| | This journal provides immediate access to some articles. Letters Are king penguin populations threatened by Southern Ocean warming? Christophe Barbraud, Henri Weimerskirch, Charles-André Bost, Jaume Forcada, Phil Trathan, and David Ainley PMCID: PMC2449382 Reply to Barbraud et al.: King penguin population threatened by Southern Ocean warming Céline Le Bohec, Joël M. Durant, Michel Gauthier-Clerc, Nils Chr. Stenseth, Young-Hyang Park, Roger Pradel, David Grémillet, Jean-Paul Gendner, and Yvon Le Maho PMCID: PMC2449383 This Week in PNAS Proc Natl Acad Sci U S A. 2008 July 1; 105(26): 8803–8804. doi: 10.1073/iti2608105.PMCID: PMC2449319 Commentaries A Korarchaeote yields to genome sequencing Ken Nealson PMCID: PMC2449320 Viral destruction of cell surface receptors Andrew D. Mesecar and Kiira Ratia PMCID: PMC2449321 Corticotropin-releasing factor, neuroplasticity (sensitization), and alcoholism George F. Koob PMCID: PMC2449322 Physical Sciences Applied Physical Sciences Helical twist controls the thickness of F-actin bundles M. M. A. E. Claessens, C. Semmrich, L. Ramos, and A. R. Bausch PMCID: PMC2449323 Astronomy From the Cover:
Is an eclipse described in the Odyssey? Constantino Baikouzis and Marcelo O. Magnasco PMCID: PMC2440358 Chemistry Seminaphthofluorones are a family of water-soluble, low molecular weight, NIR-emitting fluorophores Youjun Yang, Mark Lowry, Xiangyang Xu, Jorge O. Escobedo, Martha Sibrian-Vazquez, Lisa Wong, Corin M. Schowalter, Timothy J. Jensen, Frank R. Fronczek, Isiah M. Warner, and Robert M. Strongin PMCID: PMC2440362 From the Cover:
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen David Plouffe, Achim Brinker, Case McNamara, Kerstin Henson, Nobutaka Kato, Kelli Kuhen, Advait Nagle, Francisco Adrián, Jason T. Matzen, Paul Anderson, Tae-gyu Nam, Nathanael S. Gray, Arnab Chatterjee, Jeff Janes, S. Frank Yan, Richard Trager, Jeremy S. Caldwell, Peter G. Schultz, Yingyao Zhou, and Elizabeth A. Winzeler PMCID: PMC2440361 Engineering Multiphoton fabrication of chemically responsive protein hydrogels for microactuation Bryan Kaehr and Jason B. Shear PMCID: PMC2449329 Physics Fermi pockets and quantum oscillations of the Hall coefficient in high-temperature superconductors Sudip Chakravarty and Hae-Young Kee PMCID: PMC2449326 Biological Sciences Applied Biological Sciences Multiphoton fabrication of chemically responsive protein hydrogels for microactuation Bryan Kaehr and Jason B. Shear PMCID: PMC2449329 Biochemistry Comparative molecular modeling of Anopheles gambiae CYP6Z1, a mosquito P450 capable of metabolizing DDT Ting-Lan Chiu, Zhimou Wen, Sanjeewa G. Rupasinghe, and Mary A. Schuler PMCID: PMC2449330 Photochemistry of retinal chromophore in mouse melanopsin Marquis T. Walker, R. Lane Brown, Thomas W. Cronin, and Phyllis R. Robinson PMCID: PMC2449331 The mechanism of micro-RNA-mediated translation repression is determined by the promoter of the target gene Yi Wen Kong, Ian G. Cannell, Cornelia H. de Moor, Kirsti Hill, Paul G. Garside, Tiffany L. Hamilton, Hedda A. Meijer, Helen C. Dobbyn, Mark Stoneley, Keith A. Spriggs, Anne E. Willis, and Martin Bushell PMCID: PMC2449332 Nucleosome repeat length and linker histone stoichiometry determine chromatin fiber structure Andrew Routh, Sara Sandin, and Daniela Rhodes PMCID: PMC2440727 A purple acidophilic di-ferric DNA ligase from Ferroplasma Manuel Ferrer, Olga V. Golyshina, Ana Beloqui, Lars H. Böttger, José M. Andreu, Julio Polaina, Antonio L. De Lacey, Alfred X. Trautwein, Kenneth N. Timmis, and Peter N. Golyshin PMCID: PMC2438275 The FACT Spt16 “peptidase” domain is a histone H3–H4 binding module Tobias Stuwe, Michael Hothorn, Erwan Lejeune, Vladimir Rybin, Miriam Bortfeld, Klaus Scheffzek, and Andreas G. Ladurner PMCID: PMC2449335 Crystal structure of human thymine DNA glycosylase bound to DNA elucidates sequence-specific mismatch recognition Atanu Maiti, Michael T. Morgan, Edwin Pozharski, and Alexander C. Drohat PMCID: PMC2449336 cis-Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects Katherine S. Lovejoy, Ryan C. Todd, Shuzhong Zhang, Michael S. McCormick, J. Alejandro D'Aquino, Joyce T. Reardon, Aziz Sancar, Kathleen M. Giacomini, and Stephen J. Lippard PMCID: PMC2449337 Communication between subunits critical to DNA binding by hexameric helicase of bacteriophage T7 Seung-Joo Lee, Udi Qimron, and Charles C. Richardson PMCID: PMC2449338 An epoxide hydrolase involved in the biosynthesis of an insect sex attractant and its use to localize the production site Mohatmed Abdel-latief, Leif A. Garbe, Markus Koch, and Joachim Ruther PMCID: PMC2449339 Biophysics Force-generation and dynamic instability of microtubule bundles Liedewij Laan, Julien Husson, E. Laura Munteanu, Jacob W. J. Kerssemakers, and Marileen Dogterom PMCID: PMC2449340 Systematic analysis of nucleation-dependent polymerization reveals new insights into the mechanism of amyloid self-assembly Wei-Feng Xue, Steve W. Homans, and Sheena E. Radford PMCID: PMC2440360 A generative, probabilistic model of local protein structure Wouter Boomsma, Kanti V. Mardia, Charles C. Taylor, Jesper Ferkinghoff-Borg, Anders Krogh, and Thomas Hamelryck PMCID: PMC2440424 The kinesin-1 motor protein is regulated by a direct interaction of its head and tail Kristen A. Dietrich, Charles V. Sindelar, Paul D. Brewer, Kenneth H. Downing, Christine R. Cremo, and Sarah E. Rice PMCID: PMC2449343 Cell Biology Recruitment of Stat1 to chromatin is required for interferon-induced serine phosphorylation of Stat1 transactivation domain Iwona Sadzak, Melanie Schiff, Irene Gattermeier, Reingard Glinitzer, Ines Sauer, Armin Saalmüller, Edward Yang, Barbara Schaljo, and Pavel Kovarik PMCID: PMC2435588 An autocrine axis in the testis that coordinates spermiation and blood–testis barrier restructuring during spermatogenesis Helen H. N. Yan, Dolores D. Mruk, Elissa W. P. Wong, Will M. Lee, and C. Yan Cheng PMCID: PMC2449345 Excess MCM proteins protect human cells from replicative stress by licensing backup origins of replication Arkaitz Ibarra, Etienne Schwob, and Juan Méndez PMCID: PMC2449346 Developmental Biology Remodeling the exocrine pancreas at metamorphosis in Xenopus laevis Sandeep Mukhi, Jinzhe Mao, and Donald D. Brown PMCID: PMC2449347 Central projections of photoreceptor axons originating from ectopic eyes in Drosophila Jason Clements, Zhiyuan Lu, Walter J. Gehring, Ian A. Meinertzhagen, and Patrick Callaerts PMCID: PMC2449348 Ecology The stochastic nature of larval connectivity among nearshore marine populations D. A. Siegel, S. Mitarai, C. J. Costello, S. D. Gaines, B. E. Kendall, R. R. Warner, and K. B. Winters PMCID: PMC2449349 Evolution A unique life history among tetrapods: An annual chameleon living mostly as an egg Kristopher B. Karsten, Laza N. Andriamandimbiarisoa, Stanley F. Fox, and Christopher J. Raxworthy PMCID: PMC2449350 Categorical perception of a natural, multivariate signal: Mating call recognition in túngara frogs A. T. Baugh, K. L. Akre, and M. J. Ryan PMCID: PMC2449351 From the Cover:
Assembly of the cnidarian camera-type eye from vertebrate-like components Zbynek Kozmik, Jana Ruzickova, Kristyna Jonasova, Yoshifumi Matsumoto, Pavel Vopalensky, Iryna Kozmikova, Hynek Strnad, Shoji Kawamura, Joram Piatigorsky, Vaclav Paces, and Cestmir Vlcek PMCID: PMC2449352 Structurally different alleles of the ath-MIR824 microRNA precursor are maintained at high frequency in Arabidopsis thaliana Juliette de Meaux, Jin-Yong Hu, Ute Tartler, and Ulrike Goebel PMCID: PMC2440359 Genetics Acetylation in the globular core of histone H3 on lysine-56 promotes chromatin disassembly during transcriptional activation Stephanie K. Williams, David Truong, and Jessica K. Tyler PMCID: PMC2449354 Identification of the TFII-I family target genes in the vertebrate genome Nyam-Osor Chimge, Aleksandr V. Makeyev, Frank H. Ruddle, and Dashzeveg Bayarsaihan PMCID: PMC2449355 Congenital disease SNPs target lineage specific structural elements in protein kinases Ali Torkamani, Natarajan Kannan, Susan S. Taylor, and Nicholas J. Schork PMCID: PMC2449356 Immunology Differential function of the NACHT-LRR (NLR) members Nod1 and Nod2 in arthritis Leo A. B. Joosten, Bas Heinhuis, Shahla Abdollahi-Roodsaz, Gerben Ferwerda, Lionel LeBourhis, Dana J. Philpott, Marie-Anne Nahori, Calin Popa, Servaas A. Morre, Jos W. M. van der Meer, Stephen E. Girardin, Mihai G. Netea, and Wim B. van den Berg PMCID: PMC2449357 The complement protein properdin binds apoptotic T cells and promotes complement activation and phagocytosis Claudia Kemper, Lynne M. Mitchell, Lijuan Zhang, and Dennis E. Hourcade PMCID: PMC2449358 Affinity maturation of antibodies assisted by in silico modeling Rodrigo Barderas, Johan Desmet, Peter Timmerman, Rob Meloen, and J. Ignacio Casal PMCID: PMC2449359 The Nalp3 inflammasome is essential for the development of silicosis Suzanne L. Cassel, Stephanie C. Eisenbarth, Shankar S. Iyer, Jeffrey J. Sadler, Oscar R. Colegio, Linda A. Tephly, A. Brent Carter, Paul B. Rothman, Richard A. Flavell, and Fayyaz S. Sutterwala PMCID: PMC2449360 IL-6 blockade inhibits the induction of myelin antigen-specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis Satoshi Serada, Minoru Fujimoto, Masahiko Mihara, Nobuo Koike, Yoshiyuki Ohsugi, Shintaro Nomura, Hiroto Yoshida, Teppei Nishikawa, Fumitaka Terabe, Tomoharu Ohkawara, Tsuyoshi Takahashi, Barry Ripley, Akihiro Kimura, Tadamitsu Kishimoto, and Tetsuji Naka PMCID: PMC2449361 Medical Sciences Epigenetic histone H3 lysine 9 methylation in metabolic memory and inflammatory phenotype of vascular smooth muscle cells in diabetes Louisa M. Villeneuve, Marpadga A. Reddy, Linda L. Lanting, Mei Wang, Li Meng, and Rama Natarajan PMCID: PMC2449362 Topoisomerase levels determine chemotherapy response in vitro and in vivo Darren J. Burgess, Jason Doles, Lars Zender, Wen Xue, Beicong Ma, W. Richard McCombie, Gregory J. Hannon, Scott W. Lowe, and Michael T. Hemann PMCID: PMC2435590 Microbiology From the Cover:
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen David Plouffe, Achim Brinker, Case McNamara, Kerstin Henson, Nobutaka Kato, Kelli Kuhen, Advait Nagle, Francisco Adrián, Jason T. Matzen, Paul Anderson, Tae-gyu Nam, Nathanael S. Gray, Arnab Chatterjee, Jeff Janes, S. Frank Yan, Richard Trager, Jeremy S. Caldwell, Peter G. Schultz, Yingyao Zhou, and Elizabeth A. Winzeler PMCID: PMC2440361 Structure of coronavirus hemagglutinin-esterase offers insight into corona and influenza virus evolution Qinghong Zeng, Martijn A. Langereis, Arno L. W. van Vliet, Eric G. Huizinga, and Raoul J. de Groot PMCID: PMC2449365 Neuroscience Spatiotemporal object continuity in human ventral visual cortex Do-Joon Yi, Nicholas B. Turk-Browne, Jonathan I. Flombaum, Min-Shik Kim, Brian J. Scholl, and Marvin M. Chun PMCID: PMC2442124 From the Cover:
Corticotropin-releasing factor-1 receptor involvement in behavioral neuroadaptation to ethanol: A urocortin1-independent mechanism Raúl Pastor, Carrie S. McKinnon, Angela C. Scibelli, Sue Burkhart-Kasch, Cheryl Reed, Andrey E. Ryabinin, Sarah C. Coste, Mary P. Stenzel-Poore, and Tamara J. Phillips PMCID: PMC2449366 Chiral discrimination of the Japanese beetle sex pheromone and a behavioral antagonist by a pheromone-degrading enzyme Yuko Ishida and Walter S. Leal PMCID: PMC2440356 Mammalian-like features of sleep structure in zebra finches Philip Steven Low, Sylvan S. Shank, Terrence J. Sejnowski, and Daniel Margoliash PMCID: PMC2440357 Neuroligin-1 is required for normal expression of LTP and associative fear memory in the amygdala of adult animals Juhyun Kim, Sang-Yong Jung, Yeon Kyung Lee, Sangki Park, June-Seek Choi, C. Justin Lee, Hye-Sun Kim, Yun-Beom Choi, Peter Scheiffele, Craig H. Bailey, Eric R. Kandel, and Joung-Hun Kim PMCID: PMC2449369 An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP Gary A. Wayman, Monika Davare, Hideaki Ando, Dale Fortin, Olga Varlamova, Hai-Ying M. Cheng, Daniel Marks, Karl Obrietan, Thomas R. Soderling, Richard H. Goodman, and Soren Impey PMCID: PMC2449370 Pharmacology Beta-caryophyllene is a dietary cannabinoid Jürg Gertsch, Marco Leonti, Stefan Raduner, Ildiko Racz, Jian-Zhong Chen, Xiang-Qun Xie, Karl-Heinz Altmann, Meliha Karsak, and Andreas Zimmer PMCID: PMC2449371 Physiology Cyclic adenosine monophosphate differentiated β-endorphin neurons promote immune function and prevent prostate cancer growth Dipak K. Sarkar, Nadka I. Boyadjieva, Cui Ping Chen, María Ortigüela, Kenneth Reuhl, E. Michael Clement, Peter Kuhn, and Jason Marano PMCID: PMC2449372 Multimeric nature of voltage-gated proton channels Hans P. Koch, Tatsuki Kurokawa, Yoshifumi Okochi, Mari Sasaki, Yasushi Okamura, and H. Peter Larsson PMCID: PMC2449373 Plant Biology A TCP domain transcription factor controls flower type specification along the radial axis of the Gerbera (Asteraceae) inflorescence Suvi K. Broholm, Sari Tähtiharju, Roosa A. E. Laitinen, Victor A. Albert, Teemu H. Teeri, and Paula Elomaa PMCID: PMC2449374 Intraplastidial trafficking of a phage-type RNA polymerase is mediated by a thylakoid RING-H2 protein Jacinthe Azevedo, Florence Courtois, Mohamed-Ali Hakimi, Emilie Demarsy, Thierry Lagrange, Jean-Pierre Alcaraz, Pankaj Jaiswal, Laurence Maréchal-Drouard, and Silva Lerbs-Mache PMCID: PMC2449375 Social Sciences Psychology Spatiotemporal object continuity in human ventral visual cortex Do-Joon Yi, Nicholas B. Turk-Browne, Jonathan I. Flombaum, Min-Shik Kim, Brian J. Scholl, and Marvin M. Chun PMCID: PMC2442124 From the Cover:
Contextual priming: Where people vote affects how they vote Jonah Berger, Marc Meredith, and S. Christian Wheeler PMCID: PMC2449328 Corrections Correction for Zhang, The drifting human genome PMCID: PMC2449376 Corrects: Jianzhi Zhang. The drifting human genome. Proc Natl Acad Sci U S A. 2007 December 18; 104(51): 20147–20148. Correction for Macdonald and Pike, Heterogeneity in EGF-binding affinities arises from negative cooperativity in an aggregating system PMCID: PMC2449377 Corrects: Jennifer L. Macdonald, et al. Heterogeneity in EGF-binding affinities arises from negative cooperativity in an aggregating system. Proc Natl Acad Sci U S A. 2008 January 8; 105(1): 112–117. Correction for Ames et al., Crystal structure and functional analysis of tetracenomycin ARO/CYC: Implications for cyclization specificity of aromatic polyketides PMCID: PMC2449378 Corrects: Brian Douglas Ames, et al. Crystal structure and functional analysis of tetracenomycin ARO/CYC: Implications for cyclization specificity of aromatic polyketides. Proc Natl Acad Sci U S A. 2008 April 8; 105(14): 5349–5354. Correction for Sun et al., EB1 promotes Aurora-B kinase activity through blocking its inactivation by protein phosphatase 2A PMCID: PMC2449379 Corrects: Lei Sun, et al. EB1 promotes Aurora-B kinase activity through blocking its inactivation by protein phosphatase 2A. Proc Natl Acad Sci U S A. 2008 May 20; 105(20): 7153–7158. Correction for Kannan et al., The hallmark of AGC kinase functional divergence is its C-terminal tail, a cis-acting regulatory module PMCID: PMC2449380 Corrects: Natarajan Kannan, et al. The hallmark of AGC kinase functional divergence is its C-terminal tail, a cis-acting regulatory module. Proc Natl Acad Sci U S A. 2007 January 23; 104(4): 1272–1277. Correction for Pandey and Sassetti, Mycobacterial persistence requires the utilization of host cholesterol PMCID: PMC2449381 Corrects: Amit K. Pandey, et al. Mycobacterial persistence requires the utilization of host cholesterol. Proc Natl Acad Sci U S A. 2008 March 18; 105(11): 4376–4380. |
