| | This journal provides immediate access to some articles. This Week in PNAS Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3171–3172. doi: 10.1073/iti0908105.PMCID: PMC2265159 Commentaries Modulated pairs in superconducting cuprates Michael R. Norman Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3173–3174. doi: 10.1073/pnas.0800433105.PMCID: PMC2265151 Canoes and cultural evolution Stephen Shennan Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3175–3176. doi: 10.1073/pnas.0800666105.PMCID: PMC2265163 Chance favors a prepared genome Jonathan P. Stoye and Melvyn W. Yap Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3177–3178. doi: 10.1073/pnas.0800667105.PMCID: PMC2265119 Physical Sciences Applied Mathematics Limbless undulatory propulsion on land Z. V. Guo and L. Mahadevan Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3179–3184. doi: 10.1073/pnas.0705442105.PMCID: PMC2265148 Chemistry Solvent molecules bridge the mechanical unfolding transition state of a protein Lorna Dougan, Gang Feng, Hui Lu, and Julio M. Fernandez Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3185–3190. doi: 10.1073/pnas.0706075105.PMCID: PMC2265161 Engineering Microfluidic high-throughput encapsulation and hydrodynamic self-sorting of single cells Max Chabert and Jean-Louis Viovy Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3191–3196. doi: 10.1073/pnas.0708321105.PMCID: PMC2265149 Nanometer-scale mapping and single-molecule detection with color-coded nanoparticle probes Amit Agrawal, Rajesh Deo, Geoffrey D. Wang, May D. Wang, and Shuming Nie Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3298–3303. doi: 10.1073/pnas.0712351105.PMCID: PMC2265145 Geology Pulsed oxidation and biological evolution in the Ediacaran Doushantuo Formation Kathleen A. McFadden, Jing Huang, Xuelei Chu, Ganqing Jiang, Alan J. Kaufman, Chuanming Zhou, Xunlai Yuan, and Shuhai Xiao Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3197–3202. doi: 10.1073/pnas.0708336105.PMCID: PMC2265117 Physics From the Cover: Imaging the impact on cuprate superconductivity of varying the interatomic distances within individual crystal unit cells J. A. Slezak, Jinho Lee, M. Wang, K. McElroy, K. Fujita, B. M. Andersen, P. J. Hirschfeld, H. Eisaki, S. Uchida, and J. C. Davis Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3203–3208. doi: 10.1073/pnas.0706795105.PMCID: PMC2265138 Statistics Centroid estimation in discrete high-dimensional spaces with applications in biology Luis E. Carvalho and Charles E. Lawrence Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3209–3214. doi: 10.1073/pnas.0712329105.PMCID: PMC2265131 Biological Sciences Anthropology Cosmogenic nuclide dating of Sahelanthropus tchadensis and Australopithecus bahrelghazali: Mio-Pliocene hominids from Chad Anne-Elisabeth Lebatard, Didier L. Bourlès, Philippe Duringer, Marc Jolivet, Régis Braucher, Julien Carcaillet, Mathieu Schuster, Nicolas Arnaud, Patrick Monié, Fabrice Lihoreau, Andossa Likius, Hassan Taisso Mackaye, Patrick Vignaud, and Michel Brunet Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3226–3231. doi: 10.1073/pnas.0708015105.PMCID: PMC2265126 Applied Biological Sciences Engineering of mucin-type human glycoproteins in yeast cells Koh Amano, Yasunori Chiba, Yoshiko Kasahara, Yukinari Kato, Mika Kato Kaneko, Atsushi Kuno, Hiromi Ito, Kazuo Kobayashi, Jun Hirabayashi, Yoshifumi Jigami, and Hisashi Narimatsu Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3232–3237. doi: 10.1073/pnas.0710412105.PMCID: PMC2265114 Biochemistry Two-step site selection for serine-integrase-mediated excision: DNA-directed integrase conformation and central dinucleotide proofreading Pallavi Ghosh, Lori A. Bibb, and Graham F. Hatfull Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3238–3243. doi: 10.1073/pnas.0711649105.PMCID: PMC2265153 Mitochondrial deafness alleles confer misreading of the genetic code Sven N. Hobbie, Christian M. Bruell, Subramanian Akshay, Sarath K. Kalapala, Dmitry Shcherbakov, and Erik C. Böttger Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3244–3249. doi: 10.1073/pnas.0707265105.PMCID: PMC2265171 The enzyme mechanism of nitrite reductase studied at single-molecule level Sofya Kuznetsova, Gerhild Zauner, Thijs J. Aartsma, Hans Engelkamp, Nikos Hatzakis, Alan E. Rowan, Roeland J. M. Nolte, Peter C. M. Christianen, and Gerard W. Canters Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3250–3255. doi: 10.1073/pnas.0707736105.PMCID: PMC2265120 Phenylalanine-508 mediates a cytoplasmic–membrane domain contact in the CFTR 3D structure crucial to assembly and channel function Adrian W. R. Serohijos, Tamás Hegedűs, Andrei A. Aleksandrov, Lihua He, Liying Cui, Nikolay V. Dokholyan, and John R. Riordan Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3256–3261. doi: 10.1073/pnas.0800254105.PMCID: PMC2265173 Cloning and identification of an oxytocin/vasopressin-like receptor and its ligand from insects Elisabeth Stafflinger, Karina K. Hansen, Frank Hauser, Martina Schneider, Giuseppe Cazzamali, Michael Williamson, and Cornelis J. P. Grimmelikhuijzen Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3262–3267. doi: 10.1073/pnas.0710897105.PMCID: PMC2265169 On the evolutionary significance and metal-binding characteristics of a monolobal transferrin from Ciona intestinalis Arthur D. Tinoco, Cynthia W. Peterson, Baldo Lucchese, Robert P. Doyle, and Ann M. Valentine Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3268–3273. doi: 10.1073/pnas.0705037105.PMCID: PMC2265155 PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains Chikako Suzuki, Robert G. Garces, Katherine A. Edmonds, Sebastian Hiller, Sven G. Hyberts, Assen Marintchev, and Gerhard Wagner Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3274–3279. doi: 10.1073/pnas.0712235105.PMCID: PMC2265113 Structure of glycerol-3-phosphate dehydrogenase, an essential monotopic membrane enzyme involved in respiration and metabolism Joanne I. Yeh, Unmesh Chinte, and Shoucheng Du Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3280–3285. doi: 10.1073/pnas.0712331105.PMCID: PMC2265192 Metal active site elasticity linked to activation of homocysteine in methionine synthases Markos Koutmos, Robert Pejchal, Theresa M. Bomer, Rowena G. Matthews, Janet L. Smith, and Martha L. Ludwig Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3286–3291. doi: 10.1073/pnas.0709960105.PMCID: PMC2265165 Fine structure of the promoter–σ region 1.2 interaction Shanil P. Haugen, Wilma Ross, Michele Manrique, and Richard L. Gourse Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3292–3297. doi: 10.1073/pnas.0709513105.PMCID: PMC2265156 Biophysics Limbless undulatory propulsion on land Z. V. Guo and L. Mahadevan Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3179–3184. doi: 10.1073/pnas.0705442105.PMCID: PMC2265148 Nanometer-scale mapping and single-molecule detection with color-coded nanoparticle probes Amit Agrawal, Rajesh Deo, Geoffrey D. Wang, May D. Wang, and Shuming Nie Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3298–3303. doi: 10.1073/pnas.0712351105.PMCID: PMC2265145 Relationship between cellular response and behavioral variability in bacterial chemotaxis Thierry Emonet and Philippe Cluzel Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3304–3309. doi: 10.1073/pnas.0705463105.PMCID: PMC2265172 Gating at the selectivity filter in cyclic nucleotide-gated channels Jorge E. Contreras, Deepa Srikumar, and Miguel Holmgren Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3310–3314. doi: 10.1073/pnas.0709809105.PMCID: PMC2265121 Monitoring RNA transcription in real time by using surface plasmon resonance Sandra J. Greive, Steven E. Weitzel, Jim P. Goodarzi, Lisa J. Main, Zvi Pasman, and Peter H. von Hippel Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3315–3320. doi: 10.1073/pnas.0712074105.PMCID: PMC2265150 Assessing the solvent-dependent surface area of unfolded proteins using an ensemble model Haipeng Gong and George D. Rose Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3321–3326. doi: 10.1073/pnas.0712240105.PMCID: PMC2265189 Cell Biology Microfluidic high-throughput encapsulation and hydrodynamic self-sorting of single cells Max Chabert and Jean-Louis Viovy Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3191–3196. doi: 10.1073/pnas.0708321105.PMCID: PMC2265149 Yeast Pch2 promotes domainal axis organization, timely recombination progression, and arrest of defective recombinosomes during meiosis G. Valentin Börner, Aekam Barot, and Nancy Kleckner Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3327–3332. doi: 10.1073/pnas.0711864105.PMCID: PMC2265181 A GATA-1-regulated microRNA locus essential for erythropoiesis Louis C. Dore, Julio D. Amigo, Camila O. dos Santos, Zhe Zhang, Xiaowu Gai, John W. Tobias, Duonan Yu, Alyssa M. Klein, Christine Dorman, Weisheng Wu, Ross C. Hardison, Barry H. Paw, and Mitchell J. Weiss Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3333–3338. doi: 10.1073/pnas.0712312105.PMCID: PMC2265118 Glucocorticoids differentially regulate degradation of MyoD and Id1 by N-terminal ubiquitination to promote muscle protein catabolism Liping Sun, Julie S. Trausch-Azar, Louis J. Muglia, and Alan L. Schwartz Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3339–3344. doi: 10.1073/pnas.0800165105.PMCID: PMC2265166 Shear stress regulates aquaporin-5 and airway epithelial barrier function Venkataramana K. Sidhaye, Kelly S. Schweitzer, Michael J. Caterina, Larissa Shimoda, and Landon S. King Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3345–3350. doi: 10.1073/pnas.0712287105.PMCID: PMC2265191 A trans-Golgi network golgin is required for the regulated secretion of TNF in activated macrophages in vivo Zi Zhao Lieu, John G. Lock, Luke A. Hammond, Nicole L. La Gruta, Jennifer L. Stow, and Paul A. Gleeson Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3351–3356. doi: 10.1073/pnas.0800137105.PMCID: PMC2265200 Association of guanine nucleotide-exchange protein BIG1 in HepG2 cell nuclei with nucleolin, U3 snoRNA, and fibrillarin Philip Ian Padilla, Marina Uhart, Gustavo Pacheco-Rodriguez, Brenda A. Peculis, Joel Moss, and Martha Vaughan Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3357–3361. doi: 10.1073/pnas.0712387105.PMCID: PMC2265132 Myocardin inhibits cellular proliferation by inhibiting NF-κB(p65)-dependent cell cycle progression Ru-hang Tang, Xi-Long Zheng, Thomas E. Callis, William E. Stansfield, Jiayin He, Albert S. Baldwin, Da-Zhi Wang, and Craig H. Selzman Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3362–3367. doi: 10.1073/pnas.0705842105.PMCID: PMC2265140 Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways Xiaofeng Zheng, Sarah Linke, José M. Dias, Xiaowei Zheng, Katarina Gradin, Tristan P. Wallis, Brett R. Hamilton, Maria Gustafsson, Jorge L. Ruas, Sarah Wilkins, Rebecca L. Bilton, Kerstin Brismar, Murray L. Whitelaw, Teresa Pereira, Jeffrey J. Gorman, Johan Ericson, Daniel J. Peet, Urban Lendahl, and Lorenz Poellinger Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3368–3373. doi: 10.1073/pnas.0711591105.PMCID: PMC2265116 A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy In Hye Lee, Liu Cao, Raul Mostoslavsky, David B. Lombard, Jie Liu, Nicholas E. Bruns, Maria Tsokos, Frederick W. Alt, and Toren Finkel Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3374–3379. doi: 10.1073/pnas.0712145105.PMCID: PMC2265142 Loss of Bardet–Biedl syndrome proteins alters the morphology and function of motile cilia in airway epithelia Alok S. Shah, Sara L. Farmen, Thomas O. Moninger, Thomas R. Businga, Michael P. Andrews, Kevin Bugge, Charles C. Searby, Darryl Nishimura, Kim A. Brogden, Joel N. Kline, Val C. Sheffield, and Michael J. Welsh Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3380–3385. doi: 10.1073/pnas.0712327105.PMCID: PMC2265193 Splicing promotes rapid and efficient mRNA export in mammalian cells Patricia Valencia, Anusha P. Dias, and Robin Reed Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3386–3391. doi: 10.1073/pnas.0800250105.PMCID: PMC2265164 Developmental Biology Highly efficient and large-scale generation of functional dopamine neurons from human embryonic stem cells Myung Soo Cho, Young-Eun Lee, Ji Young Kim, Seungsoo Chung, Yoon Hee Cho, Dae-Sung Kim, Sang-Moon Kang, Haksup Lee, Myung-Hwa Kim, Jeong-Hoon Kim, Joong Woo Leem, Sun Kyung Oh, Young Min Choi, Dong-Youn Hwang, Jin Woo Chang, and Dong-Wook Kim Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3392–3397. doi: 10.1073/pnas.0712359105.PMCID: PMC2265201 Border formation in a Bmp gradient reduced to single dissociated cells Jia Sheng Hu, Linda T. Doan, D. Spencer Currle, Michelle Paff, Justin Y. Rheem, Rachel Schreyer, Benoit Robert, and Edwin S. Monuki Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3398–3403. doi: 10.1073/pnas.0709100105.PMCID: PMC2265170 Ecology From the Cover: Behavioral consequences of innate preferences and olfactory learning in hawkmoth–flower interactions Jeffrey A. Riffell, Ruben Alarcón, Leif Abrell, Goggy Davidowitz, Judith L. Bronstein, and John G. Hildebrand Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3404–3409. doi: 10.1073/pnas.0709811105.PMCID: PMC2265144 Impact of an extreme climatic event on community assembly Katherine M. Thibault and James H. Brown Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3410–3415. doi: 10.1073/pnas.0712282105.PMCID: PMC2265133 Evolution Distinct genomic signatures of adaptation in pre- and postnatal environments during human evolution Monica Uddin, Morris Goodman, Offer Erez, Roberto Romero, Guozhen Liu, Munirul Islam, Juan C. Opazo, Chet C. Sherwood, Lawrence I. Grossman, and Derek E. Wildman Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3215–3220. doi: 10.1073/pnas.0712400105.PMCID: PMC2265188 From the Cover: Natural selection and cultural rates of change Deborah S. Rogers and Paul R. Ehrlich Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3416–3420. doi: 10.1073/pnas.0711802105.PMCID: PMC2265130 A genome-wide signature of positive selection in ancient and recent invasive expansions of the honey bee Apis mellifera Amro Zayed and Charles W. Whitfield Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3421–3426. doi: 10.1073/pnas.0800107105.PMCID: PMC2265178 Whole-genome analysis reveals molecular innovations and evolutionary transitions in chromalveolate species Cindy Martens, Klaas Vandepoele, and Yves Van de Peer Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3427–3432. doi: 10.1073/pnas.0712248105.PMCID: PMC2265158 Replication timing, chromosomal bands, and isochores Maria Costantini and Giorgio Bernardi Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3433–3437. doi: 10.1073/pnas.0710587105.PMCID: PMC2265141 Genetics Centroid estimation in discrete high-dimensional spaces with applications in biology Luis E. Carvalho and Charles E. Lawrence Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3209–3214. doi: 10.1073/pnas.0712329105.PMCID: PMC2265131 Functionally significant insulin-like growth factor I receptor mutations in centenarians Yousin Suh, Gil Atzmon, Mi-Ook Cho, David Hwang, Bingrong Liu, Daniel J. Leahy, Nir Barzilai, and Pinchas Cohen Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3438–3442. doi: 10.1073/pnas.0705467105.PMCID: PMC2265137 Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers Thomas D. Barber, Kirk McManus, Karen W. Y. Yuen, Marcelo Reis, Giovanni Parmigiani, Dong Shen, Irene Barrett, Yasaman Nouhi, Forrest Spencer, Sanford Markowitz, Victor E. Velculescu, Kenneth W. Kinzler, Bert Vogelstein, Christoph Lengauer, and Philip Hieter Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3443–3448. doi: 10.1073/pnas.0712384105.PMCID: PMC2265152 Genetic interaction between members of the Vangl family causes neural tube defects in mice Elena Torban, Anne-Marie Patenaude, Severine Leclerc, Staci Rakowiecki, Susan Gauthier, Gregor Andelfinger, Douglas J. Epstein, and Philippe Gros Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3449–3454. doi: 10.1073/pnas.0712126105.PMCID: PMC2265143 A translocation causing increased α-Klotho level results in hypophosphatemic rickets and hyperparathyroidism Catherine A. Brownstein, Felix Adler, Carol Nelson-Williams, Junko Iijima, Peining Li, Akihiro Imura, Yo-ichi Nabeshima, Miguel Reyes-Mugica, Thomas O. Carpenter, and Richard P. Lifton Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3455–3460. doi: 10.1073/pnas.0712361105.PMCID: PMC2265125 Defining genetic interaction Ramamurthy Mani, Robert P. St.Onge, John L. Hartman, IV, Guri Giaever, and Frederick P. Roth Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3461–3466. doi: 10.1073/pnas.0712255105.PMCID: PMC2265146 DNA instability in postmitotic neurons Roman Gonitel, Hilary Moffitt, Kirupa Sathasivam, Ben Woodman, Peter J. Detloff, Richard L. M. Faull, and Gillian P. Bates Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3467–3472. doi: 10.1073/pnas.0800048105.PMCID: PMC2265187 Whole-genome comparison of disease and carriage strains provides insights into virulence evolution in Neisseria meningitidis Christoph Schoen, Jochen Blom, Heike Claus, Anja Schramm-Glück, Petra Brandt, Tobias Müller, Alexander Goesmann, Biju Joseph, Sebastian Konietzny, Oliver Kurzai, Corinna Schmitt, Torben Friedrich, Burkhard Linke, Ulrich Vogel, and Matthias Frosch Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3473–3478. doi: 10.1073/pnas.0800151105.PMCID: PMC2265139 Immunology Induction of antigen-specific regulatory T cells in wild-type mice: Visualization and targets of suppression Panayotis Verginis, Katherine A. McLaughlin, Kai W. Wucherpfennig, Harald von Boehmer, and Irina Apostolou Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3479–3484. doi: 10.1073/pnas.0800149105.PMCID: PMC2265184 Broad dispersion and lung localization of virus-specific memory B cells induced by influenza pneumonia Hye Mee Joo, Yuxia He, and Mark Y. Sangster Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3485–3490. doi: 10.1073/pnas.0800003105.PMCID: PMC2265167 MHC class II stabilization at the surface of human dendritic cells is the result of maturation-dependent MARCH I down-regulation Aude De Gassart, Voahirana Camosseto, Jacques Thibodeau, Maurizio Ceppi, Nadia Catalan, Philippe Pierre, and Evelina Gatti Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3491–3496. doi: 10.1073/pnas.0708874105.PMCID: PMC2265198 Notch regulates IL-10 production by T helper 1 cells Sascha Rutz, Marko Janke, Nadine Kassner, Thordis Hohnstein, Manuela Krueger, and Alexander Scheffold Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3497–3502. doi: 10.1073/pnas.0712102105.PMCID: PMC2265185 Control of canonical NF-κB activation through the NIK–IKK complex pathway Brian Zarnegar, Soh Yamazaki, Jeannie Q. He, and Genhong Cheng Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3503–3508. doi: 10.1073/pnas.0707959105.PMCID: PMC2265190 SPAS-1 (stimulator of prostatic adenocarcinoma-specific T cells)/SH3GLB2: A prostate tumor antigen identified by CTLA-4 blockade Marcella Fassò, Rebecca Waitz, Yafei Hou, Tae Rim, Norman M. Greenberg, Nilabh Shastri, Lawrence Fong, and James P. Allison Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3509–3514. doi: 10.1073/pnas.0712269105.PMCID: PMC2265147 Interleukin-32 induces the differentiation of monocytes into macrophage-like cells Mihai G. Netea, Eli C. Lewis, Tania Azam, Leo A. B. Joosten, Jun Jaekal, Su-Young Bae, Charles A. Dinarello, and Soo-Hyun Kim Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3515–3520. doi: 10.1073/pnas.0712381105.PMCID: PMC2265135 Medical Sciences Transcriptome sequencing of malignant pleural mesothelioma tumors David J. Sugarbaker, William G. Richards, Gavin J. Gordon, Lingsheng Dong, Assunta De Rienzo, Gautam Maulik, Jonathan N. Glickman, Lucian R. Chirieac, Mor-Li Hartman, Bruce E. Taillon, Lei Du, Pascal Bouffard, Stephen F. Kingsmore, Neil A. Miller, Andrew D. Farmer, Roderick V. Jensen, Steven R. Gullans, and Raphael Bueno Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3521–3526. doi: 10.1073/pnas.0712399105.PMCID: PMC2265129 Both ovarian hormones estrogen and progesterone are necessary for hormonal mammary carcinogenesis in ovariectomized ACI rats Edward W. Blank, Po-Yin Wong, Rajkumar Lakshmanaswamy, Raphael Guzman, and Satyabrata Nandi Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3527–3532. doi: 10.1073/pnas.0710535105.PMCID: PMC2265202 PD-1 deficiency reveals various tissue-specific autoimmunity by H-2b and dose-dependent requirement of H-2g7 for diabetes in NOD mice Taku Yoshida, Fang Jiang, Tasuku Honjo, and Taku Okazaki Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3533–3538. doi: 10.1073/pnas.0710951105.PMCID: PMC2265199 Mesenchymal–epithelial interactions involving epiregulin in tuberous sclerosis complex hamartomas Shaowei Li, Fumiko Takeuchi, Ji-an Wang, Qingyuan Fan, Toshi Komurasaki, Eric M. Billings, Gustavo Pacheco-Rodriguez, Joel Moss, and Thomas N. Darling Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3539–3544. doi: 10.1073/pnas.0712397105.PMCID: PMC2265180 Overexpression of the dual-specificity phosphatase MKP-4/DUSP-9 protects against stress-induced insulin resistance Brice Emanuelli, Delphine Eberlé, Ryo Suzuki, and C. Ronald Kahn Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3545–3550. doi: 10.1073/pnas.0712275105.PMCID: PMC2265194 Intestinal alkaline phosphatase is a gut mucosal defense factor maintained by enteral nutrition Ross F. Goldberg, William G. Austen, Jr., Xiaobo Zhang, Gitonga Munene, Golam Mostafa, Shaluk Biswas, Michael McCormack, Kyle R. Eberlin, John T. Nguyen, Hamit S. Tatlidede, H. Shaw Warren, Sonoko Narisawa, Jose L. Millán, and Richard A. Hodin Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3551–3556. doi: 10.1073/pnas.0712140105.PMCID: PMC2265168 Microbiology From the Cover: Independent evolution of an antiviral TRIMCyp in rhesus macaques Sam J. Wilson, Benjamin L. J. Webb, Laura M. J. Ylinen, Ernst Verschoor, Jonathan L. Heeney, and Greg J. Towers Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3557–3562. doi: 10.1073/pnas.0709003105.PMCID: PMC2265179 From the Cover: Independent genesis of chimeric TRIM5-cyclophilin proteins in two primate species Cesar A. Virgen, Zerina Kratovac, Paul D. Bieniasz, and Theodora Hatziioannou Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3563–3568. doi: 10.1073/pnas.0709258105.PMCID: PMC2265128 From the Cover: TRIMCyp expression in Old World primates Macaca nemestrina and Macaca fascicularis Greg Brennan, Yury Kozyrev, and Shiu-Lok Hu Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3569–3574. doi: 10.1073/pnas.0709511105.PMCID: PMC2265124 Protection from fatal viral encephalomyelitis: AMPA receptor antagonists have a direct effect on the inflammatory response to infection Ivorlyne P. Greene, Eun-Young Lee, Natalie Prow, Brownhilda Ngwang, and Diane E. Griffin Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3575–3580. doi: 10.1073/pnas.0712390105.PMCID: PMC2265123 Neuroscience From the Cover: Categorical perception of color is lateralized to the right hemisphere in infants, but to the left hemisphere in adults A. Franklin, G. V. Drivonikou, L. Bevis, I. R. L. Davies, P. Kay, and T. Regier Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3221–3225. doi: 10.1073/pnas.0712286105.PMCID: PMC2265127 Origin and progeny of reactive gliosis: A source of multipotent cells in the injured brain Annalisa Buffo, Inmaculada Rite, Pratibha Tripathi, Alexandra Lepier, Dilek Colak, Ana-Paula Horn, Tetsuji Mori, and Magdalena Götz Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3581–3586. doi: 10.1073/pnas.0709002105.PMCID: PMC2265175 Altered morphology and 3D architecture of brain vasculature in a mouse model for Alzheimer's disease Eric P. Meyer, Alexandra Ulmann-Schuler, Matthias Staufenbiel, and Thomas Krucker Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3587–3592. doi: 10.1073/pnas.0709788105.PMCID: PMC2265182 Large-scale model of mammalian thalamocortical systems Eugene M. Izhikevich and Gerald M. Edelman Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3593–3598. doi: 10.1073/pnas.0712231105.PMCID: PMC2265160 Human single-neuron responses at the threshold of conscious recognition R. Quian Quiroga, R. Mukamel, E. A. Isham, R. Malach, and I. Fried Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3599–3604. doi: 10.1073/pnas.0707043105.PMCID: PMC2265174 fMRI mapping of a morphed continuum of 3D shapes within inferior temporal cortex Roger B. H. Tootell, Kathryn J. Devaney, Jeremy C. Young, Gheorghe Postelnicu, Reza Rajimehr, and Leslie G. Ungerleider Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3605–3609. doi: 10.1073/pnas.0712274105.PMCID: PMC2265115 Peptidergic influences on proliferation, migration, and placement of neural progenitors in the adult mouse forebrain Davor Stanić, Gustavo Paratcha, Fernanda Ledda, Herbert Herzog, Alan S. Kopin, and Tomas Hökfelt Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3610–3615. doi: 10.1073/pnas.0712303105.PMCID: PMC2265196 Regulation of synaptic inhibition by phospho-dependent binding of the AP2 complex to a YECL motif in the GABAA receptor γ2 subunit Josef T. Kittler, Guojun Chen, Viktoria Kukhtina, Ardeschir Vahedi-Faridi, Zhenglin Gu, Verena Tretter, Katharine R. Smith, Kristina McAinsh, I. Lorena Arancibia-Carcamo, Wolfram Saenger, Volker Haucke, Zhen Yan, and Stephen J. Moss Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3616–3621. doi: 10.1073/pnas.0707920105.PMCID: PMC2265186 Akt and CHIP coregulate tau degradation through coordinated interactions Chad A. Dickey, John Koren, Yong-Jie Zhang, Ya-fei Xu, Umesh K. Jinwal, Morris J. Birnbaum, Bobby Monks, Mei Sun, Jin Q. Cheng, Cam Patterson, Rachel M. Bailey, Judith Dunmore, Sareh Soresh, Carlos Leon, Dave Morgan, and Leonard Petrucelli Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3622–3627. doi: 10.1073/pnas.0709180105.PMCID: PMC2265134 Pharmacology Pharmacological disruption of calcium channel trafficking by the α2δ ligand gabapentin Jan Hendrich, Alexandra Tran Van Minh, Fay Heblich, Manuela Nieto-Rostro, Katrin Watschinger, Jörg Striessnig, Jack Wratten, Anthony Davies, and Annette C. Dolphin Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3628–3633. doi: 10.1073/pnas.0708930105.PMCID: PMC2265195 Physiology Proteomic analysis of lithium-induced nephrogenic diabetes insipidus: Mechanisms for aquaporin 2 down-regulation and cellular proliferation Jakob Nielsen, Jason D. Hoffert, Mark A. Knepper, Peter Agre, Søren Nielsen, and Robert A. Fenton Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3634–3639. doi: 10.1073/pnas.0800001105.PMCID: PMC2265122 Plant Biology Microarray analyses reveal that plant mutagenesis may induce more transcriptomic changes than transgene insertion Rita Batista, Nelson Saibo, Tiago Lourenço, and Maria Margarida Oliveira Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3640–3645. doi: 10.1073/pnas.0707881105.PMCID: PMC2265136 Distinct regulatory role for RFL, the rice LFY homolog, in determining flowering time and plant architecture Nagashree N. Rao, Kalika Prasad, Puja Ravi Kumar, and Usha Vijayraghavan Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3646–3651. doi: 10.1073/pnas.0709059105.PMCID: PMC2265177 Psychology Prefrontal and amygdala volumes are related to adolescents' affective behaviors during parent–adolescent interactions Sarah Whittle, Marie B. H. Yap, Murat Yücel, Alex Fornito, Julian G. Simmons, Anna Barrett, Lisa Sheeber, and Nicholas B. Allen Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3652–3657. doi: 10.1073/pnas.0709815105.PMCID: PMC2265176 Social Sciences Anthropology Distinct genomic signatures of adaptation in pre- and postnatal environments during human evolution Monica Uddin, Morris Goodman, Offer Erez, Roberto Romero, Guozhen Liu, Munirul Islam, Juan C. Opazo, Chet C. Sherwood, Lawrence I. Grossman, and Derek E. Wildman Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3215–3220. doi: 10.1073/pnas.0712400105.PMCID: PMC2265188 Psychology From the Cover: Categorical perception of color is lateralized to the right hemisphere in infants, but to the left hemisphere in adults A. Franklin, G. V. Drivonikou, L. Bevis, I. R. L. Davies, P. Kay, and T. Regier Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3221–3225. doi: 10.1073/pnas.0712286105.PMCID: PMC2265127 Prefrontal and amygdala volumes are related to adolescents' affective behaviors during parent–adolescent interactions Sarah Whittle, Marie B. H. Yap, Murat Yücel, Alex Fornito, Julian G. Simmons, Anna Barrett, Lisa Sheeber, and Nicholas B. Allen Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3652–3657. doi: 10.1073/pnas.0709815105.PMCID: PMC2265176 Corrections Correction for Olson, Gravitational dynamos and the low-frequency geomagnetic secular variation Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3658. doi: 10.1073/pnas.0800480105.PMCID: PMC2265197 Corrects: P. Olson. Gravitational dynamos and the low-frequency geomagnetic secular variation. Proc Natl Acad Sci U S A. 2007 December 18; 104(51): 20159–20166. Correction for Cotrell et al., Instability in pipe flow Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3658. doi: 10.1073/pnas.0801024105.PMCID: PMC2265162 Corrects: D. L. Cotrell, et al. Instability in pipe flow. Proc Natl Acad Sci U S A. 2008 January 15; 105(2): 428–430. Correction for Li et al., The globular tail domain puts on the brake to stop the ATPase cycle of myosin Va Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3658. doi: 10.1073/pnas.0801004105.PMCID: PMC2265183 Corrects: Xiang-dong Li, et al. The globular tail domain puts on the brake to stop the ATPase cycle of myosin Va. Proc Natl Acad Sci U S A. 2008 January 29; 105(4): 1140–1145. Correction for Zhao et al., Linking pattern formation to cell-type specification: Dichaete and Ind directly repress achaete gene expression in the Drosophila CNS Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3658. doi: 10.1073/pnas.0800385105.PMCID: PMC2265154 Corrects: Guoyan Zhao, et al. Linking pattern formation to cell-type specification: Dichaete and Ind directly repress achaete gene expression in the Drosophila CNS. Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3847–3852. Retraction Retraction for Holweg and Nick, Arabidopsis myosin XI mutant is defective in organelle movement and polar auxin transport Carola Holweg and Peter Nick Proc Natl Acad Sci U S A. 2008 March 4; 105(9): 3658. doi: 10.1073/pnas.0801065105.PMCID: PMC2265157 Retracts: Carola Holweg, et al. Arabidopsis myosin XI mutant is defective in organelle movement and polar auxin transport. Proc Natl Acad Sci U S A. 2004 July 13; 101(28): 10488–10493. |