2481348 Flavin-dependent thymidylate synthase X limits chromosomal DNA replication Frédéric Escartin, Stéphane Skouloubris, Ursula Liebl, and Hannu Myllykallio PMCID: PMC2481370 Host cell recognition by the henipaviruses: Crystal structures of the Nipah G attachment glycoprotein and its complex with ephrin-B3 Kai Xu, Kanagalaghatta R. Rajashankar, Yee-Peng Chan, Juha P. Himanen, Christopher C. Broder, and Dimitar B. Nikolov PMCID: PMC2474567 A modified cysteinyl-labeling assay reveals reversible oxidation of protein tyrosine phosphatases in angiomyolipoma cells Benoit Boivin, Sheng Zhang, Jack L. Arbiser, Zhong-Yin Zhang, and Nicholas K. Tonks PMCID: PMC2481340 A protein from the salivary glands of the pea aphid, Acyrthosiphon pisum, is essential in feeding on a host plant Navdeep S. Mutti, Joe Louis, Loretta K. Pappan, Kirk Pappan, Khurshida Begum, Ming-Shun Chen, Yoonseong Park, Neal Dittmer, Jeremy Marshall, John C. Reese, and Gerald R. Reeck PMCID: PMC2481341 From the Cover:
The RNA-binding proteins HYL1 and SE promote accurate in vitro processing of pri-miRNA by DCL1 Zhicheng Dong, Meng-Hsuan Han, and Nina Fedoroff PMCID: PMC2481344 Structures of synthetic O-antigen fragments from serotype 2a Shigella flexneri in complex with a protective monoclonal antibody B. Vulliez-Le Normand, F. A. Saul, A. Phalipon, F. Bélot, C. Guerreiro, L. A. Mulard, and G. A. Bentley PMCID: PMC2481361 Biophysics From the Cover:
Shifting transition states in the unfolding of a large ankyrin repeat protein Nicolas D. Werbeck, Pamela J. E. Rowling, Vasuki R. Chellamuthu, and Laura S. Itzhaki PMCID: PMC2481366 Distinct conformational changes in β-arrestin report biased agonism at seven-transmembrane receptors Arun K. Shukla, Jonathan D. Violin, Erin J. Whalen, Diane Gesty-Palmer, Sudha K. Shenoy, and Robert J. Lefkowitz PMCID: PMC2481318 A synthetic mammalian gene circuit reveals antituberculosis compounds Wilfried Weber, Ronald Schoenmakers, Bettina Keller, Marc Gitzinger, Thomas Grau, Marie Daoud-El Baba, Peter Sander, and Martin Fussenegger PMCID: PMC2481315 Theoretical and experimental demonstration of the importance of specific nonnative interactions in protein folding Arash Zarrine-Afsar, Stefan Wallin, A. Mirela Neculai, Philipp Neudecker, P. Lynne Howell, Alan R. Davidson, and Hue Sun Chan PMCID: PMC2481363 Cell Biology Plasma membranes are poised for activation of raft phase coalescence at physiological temperature Daniel Lingwood, Jonas Ries, Petra Schwille, and Kai Simons PMCID: PMC2481349 The role of microtubule movement in bidirectional organelle transport Igor M. Kulić, André E. X. Brown, Hwajin Kim, Comert Kural, Benjamin Blehm, Paul R. Selvin, Philip C. Nelson, and Vladimir I. Gelfand PMCID: PMC2481308 Developmental Biology Circulating blood cells function as a surveillance system for damaged tissue in Drosophila larvae Daniel T. Babcock, Amanda R. Brock, Greg S. Fish, Yan Wang, Laurent Perrin, Mark A. Krasnow, and Michael J. Galko PMCID: PMC2474562 Ecology Life-history change in disease-ravaged Tasmanian devil populations Menna E. Jones, Andrew Cockburn, Rodrigo Hamede, Clare Hawkins, Heather Hesterman, Shelly Lachish, Diana Mann, Hamish McCallum, and David Pemberton PMCID: PMC2481324 Long-term resistance to simulated climate change in an infertile grassland J. Philip Grime, Jason D. Fridley, Andrew P. Askew, Ken Thompson, John G. Hodgson, and Chris R. Bennett PMCID: PMC2481365 From the Cover:
Male-derived butterfly anti-aphrodisiac mediates induced indirect plant defense Nina E. Fatouros, Colette Broekgaarden, Gabriella Bukovinszkine'Kiss, Joop J. A. van Loon, Roland Mumm, Martinus E. Huigens, Marcel Dicke, and Monika Hilker PMCID: PMC2481310 Evolution Conservation and topology of protein interaction networks under duplication-divergence evolution Kirill Evlampiev and Hervé Isambert PMCID: PMC2481380 Sterols in a unicellular relative of the metazoans Robin B. Kodner, Roger E. Summons, Ann Pearson, Nicole King, and Andrew H. Knoll PMCID: PMC2481317 Modular networks and cumulative impact of lateral transfer in prokaryote genome evolution Tal Dagan, Yael Artzy-Randrup, and William Martin PMCID: PMC2474566 Evolution of an RNP assembly system: A minimal SMN complex facilitates formation of UsnRNPs in Drosophila melanogaster Matthias Kroiss, Jörg Schultz, Julia Wiesner, Ashwin Chari, Albert Sickmann, and Utz Fischer PMCID: PMC2481332 Fine-scale mapping of recombination rate in Drosophila refines its correlation to diversity and divergence Rob J. Kulathinal, Sarah M. Bennett, Courtney L. Fitzpatrick, and Mohamed A. F. Noor PMCID: PMC2481358 Phylogenetic escalation and decline of plant defense strategies Anurag A. Agrawal and Mark Fishbein PMCID: PMC2481309 The ancestral symbiont sensor kinase CSK links photosynthesis with gene expression in chloroplasts Sujith Puthiyaveetil, T. Anthony Kavanagh, Peter Cain, James A. Sullivan, Christine A. Newell, John C. Gray, Colin Robinson, Mark van der Giezen, Matthew B. Rogers, and John F. Allen PMCID: PMC2474565 Genetics Hidden copy number variation in the HapMap population John C. Marioni, Michael White, Simon Tavaré, and Andrew G. Lynch PMCID: PMC2481329 The FHA domain proteins DAWDLE in Arabidopsis and SNIP1 in humans act in small RNA biogenesis Bin Yu, Liu Bi, Binglian Zheng, Lijuan Ji, David Chevalier, Manu Agarwal, Vanitharani Ramachandran, Wanxiang Li, Thierry Lagrange, John C. Walker, and Xuemei Chen PMCID: PMC2481372 uORFs with unusual translational start codons autoregulate expression of eukaryotic ornithine decarboxylase homologs Ivaylo P. Ivanov, Gary Loughran, and John F. Atkins PMCID: PMC2481320 The maternal-effect, selfish genetic element Medea is associated with a composite Tc1 transposon Marcé D. Lorenzen, Andreas Gnirke, Jonathan Margolis, Jeffrey Garnes, Margie Campbell, Jeffrey J. Stuart, Rajat Aggarwal, Stephen Richards, Yoonseong Park, and Richard W. Beeman PMCID: PMC2481321 Immunology Conserved T cell receptor α-chain induces insulin autoantibodies Masakazu Kobayashi, Jean Jasinski, Edwin Liu, Marcella Li, Dongmei Miao, Li Zhang, Liping Yu, Maki Nakayama, and George S. Eisenbarth PMCID: PMC2464615 Structure of UL18, a peptide-binding viral MHC mimic, bound to a host inhibitory receptor Zhiru Yang and Pamela J. Bjorkman PMCID: PMC2465803 CXCR4–CCR5: A couple modulating T cell functions Rita Lucia Contento, Barbara Molon, Cedric Boularan, Tullio Pozzan, Santos Manes, Stefano Marullo, and Antonella Viola PMCID: PMC2481367 Genomic expression profiling of TNF-α-treated BDC2.5 diabetogenic CD4+ T cells Li-Fen Lee, Chih-Jian Lih, Chao-Jen Huang, Thai Cao, Stanley N. Cohen, and Hugh O. McDevitt PMCID: PMC2481314 Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation Yasushi Onishi, Zoltan Fehervari, Tomoyuki Yamaguchi, and Shimon Sakaguchi PMCID: PMC2481354 Preprocalcitonin signal peptide generates a cytotoxic T lymphocyte-defined tumor epitope processed by a proteasome-independent pathway Faten El Hage, Vincent Stroobant, Isabelle Vergnon, Jean-François Baurain, Hamid Echchakir, Vladimir Lazar, Salem Chouaib, Pierre G. Coulie, and Fathia Mami-Chouaib PMCID: PMC2481335 Medical Sciences Quantification of the infectious dose of Leishmania major transmitted to the skin by single sand flies Nicola Kimblin, Nathan Peters, Alain Debrabant, Nagila Secundino, Jackson Egen, Phillip Lawyer, Michael P. Fay, Shaden Kamhawi, and David Sacks PMCID: PMC2481378 Plant-produced idiotype vaccines for the treatment of non-Hodgkin's lymphoma: Safety and immunogenicity in a phase I clinical study A. A. McCormick, S. Reddy, S. J. Reinl, T. I. Cameron, D. K. Czerwinkski, F. Vojdani, K. M. Hanley, S. J. Garger, E. L. White, J. Novak, J. Barrett, R. B. Holtz, D. Tusé, and R. Levy PMCID: PMC2481377 A Cre-loxP-based mouse model for conditional somatic gene expression and knockdown in vivo by using avian retroviral vectors Barbara Seidler, Annegret Schmidt, Ulrich Mayr, Hassan Nakhai, Roland M. Schmid, Günter Schneider, and Dieter Saur PMCID: PMC2481330 A germ-line-selective advantage rather than an increased mutation rate can explain some unexpectedly common human disease mutations Soo-Kyung Choi, Song-Ro Yoon, Peter Calabrese, and Norman Arnheim PMCID: PMC2474563 Microsatellites as EWS/FLI response elements in Ewing's sarcoma Kunal Gangwal, Savita Sankar, Peter C. Hollenhorst, Michelle Kinsey, Stephen C. Haroldsen, Atul A. Shah, Kenneth M. Boucher, W. Scott Watkins, Lynn B. Jorde, Barbara J. Graves, and Stephen L. Lessnick PMCID: PMC2481306 Genomic markers for malignant progression in pulmonary adenocarcinoma with bronchioloalveolar features Sarit Aviel-Ronen, Bradley P. Coe, Suzanne K. Lau, Gilda da Cunha Santos, Chang-Qi Zhu, Dan Strumpf, Igor Jurisica, Wan L. Lam, and Ming-Sound Tsao PMCID: PMC2465804 Glucose controls CREB activity in islet cells via regulated phosphorylation of TORC2 Deidre Jansson, Andy Cheuk-Him Ng, Accalia Fu, Chantal Depatie, Mufida Al Azzabi, and Robert A. Screaton PMCID: PMC2481316 FOXC2 controls Ang-2 expression and modulates angiogenesis, vascular patterning, remodeling, and functions in adipose tissue Yuan Xue, Renhai Cao, Daniel Nilsson, Shaohua Chen, Rickard Westergren, Eva-Maria Hedlund, Cecile Martijn, Lena Rondahl, Per Krauli, Erik Walum, Sven Enerbäck, and Yihai Cao PMCID: PMC2481379 A pathogenic dyskerin mutation impairs proliferation and activates a DNA damage response independent of telomere length in mice Bai-Wei Gu, Monica Bessler, and Philip J. Mason PMCID: PMC2481326 Fc receptor engagement mediates differentiation of cardiac fibroblast precursor cells Sandra B. Haudek, JoAnn Trial, Ying Xia, Damon Gupta, Darrell Pilling, and Mark L. Entman PMCID: PMC2465805 Soluble receptor-mediated selective inhibition of VEGFR and PDGFRβ signaling during physiologic and tumor angiogenesis Frank Kuhnert, Betty Y. Y. Tam, Barbara Sennino, John T. Gray, Jenny Yuan, Angeline Jocson, Nihar R. Nayak, Richard C. Mulligan, Donald M. McDonald, and Calvin J. Kuo PMCID: PMC2474564 Microbiology Listeria monocytogenes multidrug resistance transporters activate a cytosolic surveillance pathway of innate immunity Gregory T. Crimmins, Anat A. Herskovits, Kai Rehder, Kelsey E. Sivick, Peter Lauer, Thomas W. Dubensky, Jr., and Daniel A. Portnoy PMCID: PMC2481368 The relationship between dNTP pool levels and mutagenesis in an Escherichia coli NDP kinase mutant Jared Nordman and Andrew Wright PMCID: PMC2453072 Two isozymes of particulate methane monooxygenase with different methane oxidation kinetics are found in Methylocystis sp. strain SC2 Mohamed Baani and Werner Liesack PMCID: PMC2481331 Respiratory syncytial virus uses a Vps4-independent budding mechanism controlled by Rab11-FIP2 Thomas J. Utley, Nicole A. Ducharme, Vasundhara Varthakavi, Bryan E. Shepherd, Philip J. Santangelo, Michael E. Lindquist, James R. Goldenring, and James E. Crowe, Jr. PMCID: PMC2481327 Amide bonds assemble pili on the surface of bacilli Jonathan M. Budzik, Luciano A. Marraffini, Puneet Souda, Julian P. Whitelegge, Kym F. Faull, and Olaf Schneewind PMCID: PMC2481347 In silico identified CCR4 antagonists target regulatory T cells and exert adjuvant activity in vaccination Jagadeesh Bayry, Elma Z. Tchilian, Matthew N. Davies, Emily K. Forbes, Simon J. Draper, Srini V. Kaveri, Adrian V. S. Hill, Michel D. Kazatchkine, Peter C. L. Beverley, Darren R. Flower, and David F. Tough PMCID: PMC2481334 Neuroscience Identification of a population of sleep-active cerebral cortex neurons Dmitry Gerashchenko, Jonathan P. Wisor, Deirdre Burns, Rebecca K. Reh, Priyattam J. Shiromani, Takeshi Sakurai, Horacio O. de la Iglesia, and Thomas S. Kilduff PMCID: PMC2481371 Widespread spatial integration in primary somatosensory cortex Jamie L. Reed, Pierre Pouget, Hui-Xin Qi, Zhiyi Zhou, Melanie R. Bernard, Mark J. Burish, John Haitas, A. B. Bonds, and Jon H. Kaas PMCID: PMC2481381 Single treatment with RNAi against prion protein rescues early neuronal dysfunction and prolongs survival in mice with prion disease Melanie D. White, Michael Farmer, Ilaria Mirabile, Sebastian Brandner, John Collinge, and Giovanna R. Mallucci PMCID: PMC2474561 RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways Marcel P. van der Brug, Jeff Blackinton, Jayanth Chandran, Ling-Yang Hao, Ashish Lal, Krystyna Mazan-Mamczarz, Jennifer Martindale, Chengsong Xie, Rili Ahmad, Kelly J. Thomas, Alexandra Beilina, J. Raphael Gibbs, Jinhui Ding, Amanda J. Myers, Ming Zhan, Huaibin Cai, Nancy M. Bonini, Myriam Gorospe, and Mark R. Cookson PMCID: PMC2481328 Interneuron activity controls endocannabinoid-mediated presynaptic plasticity through calcineurin Boris D. Heifets, Vivien Chevaleyre, and Pablo E. Castillo PMCID: PMC2481322 Physiology Nitrite reductase activity of myoglobin regulates respiration and cellular viability in myocardial ischemia-reperfusion injury Ulrike B. Hendgen-Cotta, Marc W. Merx, Sruti Shiva, Joel Schmitz, Stefanie Becher, Johann P. Klare, Heinz-Jürgen Steinhoff, Axel Goedecke, Jürgen Schrader, Mark T. Gladwin, Malte Kelm, and Tienush Rassaf PMCID: PMC2481313 Plant Biology Proteome-wide characterization of sugarbeet seed vigor and its tissue specific expression Julie Catusse, Jean-Marc Strub, Claudette Job, Alain Van Dorsselaer, and Dominique Job PMCID: PMC2474813 Social Sciences Psychology From the Cover:
Conceptual knowledge increases infants' memory capacity Lisa Feigenson and Justin Halberda PMCID: PMC2464616 Corrections Correction for Stach et al., Embryology of a planktonic tunicate reveals traces of sessility PMCID: PMC2481362 Corrects: Thomas Stach, et al. Embryology of a planktonic tunicate reveals traces of sessility. Proc Natl Acad Sci U S A. 2008 May 20; 105(20): 7229–7234. Correction for Catz et al., Cerebellar-dependent motor learning is based on pruning a Purkinje cell population response PMCID: PMC2481351 Corrects: Nicolas Catz, et al. Cerebellar-dependent motor learning is based on pruning a Purkinje cell population response. Proc Natl Acad Sci U S A. 2008 May 20; 105(20): 7309–7314. |
