| | This journal provides immediate access to some articles. Research Articles All in the family: structural and evolutionary relationships among three modular proteins with diverse functions and variable assembly. M. Bergdoll, L. D. Eltis, A. D. Cameron, P. Dumas, and J. T. Bolin PMCID: PMC2144073 Improving the binding affinity of an antibody using molecular modeling and site-directed mutagenesis. C. L. Casipit, R. Tal, V. Wittman, P. A. Chavaillaz, K. Arbuthnott, J. A. Weidanz, J. A. Jiao, and H. C. Wong PMCID: PMC2144089 Correlation between the 1.6 A crystal structure and mutational analysis of keratinocyte growth factor. T. D. Osslund, R. Syed, E. Singer, E. W. Hsu, R. Nybo, B. L. Chen, T. Harvey, T. Arakawa, L. O. Narhi, A. Chirino, and C. F. Morris PMCID: PMC2144086 Binding of a substrate analog to a domain swapping protein: X-ray structure of the complex of bovine seminal ribonuclease with uridylyl(2',5')adenosine. L. Vitagliano, S. Adinolfi, A. Riccio, F. Sica, A. Zagari, and L. Mazzarella PMCID: PMC2144088 Analysis of zinc binding sites in protein crystal structures. I. L. Alberts, K. Nadassy, and S. J. Wodak PMCID: PMC2144076 Thermodynamics of the reconstitution of tuna cytochrome c from two peptide fragments. A. Yokota, H. Takenaka, T. Oh, Y. Noda, and S. Segawa PMCID: PMC2144077 Role of P225 and the C136-C201 disulfide bond in tissue plasminogen activator. A. Vindigni and E. Di Cera PMCID: PMC2144078 Role of the 6-20 disulfide bridge in the structure and activity of epidermal growth factor. K. J. Barnham, A. M. Torres, D. Alewood, P. F. Alewood, T. Domagala, E. C. Nice, and R. S. Norton PMCID: PMC2144085 Molecular mechanisms of resistance: free energy calculations of mutation effects on inhibitor binding to HIV-1 protease. S. W. Rick, I. A. Topol, J. W. Erickson, and S. K. Burt PMCID: PMC2144074 Probing enzyme quaternary structure by combinatorial mutagenesis and selection. G. MacBeath, P. Kast, and D. Hilvert PMCID: PMC2144083 Enzyme-mononucleotide interactions: three different folds share common structural elements for ATP recognition. K. A. Denessiouk, J. V. Lehtonen, and M. S. Johnson PMCID: PMC2144091 Selecting near-native conformations in homology modeling: the role of molecular mechanics and solvation terms. A. Janardhan and S. Vajda PMCID: PMC2144075 The role of the 6 lysines and the terminal amine of Escherichia coli single-strand binding protein in its binding of single-stranded DNA. J. Chen, D. L. Smith, and M. A. Griep PMCID: PMC2144092 The magnitude of changes in guanidine-HCl unfolding m-values in the protein, iso-1-cytochrome c, depends upon the substructure containing the mutation. B. Hammack, K. Attfield, D. Clayton, E. Dec, A. Dong, C. Sarisky, and B. E. Bowler PMCID: PMC2144081 Efficient sequence analysis of the six gene products (7-74 kDa) from the Escherichia coli thiamin biosynthetic operon by tandem high-resolution mass spectrometry. N. L. Kelleher, S. V. Taylor, D. Grannis, C. Kinsland, H. J. Chiu, T. P. Begley, and F. W. McLafferty PMCID: PMC2144080 Aromatic L-amino acid decarboxylase: conformational change in the flexible region around Arg334 is required during the transaldimination process. S. Ishii, H. Hayashi, A. Okamoto, and H. Kagamiyama PMCID: PMC2144087 Opposite behavior of two isozymes when refolding in the presence of non-ionic detergents. F. Doñate, A. Artigues, A. Iriarte, and M. Martinez-Carrion PMCID: PMC2144090 Turn scanning by site-directed mutagenesis: application to the protein folding problem using the intestinal fatty acid binding protein. K. Kim and C. Frieden PMCID: PMC2144079 A superfamily of metalloenzymes unifies phosphopentomutase and cofactor-independent phosphoglycerate mutase with alkaline phosphatases and sulfatases. M. Y. Galperin, A. Bairoch, and E. V. Koonin PMCID: PMC2144072 Crystallization of recombinant human heme oxygenase-1. D. J. Schuller, A. Wilks, P. Ortiz de Montellano, and T. L. Poulos PMCID: PMC2144071 Overexpression of recombinant proteins with a C-terminal thiocarboxylate: implications for protein semisynthesis and thiamin biosynthesis. C. Kinsland, S. V. Taylor, N. L. Kelleher, F. W. McLafferty, and T. P. Begley PMCID: PMC2144084 Identification of a Frizzled-like cysteine rich domain in the extracellular region of developmental receptor tyrosine kinases. J. Saldanha, J. Singh, and D. Mahadevan PMCID: PMC2144082 Corrects: J. Saldanha, et al. Identification of a Frizzled-like cysteine rich domain in the extracellular region of developmental receptor tyrosine kinases. Protein Sci. 1998 August; 7(8): 1632–1635. |
