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Volume 36(11);  June 2008
Molecular Biology
Sequence-specific DNA cleavage mediated by bipyridine polyamide conjugates
Philippe Simon, Fabio Cannata, Loïc Perrouault, Ludovic Halby, Jean-Paul Concordet, Alexandre Boutorine, Vladimir Ryabinin, Alexandre Sinyakov, and Carine Giovannangeli
Nucleic Acids Res. 2008 June; 36(11): 3531–3538. Published online 2008 June. doi: 10.1093/nar/gkn231.
PMCID: PMC2441794
Cooperation between EZH2, NSPc1-mediated histone H2A ubiquitination and Dnmt1 in HOX gene silencing
Xudong Wu, Yanhua Gong, Jiping Yue, Boqin Qiang, Jiangang Yuan, and Xiaozhong Peng
Nucleic Acids Res. 2008 June; 36(11): 3590–3599. Published online 2008 June. doi: 10.1093/nar/gkn243.
PMCID: PMC2441805
TRE-dependent transcription activation by JDP2–CHOP10 association
Keren Weidenfeld-Baranboim, Keren Bitton-Worms, and Ami Aronheim
Nucleic Acids Res. 2008 June; 36(11): 3608–3619. Published online 2008 June. doi: 10.1093/nar/gkn268.
PMCID: PMC2441799
Characterization of genome-wide p53-binding sites upon stress response
Leonie Smeenk, Simon J. van Heeringen, Max Koeppel, Marc A. van Driel, Stefanie J. J. Bartels, Robert C. Akkers, Sergei Denissov, Hendrik G. Stunnenberg, and Marion Lohrum
Nucleic Acids Res. 2008 June; 36(11): 3639–3654. Published online 2008 June. doi: 10.1093/nar/gkn232.
PMCID: PMC2441782
Mechanism of high-mobility group protein B enhancement of progesterone receptor sequence-specific DNA binding
Sarah C. Roemer, James Adelman, Mair E. A. Churchill, and Dean P. Edwards
Nucleic Acids Res. 2008 June; 36(11): 3655–3666. Published online 2008 June. doi: 10.1093/nar/gkn249.
PMCID: PMC2441811
LINE-1 methylation status of endogenous DNA double-strand breaks
Wichai Pornthanakasem, Narisorn Kongruttanachok, Chutipa Phuangphairoj, Chotika Suyarnsestakorn, Taweap Sanghangthum, Sornjarod Oonsiri, Wanpen Ponyeam, Thatchawan Thanasupawat, Oranart Matangkasombut, and Apiwat Mutirangura
Nucleic Acids Res. 2008 June; 36(11): 3667–3675. Published online 2008 June. doi: 10.1093/nar/gkn261.
PMCID: PMC2441779
Streptococcus pyogenes pSM19035 requires dynamic assembly of ATP-bound ParA and ParB on parS DNA during plasmid segregation
Florencia Pratto, Aslan Cicek, Wilhelm A. Weihofen, Rudi Lurz, Wolfram Saenger, and Juan C. Alonso
Nucleic Acids Res. 2008 June; 36(11): 3676–3689. Published online 2008 June. doi: 10.1093/nar/gkn170.
PMCID: PMC2441792
The bHLH/Per-Arnt-Sim transcription factor SIM2 regulates muscle transcript myomesin2 via a novel, non-canonical E-box sequence
Susan Woods, Alexandra Farrall, Carl Procko, and Murray L. Whitelaw
Nucleic Acids Res. 2008 June; 36(11): 3716–3727. Published online 2008 June. doi: 10.1093/nar/gkn247.
PMCID: PMC2441813
Recruitment of RNA polymerase III in vivo
Niall S. Kenneth, Lynne Marshall, and Robert J. White
Nucleic Acids Res. 2008 June; 36(11): 3757–3764. Published online 2008 June. doi: 10.1093/nar/gkn272.
PMCID: PMC2441808
Structural polymorphism within a regulatory element of the human KRAS promoter: formation of G4-DNA recognized by nuclear proteins
Susanna Cogoi, Manikandan Paramasivam, Barbara Spolaore, and Luigi E. Xodo
Nucleic Acids Res. 2008 June; 36(11): 3765–3780. Published online 2008 June. doi: 10.1093/nar/gkn120.
PMCID: PMC2441797
Molecular basis for group-specific activation of the virulence regulator PlcR by PapR heptapeptides
L. Bouillaut, S. Perchat, S. Arold, S. Zorrilla, L. Slamti, C. Henry, M. Gohar, N. Declerck, and D. Lereclus
Nucleic Acids Res. 2008 June; 36(11): 3791–3801. Published online 2008 June. doi: 10.1093/nar/gkn149.
PMCID: PMC2441798
In vivo identification of novel STAT5 target genes
Beth Basham, Manjiri Sathe, Jeffrey Grein, Terrill McClanahan, Annalisa D’Andrea, Emma Lees, and Anne Rascle
Nucleic Acids Res. 2008 June; 36(11): 3802–3818. Published online 2008 June. doi: 10.1093/nar/gkn271.
PMCID: PMC2441806
Discovery of novel tumor suppressor p53 response elements using information theory
Ilya G. Lyakhov, Annangarachari Krishnamachari, and Thomas D. Schneider
Nucleic Acids Res. 2008 June; 36(11): 3828–3833. Published online 2008 June. doi: 10.1093/nar/gkn189.
PMCID: PMC2441790
bZIP-Type transcription factors CREB and OASIS bind and stimulate the promoter of the mammalian transcription factor GCMa/Gcm1 in trophoblast cells
Steffen Wolfgang Schubert, Alexandra Abendroth, Karin Kilian, Tina Vogler, Bernhard Mayr, Ina Knerr, and Said Hashemolhosseini
Nucleic Acids Res. 2008 June; 36(11): 3834–3846. Published online 2008 June. doi: 10.1093/nar/gkn306.
PMCID: PMC2441803
A single amino acid change in histone H4 enhances UV survival and DNA repair in yeast
Ronita Nag, Feng Gong, Deirdre Fahy, and Michael J. Smerdon
Nucleic Acids Res. 2008 June; 36(11): 3857–3866. Published online 2008 June. doi: 10.1093/nar/gkn311.
PMCID: PMC2441814
RNA
Ribosomal RNAs are tolerant toward genetic insertions: evolutionary origin of the expansion segments
Takeshi Yokoyama and Tsutomu Suzuki
Nucleic Acids Res. 2008 June; 36(11): 3539–3551. Published online 2008 June. doi: 10.1093/nar/gkn224.
PMCID: PMC2441807
Selection of a novel class of RNA–RNA interaction motifs based on the ligase ribozyme with defined modular architecture
Shoji P. Ohuchi, Yoshiya Ikawa, and Yoshikazu Nakamura
Nucleic Acids Res. 2008 June; 36(11): 3600–3607. Published online 2008 June. doi: 10.1093/nar/gkn206.
PMCID: PMC2441787
Structural Biology
Structural and functional insights into human Tudor-SN, a key component linking RNA interference and editing
Chia-Lung Li, Wei-Zen Yang, Yi-Ping Chen, and Hanna S. Yuan
Nucleic Acids Res. 2008 June; 36(11): 3579–3589. Published online 2008 June. doi: 10.1093/nar/gkn236.
PMCID: PMC2441809
Molecular basis for the lack of enantioselectivity of human 3-phosphoglycerate kinase
C. Gondeau, L. Chaloin, P. Lallemand, B. Roy, C. Périgaud, T. Barman, A. Varga, M. Vas, C. Lionne, and S. T. Arold
Nucleic Acids Res. 2008 June; 36(11): 3620–3629. Published online 2008 June. doi: 10.1093/nar/gkn212.
PMCID: PMC2441801
DNA conformations and their sequence preferences
Daniel Svozil, Jan Kalina, Marek Omelka, and Bohdan Schneider
Nucleic Acids Res. 2008 June; 36(11): 3690–3706. Published online 2008 June. doi: 10.1093/nar/gkn260.
PMCID: PMC2441783
Survey and Summary
Structural and evolutionary classification of Type II restriction enzymes based on theoretical and experimental analyses
Jerzy Orlowski and Janusz M. Bujnicki
Nucleic Acids Res. 2008 June; 36(11): 3552–3569. Published online 2008 June. doi: 10.1093/nar/gkn175.
PMCID: PMC2441816
Genomics
Comprehensive detection of human terminal oligo-pyrimidine (TOP) genes and analysis of their characteristics
Riu Yamashita, Yutaka Suzuki, Nono Takeuchi, Hiroyuki Wakaguri, Takuya Ueda, Sumio Sugano, and Kenta Nakai
Nucleic Acids Res. 2008 June; 36(11): 3707–3715. Published online 2008 June. doi: 10.1093/nar/gkn248.
PMCID: PMC2441802
DNA physical properties determine nucleosome occupancy from yeast to fly
Vincent Miele, Cédric Vaillant, Yves d'Aubenton-Carafa, Claude Thermes, and Thierry Grange
Nucleic Acids Res. 2008 June; 36(11): 3746–3756. Published online 2008 June. doi: 10.1093/nar/gkn262.
PMCID: PMC2441789
Chemistry
Snap-to-it probes: chelate-constrained nucleobase oligomers with enhanced binding specificity
Joel R. Morgan, Robert P. Lyon, Dean Y. Maeda, and John A. Zebala
Nucleic Acids Res. 2008 June; 36(11): 3522–3530. Published online 2008 June. doi: 10.1093/nar/gkn219.
PMCID: PMC2441785
DNA binding of dinuclear iron(II) metallosupramolecular cylinders. DNA unwinding and sequence preference
Jaroslav Malina, Michael J. Hannon, and Viktor Brabec
Nucleic Acids Res. 2008 June; 36(11): 3630–3638. Published online 2008 June. doi: 10.1093/nar/gkn244.
PMCID: PMC2441793
Mechanistic studies on bleomycin-mediated DNA damage: multiple binding modes can result in double-stranded DNA cleavage
Jingyang Chen, Manas K. Ghorai, Grace Kenney, and JoAnne Stubbe
Nucleic Acids Res. 2008 June; 36(11): 3781–3790. Published online 2008 June. doi: 10.1093/nar/gkn302.
PMCID: PMC2441780
Methods Online
High-throughput single-nucleotide structural mapping by capillary automated footprinting analysis
Somdeb Mitra, Inna V. Shcherbakova, Russ B. Altman, Michael Brenowitz, and Alain Laederach
Nucleic Acids Res. 2008 June; 36(11): e63. Published online 2008 June. doi: 10.1093/nar/gkn267.
PMCID: PMC2441812
A simple algorithm for quantifying DNA methylation levels on multiple independent CpG sites in bisulfite genomic sequencing electropherograms
Tatiana I. Leakey, Jerzy Zielinski, Rachel N. Siegfried, Eric R. Siegel, Chun-Yang Fan, and Craig A. Cooney
Nucleic Acids Res. 2008 June; 36(11): e64. Published online 2008 June. doi: 10.1093/nar/gkn210.
PMCID: PMC2441810
Electrochemical detection of low-copy number salivary RNA based on specific signal amplification with a hairpin probe
Fang Wei, Jianghua Wang, Wei Liao, Bernhard G. Zimmermann, David T. Wong, and Chih-Ming Ho
Nucleic Acids Res. 2008 June; 36(11): e65. Published online 2008 June. doi: 10.1093/nar/gkn299.
PMCID: PMC2441804
Predicting failure rate of PCR in large genomes
Reidar Andreson, Tõnu Möls, and Maido Remm
Nucleic Acids Res. 2008 June; 36(11): e66. Published online 2008 June. doi: 10.1093/nar/gkn290.
PMCID: PMC2441781
Regulated gene insertion by steroid-induced ΦC31 integrase
Nynne Sharma, Brian Moldt, Trine Dalsgaard, Thomas G. Jensen, and Jacob Giehm Mikkelsen
Nucleic Acids Res. 2008 June; 36(11): e67. Published online 2008 June. doi: 10.1093/nar/gkn298.
PMCID: PMC2441784
The simple and rapid detection of specific PCR products from bacterial genomes using Zn finger proteins
Yuko Osawa, Kazunori Ikebukuro, Hiroaki Motoki, Takafumi Matsuo, Michio Horiuchi, and Koji Sode
Nucleic Acids Res. 2008 June; 36(11): e68. Published online 2008 June. doi: 10.1093/nar/gkn274.
PMCID: PMC2441800
Computational Biology
3D visualization software to analyze topological outcomes of topoisomerase reactions
I. K. Darcy, R. G. Scharein, and A. Stasiak
Nucleic Acids Res. 2008 June; 36(11): 3515–3521. Published online 2008 June. doi: 10.1093/nar/gkn192.
PMCID: PMC2441796
Spatial effects on the speed and reliability of protein–DNA search
Zeba Wunderlich and Leonid A. Mirny
Nucleic Acids Res. 2008 June; 36(11): 3570–3578. Published online 2008 June. doi: 10.1093/nar/gkn173.
PMCID: PMC2441786
Beyond tissueInfo: functional prediction using tissue expression profile similarity searches
Daniel Aguilar, Lucy Skrabanek, Steven S. Gross, Baldo Oliva, and Fabien Campagne
Nucleic Acids Res. 2008 June; 36(11): 3728–3737. Published online 2008 June. doi: 10.1093/nar/gkn233.
PMCID: PMC2441795
Fundamental differences in the equilibrium considerations for siRNA and antisense oligodeoxynucleotide design
Zhi John Lu and David H. Mathews
Nucleic Acids Res. 2008 June; 36(11): 3738–3745. Published online 2008 June. doi: 10.1093/nar/gkn266.
PMCID: PMC2441788
SCUMBLE: a method for systematic and accurate detection of codon usage bias by maximum likelihood estimation
Morten Kloster and Chao Tang
Nucleic Acids Res. 2008 June; 36(11): 3819–3827. Published online 2008 June. doi: 10.1093/nar/gkn288.
PMCID: PMC2441815
Nucleic Acid Enzymes
Low-fidelity DNA synthesis by human DNA polymerase theta
Mercedes E. Arana, Mineaki Seki, Richard D. Wood, Igor B. Rogozin, and Thomas A. Kunkel
Nucleic Acids Res. 2008 June; 36(11): 3847–3856. Published online 2008 June. doi: 10.1093/nar/gkn310.
PMCID: PMC2441791
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