| | This journal provides immediate access to some articles. This Week in PNAS Proc Natl Acad Sci U S A. 2007 May 15; 104(20): 8197–8198. doi: 10.1073/iti2007104.PMCID: PMC1895925 Commentaries From rhomboid function to structure and back again Raquel L. Lieberman and Michael S. Wolfe PMCID: PMC1895926 Climate change implicated in amphibian and lizard declines David B. Wake PMCID: PMC1895927 Mutations in clusters and showers John W. Drake PMCID: PMC1895928 Subtype-selective sodium channel blockers promise a new era of pain research Birgit T. Priest and Gregory J. Kaczorowski PMCID: PMC1895929 Physical Sciences Applied Physical Sciences Single-molecule mass spectrometry in solution using a solitary nanopore Joseph W. F. Robertson, Claudio G. Rodrigues, Vincent M. Stanford, Kenneth A. Rubinson, Oleg V. Krasilnikov, and John J. Kasianowicz PMCID: PMC1866312 The directed cooperative assembly of proteorhodopsin into 2D and 3D polarized arrays Hongjun Liang, Gregg Whited, Chi Nguyen, and Galen D. Stucky PMCID: PMC1895931 Chemistry A cell nanoinjector based on carbon nanotubes Xing Chen, Andras Kis, A. Zettl, and Carolyn R. Bertozzi PMCID: PMC1895932 Array feature size influences nucleic acid surface capture in DNA microarrays David S. Dandy, Peng Wu, and David W. Grainger PMCID: PMC1895933 Engineering A kinematic description of the trajectories of Listeria monocytogenes propelled by actin comet tails V. B. Shenoy, D. T. Tambe, A. Prasad, and J. A. Theriot PMCID: PMC1895934 Biological Sciences Applied Biological Sciences APEx 2-hybrid, a quantitative protein–protein interaction assay for antibody discovery and engineering Ki Jun Jeong, Min Jeong Seo, Brent L. Iverson, and George Georgiou PMCID: PMC1895937 Prandiology of Drosophila and the CAFE assay William W. Ja, Gil B. Carvalho, Elizabeth M. Mak, Noelle N. de la Rosa, Annie Y. Fang, Jonathan C. Liong, Ted Brummel, and Seymour Benzer PMCID: PMC1899109 Biochemistry From the Cover:
Enzymatic analysis of a rhomboid intramembrane protease implicates transmembrane helix 5 as the lateral substrate gate Rosanna P. Baker, Keith Young, Liang Feng, Yigong Shi, and Sinisa Urban PMCID: PMC1895938 Contribution of hydrophobic and electrostatic interactions to the membrane integration of the Shaker K+ channel voltage sensor domain Liyan Zhang, Yoko Sato, Tara Hessa, Gunnar von Heijne, Jong-Kook Lee, Itsuo Kodama, Masao Sakaguchi, and Nobuyuki Uozumi PMCID: PMC1899110 Directed evolution of gene-shuffled IFN-α molecules with activity profiles tailored for treatment of chronic viral diseases Amy D. Brideau-Andersen, Xiaojian Huang, Siu-Chi Chang Sun, Teddy T. Chen, Diane Stark, Ian J. Sas, Linda Zadik, Glenn N. Dawes, Douglas R. Guptill, Robert McCord, Sridhar Govindarajan, Ajoy Roy, Shumin Yang, Judy Gao, Yong Hong Chen, Niels Jørgen Ø. Skartved, Annette K. Pedersen, David Lin, Christopher P. Locher, Indrani Rebbapragada, Anne Dam Jensen, Steven H. Bass, Torben L. Straight Nissen, Sridhar Viswanathan, Graham R. Foster, Julian A. Symons, and Phillip A. Patten PMCID: PMC1895939 Allosteric regulation of an essential trypanosome polyamine biosynthetic enzyme by a catalytically dead homolog Erin K. Willert, Richard Fitzpatrick, and Margaret A. Phillips PMCID: PMC1895940 Biophysics Single-molecule mass spectrometry in solution using a solitary nanopore Joseph W. F. Robertson, Claudio G. Rodrigues, Vincent M. Stanford, Kenneth A. Rubinson, Oleg V. Krasilnikov, and John J. Kasianowicz PMCID: PMC1866312 A kinematic description of the trajectories of Listeria monocytogenes propelled by actin comet tails V. B. Shenoy, D. T. Tambe, A. Prasad, and J. A. Theriot PMCID: PMC1895934 Rigidity-driven growth and migration of epithelial cells on microstructured anisotropic substrates Alexandre Saez, Marion Ghibaudo, Axel Buguin, Pascal Silberzan, and Benoît Ladoux PMCID: PMC1895941 From the Cover:
Müller cells are living optical fibers in the vertebrate retina Kristian Franze, Jens Grosche, Serguei N. Skatchkov, Stefan Schinkinger, Christian Foja, Detlev Schild, Ortrud Uckermann, Kort Travis, Andreas Reichenbach, and Jochen Guck PMCID: PMC1895942 Structural basis for functional mimicry of long-variable-arm tRNA by transfer-messenger RNA Yoshitaka Bessho, Rie Shibata, Shun-ichi Sekine, Kazutaka Murayama, Kyoko Higashijima, Chie Hori-Takemoto, Mikako Shirouzu, Seiki Kuramitsu, and Shigeyuki Yokoyama PMCID: PMC1895943 Stabilization of RAD-51–DNA filaments via an interaction domain in Caenorhabditis elegans BRCA2 Mark I. R. Petalcorin, Vitold E. Galkin, Xiong Yu, Edward H. Egelman, and Simon J. Boulton PMCID: PMC1895944 Crystal structure of the Sec4p·Sec2p complex in the nucleotide exchanging intermediate state Yusuke Sato, Shuya Fukai, Ryuichiro Ishitani, and Osamu Nureki PMCID: PMC1895945 Intrinsic disorder as a mechanism to optimize allosteric coupling in proteins Vincent J. Hilser and E. Brad Thompson PMCID: PMC1895946 Inhibiting HIV-1 integrase by shifting its oligomerization equilibrium Zvi Hayouka, Joseph Rosenbluh, Aviad Levin, Shoshana Loya, Mario Lebendiker, Dmitry Veprintsev, Moshe Kotler, Amnon Hizi, Abraham Loyter, and Assaf Friedler PMCID: PMC1895947 Cell Biology A cell nanoinjector based on carbon nanotubes Xing Chen, Andras Kis, A. Zettl, and Carolyn R. Bertozzi PMCID: PMC1895932 Opening of connexin 43 hemichannels is increased by lowering intracellular redox potential Mauricio A. Retamal, Kurt A. Schalper, Kenji F. Shoji, Michael V. L. Bennett, and Juan C. Sáez PMCID: PMC1895948 Profiling signaling polarity in chemotactic cells Yingchun Wang, Shi-Jian Ding, Wei Wang, Jon M. Jacobs, Wei-Jun Qian, Ronald J. Moore, Feng Yang, David G. Camp, II, Richard D. Smith, and Richard L. Klemke PMCID: PMC1895949 Surveillance mechanism linking Bub1 loss to the p53 pathway Ole V. Gjoerup, Jiaping Wu, Devin Chandler-Militello, Grace L. Williams, Jean Zhao, Brian Schaffhausen, Parmjit S. Jat, and Thomas M. Roberts PMCID: PMC1895950 Developmental Biology Decondensing the protamine domain for transcription Rui Pires Martins and Stephen A. Krawetz PMCID: PMC1895951 The conserved transcriptome in human and rodent male gametogenesis Frédéric Chalmel, Antoine D. Rolland, Christa Niederhauser-Wiederkehr, Sanny S. W. Chung, Philippe Demougin, Alexandre Gattiker, James Moore, Jean-Jacques Patard, Debra J. Wolgemuth, Bernard Jégou, and Michael Primig PMCID: PMC1864911 Ecology From the Cover:
Amphibian and reptile declines over 35 years at La Selva, Costa Rica Steven M. Whitfield, Kristen E. Bell, Thomas Philippi, Mahmood Sasa, Federico Bolaños, Gerardo Chaves, Jay M. Savage, and Maureen A. Donnelly PMCID: PMC1895953 Evolutionary responses of discontinuous gas exchange in insects Craig R. White, Tim M. Blackburn, John S. Terblanche, Elrike Marais, Marc Gibernau, and Steven L. Chown PMCID: PMC1895954 Trophic cascade facilitates coral recruitment in a marine reserve Peter J. Mumby, Alastair R. Harborne, Jodene Williams, Carrie V. Kappel, Daniel R. Brumbaugh, Fiorenza Micheli, Katherine E. Holmes, Craig P. Dahlgren, Claire B. Paris, and Paul G. Blackwell PMCID: PMC1895955 Habitat specialization, body size, and family identity explain lepidopteran density–area relationships in a cross-continental comparison Peter A. Hambäck, Keith S. Summerville, Ingolf Steffan-Dewenter, Jochen Krauss, Göran Englund, and Thomas O. Crist PMCID: PMC1895956 Multitrophic interaction facilitates parasite–host relationship between an invasive beetle and the honey bee Baldwyn Torto, Drion G. Boucias, Richard T. Arbogast, James H. Tumlinson, and Peter E. A. Teal PMCID: PMC1895957 Evolution Evolution of nematode-trapping cells of predatory fungi of the Orbiliaceae based on evidence from rRNA-encoding DNA and multiprotein sequences Ying Yang, Ence Yang, Zhiqiang An, and Xingzhong Liu PMCID: PMC1895958 The neoselectionist theory of genome evolution Giorgio Bernardi PMCID: PMC1866311 Intracellular targeting of telomeric retrotransposon Gag proteins of distantly related Drosophila species Elena Casacuberta, Fernando Azorín Marín, and Mary-Lou Pardue PMCID: PMC1895960 Independent sorting-out of thousands of duplicated gene pairs in two yeast species descended from a whole-genome duplication Devin R. Scannell, A. Carolin Frank, Gavin C. Conant, Kevin P. Byrne, Megan Woolfit, and Kenneth H. Wolfe PMCID: PMC1895961 Genetics From the Cover:
Evidence for mutation showers Jicheng Wang, Kelly D. Gonzalez, William A. Scaringe, Kimberly Tsai, Ning Liu, Dongqing Gu, Wenyan Li, Kathleen A. Hill, and Steve S. Sommer PMCID: PMC1895962 Activation-induced cytidine deaminase action is strongly stimulated by mutations of the THO complex Belén Gómez-González and Andrés Aguilera PMCID: PMC1895963 Immunology Low-intensity transplant regimens facilitate recruitment of donor-specific regulatory T cells that promote hematopoietic engraftment Ling Weng, Julian Dyson, and Francesco Dazzi PMCID: PMC1895964 A silent chemokine receptor regulates steady-state leukocyte homing in vivo Kornelia Heinzel, Claudia Benz, and Conrad C. Bleul PMCID: PMC1895965 Immunization with hepatitis C virus-like particles results in control of hepatitis C virus infection in chimpanzees Gamal A. Elmowalid, Ming Qiao, Sook-Hyang Jeong, Brian B. Borg, Thomas F. Baumert, Ronda K. Sapp, Zongyi Hu, Krishna Murthy, and T. Jake Liang PMCID: PMC1895966 Agalactosylated IgG antibodies depend on cellular Fc receptors for in vivo activity Falk Nimmerjahn, Robert M. Anthony, and Jeffrey V. Ravetch PMCID: PMC1895967 Medical Sciences Activated Cdc42-associated kinase Ack1 promotes prostate cancer progression via androgen receptor tyrosine phosphorylation Nupam P. Mahajan, Yuanbo Liu, Samarpan Majumder, Maria R. Warren, Carol E. Parker, James L. Mohler, H. Shelton Earp, and Young E. Whang PMCID: PMC1895968 Effective therapy of murine models of human leukemia and lymphoma with radiolabeled anti-CD30 antibody, HeFi-1 Meili Zhang, Zhengsheng Yao, Hiral Patel, Kayhan Garmestani, Zhuo Zhang, Vladimir S. Talanov, Paul S. Plascjak, Carolyn K. Goldman, John E. Janik, Martin W. Brechbiel, and Thomas A. Waldmann PMCID: PMC1895969 Hepatitis C virus epitope-specific neutralizing antibodies in Igs prepared from human plasma Pei Zhang, Charles G. Wu, Kathleen Mihalik, Maria Luisa Virata-Theimer, Mei-ying W. Yu, Harvey J. Alter, and Stephen M. Feinstone PMCID: PMC1866310 Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists Matthias Lauth, Åsa Bergström, Takashi Shimokawa, and Rune Toftgård PMCID: PMC1866313 Gene-trapped mouse embryonic stem cell-derived cardiac myocytes and human genetics implicate AKAP10 in heart rhythm regulation Whittemore G. Tingley, Ludmila Pawlikowska, Jonathan G. Zaroff, Taeryn Kim, Trieu Nguyen, Stephen G. Young, Karen Vranizan, Pui-Yan Kwok, Mary A. Whooley, and Bruce R. Conklin PMCID: PMC1866184 HIV-1 escape from the entry-inhibiting effects of a cholesterol-binding compound via cleavage of gp41 by the viral protease Abdul A. Waheed, Sherimay D. Ablan, James D. Roser, Raymond C. Sowder, Carl P. Schaffner, Elena Chertova, and Eric O. Freed PMCID: PMC1895973 Microbiology Simple sequence repeats in prokaryotic genomes Jan Mrázek, Xiangxue Guo, and Apurva Shah PMCID: PMC1895974 Synthesis of glycerol phosphate lipoteichoic acid in Staphylococcus aureus Angelika Gründling and Olaf Schneewind PMCID: PMC1895975 Integrated network analysis identifies nitric oxide response networks and dihydroxyacid dehydratase as a crucial target in Escherichia coli Daniel R. Hyduke, Laura R. Jarboe, Linh M. Tran, Katherine J. Y. Chou, and James C. Liao PMCID: PMC1895976 Neuroscience Neural interactions between flicker-induced self-organized visual hallucinations and physical stimuli Vincent A. Billock and Brian H. Tsou PMCID: PMC1895977 Triggering sleep slow waves by transcranial magnetic stimulation Marcello Massimini, Fabio Ferrarelli, Steve K. Esser, Brady A. Riedner, Reto Huber, Michael Murphy, Michael J. Peterson, and Giulio Tononi PMCID: PMC1895978 Caspase-9 regulates apoptosis/proliferation balance during metamorphic brain remodeling in Xenopus Laurent Coen, Karine Le Blay, Isaline Rowe, and Barbara A. Demeneix PMCID: PMC1895979 ApoER2/VLDL receptor and Dab1 in the rostral migratory stream function in postnatal neuronal migration independently of Reelin Nuno Andrade, Vukoslav Komnenovic, Sophia M. Blake, Yves Jossin, Brian Howell, Andre Goffinet, Wolfgang J. Schneider, and Johannes Nimpf PMCID: PMC1895980 Carbonic anhydrase XIV deficiency produces a functional defect in the retinal light response Judith Mosinger Ogilvie, Kevin K. Ohlemiller, Gul N. Shah, Barbara Ulmasov, Timothy A. Becker, Abdul Waheed, Anne K. Hennig, Peter D. Lukasiewicz, and William S. Sly PMCID: PMC1895981 Pharmacology From the Cover:
A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat Michael F. Jarvis, Prisca Honore, Char-Chang Shieh, Mark Chapman, Shailen Joshi, Xu-Feng Zhang, Michael Kort, William Carroll, Brian Marron, Robert Atkinson, James Thomas, Dong Liu, Michael Krambis, Yi Liu, Steve McGaraughty, Katharine Chu, Rosemarie Roeloffs, Chengmin Zhong, Joseph P. Mikusa, Gricelda Hernandez, Donna Gauvin, Carrie Wade, Chang Zhu, Madhavi Pai, Marc Scanio, Lei Shi, Irene Drizin, Robert Gregg, Mark Matulenko, Ahmed Hakeem, Michael Gross, Matthew Johnson, Kennan Marsh, P. Kay Wagoner, James P. Sullivan, Connie R. Faltynek, and Douglas S. Krafte PMCID: PMC1895982 Unique antiviral mechanism discovered in anti-hepatitis B virus research with a natural product analogue Chunxiao Ying, Ying Li, Chung-Hang Leung, Michael D. Robek, and Yung-Chi Cheng PMCID: PMC1895983 Plant Biology A secretory pathway-localized cation diffusion facilitator confers plant manganese tolerance Edgar Peiter, Barbara Montanini, Anthony Gobert, Pai Pedas, Søren Husted, Frans J. M. Maathuis, Damien Blaudez, Michel Chalot, and Dale Sanders PMCID: PMC1895984 A substrate-independent, 14:3:3 protein-mediated plastid import pathway of NADPH:protochlorophyllide oxidoreductase A Andreas Schemenewitz, Stephan Pollmann, Christiane Reinbothe, and Steffen Reinbothe PMCID: PMC1895985 Helical microtubule arrays in a collection of twisting tubulin mutants of Arabidopsis thaliana Takashi Ishida, Yayoi Kaneko, Megumi Iwano, and Takashi Hashimoto PMCID: PMC1895986 A gene from the cellulose synthase-like C family encodes a β-1,4 glucan synthase Jean-Christophe Cocuron, Olivier Lerouxel, Georgia Drakakaki, Ana P. Alonso, Aaron H. Liepman, Kenneth Keegstra, Natasha Raikhel, and Curtis G. Wilkerson PMCID: PMC1895987 Psychology Temporal-callosal pathway diffusivity predicts phonological skills in children Robert F. Dougherty, Michal Ben-Shachar, Gayle K. Deutsch, Arvel Hernandez, Glenn R. Fox, and Brian A. Wandell PMCID: PMC1895988 Social Sciences Psychology The neural basis of the interaction between theory of mind and moral judgment Liane Young, Fiery Cushman, Marc Hauser, and Rebecca Saxe PMCID: PMC1895935 Effect of congenital blindness on the semantic representation of some everyday concepts Andrew C. Connolly, Lila R. Gleitman, and Sharon L. Thompson-Schill PMCID: PMC1895936 Neural interactions between flicker-induced self-organized visual hallucinations and physical stimuli Vincent A. Billock and Brian H. Tsou PMCID: PMC1895977 |
