| | This journal provides immediate access to some articles. Letters Role of GSK3β in behavioral abnormalities induced by serotonin deficiency R. H. Belmaker, Galila Agam, and Yuly Bersudsky PMCID: PMC2438251 Reply to Belmaker et al.: GSK3β haploinsufficiency results in lithium-like effects in the forced-swim test Jean-Martin Beaulieu, Xiaodong Zhang, Ramona M. Rodriguiz, Tatyana D. Sotnikova, William C. Wetsel, Raul R. Gainetdinov, and Marc G. Caron PMCID: PMC2438252 This Week in PNAS Proc Natl Acad Sci U S A. 2008 May 20; 105(20): 7107–7108. doi: 10.1073/iti2008105.PMCID: PMC2438209 Commentaries Integrins step up the pace of cell migration through polyamines and potassium channels Carol A. Vandenberg PMCID: PMC2438210 A VAST staging area for regulatory proteins Aaron P. Mitchell PMCID: PMC2438211 Are cheetahs on the run from prion-like amyloidosis? Byron Caughey and Gerald S. Baron PMCID: PMC2438212 Physical Sciences Geology High-pressure synthesis of the cubic perovskite BaRuO3 and evolution of ferromagnetism in ARuO3 (A = Ca, Sr, Ba) ruthenates C.-Q. Jin, J.-S. Zhou, J. B. Goodenough, Q. Q. Liu, J. G. Zhao, L. X. Yang, Y. Yu, R. C. Yu, T. Katsura, A. Shatskiy, and E. Ito PMCID: PMC2438213 Physics Field-induced quantum critical route to a Fermi liquid in high-temperature superconductors Takasada Shibauchi, Lia Krusin-Elbaum, Masashi Hasegawa, Yuichi Kasahara, Ryuji Okazaki, and Yuji Matsuda PMCID: PMC2438214 Biological Sciences Applied Biological Sciences A gastrolith protein serving a dual role in the formation of an amorphous mineral containing extracellular matrix Assaf Shechter, Lilah Glazer, Shira Cheled, Eyal Mor, Simy Weil, Amir Berman, Shmuel Bentov, Eliahu D. Aflalo, Isam Khalaila, and Amir Sagi PMCID: PMC2438216 Cuticular hydrocarbon analysis of an awake behaving fly using direct analysis in real-time time-of-flight mass spectrometry Joanne Y. Yew, Robert B. Cody, and Edward A. Kravitz PMCID: PMC2438217 Lack of aldose 1-epimerase in Hypocrea jecorina (anamorph Trichoderma reesei): A key to cellulase gene expression on lactose Erzsébet Fekete, Bernhard Seiboth, Christian P. Kubicek, Attila Szentirmai, and Levente Karaffa PMCID: PMC2438218 Biochemistry Superoxide dismutase 1 (SOD1) is essential for H2O2-mediated oxidation and inactivation of phosphatases in growth factor signaling Jose C. Juarez, Mari Manuia, Mark E. Burnett, Oscar Betancourt, Benoit Boivin, David E. Shaw, Nicholas K. Tonks, Andrew P. Mazar, and Fernando Doñate PMCID: PMC2438219 EB1 promotes Aurora-B kinase activity through blocking its inactivation by protein phosphatase 2A Lei Sun, Jinmin Gao, Xin Dong, Min Liu, Dengwen Li, Xingjuan Shi, Jin-Tang Dong, Xianyu Lu, Chunyong Liu, and Jun Zhou PMCID: PMC2438220 Direct and selective elimination of specific prions and amyloids by 4,5-dianilinophthalimide and analogs Huan Wang, Martin L. Duennwald, Blake E. Roberts, Leslie M. Rozeboom, Yingxin L. Zhang, Andrew D. Steele, Rajaraman Krishnan, Linhui Julie Su, Drees Griffin, Samrat Mukhopadhyay, Edward J. Hennessy, Peter Weigele, Barbara J. Blanchard, Jonathan King, Ashok A. Deniz, Stephen L. Buchwald, Vernon M. Ingram, Susan Lindquist, and James Shorter PMCID: PMC2438221 Biophysics Signal processing by the HOG MAP kinase pathway Pascal Hersen, Megan N. McClean, L. Mahadevan, and Sharad Ramanathan PMCID: PMC2386076 Prediction of the tissue-specificity of selective estrogen receptor modulators by using a single biochemical method Susie Y. Dai, Michael J. Chalmers, John Bruning, Kelli S. Bramlett, Harold E. Osborne, Chahrzad Montrose-Rafizadeh, Robert J. Barr, Yong Wang, Minmin Wang, Thomas P. Burris, Jeffrey A. Dodge, and Patrick R. Griffin PMCID: PMC2438222 Prediction of membrane-protein topology from first principles Andreas Bernsel, Håkan Viklund, Jenny Falk, Erik Lindahl, Gunnar von Heijne, and Arne Elofsson PMCID: PMC2438223 Protein folding: Independent unrelated pathways or predetermined pathway with optional errors Sabrina Bédard, Mallela M. G. Krishna, Leland Mayne, and S. Walter Englander PMCID: PMC2438224 Cell Biology The α9β1 integrin enhances cell migration by polyamine-mediated modulation of an inward-rectifier potassium channel Gregory W. deHart, Taihao Jin, Diane E. McCloskey, Anthony E. Pegg, and Dean Sheppard PMCID: PMC2386075 From the Cover:
Nuclear translocation of Gln3 in response to nutrient signals requires Golgi-to-endosome trafficking in Saccharomyces cerevisiae Rekha Puria, Sara A. Zurita-Martinez, and Maria E. Cardenas PMCID: PMC2438226 Structural basis for tropomyosin overlap in thin (actin) filaments and the generation of a molecular swivel by troponin-T Kenji Murakami, Murray Stewart, Kayo Nozawa, Kumiko Tomii, Norio Kudou, Noriyuki Igarashi, Yasuo Shirakihara, Soichi Wakatsuki, Takuo Yasunaga, and Takeyuki Wakabayashi PMCID: PMC2438227 Chaperone-dependent amyloid assembly protects cells from prion toxicity Peter M. Douglas, Sebastian Treusch, Hong-Yu Ren, Randal Halfmann, Martin L. Duennwald, Susan Lindquist, and Douglas M. Cyr PMCID: PMC2438228 Developmental Biology From the Cover:
Four-dimensional analysis of vascularization during primary development of an organ, the gonad Douglas Coveney, Jonah Cool, Tim Oliver, and Blanche Capel PMCID: PMC2438229 Environmental Sciences Involvement of testicular growth factors in fetal Leydig cell aggregation after exposure to phthalate in utero Han Lin, Ren-Shan Ge, Guo-Rong Chen, Guo-Xin Hu, Lei Dong, Qing-Quan Lian, Dianne O. Hardy, Chantal M. Sottas, Xiao-Kun Li, and Matthew P. Hardy PMCID: PMC2438230 Evolution From the Cover:
Alternative splicing: A missing piece in the puzzle of intron gain Rosa Tarrío, Francisco J. Ayala, and Francisco Rodríguez-Trelles PMCID: PMC2438231 Embryology of a planktonic tunicate reveals traces of sessility Thomas Stach, Jonas Winter, Jean-Marie Bouquet, Daniel Chourrout, and Ralf Schnabel PMCID: PMC2438232 Immunology Alternative translation of osteopontin generates intracellular and secreted isoforms that mediate distinct biological activities in dendritic cells Mari L. Shinohara, Hye-Jung Kim, June-Ho Kim, Virgilio A. Garcia, and Harvey Cantor PMCID: PMC2438233 Distinct roles for IL-13 and IL-4 via IL-13 receptor α1 and the type II IL-4 receptor in asthma pathogenesis A. Munitz, E. B. Brandt, M. Mingler, F. D. Finkelman, and M. E. Rothenberg PMCID: PMC2386078 Medical Sciences Activin B receptor ALK7 is a negative regulator of pancreatic β-cell function Philippe Bertolino, Rebecka Holmberg, Eva Reissmann, Olov Andersson, Per-Olof Berggren, and Carlos F. Ibáñez PMCID: PMC2438235 Growth/differentiation factor 3 signals through ALK7 and regulates accumulation of adipose tissue and diet-induced obesity Olov Andersson, Marion Korach-Andre, Eva Reissmann, Carlos F. Ibáñez, and Philippe Bertolino PMCID: PMC2438236 Leptin responsiveness restored by amylin agonism in diet-induced obesity: Evidence from nonclinical and clinical studies Jonathan D. Roth, Barbara L. Roland, Rebecca L. Cole, James L. Trevaskis, Christian Weyer, Joy E. Koda, Christen M. Anderson, David G. Parkes, and Alain D. Baron PMCID: PMC2438237 From the Cover:
Fecal transmission of AA amyloidosis in the cheetah contributes to high incidence of disease Beiru Zhang, Yumi Une, Xiaoying Fu, Jingmin Yan, FengXia Ge, Junjie Yao, Jinko Sawashita, Masayuki Mori, Hiroshi Tomozawa, Fuyuki Kametani, and Keiichi Higuchi PMCID: PMC2377313 Common SNP in pre-miR-146a decreases mature miR expression and predisposes to papillary thyroid carcinoma Krystian Jazdzewski, Elizabeth L. Murray, Kaarle Franssila, Barbara Jarzab, Daniel R. Schoenberg, and Albert de la Chapelle PMCID: PMC2438239 Specific inhibitors of the protein tyrosine phosphatase Shp2 identified by high-throughput docking Klaus Hellmuth, Stefanie Grosskopf, Ching Tung Lum, Martin Würtele, Nadine Röder, Jens Peter von Kries, Marta Rosario, Jörg Rademann, and Walter Birchmeier PMCID: PMC2438240 cAMP/PKA pathway activation in human mesenchymal stem cells in vitro results in robust bone formation in vivo Ramakrishnaiah Siddappa, Anton Martens, Joyce Doorn, Anouk Leusink, Cristina Olivo, Ruud Licht, Linda van Rijn, Claudia Gaspar, Riccardo Fodde, Frank Janssen, Clemens van Blitterswijk, and Jan de Boer PMCID: PMC2387183 Comprehensive screening for antigens overexpressed on carcinomas via isolation of human mAbs that may be therapeutic Gene Kurosawa, Yasushi Akahori, Miwa Morita, Mariko Sumitomo, Noriko Sato, Chiho Muramatsu, Keiko Eguchi, Kazuki Matsuda, Akihiko Takasaki, Miho Tanaka, Yoshitaka Iba, Susumu Hamada-Tsutsumi, Yoshinori Ukai, Mamoru Shiraishi, Kazuhiro Suzuki, Maiko Kurosawa, Sally Fujiyama, Nobuhiro Takahashi, Ryoichi Kato, Yoshikazu Mizoguchi, Mikihiro Shamoto, Hiroyuki Tsuda, Mototaka Sugiura, Yoshinobu Hattori, Shuichi Miyakawa, Ryoichi Shiroki, Kiyotaka Hoshinaga, Nobuhiro Hayashi, Atsushi Sugioka, and Yoshikazu Kurosawa PMCID: PMC2377314 Hexadecyloxypropyl-cidofovir, CMX001, prevents adenovirus-induced mortality in a permissive, immunosuppressed animal model Karoly Toth, Jacqueline F. Spencer, Debanjan Dhar, John E. Sagartz, R. Mark L. Buller, George R. Painter, and William S. M. Wold PMCID: PMC2438243 Neuroscience Hyperpolarization-activated graded persistent activity in the prefrontal cortex Milena Winograd, Alain Destexhe, and Maria V. Sanchez-Vives PMCID: PMC2438244 From the Cover:
Reversal of opiate-induced apoptosis by human recombinant growth hormone in murine foetus primary hippocampal neuronal cell cultures Anne-Lie Svensson, Nora Bucht, Mathias Hallberg, and Fred Nyberg PMCID: PMC2438245 Cerebellar-dependent motor learning is based on pruning a Purkinje cell population response Nicolas Catz, Peter W. Dicke, and Peter Thier PMCID: PMC2438246 Electrical microstimulation thresholds for behavioral detection and saccades in monkey frontal eye fields Dona K. Murphey and John H. R. Maunsell PMCID: PMC2438247 Hypoxia and the HIF-1 transcriptional pathway reorganize a neuronal circuit for oxygen-dependent behavior in Caenorhabditis elegans Andy J. Chang and Cornelia I. Bargmann PMCID: PMC2438248 Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and Aβ accumulation Alim Muhammad, Ingrid Flores, Hong Zhang, Rui Yu, Agnieszka Staniszewski, Emmanuel Planel, Mathieu Herman, Lingling Ho, Robert Kreber, Lawrence S. Honig, Barry Ganetzky, Karen Duff, Ottavio Arancio, and Scott A. Small PMCID: PMC2386077 Estradiol modulation of phenylephrine-induced excitatory responses in ventromedial hypothalamic neurons of female rats Anna W. Lee, Andreas Kyrozis, Vivien Chevaleyre, Lee-Ming Kow, Nino Devidze, Qiuyu Zhang, Anne M. Etgen, and Donald W. Pfaff PMCID: PMC2438250 Social Sciences Social Sciences Sociality, selection, and survival: Simulated evolution of mortality with intergenerational transfers and food sharing Ronald Lee PMCID: PMC2438215 |
