NIH Clinical Research Studies Listed By Institute of the Principal Investigator

National Heart, Lung and Blood Institute (NHLBI)

133 Protocols (84 Active Accrual of new subjects, 49 Follow-up of previously enrolled subjects)


Active Follow-up, Protocols NOT Recruiting New Patients 
* 05-H-0088:
Evaluation of the Mechanism of NO Formation and Pharmacokinetics of Systemic Nitrite Infusion

* 05-H-0016:
Therapeutic Application of Intravascular Nitrite for Sickle Cell Disease

* 04-H-0213:
Cytokine Gene Polymorphisms in Bone Marrow Failure

* 04-H-0198:
A Pilot Trial of an Accelerated Immunization Schedule with ALVAC-pp65 (vCP260) for Inducing CMV-Specific Immunity in Stem Cell Allotransplant Donors and Healthy Volunteers

* 04-H-0179:
Peripheral Blood Hematopoietic Progenitor Cell Mobilization Using Granulocyte Colony Stimulating Factor (G-CSF) Combined With AMD3100 in Healthy Volunteers

* 04-H-0143:
Modulation of Vascular Endothelial Growth Factor (VEGF) Using an Engineered Zinc-Finger Transcription Factor to Treat Lower Limb Intermittent Claudication

* 04-H-0112:
Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation Followed by T Cell Add-Back for Hematological Malignancies - Effect of Peritransplant Cyclosporine on Chimerism

* 04-H-0090:
A Pilot Study of the Safety and Efficacy of Imatinib in Reducing Monocytosis or Leukocytosis in Patients with Chronic Myelomonocytic Leukemia and Atypical Chronic Myelogenous Leukemia, Respectively

* 03-H-0312:
Dietary Nitrate/Nitrite as Sources of Bioactive Nitric Oxide in Patients with Coronary Artery Disease

* 03-H-0282:
Characterization of Cardiac Function in Patients with Hereditary Hemochromatosis Who Are New York Heart Association Functional Class I

* 03-H-0219:
A Genome-Wide Scan for Quantitative Trait Loci of Hematocrit - A Framingham Study

* 03-H-0201:
Cytokine Gene Polymorphisms in Allotransplant Donors

* 03-H-0193:
A Randomized Trial of a Novel Immunosuppressive Combination of ATG, CsA and Sirolimus (Rapamune) vs a Slow Taper Cyclosporine Regimen in Subjects with Severe Aplastic Anemia

* 03-H-0192:
Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation Followed by T Cell Add-back for Hematological Malignancies - Effect of Irradiated Donor Lymphocytes on Chimerism

* 02-H-0265:
Identification of Genes Expressed in Atherosclerotic Plaques

* 02-H-0111:
Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation Followed by T Cell Add-Back for Hematological Malignancies - Role of Preparative Regimen and T Cell Dose in Graft Rejection and GVHD

* 01-H-0223:
Inhaled Nitric Oxide and Transfusion Therapy for Patients with Sickle Cell Anemia and Secondary Pulmonary Hypertension

* 01-H-0162:
Ex Vivo Selective Depletion of Alloreactive Donor T-Lymphocytes Utilizing RFT5-SMPT-dgA, a Specific Anti-Interleukin-2 Receptor Immunotoxin: Reducing GVHD Risk Associated with HLA-Matched, Nonmyeloablative, Peripheral Blood Stem Cell Transplantation for

* 01-H-0031:
National Heart, Lung, and Blood Institute Data Distribution

* 00-H-0169:
A Phase II Study of Antithymocyte Globulin (ATG) and Cyclosporine to Treat the Cytopenia of Myelodysplastic Syndrome (MDS)

* 00-H-0032:
Treatment of Severe Aplastic Anemia with Combined Immunosuppression: Antithymocyte Globulin (ATG) and Cyclosporine A (CSA), and Mycophenolate Mofetil (MMF)

* 99-H-0064:
Exploratory Study of Non-Myeloablative Allogeneic Stem Cell Transplantation and Donor Lymphocyte Infusions for Metastatic Neoplasms Refractory to Standard Therapy

* 99-H-0046:
Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation Followed by T-Cell Add-Back for Hematological Malignancies - Role of Cyclosporine

* 97-H-0202:
Low Intensity Preparative Regimen Followed by HLA-Matched, Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Hematologic Malignancies in Older Adults

* 97-H-0130:
Collection of Blood and Bone Marrow from Normal Volunteers and Patients for Research Purposes

* 97-H-0117:
A Randomized Trial of Antithymocyte Globulin and Cyclosporine versus Cyclophosphamide and Cyclosporine in the Treatment of Severe Aplastic Anemia

* 97-H-0099:
HLA-Matched Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation Followed by T Cell Add-Back for Hematological Malignancies

* 95-H-0167:
Effect of Hypoxia and Smoking on Oxidation of Proteins and Nucleic Acids in Human Volunteers

* 94-H-0033:
Retroviral Mediated Gene Transfer of the Fanconi Anemia Complementation Group C Gene to Hematopoietic Progenitors of Group C Patients

* 86-H-0088:
Lymphocytapheresis of Patients with Pancytopenia

* 85-H-0105:
Cardiovascular Evaluation of Homozygous Familial Hypercholesterolemia

* 85-H-0087:
Clinical Course of Patients with Transfusional Hemochromatosis on Deferoxamine

* 84-H-0029:
Effect of Hydroxyurea on Fetal Hemoglobin Synthesis in Patients with Sickle Cell Anemia

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