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Volume 4(2);  February 2006
Editorial
Science in the News
Hemai Parthasarathy
PLoS Biol. 2006 February; 4(2): e55. Published online 2006 February 14. doi: 10.1371/journal.pbio.0040055.
PMCID: PMC1363712
Synopses
A Novel Design Principle for the Insect Odorant Receptor
Liza Gross
PLoS Biol. 2006 February; 4(2): e34. Published online 2006 January 17. doi: 10.1371/journal.pbio.0040034.
PMCID: PMC1334238
Structural Insights into the Regulation of a Key Tumor Suppressor
Liza Gross
PLoS Biol. 2006 February; 4(2): e40. Published online 2006 January 17. doi: 10.1371/journal.pbio.0040040.
PMCID: PMC1334479
Looping Out Introns to Help Splicing
Richard Robinson
PLoS Biol. 2006 February; 4(2): e41. Published online 2006 January 10. doi: 10.1371/journal.pbio.0040041.
PMCID: PMC1326235
A New Window into Structural Plasticity in the Adult Visual Cortex
Liza Gross
PLoS Biol. 2006 February; 4(2): e42. Published online 2005 December 27. doi: 10.1371/journal.pbio.0040042.
PMCID: PMC1318479
Redundancy in Cortical Surface Vessels Supports Persistent Blood Flow
Liza Gross
PLoS Biol. 2006 February; 4(2): e43. Published online 2006 January 3. doi: 10.1371/journal.pbio.0040043.
PMCID: PMC1324795
The Sirt1 Gene Promotes Insulin Secretion in Accord with Diet
Françoise Chanut
PLoS Biol. 2006 February; 4(2): e44. Published online 2005 December 27. doi: 10.1371/journal.pbio.0040044.
PMCID: PMC1318480
Self-Generated Touch: A Neural Perspective
Liza Gross
PLoS Biol. 2006 February; 4(2): e48. Published online 2006 January 17. doi: 10.1371/journal.pbio.0040048.
PMCID: PMC1334239
Potassium Channels Rule over Insulin Release with an Ion Fist
Françoise Chanut
PLoS Biol. 2006 February; 4(2): e53. Published online 2006 January 17. doi: 10.1371/journal.pbio.0040053.
PMCID: PMC1334240
Genetic Evidence that Humans Have Pushed Orang-utans to the Brink of Extinction
Liza Gross
PLoS Biol. 2006 February; 4(2): e57. Published online 2006 January 24. doi: 10.1371/journal.pbio.0040057.
PMCID: PMC1334201
Protein Complexes Help Point Migrating Cells in the Right Direction
Liza Gross
PLoS Biol. 2006 February; 4(2): e58. Published online 2006 January 24. doi: 10.1371/journal.pbio.0040058.
PMCID: PMC1334200
A New Tile in the Biochemical Puzzle of Insulin Biology
Françoise Chanut
PLoS Biol. 2006 February; 4(2): e59. Published online 2006 January 31. doi: 10.1371/journal.pbio.0040059.
PMCID: PMC1351923
Feature
Pandemic Influenza: The Inside Story
Henry Nicholls
PLoS Biol. 2006 February; 4(2): e50. Published online 2006 February 14. doi: 10.1371/journal.pbio.0040050.
PMCID: PMC1363710
Unsolved Mystery
Autophagy: A Forty-Year Search for a Missing Membrane Source
Gabor Juhasz and Thomas P Neufeld
PLoS Biol. 2006 February; 4(2): e36. Published online 2006 February 14. doi: 10.1371/journal.pbio.0040036.
PMCID: PMC1363699
Book Review/Science in the Media
The Bittersweet Sounds of the Modern Food Chain
Gavin Yamey
PLoS Biol. 2006 February; 4(2): e47. Published online 2006 February 14. doi: 10.1371/journal.pbio.0040047.
PMCID: PMC1363707
Primer
Oscillations, Intercellular Coupling, and Insulin Secretion in Pancreatic β Cells
Patrick E MacDonald and Patrik Rorsman
PLoS Biol. 2006 February; 4(2): e49. Published online 2006 February 14. doi: 10.1371/journal.pbio.0040049.
PMCID: PMC1363709
Research Articles
Atypical Membrane Topology and Heteromeric Function of Drosophila Odorant Receptors In Vivo
Richard Benton, Silke Sachse, Stephen W Michnick, and Leslie B Vosshall
PLoS Biol. 2006 February; 4(2): e20. Published online 2006 January 17. doi: 10.1371/journal.pbio.0040020.
PMCID: PMC1334387
Intronic Binding Sites for hnRNP A/B and hnRNP F/H Proteins Stimulate Pre-mRNA Splicing
Rebeca Martinez-Contreras, Jean-François Fisette, Faiz-ul Hassan Nasim, Richard Madden, Mélanie Cordeau, and Benoit Chabot
PLoS Biol. 2006 February; 4(2): e21. Published online 2006 January 10. doi: 10.1371/journal.pbio.0040021.
PMCID: PMC1326234
Two-Photon Imaging of Cortical Surface Microvessels Reveals a Robust Redistribution in Blood Flow after Vascular Occlusion
Chris B Schaffer, Beth Friedman, Nozomi Nishimura, Lee F Schroeder, Philbert S Tsai, Ford F Ebner, Patrick D Lyden, and David Kleinfeld
PLoS Biol. 2006 February; 4(2): e22. Published online 2006 January 3. doi: 10.1371/journal.pbio.0040022.
PMCID: PMC1324794
Genetic Signature of Anthropogenic Population Collapse in Orang-utans
Benoît Goossens, Lounès Chikhi, Marc Ancrenaz, Isabelle Lackman-Ancrenaz, Patrick Andau, and Michael W Bruford
PLoS Biol. 2006 February; 4(2): e25. Published online 2006 January 24. doi: 10.1371/journal.pbio.0040025.
PMCID: PMC1334199
Critical Role of Gap Junction Coupled KATP Channel Activity for Regulated Insulin Secretion
Jonathan V Rocheleau, Maria S Remedi, Butch Granada, W. Steven Head, Joseph C Koster, Colin G Nichols, and David W Piston
PLoS Biol. 2006 February; 4(2): e26. Published online 2006 January 17. doi: 10.1371/journal.pbio.0040026.
PMCID: PMC1334237
Structural Basis of Competitive Recognition of p53 and MDM2 by HAUSP/USP7: Implications for the Regulation of the p53–MDM2 Pathway
Min Hu, Lichuan Gu, Muyang Li, Philip D Jeffrey, Wei Gu, and Yigong Shi
PLoS Biol. 2006 February; 4(2): e27. Published online 2006 January 17. doi: 10.1371/journal.pbio.0040027.
PMCID: PMC1334386
Attenuation of Self-Generated Tactile Sensations Is Predictive, not Postdictive
Paul M Bays, J. Randall Flanagan, and Daniel M Wolpert
PLoS Biol. 2006 February; 4(2): e28. Published online 2006 January 17. doi: 10.1371/journal.pbio.0040028.
PMCID: PMC1334241
Dynamic Remodeling of Dendritic Arbors in GABAergic Interneurons of Adult Visual Cortex
Wei-Chung Allen Lee, Hayden Huang, Guoping Feng, Joshua R Sanes, Emery N Brown, Peter T So, and Elly Nedivi
PLoS Biol. 2006 February; 4(2): e29. Published online 2005 December 27. doi: 10.1371/journal.pbio.0040029.
PMCID: PMC1318477
Sirt1 Regulates Insulin Secretion by Repressing UCP2 in Pancreatic β Cells
Laura Bordone, Maria Carla Motta, Frederic Picard, Ashley Robinson, Ulupi S Jhala, Javier Apfeld, Thomas McDonagh, Madeleine Lemieux, Michael McBurney, Akos Szilvasi, Erin J Easlon, Su-Ju Lin, and Leonard Guarente
PLoS Biol. 2006 February; 4(2): e31. Published online 2005 December 27. doi: 10.1371/journal.pbio.0040031.
PMCID: PMC1318478
Hem-1 Complexes Are Essential for Rac Activation, Actin Polymerization, and Myosin Regulation during Neutrophil Chemotaxis
Orion D Weiner, Maike C Rentel, Alex Ott, Glenn E Brown, Mark Jedrychowski, Michael B Yaffe, Steven P Gygi, Lewis C Cantley, Henry R Bourne, and Marc W Kirschner
PLoS Biol. 2006 February; 4(2): e38. Published online 2006 January 24. doi: 10.1371/journal.pbio.0040038.
PMCID: PMC1334198
Conditional Expression of Smad7 in Pancreatic β Cells Disrupts TGF-β Signaling and Induces Reversible Diabetes Mellitus
Nora G Smart, Åsa A Apelqvist, Xueying Gu, Erin B Harmon, James N Topper, Raymond J MacDonald, and Seung K Kim
PLoS Biol. 2006 February; 4(2): e39. Published online 2006 January 31. doi: 10.1371/journal.pbio.0040039.
PMCID: PMC1351925
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