Things to Come

Sequence analysis of peptide mixtures by automated integration of Edman and mass spectrometric data.

Active site mutants of human cyclophilin A separate peptidyl-prolyl isomerase activity from cyclosporin A binding and calcineurin inhibition.

Multiple phosphate positions in the catalytic site of glycogen phosphorylase: structure of the pyridoxal-5'-pyrophosphate coenzyme-substrate analog.

Control of phosphorylase b conformation by a modified cofactor: crystallographic studies on R-state glycogen phosphorylase reconstituted with pyridoxal 5'-diphosphate.

Kinetic properties of tetrameric glycogen phosphorylase b in solution and in the crystalline state.

Steric exclusion is the principal source of the preferential hydration of proteins in the presence of polyethylene glycols.

Avian 3-hydroxy-3-methylglutaryl-CoA lyase: sensitivity of enzyme activity to thiol/disulfide exchange and identification of proximal reactive cysteines.

Three-dimensional structure of the Fab fragment of a neutralizing antibody to human rhinovirus serotype 2.

Structure of a rapidly formed intermediate in ribonuclease T1 folding.

Molecular dynamics studies of a DNA-binding protein: 1. A comparison of the trp repressor and trp aporepressor aqueous simulations.

Molecular dynamics studies of a DNA-binding protein: 2. An evaluation of implicit and explicit solvent models for the molecular dynamics simulation of the Escherichia coli trp repressor.

Expression, purification, and characterization of the functional dimeric cytoplasmic domain of human erythrocyte band 3 in Escherichia coli.

Accelerated high-sensitivity microsequencing of proteins and peptides using a miniature reaction cartridge.

A common domain within the proenzyme regions of the Drosophila snake and easter proteins and Tachypleus proclotting enzyme defines a new subfamily of serine proteases.