| | This journal provides immediate access to some articles. Editorial The Open Access Debate Mark Hermodson PMCID: PMC2286552 Obituary Anil Lala (1950–2004) P. Balaram PMCID: PMC2286556 Accelerated Communication The C terminus of the nuclear protein NuMA: Phylogenetic distribution and structure Patricia C. Abad, I. Saira Mian, Cedric Plachot, Aniysha Nelpurackal, Carol Bator-Kelly, and Sophie A. Lelièvre PMCID: PMC2286550 Articles Characterizing specific phage–protein interactions by fluorescence correlation spectroscopy John T. Bahns, Chin-Mei Liu, and Liaohai Chen PMCID: PMC2286549 Comparison of TFII-I gene family members deleted in Williams-Beuren syndrome Timothy A. Hinsley, Pamela Cunliffe, Hannah J. Tipney, Andrew Brass, and May Tassabehji PMCID: PMC2286546 Quantification of helix–helix binding affinities in micelles and lipid bilayers Andrei L. Lomize, I.D. Pogozheva, and H.I. Mosberg PMCID: PMC2286553 Optimal bundling of transmembrane helices using sparse distance constraints Ken Sale, Jean-Loup Faulon, Genetha A. Gray, Joseph S. Schoeniger, and Malin M. Young PMCID: PMC2286557 Apo-azurin folds via an intermediate that resembles the molten-globule Anders Sandberg, Johan Leckner, and B. Göran Karlsson PMCID: PMC2286560 High-pressure refolding of bikunin: Efficacy and thermodynamics Matthew B. Seefeldt, Jun Ouyang, Wayne A. Froland, John F. Carpenter, and Theodore W. Randolph PMCID: PMC2286545 Simulating evolution by gene duplication of protein features that require multiple amino acid residues Michael J. Behe and David W. Snoke PMCID: PMC2286568 Crystallographic identification of Ca2+ and Sr2+ coordination sites in synaptotagmin I C2B domain Yuan Cheng, Sonia M. Sequeira, Lucy Malinina, Valentina Tereshko, Thomas H. Söllner, and Dinshaw J. Patel PMCID: PMC2286539 Crystal structure of Ski8p, a WD-repeat protein with dual roles in mRNA metabolism and meiotic recombination Zhihong Cheng, Yuying Liu, Chernhoe Wang, Roy Parker, and Haiwei Song PMCID: PMC2001155 Design, expression, and purification of a Flaviviridae polymerase using a high-throughput approach to facilitate crystal structure determination Kyung H. Choi, James M. Groarke, Dorothy C. Young, Michael G. Rossmann, Daniel C. Pevear, Richard J. Kuhn, and Janet L. Smith PMCID: PMC2286544 Selectivity and specificity of substrate binding in methionyl-tRNA synthetase Deepshikha Datta, Nagarajan Vaidehi, Deqiang Zhang, and William A. Goddard, III PMCID: PMC2286561 Probing the influence on folding behavior of structurally conserved core residues in P. aeruginosa apo-azurin K. Cecilia Engman, Anders Sandberg, Johan Leckner, and B. Göran Karlsson PMCID: PMC2286540 Alanine-scanning mutagenesis of the β-sheet region of phage T4 lysozyme suggests that tertiary context has a dominant effect on β-sheet formation Molly M. He, Zachary A. Wood, Walter A. Baase, Hong Xiao, and Brian W. Matthews PMCID: PMC2286564 A united residue force-field for calcium–protein interactions Mey Khalili, Jeffrey A. Saunders, Adam Liwo, Stanislaw Ołdziej, and Harold A. Scheraga PMCID: PMC2286548 Improved stability of a protein vaccine through elimination of a partially unfolded state Colleen A. McHugh, Ralph F. Tammariello, Charles B. Millard, and John H. Carra PMCID: PMC2286567 Prediction of pKa and redox properties in the thioredoxin superfamily Efrosini Moutevelis and Jim Warwicker PMCID: PMC2286559 In silico protein design by combinatorial assembly of protein building blocks Hui-Hsu (Gavin) Tsai, Chung-Jung Tsai, Buyong Ma, and Ruth Nussinov PMCID: PMC2286547 Structure and function of the Gondwanian hemoglobin of Pseudaphritis urvillii, a primitive notothenioid fish of temperate latitudes Cinzia Verde, Barry D. Howes, M. Cristina De Rosa, Luca Raiola, Giulietta Smulevich, Richard Williams, Bruno Giardina, Elio Parisi, and Guido Di Prisco PMCID: PMC2286566 High-throughput automated refolding screening of inclusion bodies Renaud Vincentelli, Stéphane Canaan, Valérie Campanacci, Christel Valencia, Damien Maurin, Frédéric Frassinetti, Loréna Scappucini-Calvo, Yves Bourne, Christian Cambillau, and Christophe Bignon PMCID: PMC2286565 Improved pKa calculations through flexibility based sampling of a water-dominated interaction scheme Jim Warwicker PMCID: PMC2286538 Protein Structure Report Crystal structure of ribosomal protein L27 from Thermus thermophilus HB8 Hongfei Wang, Chie Hori Takemoto, Kazutaka Murayama, Hiroaki Sakai, Ayako Tatsuguchi, Takaho Terada, Mikako Shirouzu, Seiki Kuramitsu, and Shigeyuki Yokoyama PMCID: PMC2286543 For the Record Sedimentation velocity studies of the high–molecular weight aggregates of the HIV gp41 ectodomain Amy Jacobs, Kari Hartman, Thomas Laue, and Michael Caffrey PMCID: PMC2286558 Circular permutation as a tool to reduce surface entropy triggers crystallization of the signal recognition particle receptor β subunit Thomas U. Schwartz, Rudolf Walczak, and Günter Blobel PMCID: PMC2286555 Signal peptide prediction based on analysis of experimentally verified cleavage sites Zemin Zhang and William J. Henzel PMCID: PMC2286551 Average protein density is a molecular-weight-dependent function Hannes Fischer, Igor Polikarpov, and Aldo F. Craievich PMCID: PMC2286542 Arm–domain interactions can provide high binding cooperativity Robert Schleif and Cynthia Wolberger PMCID: PMC2286541 The reaction of α-crystallin with the cross-linker 3,3′-dithiobis(sulfosuccinimidyl propionate) demonstrates close proximity of the C termini of αA and αB in the native assembly Catherine L. Swaim, David L. Smith, and Jean B. Smith PMCID: PMC2286569 Book Review Directed enzyme evolution: Screening and selection methods. Methods in molecular biology Vol. 230 edited by Frances H. Arnold and George Georgiou. 2003.: Totowa, NJ: Humana Press. 383 pages.
Directed evolution library creation: Methods and protocols. Methods in molecular biology, Vol. 231, edited by Frances H. Arnold and George Georgiou. 2003. Totowa, NJ: Humana Press. 224 pages.
Directed molecular evolution of proteins: Or how to improve enzymes for biocatalysis, edited by Susanne Brackmann and Kay Johnsson. 2002. Weinheim, Germany: Wiley-VCH. 357 pages. Dan S. Tawfik PMCID: PMC2286562 Correction Protein Sci. 2004 October; 13(10): 2838. PMCID: PMC2286554 Corrects: Rajamanickam Murugan, et al. A simple formalism on dynamics of proteins on potential energy landscapes. Protein Sci. 2004 February; 13(2): 487–493. |
