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Volume 33(1);  2005
Articles
Contextual interactions determine whether the Drosophila homeodomain protein, Vnd, acts as a repressor or activator
Zhongxin Yu, Li-Jyun Syu, and Dervla M. Mellerick
Nucleic Acids Res. 2005; 33(1): 1–12. Published online 2005 January 7. doi: 10.1093/nar/gki140.
PMCID: PMC546129
Regulation of androgen receptor and histone deacetylase 1 by Mdm2-mediated ubiquitylation
Luke Gaughan, Ian R. Logan, David E. Neal, and Craig N. Robson
Nucleic Acids Res. 2005; 33(1): 13–26. Published online 2005 January 7. doi: 10.1093/nar/gki141.
PMCID: PMC546130
Synthesis, cellular uptake and HIV-1 Tat-dependent trans-activation inhibition activity of oligonucleotide analogues disulphide-conjugated to cell-penetrating peptides
John J. Turner, Andrey A. Arzumanov, and Michael J. Gait
Nucleic Acids Res. 2005; 33(1): 27–42. Published online 2005 January 7. doi: 10.1093/nar/gki142.
PMCID: PMC546131
New insights into DNA triplexes: residual twist and radial difference as measures of base triplet non-isomorphism and their implication to sequence-dependent non-uniform DNA triplex
R. Thenmalarchelvi and N. Yathindra
Nucleic Acids Res. 2005; 33(1): 43–55. Published online 2005 January 18. doi: 10.1093/nar/gki143.
PMCID: PMC546132
Multi-class cancer classification by total principal component regression (TPCR) using microarray gene expression data
Yongxi Tan, Leming Shi, Weida Tong, and Charles Wang
Nucleic Acids Res. 2005; 33(1): 56–65. Published online 2005 January 7. doi: 10.1093/nar/gki144.
PMCID: PMC546133
DNA-binding properties of ARID family proteins
Antonia Patsialou, Deborah Wilsker, and Elizabeth Moran
Nucleic Acids Res. 2005; 33(1): 66–80. Published online 2005 January 7. doi: 10.1093/nar/gki145.
PMCID: PMC546134
Kinetics of tetramolecular quadruplexes
Jean-Louis Mergny, Anne De Cian, Amar Ghelab, Barbara Saccà, and Laurent Lacroix
Nucleic Acids Res. 2005; 33(1): 81–94. Published online 2005 January 7. doi: 10.1093/nar/gki148.
PMCID: PMC546136
Significant expansion of exon-bordering protein domains during animal proteome evolution
Mingyi Liu, Heiko Walch, Shaoping Wu, and Andrei Grigoriev
Nucleic Acids Res. 2005; 33(1): 95–105. Published online 2005 January 7. doi: 10.1093/nar/gki152.
PMCID: PMC546140
Effects of camptothecin on double-strand break repair by non-homologous end-joining in DNA mismatch repair-deficient human colorectal cancer cell lines
Sandrine Jacob, Catherine Miquel, Alain Sarasin, and Françoise Praz
Nucleic Acids Res. 2005; 33(1): 106–113. Published online 2005 January 7. doi: 10.1093/nar/gki154.
PMCID: PMC546142
Translation of stable hepadnaviral mRNA cleavage fragments induced by the action of phosphorothioate-modified antisense oligodeoxynucleotides
Peter Hasselblatt, Birgit Hockenjos, Christian Thoma, Hubert E. Blum, and Wolf-Bernhard Offensperger
Nucleic Acids Res. 2005; 33(1): 114–125. Published online 2005 January 7. doi: 10.1093/nar/gki155.
PMCID: PMC546143
A precise DNA bend angle is essential for the function of the phage [var phi]29 transcriptional regulator
Laura Pérez-Lago, Margarita Salas, and Ana Camacho
Nucleic Acids Res. 2005; 33(1): 126–134. Published online 2005 January 7. doi: 10.1093/nar/gki146.
PMCID: PMC546135
Isolation and characterization of a thermostable RNA ligase 1 from a Thermus scotoductus bacteriophage TS2126 with good single-stranded DNA ligation properties
Thorarinn Blondal, Audur Thorisdottir, Unnur Unnsteinsdottir, Sigridur Hjorleifsdottir, Arnthor Ævarsson, Sveinn Ernstsson, Olafur H. Fridjonsson, Sigurlaug Skirnisdottir, Jon Oskar Wheat, Anna Gudny Hermannsdottir, Snorri Th. Sigurdsson, Gudmundur O. Hreggvidsson, Albert Vernon Smith, and Jakob K. Kristjansson
Nucleic Acids Res. 2005; 33(1): 135–142. Published online 2005 January 7. doi: 10.1093/nar/gki149.
PMCID: PMC546137
Condensation of oligonucleotides assembled into nicked and gapped duplexes: potential structures for oligonucleotide delivery
Tumpa Sarkar, Christine C. Conwell, Lilia C. Harvey, Catherine T. Santai, and Nicholas V. Hud
Nucleic Acids Res. 2005; 33(1): 143–151. Published online 2005 January 7. doi: 10.1093/nar/gki156.
PMCID: PMC546144
Differential activation of DNA-PK based on DNA strand orientation and sequence bias
Katherine S. Pawelczak, Brooke J. Andrews, and John J. Turchi
Nucleic Acids Res. 2005; 33(1): 152–161. Published online 2005 January 7. doi: 10.1093/nar/gki157.
PMCID: PMC546145
MAP2: multiple alignment of syntenic genomic sequences
Liang Ye and Xiaoqiu Huang
Nucleic Acids Res. 2005; 33(1): 162–170. Published online 2005 January 7. doi: 10.1093/nar/gki159.
PMCID: PMC546147
Functional roles of carboxylate residues comprising the DNA polymerase active site triad of Ty3 reverse transcriptase
Arkadiusz Bibillo, Daniela Lener, George J. Klarmann, and Stuart F. J. Le Grice
Nucleic Acids Res. 2005; 33(1): 171–181. Published online 2005 January 12. doi: 10.1093/nar/gki150.
PMCID: PMC546138
Site-specific labeling of the ribosome for single-molecule spectroscopy
Magdalena Dorywalska, Scott C. Blanchard, Ruben L. Gonzalez, Jr, Harold D. Kim, Steven Chu, and Joseph D. Puglisi
Nucleic Acids Res. 2005; 33(1): 182–189. Published online 2005 January 12. doi: 10.1093/nar/gki151.
PMCID: PMC546139
The RNA ligands for mouse proline-rich RNA-binding protein (mouse Prrp) contain two consensus sequences in separate loop structure
Tamaki Hori, Yusuke Taguchi, Seiichi Uesugi, and Yasuyuki Kurihara
Nucleic Acids Res. 2005; 33(1): 190–200. Published online 2005 January 12. doi: 10.1093/nar/gki153.
PMCID: PMC546141
A large-scale analysis of mRNA polyadenylation of human and mouse genes
Bin Tian, Jun Hu, Haibo Zhang, and Carol S. Lutz
Nucleic Acids Res. 2005; 33(1): 201–212. Published online 2005 January 12. doi: 10.1093/nar/gki158.
PMCID: PMC546146
i-motif solution structure and dynamics of the d(AACCCC) and d(CCCCAA) tetrahymena telomeric repeats
Narcisse Esmaili and Jean Louis Leroy
Nucleic Acids Res. 2005; 33(1): 213–224. Published online 2005 January 12. doi: 10.1093/nar/gki160.
PMCID: PMC546148
GM-CSF promoter chromatin remodelling and gene transcription display distinct signal and transcription factor requirements
Kate H. Brettingham-Moore, Sudha Rao, Torsten Juelich, M. Frances Shannon, and Adele F. Holloway
Nucleic Acids Res. 2005; 33(1): 225–234. Published online 2005 January 12. doi: 10.1093/nar/gki161.
PMCID: PMC546149
Inhibition of HIV-1 gene expression by retroviral vector-mediated small-guide RNAs that direct specific RNA cleavage by tRNase ZL
Yuichiro Habu, Naoko Miyano-Kurosaki, Michiko Kitano, Yumihiko Endo, Masakazu Yukita, Shigeru Ohira, Hiroaki Takaku, Masayuki Nashimoto, and Hiroshi Takaku
Nucleic Acids Res. 2005; 33(1): 235–243. Published online 2005 January 12. doi: 10.1093/nar/gki164.
PMCID: PMC546152
Accuracy of structure-derived properties in simple comparative models of protein structures
Suvobrata Chakravarty, Lei Wang, and Roberto Sanchez
Nucleic Acids Res. 2005; 33(1): 244–259. Published online 2005 January 12. doi: 10.1093/nar/gki162.
PMCID: PMC546150
Processing of a complex multiply damaged DNA site by human cell extracts and purified repair proteins
Grégory Eot-Houllier, Séverine Eon-Marchais, Didier Gasparutto, and Evelyne Sage
Nucleic Acids Res. 2005; 33(1): 260–271. Published online 2005 January 12. doi: 10.1093/nar/gki165.
PMCID: PMC546153
Inferring combinatorial regulation of transcription in silico
Nils Blüthgen, Szymon M. Kiełbasa, and Hanspeter Herzel
Nucleic Acids Res. 2005; 33(1): 272–279. Published online 2005 January 12. doi: 10.1093/nar/gki167.
PMCID: PMC546154
The accumulation of MMS-induced single strand breaks in G1 phase is recombinogenic in DNA polymerase β defective mammalian cells
Barbara Pascucci, Maria Teresa Russo, Marco Crescenzi, Margherita Bignami, and Eugenia Dogliotti
Nucleic Acids Res. 2005; 33(1): 280–288. Published online 2005 January 12. doi: 10.1093/nar/gki168.
PMCID: PMC546155
Deficiency in 3′-phosphoglycolate processing in human cells with a hereditary mutation in tyrosyl-DNA phosphodiesterase (TDP1)
Tong Zhou, Jae Wan Lee, Haritha Tatavarthi, James R. Lupski, Kristoffer Valerie, and Lawrence F. Povirk
Nucleic Acids Res. 2005; 33(1): 289–297. Published online 2005 January 12. doi: 10.1093/nar/gki170.
PMCID: PMC546157
APE1 overexpression in XRCC1-deficient cells complements the defective repair of oxidative single strand breaks but increases genomic instability
Marguerite Sossou, Claudia Flohr-Beckhaus, Ina Schulz, Fayza Daboussi, Bernd Epe, and J. Pablo Radicella
Nucleic Acids Res. 2005; 33(1): 298–306. Published online 2005 January 12. doi: 10.1093/nar/gki173.
PMCID: PMC546158
Probing a rate-limiting step by mutational perturbation of AdoMet binding in the HhaI methyltransferase
Eglė Merkienė and Saulius Klimašauskas
Nucleic Acids Res. 2005; 33(1): 307–315. Published online 2005 January 13. doi: 10.1093/nar/gki175.
PMCID: PMC546160
Functional domains of the Xenopus replication licensing factor Cdt1
Andrew Ferenbach, Anatoliy Li, Marta Brito-Martins, and J. Julian Blow
Nucleic Acids Res. 2005; 33(1): 316–324. Published online 2005 January 13. doi: 10.1093/nar/gki176.
PMCID: PMC546161
The histone deacetylase inhibitor trichostatin A alters the pattern of DNA replication origin activity in human cells
Michael G. Kemp, Maloy Ghosh, Guoqi Liu, and Michael Leffak
Nucleic Acids Res. 2005; 33(1): 325–336. Published online 2005 January 13. doi: 10.1093/nar/gki177.
PMCID: PMC546162
Multiple promoters are a common feature of mitochondrial genes in Arabidopsis
Kristina Kühn, Andreas Weihe, and Thomas Börner
Nucleic Acids Res. 2005; 33(1): 337–346. Published online 2005 January 13. doi: 10.1093/nar/gki179.
PMCID: PMC546163
RDE-2 interacts with MUT-7 to mediate RNA interference in Caenorhabditis elegans
Bastiaan B. J. Tops, Hiroaki Tabara, Titia Sijen, Femke Simmer, Craig C. Mello, Ronald H. A. Plasterk, and René F. Ketting
Nucleic Acids Res. 2005; 33(1): 347–355. Published online 2005 January 13. doi: 10.1093/nar/gki183.
PMCID: PMC546165
The BRCT domain of mammalian Rev1 is involved in regulating DNA translesion synthesis
Jacob G. Jansen, Anastasia Tsaalbi-Shtylik, Petra Langerak, Fabienne Calléja, Caro M. Meijers, Heinz Jacobs, and Niels de Wind
Nucleic Acids Res. 2005; 33(1): 356–365. Published online 2005 January 13. doi: 10.1093/nar/gki189.
PMCID: PMC546167
Comparative study of sequence-dependent hybridization kinetics in solution and on microspheres
Michael M. A. Sekar, Will Bloch, and Pamela M. St John
Nucleic Acids Res. 2005; 33(1): 366–375. Published online 2005 January 14. doi: 10.1093/nar/gki163.
PMCID: PMC546151
Serum-deprivation stimulates cap-binding by PARN at the expense of eIF4E, consistent with the observed decrease in mRNA stability
Ruth Seal, Richard Temperley, Jeffrey Wilusz, Robert N. Lightowlers, and Zofia M. A. Chrzanowska-Lightowlers
Nucleic Acids Res. 2005; 33(1): 376–387. Published online 2005 January 14. doi: 10.1093/nar/gki169.
PMCID: PMC546156
Plant tRNA ligases are multifunctional enzymes that have diverged in sequence and substrate specificity from RNA ligases of other phylogenetic origins
Markus Englert and Hildburg Beier
Nucleic Acids Res. 2005; 33(1): 388–399. Published online 2005 January 14. doi: 10.1093/nar/gki174.
PMCID: PMC546159
Destabilization of tetranucleotide repeats in Haemophilus influenzae mutants lacking RnaseHI or the Klenow domain of PolI
Christopher D. Bayliss, Wendy A. Sweetman, and E. Richard Moxon
Nucleic Acids Res. 2005; 33(1): 400–408. Published online 2005 January 14. doi: 10.1093/nar/gki180.
PMCID: PMC546164
Conserved transcription factor binding sites of cancer markers derived from primary lung adenocarcinoma microarrays
Yee Leng Yap, Maria P. Wong, Xue Wu Zhang, David Hernandez, Robin Gras, David K. Smith, and Antoine Danchin
Nucleic Acids Res. 2005; 33(1): 409–421. Published online 2005 January 14. doi: 10.1093/nar/gki188.
PMCID: PMC546166
Translocation of XRCC1 and DNA ligase IIIα from centrosomes to chromosomes in response to DNA damage in mitotic human cells
Satoshi Okano, Li Lan, Alan E. Tomkinson, and Akira Yasui
Nucleic Acids Res. 2005; 33(1): 422–429. Published online 2005 January 14. doi: 10.1093/nar/gki190.
PMCID: PMC546168
Probing the DNA kink structure induced by the hyperthermophilic chromosomal protein Sac7d
Chin-Yu Chen, Tzu-Ping Ko, Ting-Wan Lin, Chia-Cheng Chou, Chun-Jung Chen, and Andrew H.-J. Wang
Nucleic Acids Res. 2005; 33(1): 430–438. Published online 2005 January 14. doi: 10.1093/nar/gki191.
PMCID: PMC546169
Locked nucleic acid (LNA) mediated improvements in siRNA stability and functionality
Joacim Elmén, Håkan Thonberg, Karl Ljungberg, Miriam Frieden, Majken Westergaard, Yunhe Xu, Britta Wahren, Zicai Liang, Henrik Ørum, Troels Koch, and Claes Wahlestedt
Nucleic Acids Res. 2005; 33(1): 439–447. Published online 2005 January 14. doi: 10.1093/nar/gki193.
PMCID: PMC546170
Methods Online
Rapid, solid-phase based automated analysis of chromatin structure and transcription factor occupancy in living eukaryotic cells
Richard Ingram, Hiromi Tagoh, Arthur D. Riggs, and Constanze Bonifer
Nucleic Acids Res. 2005; 33(1): e1. Published online 2005 January 11. doi: 10.1093/nar/gni001.
PMCID: PMC546173
Detection and discovery of RNA modifications using microarrays
Shawna L. Hiley, Jane Jackman, Tomas Babak, Miles Trochesset, Quaid D. Morris, Eric Phizicky, and Timothy R. Hughes
Nucleic Acids Res. 2005; 33(1): e2. Published online 2005 January 7. doi: 10.1093/nar/gni002.
PMCID: PMC546174
ArrayOme: a program for estimating the sizes of microarray-visualized bacterial genomes
Hong-Yu Ou, Rebecca Smith, Sacha Lucchini, Jay Hinton, Roy R. Chaudhuri, Mark Pallen, Michael R. Barer, and Kumar Rajakumar
Nucleic Acids Res. 2005; 33(1): e3. Published online 2005 January 7. doi: 10.1093/nar/gni005.
PMCID: PMC546176
Non-cross-linking gold nanoparticle aggregation as a detection method for single-base substitutions
Kae Sato, Kazuo Hosokawa, and Mizuo Maeda
Nucleic Acids Res. 2005; 33(1): e4. Published online 2005 January 7. doi: 10.1093/nar/gni007.
PMCID: PMC546178
Mapping the B-A conformational transition along plasmid DNA
Karel Nejedlý, Jana Chládková, Michaela Vorlíčková, Iva Hrabcová, and Jaroslav Kypr
Nucleic Acids Res. 2005; 33(1): e5. Published online 2005 January 7. doi: 10.1093/nar/gni008.
PMCID: PMC546179
Detection and characterization of horizontal transfers in prokaryotes using genomic signature
Christine Dufraigne, Bernard Fertil, Sylvain Lespinats, Alain Giron, and Patrick Deschavanne
Nucleic Acids Res. 2005; 33(1): e6. Published online 2005 January 13. doi: 10.1093/nar/gni004.
PMCID: PMC546175
Conditional UAS-targeted repression in Drosophila
Alberto Pascual, Kai-Lian Huang, and Thomas Preat
Nucleic Acids Res. 2005; 33(1): e7. Published online 2005 January 13. doi: 10.1093/nar/gni006.
PMCID: PMC546177
Use of a restriction enzyme-digested PCR product as substrate for helicase assays
Jae-Ho Shin, John N. Reeve, and Zvi Kelman
Nucleic Acids Res. 2005; 33(1): e8. Published online 2005 January 13. doi: 10.1093/nar/gni009.
PMCID: PMC546180
BiSearch: primer-design and search tool for PCR on bisulfite-treated genomes
Gábor E. Tusnády, István Simon, András Váradi, and Tamás Arányi
Nucleic Acids Res. 2005; 33(1): e9. Published online 2005 January 13. doi: 10.1093/nar/gni012.
PMCID: PMC546182
Covalent antibody display—an in vitro antibody-DNA library selection system
Herald Reiersen, Inger Løbersli, Geir Å. Løset, Else Hvattum, Bjørg Simonsen, John E. Stacy, Duncan McGregor, Kevin FitzGerald, Martin Welschof, Ole H. Brekke, and Ole J. Marvik
Nucleic Acids Res. 2005; 33(1): e10. Published online 2005 January 14. doi: 10.1093/nar/gni010.
PMCID: PMC546181
Corrigendum
HOPPSIGEN: a database of human and mouse processed pseudogenes
Khelifi Adel, Durent Laurent, and Mouchiroud Dominique
Nucleic Acids Res. 2005; 33(1): 448. Published online 2005 January 18. doi: 10.1093/nar/gki217.
PMCID: PMC546172
Corrects: Khelifi Adel, et al. HOPPSIGEN: a database of human and mouse processed pseudogenes. Nucleic Acids Res. 2005 January 1; 33(Database Issue): D59–D66.
Erratum
FESD: a Functional Element SNPs Database in human
Hyo Jin Kang, Kyoung Oak Choi, Byung-Dong Kim, Sangsoo Kim, and Young Joo Kim
Nucleic Acids Res. 2005; 33(1): 449. Published online 2005 January 18. doi: 10.1093/nar/gki216.
PMCID: PMC546171
Corrects: Hyo Jin Kang, et al. FESD: a Functional Element SNPs Database in human. Nucleic Acids Res. 2005 January 1; 33(Database Issue): D518–D522.
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