| | This journal provides immediate access to some articles. Opinions Novel Insights into Disseminated Candidiasis: Pathogenesis Research and Clinical Experience Converge Brad Spellberg PLoS Pathog. 2008 February; 4(2): e38. Published online 2008 February 15. doi: 10.1371/journal.ppat.0040038.PMCID: PMC2242839 Review Parallels between Pathogens and Gluten Peptides in Celiac Sprue Michael T Bethune and Chaitan Khosla PLoS Pathog. 2008 February; 4(2): e34. Published online 2008 February 29. doi: 10.1371/journal.ppat.0040034.PMCID: PMC2323203 Research Articles Interaction of Polymerase Subunit PB2 and NP with Importin α1 Is a Determinant of Host Range of Influenza A Virus Gülsah Gabriel, Astrid Herwig, and Hans-Dieter Klenk PLoS Pathog. 2008 February; 4(2): e11. Published online 2008 February 1. doi: 10.1371/journal.ppat.0040011.PMCID: PMC2222953 TRIM E3 Ligases Interfere with Early and Late Stages of the Retroviral Life Cycle Pradeep D Uchil, Brian D Quinlan, Wai-Tsing Chan, Joseph M Luna, and Walther Mothes PLoS Pathog. 2008 February; 4(2): e16. Published online 2008 February 1. doi: 10.1371/journal.ppat.0040016.PMCID: PMC2222954 The Mannose Receptor Mediates Dengue Virus Infection of Macrophages Joanna L Miller, Barend J. M deWet, Luisa Martinez-Pomares, Catherine M Radcliffe, Raymond A Dwek, Pauline M Rudd, and Siamon Gordon PLoS Pathog. 2008 February; 4(2): e17. Published online 2008 February 8. doi: 10.1371/journal.ppat.0040017.PMCID: PMC2233670 The Effect of Trim5 Polymorphisms on the Clinical Course of HIV-1 Infection Daniëlle van Manen, Maarten A. N Rits, Corrine Beugeling, Karel van Dort, Hanneke Schuitemaker, and Neeltje A Kootstra PLoS Pathog. 2008 February; 4(2): e18. Published online 2008 February 1. doi: 10.1371/journal.ppat.0040018.PMCID: PMC2222955 Plasmodium falciparum Regulatory Subunit of cAMP-Dependent PKA and Anion Channel Conductance Anaïs Merckx, Marie-Paule Nivez, Guillaume Bouyer, Pietro Alano, Gordon Langsley, Kirk Deitsch, Serge Thomas, Christian Doerig, and Stéphane Egée PLoS Pathog. 2008 February; 4(2): e19. Published online 2008 February 1. doi: 10.1371/journal.ppat.0040019.PMCID: PMC2222956 The Macaque Gut Microbiome in Health, Lentiviral Infection, and Chronic Enterocolitis Philip McKenna, Christian Hoffmann, Nana Minkah, Pyone Pyone Aye, Andrew Lackner, Zongzhi Liu, Catherine A Lozupone, Micah Hamady, Rob Knight, and Frederic D Bushman PLoS Pathog. 2008 February; 4(2): e20. Published online 2008 February 1. doi: 10.1371/journal.ppat.0040020.PMCID: PMC2222957 Brucella Control of Dendritic Cell Maturation Is Dependent on the TIR-Containing Protein Btp1 Suzana P Salcedo, María Ines Marchesini, Hugues Lelouard, Emilie Fugier, Gilles Jolly, Stephanie Balor, Alexandre Muller, Nicolas Lapaque, Olivier Demaria, Lena Alexopoulou, Diego J Comerci, Rodolfo A Ugalde, Philippe Pierre, and Jean-Pierre Gorvel PLoS Pathog. 2008 February; 4(2): e21. Published online 2008 February 8. doi: 10.1371/journal.ppat.0040021.PMCID: PMC2233671 Inhibition of IκB Kinase by Vaccinia Virus Virulence Factor B14 Ron A.-J Chen, Grigory Ryzhakov, Samantha Cooray, Felix Randow, and Geoffrey L Smith PLoS Pathog. 2008 February; 4(2): e22. Published online 2008 February 8. doi: 10.1371/journal.ppat.0040022.PMCID: PMC2233672 Persistent Coxiella burnetii Infection in Mice Overexpressing IL-10: An Efficient Model for Chronic Q Fever Pathogenesis Soraya Meghari, Yassina Bechah, Christian Capo, Hubert Lepidi, Didier Raoult, Peter J Murray, and Jean-Louis Mege PLoS Pathog. 2008 February; 4(2): e23. Published online 2008 February 1. doi: 10.1371/journal.ppat.0040023.PMCID: PMC2222951 A Francisella Mutant in Lipid A Carbohydrate Modification Elicits Protective Immunity Duangjit Kanistanon, Adeline M Hajjar, Mark R Pelletier, Larry A Gallagher, Thomas Kalhorn, Scott A Shaffer, David R Goodlett, Laurence Rohmer, Mitchell J Brittnacher, Shawn J Skerrett, and Robert K Ernst PLoS Pathog. 2008 February; 4(2): e24. Published online 2008 February 8. doi: 10.1371/journal.ppat.0040024.PMCID: PMC2233673 Structural and Biochemical Bases for the Inhibition of Autophagy and Apoptosis by Viral BCL-2 of Murine γ-Herpesvirus 68 Bonsu Ku, Jae-Sung Woo, Chengyu Liang, Kwang-Hoon Lee, Hyang-Suk Hong, Xiaofei E, Key-Sun Kim, Jae U Jung, and Byung-Ha Oh PLoS Pathog. 2008 February; 4(2): e25. Published online 2008 February 1. doi: 10.1371/journal.ppat.0040025.PMCID: PMC2222952 NetB, a New Toxin That Is Associated with Avian Necrotic Enteritis Caused by Clostridium perfringens Anthony L Keyburn, John D Boyce, Paola Vaz, Trudi L Bannam, Mark E Ford, Dane Parker, Antonio Di Rubbo, Julian I Rood, and Robert J Moore PLoS Pathog. 2008 February; 4(2): e26. Published online 2008 February 8. doi: 10.1371/journal.ppat.0040026.PMCID: PMC2233674 Tonsilar NK Cells Restrict B Cell Transformation by the Epstein-Barr Virus via IFN-γ Till Strowig, Fabienne Brilot, Frida Arrey, Gwenola Bougras, Dolca Thomas, William A Muller, and Christian Münz PLoS Pathog. 2008 February; 4(2): e27. Published online 2008 February 8. doi: 10.1371/journal.ppat.0040027.PMCID: PMC2233668 Methamphetamine Inhibits Antigen Processing, Presentation, and Phagocytosis Zsolt Tallóczy, Jose Martinez, Danielle Joset, Yonaton Ray, Attila Gácser, Sima Toussi, Noboru Mizushima, Josh Nosanchuk, Harris Goldstein, John Loike, David Sulzer, and Laura Santambrogio PLoS Pathog. 2008 February; 4(2): e28. Published online 2008 February 15. doi: 10.1371/journal.ppat.0040028.PMCID: PMC2242831 A Mouse Model for Chikungunya: Young Age and Inefficient Type-I Interferon Signaling Are Risk Factors for Severe Disease Thérèse Couderc, Fabrice Chrétien, Clémentine Schilte, Olivier Disson, Madly Brigitte, Florence Guivel-Benhassine, Yasmina Touret, Georges Barau, Nadège Cayet, Isabelle Schuffenecker, Philippe Desprès, Fernando Arenzana-Seisdedos, Alain Michault, Matthew L Albert, and Marc Lecuit PLoS Pathog. 2008 February; 4(2): e29. Published online 2008 February 15. doi: 10.1371/journal.ppat.0040029.PMCID: PMC2242832 A Role for NKG2D in NK Cell–Mediated Resistance to Poxvirus Disease Min Fang, Lewis L Lanier, and Luis J Sigal PLoS Pathog. 2008 February; 4(2): e30. Published online 2008 February 8. doi: 10.1371/journal.ppat.0040030.PMCID: PMC2233669 Salp15 Binding to DC-SIGN Inhibits Cytokine Expression by Impairing both Nucleosome Remodeling and mRNA Stabilization Joppe W. R Hovius, Marein A. W. P de Jong, Jeroen den Dunnen, Manja Litjens, Erol Fikrig, Tom van der Poll, Sonja I Gringhuis, and Teunis B. H Geijtenbeek PLoS Pathog. 2008 February; 4(2): e31. Published online 2008 February 15. doi: 10.1371/journal.ppat.0040031.PMCID: PMC2242833 The Landscape of Human Proteins Interacting with Viruses and Other Pathogens Matthew D Dyer, T. M Murali, and Bruno W Sobral PLoS Pathog. 2008 February; 4(2): e32. Published online 2008 February 15. doi: 10.1371/journal.ppat.0040032.PMCID: PMC2242834 Control of M. tuberculosis ESAT-6 Secretion and Specific T Cell Recognition by PhoP Wafa Frigui, Daria Bottai, Laleh Majlessi, Marc Monot, Emmanuelle Josselin, Priscille Brodin, Thierry Garnier, Brigitte Gicquel, Carlos Martin, Claude Leclerc, Stewart T Cole, and Roland Brosch PLoS Pathog. 2008 February; 4(2): e33. Published online 2008 February 15. doi: 10.1371/journal.ppat.0040033.PMCID: PMC2242835 Mucosal Damage and Neutropenia Are Required for Candida albicans Dissemination Andrew Y Koh, Julia R Köhler, Kathleen T Coggshall, Nico Van Rooijen, and Gerald B Pier PLoS Pathog. 2008 February; 4(2): e35. Published online 2008 February 15. doi: 10.1371/journal.ppat.0040035.PMCID: PMC2242836 Forward Genetic Analysis of the Apicomplexan Cell Division Cycle in Toxoplasma gondii Marc-Jan Gubbels, Margaret Lehmann, Mani Muthalagi, Maria E Jerome, Carrie F Brooks, Tomasz Szatanek, Jayme Flynn, Ben Parrot, Josh Radke, Boris Striepen, and Michael W White PLoS Pathog. 2008 February; 4(2): e36. Published online 2008 February 15. doi: 10.1371/journal.ppat.0040036.PMCID: PMC2242837 Nucleotide Biosynthesis Is Critical for Growth of Bacteria in Human Blood Shalaka Samant, Hyunwoo Lee, Mahmood Ghassemi, Juan Chen, James L Cook, Alexander S Mankin, and Alexander A Neyfakh PLoS Pathog. 2008 February; 4(2): e37. Published online 2008 February 15. doi: 10.1371/journal.ppat.0040037.PMCID: PMC2242838 Human Innate Mycobacterium tuberculosis–Reactive αβTCR+ Thymocytes Marielle C Gold, Heather D Ehlinger, Matthew S Cook, Susan K Smyk-Pearson, Paul T Wille, Ross M Ungerleider, Deborah A Lewinsohn, and David M Lewinsohn PLoS Pathog. 2008 February; 4(2): e39. Published online 2008 February 15. doi: 10.1371/journal.ppat.0040039.PMCID: PMC2242840 Nanobacteria Are Mineralo Fetuin Complexes Didier Raoult, Michel Drancourt, Saïd Azza, Claude Nappez, Régis Guieu, Jean-Marc Rolain, Patrick Fourquet, Bernard Campagna, Bernard La Scola, Jean-Louis Mege, Pascal Mansuelle, Eric Lechevalier, Yvon Berland, Jean-Pierre Gorvel, and Patricia Renesto PLoS Pathog. 2008 February; 4(2): e41. Published online 2008 February 15. doi: 10.1371/journal.ppat.0040041.PMCID: PMC2242841 Structural Insight into Epitopes in the Pregnancy-Associated Malaria Protein VAR2CSA Pernille Andersen, Morten A Nielsen, Mafalda Resende, Thomas S Rask, Madeleine Dahlbäck, Thor Theander, Ole Lund, and Ali Salanti PLoS Pathog. 2008 February; 4(2): e42. Published online 2008 February 15. doi: 10.1371/journal.ppat.0040042.PMCID: PMC2242842 Structure–Function Aspects of PstS in Multi-Drug–Resistant Pseudomonas aeruginosa Olga Zaborina, Christopher Holbrook, Yimei Chen, Jason Long, Alexander Zaborin, Irina Morozova, Hoylan Fernandez, Yingmin Wang, Jerrold R Turner, and John C Alverdy PLoS Pathog. 2008 February; 4(2): e43. Published online 2008 February 15. doi: 10.1371/journal.ppat.0040043.PMCID: PMC2242829 Iron Source Preference and Regulation of Iron Uptake in Cryptococcus neoformans Won Hee Jung, Anita Sham, Tianshun Lian, Arvinder Singh, Daniel J Kosman, and James W Kronstad PLoS Pathog. 2008 February; 4(2): e45. Published online 2008 February 15. doi: 10.1371/journal.ppat.0040045.PMCID: PMC2242830 A Mycobacterial Enzyme Essential for Cell Division Synergizes with Resuscitation-Promoting Factor Erik C. Hett, Michael C. Chao, Lynn L. Deng, and Eric J. Rubin PLoS Pathog. 2008 February; 4(2): e1000001. Published online 2008 February 29. doi: 10.1371/journal.ppat.1000001.PMCID: PMC2262848 Evolution of a TRIM5-CypA Splice Isoform in Old World Monkeys Ruchi M. Newman, Laura Hall, Andrea Kirmaier, Lu-Ann Pozzi, Erez Pery, Michael Farzan, Shawn P. O'Neil, and Welkin Johnson PLoS Pathog. 2008 February; 4(2): e1000003. Published online 2008 February 29. doi: 10.1371/journal.ppat.1000003.PMCID: PMC2279257 IL-10 from CD4+CD25−Foxp3−CD127− Adaptive Regulatory T Cells Modulates Parasite Clearance and Pathology during Malaria Infection Kevin N. Couper, Daniel G. Blount, Mark S. Wilson, Julius C. Hafalla, Yasmine Belkaid, Masahito Kamanaka, Richard A. Flavell, J. Brian de Souza, and Eleanor M. Riley PLoS Pathog. 2008 February; 4(2): e1000004. Published online 2008 February 29. doi: 10.1371/journal.ppat.1000004.PMCID: PMC2291447 Interleukin-6 Is Crucial for Recall of Influenza-Specific Memory CD4+ T Cells Maria Paula Longhi, Kate Wright, Sarah N. Lauder, Mari A. Nowell, Gareth W. Jones, Andrew J. Godkin, Simon A. Jones, and Awen M. Gallimore PLoS Pathog. 2008 February; 4(2): e1000006. Published online 2008 February 29. doi: 10.1371/journal.ppat.1000006.PMCID: PMC2279258 The Interferon Response Inhibits HIV Particle Production by Induction of TRIM22 Stephen D. Barr, James R. Smiley, and Frederic D. Bushman PLoS Pathog. 2008 February; 4(2): e1000007. Published online 2008 February 29. doi: 10.1371/journal.ppat.1000007.PMCID: PMC2279259 Adenylyl Cyclase α and cAMP Signaling Mediate Plasmodium Sporozoite Apical Regulated Exocytosis and Hepatocyte Infection Takeshi Ono, Laura Cabrita-Santos, Ricardo Leitao, Esther Bettiol, Lisa A. Purcell, Olga Diaz-Pulido, Lucy B. Andrews, Takushi Tadakuma, Purnima Bhanot, Maria M. Mota, and Ana Rodriguez PLoS Pathog. 2008 February; 4(2): e1000008. Published online 2008 February 29. doi: 10.1371/journal.ppat.1000008.PMCID: PMC2279260 An RND-Type Efflux System in Borrelia burgdorferi Is Involved in Virulence and Resistance to Antimicrobial Compounds Ignas Bunikis, Katrin Denker, Yngve Östberg, Christian Andersen, Roland Benz, and Sven Bergström PLoS Pathog. 2008 February; 4(2): e1000009. Published online 2008 February 29. doi: 10.1371/journal.ppat.1000009.PMCID: PMC2279261 Hepatocyte Permissiveness to Plasmodium Infection Is Conveyed by a Short and Structurally Conserved Region of the CD81 Large Extracellular Domain Samir Yalaoui, Sergine Zougbédé, Stéphanie Charrin, Olivier Silvie, Cécile Arduise, Khemais Farhati, Claude Boucheix, Dominique Mazier, Eric Rubinstein, and Patrick Froissard PLoS Pathog. 2008 February; 4(2): e1000010. Published online 2008 February 29. doi: 10.1371/journal.ppat.1000010.PMCID: PMC2279262 Metagenomic Analysis of Human Diarrhea: Viral Detection and Discovery Stacy R. Finkbeiner, Adam F. Allred, Phillip I. Tarr, Eileen J. Klein, Carl D. Kirkwood, and David Wang PLoS Pathog. 2008 February; 4(2): e1000011. Published online 2008 February 29. doi: 10.1371/journal.ppat.1000011.PMCID: PMC2290972 Multiple Reassortment Events in the Evolutionary History of H1N1 Influenza A Virus Since 1918 Martha I. Nelson, Cécile Viboud, Lone Simonsen, Ryan T. Bennett, Sara B. Griesemer, Kirsten St. George, Jill Taylor, David J. Spiro, Naomi A. Sengamalay, Elodie Ghedin, Jeffery K. Taubenberger, and Edward C. Holmes PLoS Pathog. 2008 February; 4(2): e1000012. Published online 2008 February 29. doi: 10.1371/journal.ppat.1000012.PMCID: PMC2262849 Activation of Invariant NKT Cells Exacerbates Experimental Visceral Leishmaniasis Amanda C. Stanley, Yonghong Zhou, Fiona H. Amante, Louise M. Randall, Ashraful Haque, Daniel G. Pellicci, Geoff R. Hill, Mark J. Smyth, Dale I. Godfrey, and Christian R. Engwerda PLoS Pathog. 2008 February; 4(2): e1000028. Published online 2008 February 29. doi: 10.1371/journal.ppat.1000028.PMCID: PMC2265425 |