Editorial

Design of a minimal protein oligomerization domain by a structural approach.

Cysteine-independent polymerization of metallothioneins in solutions and in crystals.

Automated search of natively folded protein fragments for high-throughput structure determination in structural genomics.

Thermodynamic and structural characterization of Asn and Ala residues in the disallowed II' region of the Ramachandran plot.

Structural comparison of Ntn-hydrolases.

Beta-helix core packing within the triple-stranded oligomerization domain of the P22 tailspike.

Functional prediction: identification of protein orthologs and paralogs.

Backbone dynamics of sequence specific recognition and binding by the yeast Pho4 bHLH domain probed by NMR.

Evolution of binding affinity in a WW domain probed by phage display.

Stability and peptide binding specificity of Btk SH2 domain: molecular basis for X-linked agammaglobulinemia.

Delineation of the calcineurin-interacting region of cyclophilin B.

The effects of disulfide bonds on the denatured state of barnase.

Chaperonin-assisted folding of glutamine synthetase under nonpermissive conditions: off-pathway aggregation propensity does not determine the co-chaperonin requirement.

Thermal stability of Clostridium pasteurianum rubredoxin: deconvoluting the contributions of the metal site and the protein.

Fibers of tau fragments, but not full length tau, exhibit a cross beta-structure: implications for the formation of paired helical filaments.

Presence of closely spaced protein thiols on the surface of mammalian cells.

Resonant mirror biosensor analysis of type Ialpha cAMP-dependent protein kinase B domain--cyclic nucleotide interactions.

The design of a hyperstable mutant of the Abp1p SH3 domain by sequence alignment analysis.

Thirty-plus functional families from a single motif.

Enhancement by Mg2+ of domain specificity in Ca2+-dependent interactions of calmodulin with target sequences.

Structural changes in alpha-synuclein affect its chaperone-like activity in vitro.

Characterization of the interface structure of enzyme-inhibitor complex by using hydrogen-deuterium exchange and electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry.

Methylene as a possible universal footprinting reagent that will include hydrophobic surface areas: overview and feasibility: properties of diazirine as a precursor.

An improved tripod amphiphile for membrane protein solubilization.

Rationale for Bcl-xL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies.

Ab initio molecular dynamics studies on HIV-1 reverse transcriptase triphosphate binding site: implications for nucleoside-analog drug resistance.

N-terminal mutations in the anti-estradiol Fab 57-2 modify its hapten binding properties.

The structure of the yrdC gene product from Escherichia coli reveals a new fold and suggests a role in RNA binding.

A single amino acid substitution affects substrate specificity in cysteine proteinases from Fasciola hepatica.

Fluorescence and 19F NMR evidence that phenylalanine, 3-L-fluorophenylalanine and 4-L-fluorophenylalanine bind to the L-leucine specific receptor of Escherichia coli.

Effect of deamidation on folding of ribonuclease A.