| | This journal provides immediate access to some articles. Commentary A genome-wide telomere screen in yeast: The long and short of it all Dawn Edmonds, Bobby-Joe Breitkreutz, and Lea Harrington PMCID: PMC470706 Physical Sciences Applied Physical Sciences Enthalpy arrays Francisco E. Torres, Peter Kuhn, Dirk De Bruyker, Alan G. Bell, Michal V. Wolkin, Eric Peeters, James R. Williamson, Gregory B. Anderson, Gregory P. Schmitz, Michael I. Recht, Sandra Schweizer, Lincoln G. Scott, Jackson H. Ho, Scott A. Elrod, Peter G. Schultz, Richard A. Lerner, and Richard H. Bruce PMCID: PMC470707 A bubble-driven microfluidic transport element for bioengineering Philippe Marmottant and Sascha Hilgenfeldt PMCID: PMC470708 Chemistry Peptide and protein sequence analysis by electron transfer dissociation mass spectrometry John E. P. Syka, Joshua J. Coon, Melanie J. Schroeder, Jeffrey Shabanowitz, and Donald F. Hunt PMCID: PMC470779 Engineering From the Cover:
Poly-β amino ester-containing microparticles enhance the activity of nonviral genetic vaccines Steven R. Little, David M. Lynn, Qing Ge, Daniel G. Anderson, Sidharth V. Puram, Jianzhu Chen, Herman N. Eisen, and Robert Langer PMCID: PMC470709 Geophysics Evidence for a significant urbanization effect on climate in China Liming Zhou, Robert E. Dickinson, Yuhong Tian, Jingyun Fang, Qingxiang Li, Robert K. Kaufmann, Compton J. Tucker, and Ranga B. Myneni PMCID: PMC470710 Physics Gravitational vacuum condensate stars Pawel O. Mazur and Emil Mottola PMCID: PMC470711 Biological Sciences Anthropology The broad spectrum revisited: Evidence from plant remains Ehud Weiss, Wilma Wetterstrom, Dani Nadel, and Ofer Bar-Yosef PMCID: PMC470712 Biochemistry Thermal-activated protein mobility and its correlation with catalysis in thermophilic alcohol dehydrogenase Zhao-Xun Liang, Thomas Lee, Katheryn A. Resing, Natalie G. Ahn, and Judith P. Klinman PMCID: PMC470713 Strand exchange activity of human recombination protein Rad52 Jaspal K. Kumar and Ravindra C. Gupta PMCID: PMC470714 Human and yeast Rad52 proteins promote DNA strand exchange Baoyuan Bi, Nataliya Rybalchenko, Efim I. Golub, and Charles M. Radding PMCID: PMC470715 Direct evidence that a conserved arginine in RuvB AAA+ ATPase acts as an allosteric effector for the ATPase activity of the adjacent subunit in a hexamer Takashi Hishida, Yong-Woon Han, Satoko Fujimoto, Hiroshi Iwasaki, and Hideo Shinagawa PMCID: PMC470716 Induction of interferon-stimulated gene expression and antiviral responses require protein deacetylase activity Hao-Ming Chang, Matthew Paulson, Michelle Holko, Charles M. Rice, Bryan R. G. Williams, Isabelle Marié, and David E. Levy PMCID: PMC470717 Identification of an evolutionarily divergent U11 small nuclear ribonucleoprotein particle in Drosophila Claudia Schneider, Cindy L. Will, Jürgen Brosius, Mikko J. Frilander, and Reinhard Lührmann PMCID: PMC470718 Biochemical and functional analysis of a 9-nt RNA sequence that affects translation efficiency in eukaryotic cells Stephen A. Chappell, Gerald M. Edelman, and Vincent P. Mauro PMCID: PMC470719 Crystal structure of elongation factor P from Thermus thermophilus HB8 Kyoko Hanawa-Suetsugu, Shun-ichi Sekine, Hiroaki Sakai, Chie Hori-Takemoto, Takaho Terada, Satoru Unzai, Jeremy R. H. Tame, Seiki Kuramitsu, Mikako Shirouzu, and Shigeyuki Yokoyama PMCID: PMC470720 Sex pheromone of the pink hibiscus mealybug, Maconellicoccus hirsutus, contains an unusual cyclobutanoid monoterpene Aijun Zhang, Divina Amalin, Shyam Shirali, Miguel S. Serrano, Rosa A. Franqui, James E. Oliver, Jerome A. Klun, Jeffrey R. Aldrich, Dale E. Meyerdirk, and Stephen L. Lapointe PMCID: PMC470721 Commitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineage Qi-Qun Tang, Tamara C. Otto, and M. Daniel Lane PMCID: PMC470722 Biophysics A fluorescence resonance energy transfer-derived structure of a quantum dot-protein bioconjugate nanoassembly I. L. Medintz, J. H. Konnert, A. R. Clapp, I. Stanish, M. E. Twigg, H. Mattoussi, J. M. Mauro, and J. R. Deschamps PMCID: PMC470723 From the Cover:
The integral membrane enzyme PagP alternates between two dynamically distinct states Peter M. Hwang, Russell E. Bishop, and Lewis E. Kay PMCID: PMC470724 Crystal structure of phosphodiesterase 9 shows orientation variation of inhibitor 3-isobutyl-1-methylxanthine binding Qing Huai, Huanchen Wang, Wei Zhang, Robert W. Colman, Howard Robinson, and Hengming Ke PMCID: PMC470725 A one-headed class V myosin molecule develops multiple large (≈32-nm) steps successively Tomonobu M. Watanabe, Hiroto Tanaka, Atsuko Hikikoshi Iwane, Saori Maki-Yonekura, Kazuaki Homma, Akira Inoue, Reiko Ikebe, Toshio Yanagida, and Mitsuo Ikebe PMCID: PMC470726 Relating microstructure to rheology of a bundled and cross-linked F-actin network in vitro J. H. Shin, M. L. Gardel, L. Mahadevan, P. Matsudaira, and D. A. Weitz PMCID: PMC470727 G-matrix Fourier transform NMR spectroscopy for complete protein resonance assignment Hanudatta S. Atreya and Thomas Szyperski PMCID: PMC470728 Cell Biology Targeting expression of expanded polyglutamine proteins to the endoplasmic reticulum or mitochondria prevents their aggregation Erwann Rousseau, Benjamin Dehay, Léa Ben-Haïem, Yvon Trottier, Michel Morange, and Anne Bertolotti PMCID: PMC470729 Methionine sulfoxide reductase A is important for lens cell viability and resistance to oxidative stress Marc Kantorow, John R. Hawse, Tracy L. Cowell, Sonia Benhamed, Gresin O. Pizarro, Venkat N. Reddy, and J. F. Hejtmancik PMCID: PMC470730 Simultaneous mapping of filamentous actin flow and turnover in migrating cells by quantitative fluorescent speckle microscopy Pascal Vallotton, Stephanie L. Gupton, Clare M. Waterman-Storer, and Gaudenz Danuser PMCID: PMC470731 A molecular link between SR protein dephosphorylation and mRNA export Yingqun Huang, Therese A. Yario, and Joan A. Steitz PMCID: PMC470732 ADP-ribosylation factor 6 regulates tumor cell invasion through the activation of the MEK/ERK signaling pathway Sarah E. Tague, Vandhana Muralidharan, and Crislyn D'Souza-Schorey PMCID: PMC470733 A-type lamins regulate retinoblastoma protein function by promoting subnuclear localization and preventing proteasomal degradation Brett R. Johnson, Ryan T. Nitta, Richard L. Frock, Leslie Mounkes, David A. Barbie, Colin L. Stewart, Ed Harlow, and Brian K. Kennedy PMCID: PMC470734 Cells release prions in association with exosomes Benoit Fevrier, Didier Vilette, Fabienne Archer, Damarys Loew, Wolfgang Faigle, Michel Vidal, Hubert Laude, and Graça Raposo PMCID: PMC470735 Ecology Fine-root production dominates response of a deciduous forest to atmospheric CO2 enrichment Richard J. Norby, Joanne Ledford, Carolyn D. Reilly, Nicole E. Miller, and Elizabeth G. O'Neill PMCID: PMC470736 The worldwide costs of marine protected areas Andrew Balmford, Pippa Gravestock, Neal Hockley, Colin J. McClean, and Callum M. Roberts PMCID: PMC470737 Evolution Hypoxic stress tolerance of the blind subterranean mole rat: Expression of erythropoietin and hypoxia-inducible factor 1α Imad Shams, Aaron Avivi, and Eviatar Nevo PMCID: PMC470738 Historical demography of Müllerian mimicry in the neotropical Heliconius butterflies N. S. Flanagan, A. Tobler, A. Davison, O. G. Pybus, D. D. Kapan, S. Planas, M. Linares, D. Heckel, and W. O. McMillan PMCID: PMC470739 Simple and complex nuclear loci created by newly transferred chloroplast DNA in tobacco Chun Y. Huang, Michael A. Ayliffe, and Jeremy N. Timmis PMCID: PMC470740 The louse-borne human pathogen Bartonella quintana is a genomic derivative of the zoonotic agent Bartonella henselae Cecilia M. Alsmark, A. Carolin Frank, E. Olof Karlberg, Boris-Antoine Legault, David H. Ardell, Björn Canbäck, Ann-Sofie Eriksson, A. Kristina Näslund, Scott A. Handley, Maxime Huvet, Bernard La Scola, Martin Holmberg, and Siv G. E. Andersson PMCID: PMC470741 Computational inference of scenarios for α-proteobacterial genome evolution Bastien Boussau, E. Olof Karlberg, A. Carolin Frank, Boris-Antoine Legault, and Siv G. E. Andersson PMCID: PMC470742 Genetics Painting of fourth in genus Drosophila suggests autosome-specific gene regulation Jan Larsson, Malin J. Svensson, Per Stenberg, and Maria Mäkitalo PMCID: PMC470743 Unexpected complexity in the haplotypes of commonly used inbred strains of laboratory mice B. Yalcin, J. Fullerton, S. Miller, D. A. Keays, S. Brady, A. Bhomra, A. Jefferson, E. Volpi, R. R. Copley, J. Flint, and R. Mott PMCID: PMC470780 An oligonucleotide microchip for genome-wide microRNA profiling in human and mouse tissues Chang-Gong Liu, George Adrian Calin, Brian Meloon, Nir Gamliel, Cinzia Sevignani, Manuela Ferracin, Calin Dan Dumitru, Masayoshi Shimizu, Simona Zupo, Mariella Dono, Hansjuerg Alder, Florencia Bullrich, Massimo Negrini, and Carlo M. Croce PMCID: PMC470744 Immunology From the Cover:
Poly-β amino ester-containing microparticles enhance the activity of nonviral genetic vaccines Steven R. Little, David M. Lynn, Qing Ge, Daniel G. Anderson, Sidharth V. Puram, Jianzhu Chen, Herman N. Eisen, and Robert Langer PMCID: PMC470709 From the Cover:
Phospholipases C and A2 control lysosome-mediated IL-1β secretion: Implications for inflammatory processes Cristina Andrei, Paola Margiocco, Alessandro Poggi, Lavinia V. Lotti, M. R. Torrisi, and Anna Rubartelli PMCID: PMC470745 Medical Sciences Targeted disruption of Nrf2 causes regenerative immune-mediated hemolytic anemia Jong-Min Lee, Kaimin Chan, Yuet Wai Kan, and Jeffrey A. Johnson PMCID: PMC470746 Functional variants within the secreted frizzled-related protein 3 gene are associated with hip osteoarthritis in females John Loughlin, Barbara Dowling, Kay Chapman, Lucy Marcelline, Zehra Mustafa, Lorraine Southam, Athena Ferreira, Cathleen Ciesielski, Dennis A. Carson, and Maripat Corr PMCID: PMC470747 Pulmonary delivery of an erythropoietin Fc fusion protein in non-human primates through an immunoglobulin transport pathway Alan J. Bitonti, Jennifer A. Dumont, Susan C. Low, Robert T. Peters, Keith E. Kropp, Vito J. Palombella, James M. Stattel, Yichun Lu, Cristina A. Tan, Jeffrey J. Song, Ana Maria Garcia, Neil E. Simister, Gerburg M. Spiekermann, Wayne I. Lencer, and Richard S. Blumberg PMCID: PMC470748 Tumor regionality in the mouse intestine reflects the mechanism of loss of Apc function Kevin M. Haigis, Peter D. Hoff, Alanna White, Alex R. Shoemaker, Richard B. Halberg, and William F. Dove PMCID: PMC470749 ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins Nan Wang, Debin Lan, Wengen Chen, Fumihiko Matsuura, and Alan R. Tall PMCID: PMC470750 Microbiology Microarray analysis of transposition targets in Escherichia coli: The impact of transcription Dipankar Manna, Adam M. Breier, and N. Patrick Higgins PMCID: PMC470751 Complete genomes of two clinical Staphylococcus aureus strains: Evidence for the rapid evolution of virulence and drug resistance Matthew T. G. Holden, Edward J. Feil, Jodi A. Lindsay, Sharon J. Peacock, Nicholas P. J. Day, Mark C. Enright, Tim J. Foster, Catrin E. Moore, Laurence Hurst, Rebecca Atkin, Andrew Barron, Nathalie Bason, Stephen D. Bentley, Carol Chillingworth, Tracey Chillingworth, Carol Churcher, Louise Clark, Craig Corton, Ann Cronin, Jon Doggett, Linda Dowd, Theresa Feltwell, Zahra Hance, Barbara Harris, Heidi Hauser, Simon Holroyd, Kay Jagels, Keith D. James, Nicola Lennard, Alexandra Line, Rebecca Mayes, Sharon Moule, Karen Mungall, Douglas Ormond, Michael A. Quail, Ester Rabbinowitsch, Kim Rutherford, Mandy Sanders, Sarah Sharp, Mark Simmonds, Kim Stevens, Sally Whitehead, Bart G. Barrell, Brian G. Spratt, and Julian Parkhill PMCID: PMC470752 Identification of tandem duplicate regulatory small RNAs in Pseudomonas aeruginosa involved in iron homeostasis Paula J. Wilderman, Nathaniel A. Sowa, David J. FitzGerald, Peter C. FitzGerald, Susan Gottesman, Urs A. Ochsner, and Michael L. Vasil PMCID: PMC470753 Identification of a domain within the multifunctional Vibrio cholerae RTX toxin that covalently cross-links actin Kerri-Lynn Sheahan, Christina L. Cordero, and Karla J. Fullner Satchell PMCID: PMC470754 Contributions of the structural proteins of severe acute respiratory syndrome coronavirus to protective immunity Ursula J. Buchholz, Alexander Bukreyev, Lijuan Yang, Elaine W. Lamirande, Brian R. Murphy, Kanta Subbarao, and Peter L. Collins PMCID: PMC470755 Neuroscience Contribution of inhibitory mechanisms to direction selectivity and response normalization in macaque middle temporal area A. Thiele, C. Distler, H. Korbmacher, and K.-P. Hoffmann PMCID: PMC470756 From the Cover:
Prolonged hyperpolarizing potentials precede spindle oscillations in the thalamic reticular nucleus Pablo Fuentealba, Igor Timofeev, and Mircea Steriade PMCID: PMC470757 Nicotinic receptors regulate the survival of newborn neurons in the adult olfactory bulb Naguib Mechawar, Armen Saghatelyan, Régis Grailhe, Linda Scoriels, Gilles Gheusi, Marie-Madeleine Gabellec, Pierre-Marie Lledo, and Jean-Pierre Changeux PMCID: PMC470758 Repetition suppression of faces is modulated by emotion Alumit Ishai, Luiz Pessoa, Philip C. Bikle, and Leslie G. Ungerleider PMCID: PMC470759 Insulin-like growth factor I is required for vessel remodeling in the adult brain C. Lopez-Lopez, D. LeRoith, and I. Torres-Aleman PMCID: PMC470760 The loss function of sensorimotor learning Konrad Paul Körding and Daniel M. Wolpert PMCID: PMC470761 The role of iron and copper molecules in the neuronal vulnerability of locus coeruleus and substantia nigra during aging Luigi Zecca, Antonella Stroppolo, Alberto Gatti, Davide Tampellini, Marco Toscani, Mario Gallorini, Giuseppe Giaveri, Paolo Arosio, Paolo Santambrogio, Ruggero G. Fariello, Erdem Karatekin, Mark H. Kleinman, Nicholas Turro, Oleh Hornykiewicz, and Fabio A. Zucca PMCID: PMC470762 Beta oscillations in a large-scale sensorimotor cortical network: Directional influences revealed by Granger causality Andrea Brovelli, Mingzhou Ding, Anders Ledberg, Yonghong Chen, Richard Nakamura, and Steven L. Bressler PMCID: PMC470781 Acute neuroprotective synergy of erythropoietin and insulin-like growth factor I Murat Digicaylioglu, Gwenn Garden, Sonia Timberlake, Lauren Fletcher, and Stuart A. Lipton PMCID: PMC470763 Pharmacology The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam Berkley A. Lynch, Nathalie Lambeng, Karl Nocka, Patricia Kensel-Hammes, Sandra M. Bajjalieh, Alain Matagne, and Bruno Fuks PMCID: PMC470764 Delivery of therapeutic levels of heparin and low-molecular-weight heparin through a pulmonary route Yiwei Qi, Ganlin Zhao, Dongfang Liu, Zachary Shriver, Mallik Sundaram, Shiladitya Sengupta, Ganesh Venkataraman, Robert Langer, and Ram Sasisekharan PMCID: PMC470765 Plant Biology An Arabidopsis homeodomain transcription factor gene, HOS9, mediates cold tolerance through a CBF-independent pathway Jianhua Zhu, Huazhong Shi, Byeong-ha Lee, Barbara Damsz, Shie Cheng, Vicki Stirm, Jian-Kang Zhu, Paul M. Hasegawa, and Ray A. Bressan PMCID: PMC470766 Protein kinase CK2 modulates developmental functions of the abscisic acid responsive protein Rab17 from maize Marta Riera, Mercè Figueras, Cristina López, Adela Goday, and Montserrat Pagès PMCID: PMC470767 Long-range patterns of diversity and linkage disequilibrium surrounding the maize Y1 gene are indicative of an asymmetric selective sweep Kelly Palaisa, Michele Morgante, Scott Tingey, and Antoni Rafalski PMCID: PMC470768 Comparative mapping and marker-assisted selection in Rosaceae fruit crops Elisabeth Dirlewanger, Enrique Graziano, Tarek Joobeur, Francesc Garriga-Calderé, Patrick Cosson, Werner Howad, and Pere Arús PMCID: PMC470769 Manipulation of light signal transduction as a means of modifying fruit nutritional quality in tomato Yongsheng Liu, Sherry Roof, Zhibiao Ye, Cornelius Barry, Ageeth van Tuinen, Julia Vrebalov, Chris Bowler, and Jim Giovannoni PMCID: PMC470770 Ancient polyploidization predating divergence of the cereals, and its consequences for comparative genomics A. H. Paterson, J. E. Bowers, and B. A. Chapman PMCID: PMC470771 Modulation of the polyamine biosynthetic pathway in transgenic rice confers tolerance to drought stress Teresa Capell, Ludovic Bassie, and Paul Christou PMCID: PMC470772 Diversity Arrays Technology (DArT) for whole-genome profiling of barley Peter Wenzl, Jason Carling, David Kudrna, Damian Jaccoud, Eric Huttner, Andris Kleinhofs, and Andrzej Kilian PMCID: PMC470773 From the Cover:
Dissecting the maize genome by using chromosome addition and radiation hybrid lines Ralf G. Kynast, Ron J. Okagaki, Mark W. Galatowitsch, Shannon R. Granath, Morrison S. Jacobs, Adrian O. Stec, Howard W. Rines, and Ronald L. Phillips PMCID: PMC470774 A family of conserved bacterial effectors inhibits salicylic acid-mediated basal immunity and promotes disease necrosis in plants Sruti DebRoy, Roger Thilmony, Yong-Bum Kwack, Kinya Nomura, and Sheng Yang He PMCID: PMC470775 Psychology Extrageniculate mediation of unconscious vision in transcranial magnetic stimulation-induced blindsight Tony Ro, Dominique Shelton, Olivia L. Lee, and Erik Chang PMCID: PMC470776 Social Sciences Anthropology Environment, agriculture, and settlement patterns in a marginal Polynesian landscape P. V. Kirch, A. S. Hartshorn, O. A. Chadwick, P. M. Vitousek, D. R. Sherrod, J. Coil, L. Holm, and W. D. Sharp PMCID: PMC470777 Psychology Learning problems, delayed development, and puberty Beverly A. Wright and Steven G. Zecker PMCID: PMC470778 |
