| | This journal provides immediate access to some articles. This Week in PNAS Proc Natl Acad Sci U S A. 2007 June 12; 104(24): 9913–9914. doi: 10.1073/iti2407104.PMCID: PMC1891226 Commentaries Evaluating a technological fix for climate Peter G. Brewer PMCID: PMC1891232 Imaging protein–protein interactions in plants and single cells David Morse PMCID: PMC1891236 Physical Sciences Applied Mathematics Madden–Julian Oscillation analog and intraseasonal variability in a multicloud model above the equator Andrew J. Majda, Samuel N. Stechmann, and Boualem Khouider PMCID: PMC1885818 Applied Physical Sciences Mechanical limits of viral capsids Mathias Buenemann and Peter Lenz PMCID: PMC1891220 Chemistry Influence of base stacking on excited-state behavior of polyadenine in water, based on time-dependent density functional calculations F. Santoro, V. Barone, and R. Improta PMCID: PMC1891264 Cooperative light-induced molecular movements of highly ordered azobenzene self-assembled monolayers Giuseppina Pace, Violetta Ferri, Christian Grave, Mark Elbing, Carsten von Hänisch, Michael Zharnikov, Marcel Mayor, Maria Anita Rampi, and Paolo Samorì PMCID: PMC1891213 Computer Sciences From the Cover:
Automated reverse engineering of nonlinear dynamical systems Josh Bongard and Hod Lipson PMCID: PMC1891254 Environmental Sciences From the Cover:
Transient climate–carbon simulations of planetary geoengineering H. Damon Matthews and Ken Caldeira PMCID: PMC1885819 Physics Intrinsic dephasing in one-dimensional ultracold atom interferometers R. Bistritzer and E. Altman PMCID: PMC1891245 Six closely related YbT2Zn20 (T = Fe, Co, Ru, Rh, Os, Ir) heavy fermion compounds with large local moment degeneracy M. S. Torikachvili, S. Jia, E. D. Mun, S. T. Hannahs, R. C. Black, W. K. Neils, Dinesh Martien, S. L. Bud'ko, and P. C. Canfield PMCID: PMC1891250 Biological Sciences Applied Biological Sciences From the Cover:
Automated reverse engineering of nonlinear dynamical systems Josh Bongard and Hod Lipson PMCID: PMC1891254 nanos gene control DNA mediates developmentally regulated transposition in the yellow fever mosquito Aedes aegypti Zach N. Adelman, Nijole Jasinskiene, Sedef Onal, Jennifer Juhn, Aurora Ashikyan, Michael Salampessy, Todd MacCauley, and Anthony A. James PMCID: PMC1891237 Biochemistry Long-range structural effects of a Charcot–Marie–Tooth disease-causing mutation in human glycyl-tRNA synthetase Wei Xie, Leslie A. Nangle, Wei Zhang, Paul Schimmel, and Xiang-Lei Yang PMCID: PMC1891255 Receptor-mediated activation of nitric oxide synthesis by arginine in endothelial cells Mahesh S. Joshi, T. Bruce Ferguson, Jr., Fruzsina K. Johnson, Robert A. Johnson, Sampath Parthasarathy, and Jack R. Lancaster, Jr. PMCID: PMC1891228 Structure of a receptor-binding fragment of reelin and mutational analysis reveal a recognition mechanism similar to endocytic receptors Norihisa Yasui, Terukazu Nogi, Tomoe Kitao, Yoshimi Nakano, Mitsuharu Hattori, and Junichi Takagi PMCID: PMC1891246 Load-dependent mechanism of nonmuscle myosin 2 Mihály Kovács, Kavitha Thirumurugan, Peter J. Knight, and James R. Sellers PMCID: PMC1885822 Global distribution of negative cofactor 2 subunit-α on human promoters Thomas K. Albert, Korbinian Grote, Stefan Boeing, Gertraud Stelzer, Aloys Schepers, and Michael Meisterernst PMCID: PMC1891239 Lithocholic acid can carry out in vivo functions of vitamin D Jamie A. Nehring, Claudia Zierold, and Hector F. DeLuca PMCID: PMC1891258 Bone morphogenetic protein 1 processes prolactin to a 17-kDa antiangiogenic factor Gaoxiang Ge, Cecilia A. Fernández, Marsha A. Moses, and Daniel S. Greenspan PMCID: PMC1891225 Biophysics Influence of base stacking on excited-state behavior of polyadenine in water, based on time-dependent density functional calculations F. Santoro, V. Barone, and R. Improta PMCID: PMC1891264 Kinetics and thermodynamics of amyloid formation from direct measurements of fluctuations in fibril mass Tuomas P. J. Knowles, Wenmiao Shu, Glyn L. Devlin, Sarah Meehan, Stefan Auer, Christopher M. Dobson, and Mark E. Welland PMCID: PMC1891240 Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases Rey-Ting Guo, Rong Cao, Po-Huang Liang, Tzu-Ping Ko, Tao-Hsin Chang, Michael P. Hudock, Wen-Yih Jeng, Cammy K.-M. Chen, Yonghui Zhang, Yongcheng Song, Chih-Jung Kuo, Fenglin Yin, Eric Oldfield, and Andrew H.-J. Wang PMCID: PMC1877987 Structural and thermodynamic characterization of a cytoplasmic dynein light chain–intermediate chain complex John C. Williams, Petra L. Roulhac, Anindya G. Roy, Richard B. Vallee, Michael C. Fitzgerald, and Wayne A. Hendrickson PMCID: PMC1885999 Three-dimensional structure of a human connexin26 gap junction channel reveals a plug in the vestibule Atsunori Oshima, Kazutoshi Tani, Yoko Hiroaki, Yoshinori Fujiyoshi, and Gina E. Sosinsky PMCID: PMC1886001 Molecular dynamics using atomic-resolution structure reveal structural fluctuations that may lead to polymerization of human Cu–Zn superoxide dismutase Richard W. Strange, Chin W. Yong, William Smith, and S. Samar Hasnain PMCID: PMC1885824 Cell Biology Huntingtin facilitates dynein/dynactin-mediated vesicle transport Juliane P. Caviston, Jennifer L. Ross, Sheila M. Antony, Mariko Tokito, and Erika L. F. Holzbaur PMCID: PMC1891230 Inhibition of ubiquitin-mediated degradation of MOAP-1 by apoptotic stimuli promotes Bax function in mitochondria Nai Yang Fu, Sunil K. Sukumaran, and Victor C. Yu PMCID: PMC1877986 Fragile X mental retardation protein FMRP and the RNA export factor NXF2 associate with and destabilize Nxf1 mRNA in neuronal cells Meiqin Zhang, Qiaoqiao Wang, and Yingqun Huang PMCID: PMC1891223 Loss of a quiescent niche but not follicle stem cells in the absence of bone morphogenetic protein signaling Krzysztof Kobielak, Nicole Stokes, June de la Cruz, Lisa Polak, and Elaine Fuchs PMCID: PMC1888574 Mesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like breast cancers Sendurai A. Mani, Jing Yang, Mary Brooks, Gunda Schwaninger, Alicia Zhou, Naoyuki Miura, Jeffery L. Kutok, Kimberly Hartwell, Andrea L. Richardson, and Robert A. Weinberg PMCID: PMC1891217 Ecology Comparative support for the niche variation hypothesis that more generalized populations also are more heterogeneous Daniel I. Bolnick, Richard Svanbäck, Márcio S. Araújo, and Lennart Persson PMCID: PMC1891261 Evolution The selection of acceptable protein mutations Rajkumar Sasidharan and Cyrus Chothia PMCID: PMC1891269 Evolution of robustness in the signaling network of Pristionchus vulva development Hans Zauner and Ralf J. Sommer PMCID: PMC1891216 From the Cover:
Major Caribbean and Central American frog faunas originated by ancient oceanic dispersal Matthew P. Heinicke, William E. Duellman, and S. Blair Hedges PMCID: PMC1891260 Stochastic innovation as a mechanism by which catalysts might self-assemble into chemical reaction networks Justin A. Bradford and Ken A. Dill PMCID: PMC1891208 Genetics Inducible XIST-dependent X-chromosome inactivation in human somatic cells is reversible Jennifer C. Chow, Lisa L. Hall, Sarah E. L. Baldry, Nancy P. Thorogood, Jeanne B. Lawrence, and Carolyn J. Brown PMCID: PMC1891207 Systematic prediction and validation of breakpoints associated with copy-number variants in the human genome Jan O. Korbel, Alexander Eckehart Urban, Fabian Grubert, Jiang Du, Thomas E. Royce, Peter Starr, Guoneng Zhong, Beverly S. Emanuel, Sherman M. Weissman, Michael Snyder, and Mark B. Gerstein PMCID: PMC1891248 Identifying pattern-defined regulatory islands in mammalian genomes Tom H. Cheung, Kristen K. B. Barthel, Yin Lam Kwan, and Xuedong Liu PMCID: PMC1891267 Immunology Differential homing mechanisms regulate regionalized effector CD8αβ+ T cell accumulation within the small intestine Hanna Stenstad, Marcus Svensson, Helena Cucak, Knut Kotarsky, and William W. Agace PMCID: PMC1891238 Structural elucidation of the m157 mouse cytomegalovirus ligand for Ly49 natural killer cell receptors Erin J. Adams, Z. Sean Juo, Rayna Takaki Venook, Martin J. Boulanger, Hisashi Arase, Lewis L. Lanier, and K. Christopher Garcia PMCID: PMC1891256 Medical Sciences Nuclear relocation of the nephrin and CD2AP-binding protein dendrin promotes apoptosis of podocytes Katsuhiko Asanuma, Kirk Nicholas Campbell, Kwanghee Kim, Christian Faul, and Peter Mundel PMCID: PMC1891229 The A-kinase anchoring protein (AKAP)-Lbc-signaling complex mediates α1 adrenergic receptor-induced cardiomyocyte hypertrophy Aline Appert-Collin, Susanna Cotecchia, Monique Nenniger-Tosato, Thierry Pedrazzini, and Dario Diviani PMCID: PMC1891209 Central histamine H3 receptor signaling negatively regulates susceptibility to autoimmune inflammatory disease of the CNS Cory Teuscher, Meena Subramanian, Rajkumar Noubade, Jian Feng Gao, Halina Offner, James F. Zachary, and Elizabeth P. Blankenhorn PMCID: PMC1891222 Alternating electric fields arrest cell proliferation in animal tumor models and human brain tumors Eilon D. Kirson, Vladimír Dbalý, František Tovaryš, Josef Vymazal, Jean F. Soustiel, Aviran Itzhaki, Daniel Mordechovich, Shirley Steinberg-Shapira, Zoya Gurvich, Rosa Schneiderman, Yoram Wasserman, Marc Salzberg, Bernhard Ryffel, Dorit Goldsher, Erez Dekel, and Yoram Palti PMCID: PMC1886002 Phenotypic characterization of human colorectal cancer stem cells Piero Dalerba, Scott J. Dylla, In-Kyung Park, Rui Liu, Xinhao Wang, Robert W. Cho, Timothy Hoey, Austin Gurney, Emina H. Huang, Diane M. Simeone, Andrew A. Shelton, Giorgio Parmiani, Chiara Castelli, and Michael F. Clarke PMCID: PMC1891215 Regulation of the GABA cell phenotype in hippocampus of schizophrenics and bipolars Francine M. Benes, Benjamin Lim, David Matzilevich, John P. Walsh, Sivan Subburaju, and Martin Minns PMCID: PMC1888575 Monotherapy with a tumor-targeting mutant of Salmonella typhimurium cures orthotopic metastatic mouse models of human prostate cancer Ming Zhao, Jack Geller, Huaiyu Ma, Meng Yang, Sheldon Penman, and Robert M. Hoffman PMCID: PMC1891231 TORC2 regulates germinal center repression of the TCL1 oncoprotein to promote B cell development and inhibit transformation Ali I. Kuraishy, Samuel W. French, Mara Sherman, Marco Herling, Dan Jones, Randolph Wall, and Michael A. Teitell PMCID: PMC1891214 Microbiology Discovery of parasite virulence genes reveals a unique regulator of chromosome condensation 1 ortholog critical for efficient nuclear trafficking Matthew B. Frankel, Dana G. Mordue, and Laura J. Knoll PMCID: PMC1891257 Herpes simplex virus glycoproteins gB and gH function in fusion between the virion envelope and the outer nuclear membrane Aaron Farnsworth, Todd W. Wisner, Michael Webb, Richard Roller, Gary Cohen, Roselyn Eisenberg, and David C. Johnson PMCID: PMC1891206 Extensively cross-reactive anti-HIV-1 neutralizing antibodies induced by gp140 immunization Peng Fei Zhang, Fatim Cham, Ming Dong, Anil Choudhary, Peter Bouma, Zhiqiang Zhang, Yiming Shao, Yan-Ru Feng, Lemin Wang, Nathalie Mathy, Gerald Voss, Christopher C. Broder, and Gerald V. Quinnan, Jr PMCID: PMC1885220 Nitric oxide inhibits Shiga-toxin synthesis by enterohemorrhagic Escherichia coli Marjolaine Vareille, Thibaut de Sablet, Thomas Hindré, Christine Martin, and Alain P. Gobert PMCID: PMC1891265 Involvement of host cellular multivesicular body functions in hepatitis B virus budding Tokiko Watanabe, Ericka M. Sorensen, Akira Naito, Meghan Schott, Seungtaek Kim, and Paul Ahlquist PMCID: PMC1891263 Neuroscience Long-term monitoring of transplanted human neural stem cells in developmental and pathological contexts with MRI Raphael Guzman, Nobuko Uchida, Tonya M. Bliss, Dongping He, Karen K. Christopherson, David Stellwagen, Alexandra Capela, Joan Greve, Robert C. Malenka, Michael E. Moseley, Theo D. Palmer, and Gary K. Steinberg PMCID: PMC1891235 Alarin is a vasoactive peptide Radmila Santic, Sabine M. Schmidhuber, Roland Lang, Isabella Rauch, Elena Voglas, Nicole Eberhard, Johann W. Bauer, Susan D. Brain, and Barbara Kofler PMCID: PMC1891251 Ventrolateral prefrontal cortex and tactile memory disambiguation in the human brain Penelope Kostopoulos, Marie-Claire Albanese, and Michael Petrides PMCID: PMC1891227 Robust coding of flow-field parameters by axo-axonal gap junctions between fly visual interneurons Hermann Cuntz, Juergen Haag, Friedrich Forstner, Idan Segev, and Alexander Borst PMCID: PMC1886000 Rapid bulk endocytosis and its kinetics of fission pore closure at a central synapse Wei Wu and Ling-Gang Wu PMCID: PMC1891249 Network structure of cerebral cortex shapes functional connectivity on multiple time scales Christopher J. Honey, Rolf Kötter, Michael Breakspear, and Olaf Sporns PMCID: PMC1891224 Dissection of the components for PIP2 activation and thermosensation in TRP channels Sebastian Brauchi, Gerardo Orta, Carolina Mascayano, Marcelo Salazar, Natalia Raddatz, Hector Urbina, Eduardo Rosenmann, Fernando Gonzalez-Nilo, and Ramon Latorre PMCID: PMC1891241 Stepwise proteolysis liberates tau fragments that nucleate the Alzheimer-like aggregation of full-length tau in a neuronal cell model Y. P. Wang, J. Biernat, M. Pickhardt, E. Mandelkow, and E.-M. Mandelkow PMCID: PMC1891218 Dopaminergic modulation of short-term synaptic plasticity at striatal inhibitory synapses Fatuel Tecuapetla, Luis Carrillo-Reid, José Bargas, and Elvira Galarraga PMCID: PMC1885397 Plant Biology From the Cover:
Imaging protein interactions with bioluminescence resonance energy transfer (BRET) in plant and mammalian cells and tissues Xiaodong Xu, Mohammed Soutto, Qiguang Xie, Stein Servick, Chitra Subramanian, Albrecht G. von Arnim, and Carl Hirschie Johnson PMCID: PMC1891211 EXECUTER1- and EXECUTER2-dependent transfer of stress-related signals from the plastid to the nucleus of Arabidopsis thaliana Keun Pyo Lee, Chanhong Kim, Frank Landgraf, and Klaus Apel PMCID: PMC1891253 Proteolysis of the barley receptor-like protein kinase RPG1 by a proteasome pathway is correlated with Rpg1-mediated stem rust resistance Jayaveeramuthu Nirmala, Stephanie Dahl, Brian J. Steffenson, C. Gamini Kannangara, Diter von Wettstein, Xianming Chen, and Andris Kleinhofs PMCID: PMC1891204 Sustainability Science Pesticides reduce symbiotic efficiency of nitrogen-fixing rhizobia and host plants Jennifer E. Fox, Jay Gulledge, Erika Engelhaupt, Matthew E. Burow, and John A. McLachlan PMCID: PMC1885820 Global and regional drivers of accelerating CO2 emissions Michael R. Raupach, Gregg Marland, Philippe Ciais, Corinne Le Quéré, Josep G. Canadell, Gernot Klepper, and Christopher B. Field PMCID: PMC1876160 Social Sciences Anthropology From the Cover:
82,000-year-old shell beads from North Africa and implications for the origins of modern human behavior Abdeljalil Bouzouggar, Nick Barton, Marian Vanhaeren, Francesco d'Errico, Simon Collcutt, Tom Higham, Edward Hodge, Simon Parfitt, Edward Rhodes, Jean-Luc Schwenninger, Chris Stringer, Elaine Turner, Steven Ward, Abdelkrim Moutmir, and Abdelhamid Stambouli PMCID: PMC1891266 |
