| | This journal provides immediate access to some articles. In This Issue Proc Natl Acad Sci U S A. 2005 December 13; 102(50): 17883–17884. doi: 10.1073/iti5005102.PMCID: PMC1312368 Commentaries Pains, gains, and midbrains Anthony H. Dickenson, Lucy A. Bee, and Rie Suzuki PMCID: PMC1312401 Control of seed size in plants Venkatesan Sundaresan PMCID: PMC1312409 Huntington's disease and neurogenesis: FGF-2 to the rescue? Albert R. La Spada PMCID: PMC1312425 Physical Sciences Chemistry Tautomeric selectivity of the excited-state lifetime of guanine/cytosine base pairs: The role of electron-driven proton-transfer processes Andrzej L. Sobolewski, Wolfgang Domcke, and C. Hättig PMCID: PMC1312371 Observation and manipulation of subsurface hydride in Pd{111} and its effect on surface chemical, physical, and electronic properties E. Charles H. Sykes, Luis C. Fernández-Torres, Sanjini U. Nanayakkara, Brent A. Mantooth, Ryan M. Nevin, and Paul S. Weiss PMCID: PMC1312391 Changes in the chemical and dynamic properties of cardiac troponin T cause discrete cardiomyopathies in transgenic mice Briar R. Ertz-Berger, Huamei He, Candice Dowell, Stephen M. Factor, Todd E. Haim, Sara Nunez, Steven D. Schwartz, Joanne S. Ingwall, and Jil C. Tardiff PMCID: PMC1298915 Environmental Sciences INAUGURAL ARTICLE by a Recently Elected Academy Member: Simulation of Sahel drought in the 20th and 21st centuries I. M. Held, T. L. Delworth, J. Lu, K. L. Findell, and T. R. Knutson PMCID: PMC1312412 From the Cover:
Wildfires, complexity, and highly optimized tolerance Max A. Moritz, Marco E. Morais, Lora A. Summerell, J. M. Carlson, and John Doyle PMCID: PMC1312407 Geophysics Iron spin transition in Earth's mantle S. Speziale, A. Milner, V. E. Lee, S. M. Clark, M. P. Pasternak, and R. Jeanloz PMCID: PMC1312404 Biological Sciences Agricultural Sciences INAUGURAL ARTICLE by a Recently Elected Academy Member: Comparative nutrition and metabolism: Explication of open questions with emphasis on protein and amino acids David H. Baker PMCID: PMC1312430 Biochemistry From the Cover:
A human transporter protein that mediates the final excretion step for toxic organic cations Masato Otsuka, Takuya Matsumoto, Riyo Morimoto, Shigeo Arioka, Hiroshi Omote, and Yoshinori Moriyama PMCID: PMC1312386 Rotation scheme of V1-motor is different from that of F1-motor Hiromi Imamura, Mizuho Takeda, Saeko Funamoto, Katsuya Shimabukuro, Masasuke Yoshida, and Ken Yokoyama PMCID: PMC1306795 The heteromeric Nanoarchaeum equitans splicing endonuclease cleaves noncanonical bulge–helix–bulge motifs of joined tRNA halves Lennart Randau, Kate Calvin, Michelle Hall, Jing Yuan, Mircea Podar, Hong Li, and Dieter Söll PMCID: PMC1312423 Combining chemical genetics and proteomics to identify protein kinase substrates Noah Dephoure, Russell W. Howson, Justin D. Blethrow, Kevan M. Shokat, and Erin K. O'Shea PMCID: PMC1306798 Efficient growth inhibition of Bacillus anthracis by knocking out the ribonucleotide reductase tyrosyl radical Eduard Torrents, Margareta Sahlin, Daniele Biglino, Astrid Gräslund, and Britt-Marie Sjöberg PMCID: PMC1312384 Modulation of renal-specific oxidoreductase/myo-inositol oxygenase by high-glucose ambience Baibaswata Nayak, Ping Xie, Shigeru Akagi, Qiwei Yang, Lin Sun, Jun Wada, Arun Thakur, Farhad R. Danesh, Sumant S. Chugh, and Yashpal S. Kanwar PMCID: PMC1312416 Biophysics Locating high-affinity fatty acid-binding sites on albumin by x-ray crystallography and NMR spectroscopy J. R. Simard, P. A. Zunszain, C.-E. Ha, J. S. Yang, N. V. Bhagavan, I. Petitpas, S. Curry, and J. A. Hamilton PMCID: PMC1312385 Polyproline II propensities from GGXGG peptides reveal an anticorrelation with β-sheet scales Zhengshuang Shi, Kang Chen, Zhigang Liu, Angela Ng, W. Clay Bracken, and Neville R. Kallenbach PMCID: PMC1312395 ATP hydrolysis is required to reset the ATP-binding cassette dimer into the resting-state conformation Gang Lu, James M. Westbrooks, Amy L. Davidson, and Jue Chen PMCID: PMC1312379 Cell Biology The multidomain proapoptotic molecules Bax and Bak are directly activated by heat Lisa J. Pagliari, Tomomi Kuwana, Christine Bonzon, Donald D. Newmeyer, Shine Tu, Helen M. Beere, and Douglas R. Green PMCID: PMC1312392 A genome-wide visual screen reveals a role for sphingolipids and ergosterol in cell surface delivery in yeast Tomasz J. Proszynski, Robin W. Klemm, Maike Gravert, Peggy P. Hsu, Yvonne Gloor, Jan Wagner, Karol Kozak, Hannes Grabner, Karen Walzer, Michel Bagnat, Kai Simons, and Christiane Walch-Solimena PMCID: PMC1312417 Oxidizing potential of endosomes and lysosomes limits intracellular cleavage of disulfide-based antibody–drug conjugates Cary D. Austin, Xiaohui Wen, Lewis Gazzard, Christopher Nelson, Richard H. Scheller, and Suzie J. Scales PMCID: PMC1298180 From the Cover:
Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production Aleksandra Trifunovic, Anna Hansson, Anna Wredenberg, Anja T. Rovio, Eric Dufour, Ivan Khvorostov, Johannes N. Spelbrink, Rolf Wibom, Howard T. Jacobs, and Nils-Göran Larsson PMCID: PMC1312403 Comparison of the protein-unfolding pathways between mitochondrial protein import and atomic-force microscopy measurements Takehiro Sato, Masatoshi Esaki, Julio M. Fernandez, and Toshiya Endo PMCID: PMC1312372 Unbiased selection of localization elements reveals cis-acting determinants of mRNA bud localization in Saccharomyces cerevisiae Ashwini Jambhekar, Kimberly McDermott, Katherine Sorber, Kelly A. Shepard, Ronald D. Vale, Peter A. Takizawa, and Joseph L. DeRisi PMCID: PMC1298916 Developmental Biology Fat storage in adipocytes requires inactivation of leptin's paracrine activity: Implications for treatment of human obesity May-yun Wang, Lelio Orci, Mariella Ravazzola, and Roger H. Unger PMCID: PMC1312408 Drosophila microRNAs exhibit diverse spatial expression patterns during embryonic development A. Aziz Aboobaker, Pavel Tomancak, Nipam Patel, Gerald M. Rubin, and Eric C. Lai PMCID: PMC1306796 BMP signaling stimulates cellular differentiation at multiple steps during cartilage development Tatsuya Kobayashi, Karen M. Lyons, Andrew P. McMahon, and Henry M. Kronenberg PMCID: PMC1312369 Identification of a hyaluronidase, Hyal5, involved in penetration of mouse sperm through cumulus mass Ekyune Kim, Daichi Baba, Masanori Kimura, Misuzu Yamashita, Shin-ichi Kashiwabara, and Tadashi Baba PMCID: PMC1312394 A WW domain protein TAZ is a critical coactivator for TBX5, a transcription factor implicated in Holt–Oram syndrome Masao Murakami, Masayo Nakagawa, Eric N. Olson, and Osamu Nakagawa PMCID: PMC1312418 Ecology Dynamic patterns of adaptive radiation Sergey Gavrilets and Aaron Vose PMCID: PMC1312382 Scales of benthic–pelagic coupling and the intensity of species interactions: From recruitment limitation to top-down control Sergio A. Navarrete, Evie A. Wieters, Bernardo R. Broitman, and Juan Carlos Castilla PMCID: PMC1312419 Forest response to elevated CO2 is conserved across a broad range of productivity Richard J. Norby, Evan H. DeLucia, Birgit Gielen, Carlo Calfapietra, Christian P. Giardina, John S. King, Joanne Ledford, Heather R. McCarthy, David J. P. Moore, Reinhart Ceulemans, Paolo De Angelis, Adrien C. Finzi, David F. Karnosky, Mark E. Kubiske, Martin Lukac, Kurt S. Pregitzer, Giuseppe E. Scarascia-Mugnozza, William H. Schlesinger, and Ram Oren PMCID: PMC1312431 Evolution Evolution of bird eggs in the absence of cuckoo parasitism David C. Lahti PMCID: PMC1312405 Phenogenetic drift in evolution: The changing genetic basis of vertebrate teeth Kazuhiko Kawasaki, Tohru Suzuki, and Kenneth M. Weiss PMCID: PMC1312428 Genetics Premature condensation induces breaks at the interface of early and late replicating chromosome bands bearing common fragile sites Eliane El Achkar, Michelle Gerbault-Seureau, Martine Muleris, Bernard Dutrillaux, and Michelle Debatisse PMCID: PMC1312387 The SET domain protein Metnase mediates foreign DNA integration and links integration to nonhomologous end-joining repair Suk-Hee Lee, Masahiko Oshige, Stephen T. Durant, Kanwaldeep Kaur Rasila, Elizabeth A. Williamson, Heather Ramsey, Lori Kwan, Jac A. Nickoloff, and Robert Hromas PMCID: PMC1312370 MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation Nadia Felli, Laura Fontana, Elvira Pelosi, Rosanna Botta, Desirée Bonci, Francesco Facchiano, Francesca Liuzzi, Valentina Lulli, Ornella Morsilli, Simona Santoro, Mauro Valtieri, George Adrian Calin, Chang-Gong Liu, Antonio Sorrentino, Carlo M. Croce, and Cesare Peschle PMCID: PMC1312381 Occupancy of the Drosophila hsp70 promoter by a subset of basal transcription factors diminishes upon transcriptional activation Lyubov A. Lebedeva, Elena N. Nabirochkina, Mariya M. Kurshakova, Flavie Robert, Aleksey N. Krasnov, Mihail B. Evgen'ev, James T. Kadonaga, Sofia G. Georgieva, and Làszlò Tora PMCID: PMC1306797 Immunology Peripheral B cells latently infected with Epstein–Barr virus display molecular hallmarks of classical antigen-selected memory B cells Tatyana A. Souza, B. David Stollar, John L. Sullivan, Katherine Luzuriaga, and David A. Thorley-Lawson PMCID: PMC1306799 Preligand assembly domain-mediated ligand-independent association between TRAIL receptor 4 (TR4) and TR2 regulates TRAIL-induced apoptosis Lauren Clancy, Karen Mruk, Kristina Archer, Melissa Woelfel, Juthathip Mongkolsapaya, Gavin Screaton, Michael J. Lenardo, and Francis Ka-Ming Chan PMCID: PMC1312398 Developmental checkpoints of the basophil/mast cell lineages in adult murine hematopoiesis Yojiro Arinobu, Hiromi Iwasaki, Michael F. Gurish, Shin-ichi Mizuno, Hirokazu Shigematsu, Hidetoshi Ozawa, Daniel G. Tenen, K. Frank Austen, and Koichi Akashi PMCID: PMC1312421 Medical Sciences Chemokines direct endothelial progenitors into tumor neovessels Herbert Spring, Thomas Schüler, Bernd Arnold, Günter J. Hämmerling, and Ruth Ganss PMCID: PMC1312396 Regulation of muscle growth by multiple ligands signaling through activin type II receptors Se-Jin Lee, Lori A. Reed, Monique V. Davies, Stefan Girgenrath, Mary E. P. Goad, Kathy N. Tomkinson, Jill F. Wright, Christopher Barker, Gregory Ehrmantraut, James Holmstrom, Betty Trowell, Barry Gertz, Man-Shiow Jiang, Suzanne M. Sebald, Martin Matzuk, En Li, Li-fang Liang, Edwin Quattlebaum, Ronald L. Stotish, and Neil M. Wolfman PMCID: PMC1306793 Somatic events modify hypertrophic cardiomyopathy pathology and link hypertrophy to arrhythmia Cordula M. Wolf, Ivan P. G. Moskowitz, Scott Arno, Dorothy M. Branco, Christopher Semsarian, Scott A. Bernstein, Michael Peterson, Michael Maida, Gregory E. Morley, Glenn Fishman, Charles I. Berul, Christine E. Seidman, and J. G. Seidman PMCID: PMC1307513 Reduced Paneth cell α-defensins in ileal Crohn's disease Jan Wehkamp, Nita H. Salzman, Edith Porter, Sabine Nuding, Michael Weichenthal, Robert E. Petras, Bo Shen, Elke Schaeffeler, Matthias Schwab, Rose Linzmeier, Ryan W. Feathers, Hiutung Chu, Heriberto Lima, Jr., Klaus Fellermann, Tomas Ganz, Eduard F. Stange, and Charles L. Bevins PMCID: PMC1306791 Protease nexin-2/amyloid β-protein precursor limits cerebral thrombosis Feng Xu, Judianne Davis, Jianting Miao, Mary Lou Previti, Galina Romanov, Kelly Ziegler, and William E. Van Nostrand PMCID: PMC1312400 Microbiology Quantification of the effect of vaccination on transmission of avian influenza (H7N7) in chickens J. A. van der Goot, G. Koch, M. C. M. de Jong, and M. van Boven PMCID: PMC1312373 The genome of Salinibacter ruber: Convergence and gene exchange among hyperhalophilic bacteria and archaea E. F. Mongodin, K. E. Nelson, S. Daugherty, R. T. DeBoy, J. Wister, H. Khouri, J. Weidman, D. A. Walsh, R. T. Papke, G. Sanchez Perez, A. K. Sharma, C. L. Nesbø, D. MacLeod, E. Bapteste, W. F. Doolittle, R. L. Charlebois, B. Legault, and F. Rodriguez-Valera PMCID: PMC1312414 Human cytomegalovirus virion protein complex required for epithelial and endothelial cell tropism Dai Wang and Thomas Shenk PMCID: PMC1312424 Down-regulation of the retinoblastoma tumor suppressor by the hepatitis C virus NS5B RNA-dependent RNA polymerase Tsubasa Munakata, Mitsuyasu Nakamura, Yuqiong Liang, Kui Li, and Stanley M. Lemon PMCID: PMC1307512 Neuroscience Genetic dissection of theta rhythm heterogeneity in mice Jonghan Shin, Daesoo Kim, Riccardo Bianchi, Robert K. S. Wong, and Hee-Sup Shin PMCID: PMC1306792 Human stem/progenitor cells from bone marrow promote neurogenesis of endogenous neural stem cells in the hippocampus of mice James R. Munoz, Brooke R. Stoutenger, Andrew P. Robinson, Jeffrey L. Spees, and Darwin J. Prockop PMCID: PMC1312406 Identification of an Nav1.1 sodium channel (SCN1A) loss-of-function mutation associated with familial simple febrile seizures Massimo Mantegazza, Antonio Gambardella, Raffaella Rusconi, Emanuele Schiavon, Ferdinanda Annesi, Rita Restano Cassulini, Angelo Labate, Sara Carrideo, Rosanna Chifari, Maria Paola Canevini, Raffaele Canger, Silvana Franceschetti, Grazia Annesi, Enzo Wanke, and Aldo Quattrone PMCID: PMC1312393 Expression pattern of the transcription factor Olig2 in response to brain injuries: Implications for neuronal repair Annalisa Buffo, Milan R. Vosko, Dilek Ertürk, Gerhard F. Hamann, Mathias Jucker, David Rowitch, and Magdalena Götz PMCID: PMC1312388 FGF-2 promotes neurogenesis and neuroprotection and prolongs survival in a transgenic mouse model of Huntington's disease Kunlin Jin, Michelle LaFevre-Bernt, Yunjuan Sun, Sylvia Chen, Juliette Gafni, Danielle Crippen, Anna Logvinova, Christopher A. Ross, David A. Greenberg, and Lisa M. Ellerby PMCID: PMC1312383 From the Cover:
Pharmacological modulation of pain-related brain activity during normal and central sensitization states in humans G. D. Iannetti, L. Zambreanu, R. G. Wise, T. J. Buchanan, J. P. Huggins, T. S. Smart, W. Vennart, and I. Tracey PMCID: PMC1306794 Tissue plasminogen activator and plasminogen mediate stress-induced decline of neuronal and cognitive functions in the mouse hippocampus Robert Pawlak, B. S. Shankaranarayana Rao, Jerry P. Melchor, Sumantra Chattarji, Bruce McEwen, and Sidney Strickland PMCID: PMC1312427 Molecular tuning of fast gating in pentameric ligand-gated ion channels Thomas Grutter, Lia Prado de Carvalho, Virginie Dufresne, Antoine Taly, Stuart J. Edelstein, and Jean-Pierre Changeux PMCID: PMC1312410 Physiology Short-amplitude high-frequency wing strokes determine the aerodynamics of honeybee flight Douglas L. Altshuler, William B. Dickson, Jason T. Vance, Stephen P. Roberts, and Michael H. Dickinson PMCID: PMC1312389 Changes in the chemical and dynamic properties of cardiac troponin T cause discrete cardiomyopathies in transgenic mice Briar R. Ertz-Berger, Huamei He, Candice Dowell, Stephen M. Factor, Todd E. Haim, Sara Nunez, Steven D. Schwartz, Joanne S. Ingwall, and Jil C. Tardiff PMCID: PMC1298915 Plant Biology A UV-B-specific signaling component orchestrates plant UV protection Bobby A. Brown, Catherine Cloix, Guang Huai Jiang, Eirini Kaiserli, Pawel Herzyk, Daniel J. Kliebenstein, and Gareth I. Jenkins PMCID: PMC1312397 Population Biology From the Cover:
Sex ratio bias, male aggression, and population collapse in lizards Jean-François Le Galliard, Patrick S. Fitze, Régis Ferrière, and Jean Clobert PMCID: PMC1312374 Psychology Off-line learning of motor skill memory: A double dissociation of goal and movement Daniel A. Cohen, Alvaro Pascual-Leone, Daniel Z. Press, and Edwin M. Robertson PMCID: PMC1312380 Correction Proc Natl Acad Sci U S A. 2005 December 13; 102(50): 18242. doi: 10.1073/pnas.0509529102.PMCID: PMC1312432 Corrects: S. Ortiz-García, et al. Absence of detectable transgenes in local landraces of maize in Oaxaca, Mexico (2003–2004). Proc Natl Acad Sci U S A. 2005 August 30; 102(35): 12338–12343. |
