| | This journal provides immediate access to some articles. Articles Affinity enhancement of an in vivo matured therapeutic antibody using structure-based computational design Louis A. Clark, P. Ann Boriack-Sjodin, John Eldredge, Christopher Fitch, Bethany Friedman, Karl J.M. Hanf, Matthew Jarpe, Stefano F. Liparoto, You Li, Alexey Lugovskoy, Stephan Miller, Mia Rushe, Woody Sherman, Kenneth Simon, and Herman Van Vlijmen PMCID: PMC2242497 Expression, purification, and characterization of Thermotoga maritima membrane proteins for structure determination Linda Columbus, Jan Lipfert, Heath Klock, Ian Millett, Sebastian Doniach, and Scott A. Lesley PMCID: PMC2242514 3-Nitrotyrosine as a spectroscopic probe for investigating protein protein interactions Vincenzo De Filippis, Roberta Frasson, and Angelo Fontana PMCID: PMC2242503 Comparison of crystal structures of human androgen receptor ligand-binding domain complexed with various agonists reveals molecular determinants responsible for binding affinity Karine Pereira de Jésus-Tran, Pierre-Luc Côté, Line Cantin, Jonathan Blanchet, Fernand Labrie, and Rock Breton PMCID: PMC2242507 The contribution of the residues from the main hydrophobic core of ribonuclease A to its pressure-folding transition state Josep Font, Antoni Benito, Reinhard Lange, Marc Ribó, and Maria Vilanova PMCID: PMC2242501 Solution structure of the antifreeze-like domain of human sialic acid synthase Toshiyuki Hamada, Yoko Ito, Takamasa Abe, Fumiaki Hayashi, Peter Güntert, Makoto Inoue, Takanori Kigawa, Takaho Terada, Mikako Shirouzu, Mayumi Yoshida, Akiko Tanaka, Sumio Sugano, Shigeyuki Yokoyama, and Hiroshi Hirota PMCID: PMC2242509 An algorithm for predicting protein–protein interaction sites: Abnormally exposed amino acid residues and secondary structure elements Jemima Hoskins, Simon Lovell, and Tom L. Blundell PMCID: PMC2242518 Solution structure of Asl1650, an acyl carrier protein from Anabaena sp. PCC 7120 with a variant phosphopantetheinylation-site sequence Margaret A. Johnson, Wolfgang Peti, Torsten Herrmann, Ian A. Wilson, and Kurt Wüthrich PMCID: PMC2242512 The C-terminal domain of the transcriptional corepressor CtBP is intrinsically unstructured Marco Nardini, Dmitri Svergun, Peter V. Konarev, Stefania Spanò, Mauro Fasano, Chiara Bracco, Alessandra Pesce, Alessandra Donadini, Claudia Cericola, Francesco Secundo, Alberto Luini, Daniela Corda, and Martino Bolognesi PMCID: PMC2242513 Src kinase activation: A switched electrostatic network Elif Ozkirimli and Carol Beth Post PMCID: PMC2242506 Modulation of protein aggregation by polyethylene glycol conjugation: GCSF as a case study Rahul S. Rajan, Tiansheng Li, Mohini Aras, Christopher Sloey, Weston Sutherland, Hiromi Arai, Robert Briddell, Olaf Kinstler, Alexis M.K. Lueras, Yu Zhang, Heather Yeghnazar, Michael Treuheit, and David N. Brems PMCID: PMC2242524 Modular organization of FDH: Exploring the basis of hydrolase catalysis Steven N. Reuland, Alexander P. Vlasov, and Sergey A. Krupenko PMCID: PMC2242502 Sequential reorganization of β-sheet topology by insertion of a single strand Martin Sagermann, Walter A. Baase, and Brian W. Matthews PMCID: PMC2242519 Calorimetric and structural studies of the nitric oxide carrier S-nitrosoglutathione bound to human glutathione transferase P1-1 Ramiro Téllez-Sanz, Eleonora Cesareo, Marzia Nuccetelli, Ana M. Aguilera, Carmen Barón, Lorien J. Parker, Julian J. Adams, Craig J. Morton, Mario Lo Bello, Michael W. Parker, and Luis García-Fuentes PMCID: PMC2242504 Tunnel plasticity and quaternary structural integrity of a pentameric protein ring Kenneth J. Woycechowsky, Florian P. Seebeck, and Donald Hilvert PMCID: PMC2242520 Enhancing functional production of G protein-coupled receptors in Pichia pastoris to levels required for structural studies via a single expression screen Nicolas André, Nadia Cherouati, Cécile Prual, Tania Steffan, Gabrielle Zeder-Lutz, Thierry Magnin, Franc Pattus, Hartmut Michel, Renaud Wagner, and Christoph Reinhart PMCID: PMC2242496 Secondary structure, orientation, and oligomerization of phospholemman, a cardiac transmembrane protein Andrew J. Beevers and Andreas Kukol PMCID: PMC2242498 Inhibition of insulin fibrillogenesis with targeted peptides Todd J. Gibson and Regina M. Murphy PMCID: PMC2242521 Structure and dynamics of the epidermal growth factor receptor C-terminal phosphorylation domain Nam Y. Lee, Theodore L. Hazlett, and John G. Koland PMCID: PMC2242510 Stoichiometry of lipid interactions with transmembrane proteins—Deduced from the 3D structures Tibor Páli, Denys Bashtovyy, and Derek Marsh PMCID: PMC2242517 Secondary structure and dynamics of micelle bound β- and γ-synuclein Yoon-hui Sung and David Eliezer PMCID: PMC2242515 Probing the collective vibrational dynamics of a protein in liquid water by terahertz absorption spectroscopy Jing Xu, Kevin W. Plaxco, and S. James Allen PMCID: PMC2242499 Protein Structure Reports Structure of the Sir3 protein bromo adjacent homology (BAH) domain from S. cerevisiae at 1.95 Å resolution Zhonggang Hou, John R. Danzer, Catherine A. Fox, and James L. Keck PMCID: PMC2242508 Crystal structure of the conserved protein TTHA0727 from Thermus thermophilus HB8 at 1.9 Å resolution: A CMD family member distinct from carboxymuconolactone decarboxylase (CMD) and AhpD Kaori Ito, Ryoichi Arai, Emiko Fusatomi, Tomomi Kamo-Uchikubo, Shin-ichi Kawaguchi, Ryogo Akasaka, Takaho Terada, Seiki Kuramitsu, Mikako Shirouzu, and Shigeyuki Yokoyama PMCID: PMC2242516 For the Record Ligand binding by TPR domains Aitziber L. Cortajarena and Lynne Regan PMCID: PMC2242500 Crystal structure of human peptidoglycan recognition protein Iα bound to a muramyl pentapeptide from Gram-positive bacteria Rongjin Guan, Patrick H. Brown, Chittoor P. Swaminathan, Abhijit Roychowdhury, Geert-Jan Boons, and Roy A. Mariuzza PMCID: PMC2242522 The IclR family of transcriptional activators and repressors can be defined by a single profile Tino Krell, Antonio Jesús Molina-Henares, and Juan Luis Ramos PMCID: PMC2242505 pK values of the ionizable groups of proteins Richard L. Thurlkill, Gerald R. Grimsley, J. Martin Scholtz, and C. Nick Pace PMCID: PMC2242523 Award Address 2005 Emil Thomas Kaiser Award Ronald T. Raines PMCID: PMC2242511 |
