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Volume 2008;  2008
Clinical Studies
Peroxisome Proliferator-Activated Receptor-equation M1 Is a Potent Target for Prevention and Treatment in Human Prostate and Testicular Cancer
Masahide Matsuyama and Rikio Yoshimura
PPAR Res. 2008; 2008: 249849. Published online 2008 February 19. doi: 10.1155/2008/249849.
PMCID: PMC2248699
Antidiabetic Rosiglitazone Reduces Soluble Intercellular Adhesion Molecule-1 Level in Type 2 Diabetic Patients with Coronary Artery Disease
Guang Wang, Zhe Zhang, Jie Yu, Fuchun Zhang, Liyun He, Jinru Wei, Jieming Mao, and Xian Wang
PPAR Res. 2008; 2008: 548178. Published online 2008 December 18. doi: 10.1155/2008/548178.
PMCID: PMC2605848
Editorials
PPARs/RXRs in Cardiovascular Physiology and Disease
Brian N. Finck, Giulia Chinetti, and Bart Staels
PPAR Res. 2008; 2008: 173780. Published online 2008 March 31. doi: 10.1155/2008/173780.
PMCID: PMC2278368
PPARs in Eye Biology and Disease
Suofu Qin and Roy S. Chuck
PPAR Res. 2008; 2008: 518790. Published online 2008 May 26. doi: 10.1155/2008/518790.
PMCID: PMC2396240
PPARs and RXRs in Male and Female Fertility and Reproduction
P. Froment
PPAR Res. 2008; 2008: 637490. Published online 2008 April 6. doi: 10.1155/2008/637490.
PMCID: PMC2288680
PPARs in Neuroinflammation
Michael K. Racke and Paul D. Drew
PPAR Res. 2008; 2008: 638356. Published online 2008 August 3. doi: 10.1155/2008/638356.
PMCID: PMC2494607
Peroxisome Proliferator-Activated Receptor δ: A Target with a Broad Therapeutic Potential for Drug Discovery
Francine M. Gregoire
PPAR Res. 2008; 2008: 736362. Published online 2009 April 7. doi: 10.1155/2008/736362.
PMCID: PMC2666271
Development of Synthetic Modulators of PPARs: Current Challenges and Future Opportunities
Jane A. Pinaire, Anne Reifel Miller, and Francine M. Gregoire
PPAR Res. 2008; 2008: 786359. Published online 2009 March 23. doi: 10.1155/2008/786359.
PMCID: PMC2659606
Research Articles
Genetic Polymorphisms of Peroxisome Proliferator-Activated Receptors and the Risk of Cardiovascular Morbidity and Mortality in a Community-Based Cohort in Washington County, Maryland
L. Gallicchio, Bindu Kalesan, Han-Yao Huang, Paul Strickland, Sandra C. Hoffman, and Kathy J. Helzlsouer
PPAR Res. 2008; 2008: 276581. Published online 2007 December 4. doi: 10.1155/2008/276581.
PMCID: PMC2233806
Cardiac PPARequation M1 Protein Expression is Constant as Alternate Nuclear Receptors and PGC-1 Coordinately Increase During the Postnatal Metabolic Transition
Norman E. Buroker, Xue-Han Ning, and Michael Portman
PPAR Res. 2008; 2008: 279531. Published online 2008 January 17. doi: 10.1155/2008/279531.
PMCID: PMC2233871
Statins Activate Human PPARα Promoter and Increase PPARα mRNA Expression and Activation in HepG2 Cells
Makoto Seo, Ikuo Inoue, Masaaki Ikeda, Takanari Nakano, Seiichiro Takahashi, Shigehiro Katayama, and Tsugikazu Komoda
PPAR Res. 2008; 2008: 316306. Published online 2008 December 24. doi: 10.1155/2008/316306.
PMCID: PMC2610383
Cryptochrome and Period Proteins Are Regulated by the CLOCK/BMAL1 Gene: Crosstalk between the PPARs/RXRequation M1-Regulated and CLOCK/BMAL1-Regulated Systems
Koh-ichi Nakamura, Ikuo Inoue, Seiichiro Takahashi, Tsugikazu Komoda, and Shigehiro Katayama
PPAR Res. 2008; 2008: 348610. Published online 2008 February 19. doi: 10.1155/2008/348610.
PMCID: PMC2248703
The PPAR-γ Agonist 15-Deoxy-Δ12,14-Prostaglandin J2 Attenuates Microglial Production of IL-12 Family Cytokines: Potential Relevance to Alzheimer's Disease
Jihong Xu, Steven W. Barger, and Paul D. Drew
PPAR Res. 2008; 2008: 349185. Published online 2008 July 2. doi: 10.1155/2008/349185.
PMCID: PMC2442897
Microglia and Astrocyte Activation by Toll-Like Receptor Ligands: Modulation by PPAR-γ Agonists
Catherine Gurley, Jessica Nichols, Shuliang Liu, Nirmal K. Phulwani, Nilufer Esen, and Tammy Kielian
PPAR Res. 2008; 2008: 453120. Published online 2008 June 19. doi: 10.1155/2008/453120.
PMCID: PMC2435222
Cross-Species Differential Plasma Protein Binding of MBX-102/JNJ39659100: A Novel PPAR-γ Agonist
Holly J. Clarke, Francine Gregoire, Fang Ma, Robert Martin, Spring Zhao, and Brian E. Lavan
PPAR Res. 2008; 2008: 465715. Published online 2008 September 14. doi: 10.1155/2008/465715.
PMCID: PMC2535826
Improved Insulin Resistance and Lipid Metabolism by Cinnamon Extract through Activation of Peroxisome Proliferator-Activated Receptors
Xiaoyan Sheng, Yuebo Zhang, Zhenwei Gong, Cheng Huang, and Ying Qin Zang
PPAR Res. 2008; 2008: 581348. Published online 2008 December 11. doi: 10.1155/2008/581348.
PMCID: PMC2602825
Rosiglitazone Suppresses the Growth and Invasiveness of SGC-7901 Gastric Cancer Cells and Angiogenesis In Vitro via PPARγ Dependent and Independent Mechanisms
Qing He, Ruiping Pang, Xin Song, Jie Chen, Huixin Chen, Baili Chen, Pinjin Hu, and Minhu Chen
PPAR Res. 2008; 2008: 649808. Published online 2008 September 15. doi: 10.1155/2008/649808.
PMCID: PMC2542845
Activation of Penile Proadipogenic Peroxisome Proliferator-Activated Receptor γ with an Estrogen: Interaction with Estrogen Receptor Alpha during Postnatal Development
Mahmoud M. Mansour, Hari O. Goyal, Tim D. Braden, John C. Dennis, Dean D. Schwartz, Robert L. Judd, Frank F. Bartol, Elaine S. Coleman, and Edward E. Morrison
PPAR Res. 2008; 2008: 651419. Published online 2008 August 21. doi: 10.1155/2008/651419.
PMCID: PMC2519140
Regulation of Peroxisome Proliferator-Activated Receptors by E6-Associated Protein
Lakshmi Gopinathan, Daniel B. Hannon, Russell W. Smith III, Jeffrey M. Peters, and John P. Vanden Heuvel
PPAR Res. 2008; 2008: 746935. Published online 2008 December 18. doi: 10.1155/2008/746935.
PMCID: PMC2605849
Rosiglitazone Inhibits Adrenocortical Cancer Cell Proliferation by Interfering with the IGF-IR Intracellular Signaling
Giulia Cantini, Adriana Lombardi, Elisabetta Piscitelli, Giada Poli, Elisabetta Ceni, Sara Marchiani, Tonino Ercolino, Andrea Galli, Mario Serio, Massimo Mannelli, and Michaela Luconi
PPAR Res. 2008; 2008: 904041. Published online 2008 July 28. doi: 10.1155/2008/904041.
PMCID: PMC2491299
Review Articles
The Role of PPARs in Cancer
Keisuke Tachibana, Daisuke Yamasaki, Kenji Ishimoto, and Takefumi Doi
PPAR Res. 2008; 2008: 102737. Published online 2008 June 18. doi: 10.1155/2008/102737.
PMCID: PMC2435221
Rat Urinary Bladder Carcinogenesis by Dual-Acting PPARα + γ Agonists
Martin B. Oleksiewicz, Jennifer Southgate, Lars Iversen, and Frederikke L. Egerod
PPAR Res. 2008; 2008: 103167. Published online 2009 January 28. doi: 10.1155/2008/103167.
PMCID: PMC2632771
PPARδ Agonism for the Treatment of Obesity and Associated Disorders: Challenges and Opportunities
Mylène Perreault, David V. Erbe, and James F. Tobin
PPAR Res. 2008; 2008: 125387. Published online 2008 October 29. doi: 10.1155/2008/125387.
PMCID: PMC2577153
Peroxisome Proliferator Activated Receptors and Lipoprotein Metabolism
Sander Kersten
PPAR Res. 2008; 2008: 132960. Published online 2007 November 21. doi: 10.1155/2008/132960.
PMCID: PMC2220040
PPARs Mediate Lipid Signaling in Inflammation and Cancer
Liliane Michalik and Walter Wahli
PPAR Res. 2008; 2008: 134059. Published online 2008 December 21. doi: 10.1155/2008/134059.
PMCID: PMC2606065
PPAR Signaling in Placental Development and Function
Yaacov Barak, Yoel Sadovsky, and Tali Shalom-Barak
PPAR Res. 2008; 2008: 142082. Published online 2007 November 25. doi: 10.1155/2008/142082.
PMCID: PMC2225458
Pathophysiological Roles of PPARγ in Gastrointestinal Epithelial Cells
Brian M. Necela and E. Aubrey Thompson
PPAR Res. 2008; 2008: 148687. Published online 2008 July 6. doi: 10.1155/2008/148687.
PMCID: PMC2443401
Activation and Molecular Targets of Peroxisome Proliferator-Activated Receptor-γ Ligands in Lung Cancer
Raphael A. Nemenoff, Mary Weiser-Evans, and Robert A. Winn
PPAR Res. 2008; 2008: 156875. Published online 2008 May 26. doi: 10.1155/2008/156875.
PMCID: PMC2396386
Clinical Use of PPARγ Ligands in Cancer
Jennifer L. Hatton and Lisa D. Yee
PPAR Res. 2008; 2008: 159415. Published online 2008 December 18. doi: 10.1155/2008/159415.
PMCID: PMC2605846
PPAR-δ in Vascular Pathophysiology
Nanping Wang
PPAR Res. 2008; 2008: 164163. Published online 2009 January 6. doi: 10.1155/2008/164163.
PMCID: PMC2614208
PPARγ Agonists: Potential as Therapeutics for Neovascular Retinopathies
Harrihar A. Pershadsingh and David M. Moore
PPAR Res. 2008; 2008: 164273. Published online 2008 May 26. doi: 10.1155/2008/164273.
PMCID: PMC2396446
Macrophages, PPARs, and Cancer
Jo A. Van Ginderachter, Kiavash Movahedi, Jan Van den Bossche, and Patrick De Baetselier
PPAR Res. 2008; 2008: 169414. Published online 2008 July 3. doi: 10.1155/2008/169414.
PMCID: PMC2443396
Peroxisome Proliferator-Activated Receptor Delta: A Conserved Director of Lipid Homeostasis through Regulation of the Oxidative Capacity of Muscle
Pieter de Lange, Assunta Lombardi, Elena Silvestri, Fernando Goglia, Antonia Lanni, and Maria Moreno
PPAR Res. 2008; 2008: 172676. Published online 2008 September 22. doi: 10.1155/2008/172676.
PMCID: PMC2547483
Role of the Peroxisome Proliferator-Activated Receptors, Adenosine Monophosphate-Activated Kinase, and Adiponectin in the Ovary
Joëlle Dupont, Christine Chabrolle, Christelle Ramé, Lucie Tosca, and Stéphanie Coyral-Castel
PPAR Res. 2008; 2008: 176275. Published online 2007 August 24. doi: 10.1155/2008/176275.
PMCID: PMC2225459
Synergistic Effects of PPARγ Ligands and Retinoids in Cancer Treatment
Masahito Shimizu and Hisataka Moriwaki
PPAR Res. 2008; 2008: 181047. Published online 2008 May 28. doi: 10.1155/2008/181047.
PMCID: PMC2408709
PPARγ in Kidney Physiology and Pathophysiology
Éva Kiss-Tóth and Tamás Rőszer
PPAR Res. 2008; 2008: 183108. Published online 2009 March 10. doi: 10.1155/2008/183108.
PMCID: PMC2654308
Multiple Interactions between Peroxisome Proliferators-Activated Receptors and the Ubiquitin-Proteasome System and Implications for Cancer Pathogenesis
Davide Genini, Giuseppina M. Carbone, and Carlo V. Catapano
PPAR Res. 2008; 2008: 195065. Published online 2008 June 8. doi: 10.1155/2008/195065.
PMCID: PMC2423003
Peroxisome Proliferator-Activated Receptors (PPARs) as Potential Inducers of Antineoplastic Effects in CNS Tumors
Lars Tatenhorst, Eric Hahnen, and Michael T. Heneka
PPAR Res. 2008; 2008: 204514. Published online 2008 August 14. doi: 10.1155/2008/204514.
PMCID: PMC2517124
The Role of PPARγ in Hepatocellular Carcinoma
Ivan Borbath and Yves Horsmans
PPAR Res. 2008; 2008: 209520. Published online 2008 May 26. doi: 10.1155/2008/209520.
PMCID: PMC2396389
To Live or to Die: Prosurvival Activity of PPARγ in Cancers
Y. Lynn Wang and Qi Miao
PPAR Res. 2008; 2008: 209629. Published online 2008 September 8. doi: 10.1155/2008/209629.
PMCID: PMC2532487
PPAR Ligands as Potential Modifiers of Breast Carcinoma Outcomes
Ancha Baranova
PPAR Res. 2008; 2008: 230893. Published online 2008 July 15. doi: 10.1155/2008/230893.
PMCID: PMC2467456
PPAR Gamma: Coordinating Metabolic and Immune Contributions to Female Fertility
Cadence E. Minge, Rebecca L. Robker, and Robert J. Norman
PPAR Res. 2008; 2008: 243791. Published online 2008 January 3. doi: 10.1155/2008/243791.
PMCID: PMC2246065
PPAR Agonists and Cardiovascular Disease in Diabetes
Anna C. Calkin and Merlin C. Thomas
PPAR Res. 2008; 2008: 245410. Published online 2008 January 2. doi: 10.1155/2008/245410.
PMCID: PMC2233765
PPARγ and PPARδ as Modulators of Neoplasia and Cell Fate
Robert I. Glazer, Hongyan Yuan, Zhihui Xie, and Yuzhi Yin
PPAR Res. 2008; 2008: 247379. Published online 2008 June 12. doi: 10.1155/2008/247379.
PMCID: PMC2430014
Chondrosarcoma and Peroxisome Proliferator-Activated Receptor
K. Nishida, T. Kunisada, Z. N. Shen, Y. Kadota, K. Hashizume, and T. Ozaki
PPAR Res. 2008; 2008: 250568. Published online 2008 August 17. doi: 10.1155/2008/250568.
PMCID: PMC2517661
The PPARequation M1-PGC-1equation M2 Axis Controls Cardiac Energy Metabolism in Healthy and Diseased Myocardium
Jennifer G. Duncan and Brian N. Finck
PPAR Res. 2008; 2008: 253817. Published online 2007 November 25. doi: 10.1155/2008/253817.
PMCID: PMC2225461
Activated PPARγ Targets Surface and Intracellular Signals That Inhibit the Proliferation of Lung Carcinoma Cells
Shou Wei Han and Jesse Roman
PPAR Res. 2008; 2008: 254108. Published online 2008 August 13. doi: 10.1155/2008/254108.
PMCID: PMC2515882
Mitochondria, PPARs, and Cancer: Is Receptor-Independent Action of PPAR Agonists a Key?
Roberto Scatena, Patrizia Bottoni, and Bruno Giardina
PPAR Res. 2008; 2008: 256251. Published online 2008 July 14. doi: 10.1155/2008/256251.
PMCID: PMC2464819
Peroxisome Proliferator-Activated Receptors in the Modulation of the Immune/Inflammatory Response in Atherosclerosis
Ana Z. Fernandez
PPAR Res. 2008; 2008: 285842. Published online 2008 August 21. doi: 10.1155/2008/285842.
PMCID: PMC2519138
The Role of NF-κB in PPARα-Mediated Hepatocarcinogenesis
Howard P. Glauert, Karen Calfee-Mason, Yixin Li, Vani Nilakantan, Michelle L. Twaroski, Job Tharappel, and Brett T. Spear
PPAR Res. 2008; 2008: 286249. Published online 2009 January 29. doi: 10.1155/2008/286249.
PMCID: PMC2633453
PPARα/γ-Independent Effects of PPARα/γ Ligands on Cysteinyl Leukotriene Production in Mast Cells
Masamichi Yamashita
PPAR Res. 2008; 2008: 293538. Published online 2008 November 9. doi: 10.1155/2008/293538.
PMCID: PMC2581788
PPAR-γ, Microglial Cells, and Ocular Inflammation: New Venues for Potential Therapeutic Approaches
Fiorella Malchiodi-Albedi, Andrea Matteucci, Antonietta Bernardo, and Luisa Minghetti
PPAR Res. 2008; 2008: 295784. Published online 2008 March 11. doi: 10.1155/2008/295784.
PMCID: PMC2276614
TZDs and Bone: A Review of the Recent Clinical Evidence
Ann V. Schwartz
PPAR Res. 2008; 2008: 297893. Published online 2008 September 8. doi: 10.1155/2008/297893.
PMCID: PMC2532707
PPARγ and MEK Interactions in Cancer
Elke Burgermeister and Rony Seger
PPAR Res. 2008; 2008: 309469. Published online 2008 June 26. doi: 10.1155/2008/309469.
PMCID: PMC2440494
A Role for the PPARγ in Cancer Therapy
Moray J. Campbell, Carsten Carlberg, and H. Phillip Koeffler
PPAR Res. 2008; 2008: 314974. Published online 2008 May 28. doi: 10.1155/2008/314974.
PMCID: PMC2408680
The Role of PPAR-γ and Its Interaction with COX-2 in Pancreatic Cancer
Guido Eibl
PPAR Res. 2008; 2008: 326915. Published online 2008 July 2. doi: 10.1155/2008/326915.
PMCID: PMC2442877
The PPAR-Platelet Connection: Modulators of Inflammation and Potential Cardiovascular Effects
S. L. Spinelli, J. J. O'Brien, S. Bancos, G. M. Lehmann, D. L. Springer, N. Blumberg, C. W. Francis, M. B. Taubman, and R. P. Phipps
PPAR Res. 2008; 2008: 328172. Published online 2007 December 24. doi: 10.1155/2008/328172.
PMCID: PMC2233896
Role of Peroxisome Proliferator-Activated Receptor Alpha in the Control of Cyclooxygenase 2 and Vascular Endothelial Growth Factor: Involvement in Tumor Growth
Raquel Grau, Manuel D. Díaz-Muñoz, Cristina Cacheiro-Llaguno, Manuel Fresno, and Miguel A. Iñiguez
PPAR Res. 2008; 2008: 352437. Published online 2008 July 28. doi: 10.1155/2008/352437.
PMCID: PMC2490577
Omega-3 Fatty Acids and PPARγ in Cancer
Iris J. Edwards and Joseph T. O'Flaherty
PPAR Res. 2008; 2008: 358052. Published online 2008 August 27. doi: 10.1155/2008/358052.
PMCID: PMC2526161
Peroxisome Proliferator-Activated Receptors as Mediators of Phthalate-Induced Effects in the Male and Female Reproductive Tract: Epidemiological and Experimental Evidence
Giuseppe Latini, Egeria Scoditti, Alberto Verrotti, Claudio De Felice, and Marika Massaro
PPAR Res. 2008; 2008: 359267. Published online 2007 December 6. doi: 10.1155/2008/359267.
PMCID: PMC2225463
Hexarelin Signaling to PPARequation M1 in Metabolic Diseases
Annie Demers, Amélie Rodrigue-Way, and André Tremblay
PPAR Res. 2008; 2008: 364784. Published online 2008 January 2. doi: 10.1155/2008/364784.
PMCID: PMC2233980
PPAR Genomics and Pharmacogenomics: Implications for Cardiovascular Disease
Sharon Cresci
PPAR Res. 2008; 2008: 374549. Published online 2008 March 24. doi: 10.1155/2008/374549.
PMCID: PMC2288645
Peroxisome Proliferator-Activated Receptor and Age-Related Macular Degeneration
Alexandra A. Herzlich, Jingsheng Tuo, and Chi-Chao Chan
PPAR Res. 2008; 2008: 389507. Published online 2008 January 27. doi: 10.1155/2008/389507.
PMCID: PMC2234091
PPARs in Alzheimer's Disease
Markus P. Kummer and Michael T. Heneka
PPAR Res. 2008; 2008: 403896. Published online 2008 July 14. doi: 10.1155/2008/403896.
PMCID: PMC2465016
Peroxisome Proliferator-Activated Receptor-γ in Amyotrophic Lateral Sclerosis and Huntington's Disease
Mahmoud Kiaei
PPAR Res. 2008; 2008: 418765. Published online 2008 April 24. doi: 10.1155/2008/418765.
PMCID: PMC2366134
Transcriptional Control of Vascular Smooth Muscle Cell Proliferation by Peroxisome Proliferator-Activated Receptor-equation M1: Therapeutic Implications for Cardiovascular Diseases
Florence Gizard and Dennis Bruemmer
PPAR Res. 2008; 2008: 429123. Published online 2007 December 6. doi: 10.1155/2008/429123.
PMCID: PMC2225465
Peroxisome Proliferator-Activated Receptor-γ Ligands: Potential Pharmacological Agents for Targeting the Angiogenesis Signaling Cascade in Cancer
Costas Giaginis, Anna Tsantili-Kakoulidou, and Stamatios Theocharis
PPAR Res. 2008; 2008: 431763. Published online 2008 April 23. doi: 10.1155/2008/431763.
PMCID: PMC2366048
PPARγ: The Portrait of a Target Ally to Cancer Chemopreventive Agents
Ioannis Sainis, Katerina Vareli, Vasilios Karavasilis, and Evangelos Briasoulis
PPAR Res. 2008; 2008: 436489. Published online 2008 September 3. doi: 10.1155/2008/436489.
PMCID: PMC2528242
The Roles of PPARs in the Fetal Origins of Metabolic Health and Disease
William D. Rees, Christopher J. McNeil, and Christopher A. Maloney
PPAR Res. 2008; 2008: 459030. Published online 2008 January 15. doi: 10.1155/2008/459030.
PMCID: PMC2234254
Therapeutic Potential of PPARγ Activation in Stroke
Raghu Vemuganti
PPAR Res. 2008; 2008: 461981. Published online 2008 April 13. doi: 10.1155/2008/461981.
PMCID: PMC2293414
Potential Therapeutic Use of PPARγ-Programed Human Monocyte-Derived Dendritic Cells in Cancer Vaccination Therapy
Adrienn Gyöngyösi and László Nagy
PPAR Res. 2008; 2008: 473804. Published online 2008 November 5. doi: 10.1155/2008/473804.
PMCID: PMC2581789
Potential of Peroxisome Proliferator-Activated Receptor Gamma Antagonist Compounds as Therapeutic Agents for a Wide Range of Cancer Types
Jack D. Burton, David M. Goldenberg, and Rosalyn D. Blumenthal
PPAR Res. 2008; 2008: 494161. Published online 2008 September 2. doi: 10.1155/2008/494161.
PMCID: PMC2528255
The Critical Role of PPARγ in Human Malignant Melanoma
Christian Freudlsperger, Udo Schumacher, Siegmar Reinert, and Jürgen Hoffmann
PPAR Res. 2008; 2008: 503797. Published online 2008 May 11. doi: 10.1155/2008/503797.
PMCID: PMC2377344
PPAR Gamma Activators: Off-Target Against Glioma Cell Migration and Brain Invasion
Sebastian Seufert, Roland Coras, Christian Tränkle, Darius P. Zlotos, Ingmar Blümcke, Lars Tatenhorst, Michael T. Heneka, and Eric Hahnen
PPAR Res. 2008; 2008: 513943. Published online 2008 September 14. doi: 10.1155/2008/513943.
PMCID: PMC2542841
Potential Therapeutic Targets for PPARγ after Spinal Cord Injury
Dana M. McTigue
PPAR Res. 2008; 2008: 517162. Published online 2008 March 27. doi: 10.1155/2008/517162.
PMCID: PMC2288640
Pioglitazone versus Rosiglitazone: Effects on Lipids, Lipoproteins, and Apolipoproteins in Head-to-Head Randomized Clinical Studies
Mark A. Deeg and Meng H. Tan
PPAR Res. 2008; 2008: 520465. Published online 2008 August 21. doi: 10.1155/2008/520465.
PMCID: PMC2519139
The Role of PPAR Ligands in Controlling Growth-Related Gene Expression and their Interaction with Lipoperoxidation Products
Giuseppina Barrera, Cristina Toaldo, Stefania Pizzimenti, Angelo Cerbone, Piergiorgio Pettazzoni, Mario Umberto Dianzani, and Carlo Ferretti
PPAR Res. 2008; 2008: 524671. Published online 2008 July 6. doi: 10.1155/2008/524671.
PMCID: PMC2443425
PPAR Action in Human Placental Development and Pregnancy and Its Complications
Fritz Wieser, Leslie Waite, Christophe Depoix, and Robert N. Taylor
PPAR Res. 2008; 2008: 527048. Published online 2007 December 30. doi: 10.1155/2008/527048.
PMCID: PMC2234270
The Roles of Dietary PPARγ Ligands for Metastasis in Colorectal Cancer
Hiroki Kuniyasu
PPAR Res. 2008; 2008: 529720. Published online 2008 June 5. doi: 10.1155/2008/529720.
PMCID: PMC2422868
A Role for PPARβ/δ in Tumor Stroma and Tumorigenesis
Rolf Müller, Martin Kömhoff, Jeffrey M. Peters, and Sabine Müller-Brüsselbach
PPAR Res. 2008; 2008: 534294. Published online 2008 May 15. doi: 10.1155/2008/534294.
PMCID: PMC2390718
Peroxisome Proliferator-Activated Receptors: “Key” Regulators of Neuroinflammation after Traumatic Brain Injury
Philip F. Stahel, Wade R. Smith, Jay Bruchis, and Craig H. Rabb
PPAR Res. 2008; 2008: 538141. Published online 2008 March 27. doi: 10.1155/2008/538141.
PMCID: PMC2276625
PPARγ and Proline Oxidase in Cancer
James M. Phang, Jui Pandhare, Olga Zabirnyk, and Yongmin Liu
PPAR Res. 2008; 2008: 542694. Published online 2008 July 28. doi: 10.1155/2008/542694.
PMCID: PMC2490722
PPAR Alpha Regulation of the Immune Response and Autoimmune Encephalomyelitis
Yuhong Yang, Anne R. Gocke, Amy Lovett-Racke, Paul D. Drew, and Michael K. Racke
PPAR Res. 2008; 2008: 546753. Published online 2008 July 14. doi: 10.1155/2008/546753.
PMCID: PMC2465123
PPAR-γ Thiazolidinedione Agonists and Immunotherapy in the Treatment of Brain Tumors
Terry Lichtor, Alessandra Spagnolo, Roberta P. Glick, and Douglas L. Feinstein
PPAR Res. 2008; 2008: 547470. Published online 2008 May 22. doi: 10.1155/2008/547470.
PMCID: PMC2396217
PPAR Ligands for Cancer Chemoprevention
Yumiko Yasui, Mihye Kim, and Takuji Tanaka
PPAR Res. 2008; 2008: 548919. Published online 2008 May 11. doi: 10.1155/2008/548919.
PMCID: PMC2377329
Do PPARγ Ligands Suppress the Growth of Cholangiocarcinoma or the Cholangiohepatitis Induced by the Tumor?
Satoru Suzuki and Kiyoshi Hashizume
PPAR Res. 2008; 2008: 587401. Published online 2008 July 6. doi: 10.1155/2008/587401.
PMCID: PMC2443545
Regulation of Cell Proliferation and Differentiation by PPARβ/δ
Rolf Müller, Markus Rieck, and Sabine Müller-Brüsselbach
PPAR Res. 2008; 2008: 614852. Published online 2008 September 16. doi: 10.1155/2008/614852.
PMCID: PMC2542843
PPAR-γ: Therapeutic Potential for Multiple Sclerosis
Paul D. Drew, Jihong Xu, and Michael K. Racke
PPAR Res. 2008; 2008: 627463. Published online 2008 June 29. doi: 10.1155/2008/627463.
PMCID: PMC2441778
Protective Actions of PPAR-γ Activation in Renal Endothelium
Peter E. Westerweel and Marianne C. Verhaar
PPAR Res. 2008; 2008: 635680. Published online 2009 February 26. doi: 10.1155/2008/635680.
PMCID: PMC2650079
PPAR Regulation of Inflammatory Signaling in CNS Diseases
John J. Bright, Saravanan Kanakasabai, Wanida Chearwae, and Sharmistha Chakraborty
PPAR Res. 2008; 2008: 658520. Published online 2008 July 28. doi: 10.1155/2008/658520.
PMCID: PMC2490815
The Role of the PAX8/PPARγ Fusion Oncogene in Thyroid Cancer
Kimberly A. Placzkowski, Honey V. Reddi, Stefan K. G. Grebe, Norman L. Eberhardt, and Bryan McIver
PPAR Res. 2008; 2008: 672829. Published online 2008 October 29. doi: 10.1155/2008/672829.
PMCID: PMC2579323
Peroxisome Proliferators-Activated Receptor (PPAR) Modulators and Metabolic Disorders
Min-Chul Cho, Kyoung Lee, Sang-Gi Paik, and Do-Young Yoon
PPAR Res. 2008; 2008: 679137. Published online 2008 June 15. doi: 10.1155/2008/679137.
PMCID: PMC2430035
Role of Peoxisome Proliferator Activator Receptor equation M1 on Blood Retinal Barrier Breakdown
Yasuo Yanagi
PPAR Res. 2008; 2008: 679237. Published online 2008 January 27. doi: 10.1155/2008/679237.
PMCID: PMC2248243
Structural Development Studies of Subtype-Selective Ligands for Peroxisome Proliferator-Activated Receptors (PPARs) Based on the 3,4-Disubstituted Phenylpropanoic Acid Scaffold as a Versatile Template
Hiroyuki Miyachi and Yuichi Hashimoto
PPAR Res. 2008; 2008: 689859. Published online 2008 June 15. doi: 10.1155/2008/689859.
PMCID: PMC2430034
PPARγ and Apoptosis in Cancer
Heath A. Elrod and Shi-Yong Sun
PPAR Res. 2008; 2008: 704165. Published online 2008 July 2. doi: 10.1155/2008/704165.
PMCID: PMC2442903
Prevention of Oxidative Stress-Induced Retinal Pigment Epithelial Cell Death by the PPARγ Agonists, 15-Deoxy-Delta 12, 14-Prostaglandin J2
Jason Y. Chang, Puran S. Bora, and Nalini S. Bora
PPAR Res. 2008; 2008: 720163. Published online 2008 March 16. doi: 10.1155/2008/720163.
PMCID: PMC2276681
PPARs and Female Reproduction: Evidence from Genetically Manipulated Mice
Jichun Yang, Lihong Chen, Xiaoyan Zhang, Yunfeng Zhou, Dongjuan Zhang, Ming Huo, and Youfei Guan
PPAR Res. 2008; 2008: 723243. Published online 2008 April 6. doi: 10.1155/2008/723243.
PMCID: PMC2288756
The Role of Peroxisome Proliferator-Activated Receptors in the Development and Physiology of Gametes and Preimplantation Embryos
Jaou-Chen Huang
PPAR Res. 2008; 2008: 732303. Published online 2008 February 28. doi: 10.1155/2008/732303.
PMCID: PMC2266973
PPAR-equation M1 in the Cardiovascular System
Sheng Zhong Duan, Christine Y. Ivashchenko, Michael G. Usher, and Richard M. Mortensen
PPAR Res. 2008; 2008: 745804. Published online 2007 December 6. doi: 10.1155/2008/745804.
PMCID: PMC2225467
Screening for PPAR Responsive Regulatory Modules in Cancer
Merja Heinäniemi and Carsten Carlberg
PPAR Res. 2008; 2008: 749073. Published online 2008 June 5. doi: 10.1155/2008/749073.
PMCID: PMC2422871
Combination Therapy of PPARγ Ligands and Inhibitors of Arachidonic Acid in Lung Cancer
Jordi Tauler and James L. Mulshine
PPAR Res. 2008; 2008: 750238. Published online 2009 March 4. doi: 10.1155/2008/750238.
PMCID: PMC2652614
Placental Implications of Peroxisome Proliferator-Activated Receptors in Gestation and Parturition
Valerie Borel, Denis Gallot, Geoffroy Marceau, Vincent Sapin, and Loïc Blanchon
PPAR Res. 2008; 2008: 758562. Published online 2008 January 20. doi: 10.1155/2008/758562.
PMCID: PMC2234353
PPARα- and DEHP-Induced Cancers
Yuki Ito and Tamie Nakajima
PPAR Res. 2008; 2008: 759716. Published online 2008 August 31. doi: 10.1155/2008/759716.
PMCID: PMC2527472
A Novel Mechanism of PPARγ Regulation of TGFβ1: Implication in Cancer Biology
Chang Ho Lee, Hyung Don Kim, Sang Mi Shin, and Sang Geon Kim
PPAR Res. 2008; 2008: 762398. Published online 2008 July 3. doi: 10.1155/2008/762398.
PMCID: PMC2443397
CXCR4 in Cancer and Its Regulation by PPARγ
Cynthia Lee Richard and Jonathan Blay
PPAR Res. 2008; 2008: 769413. Published online 2008 September 2. doi: 10.1155/2008/769413.
PMCID: PMC2528256
Peroxisome Proliferator-Activated Receptor β/δ in the Brain: Facts and Hypothesis
M. G. Hall, Laure Quignodon, and Béatrice Desvergne
PPAR Res. 2008; 2008: 780452. Published online 2008 November 9. doi: 10.1155/2008/780452.
PMCID: PMC2581793
PPARγ Inhibitors as Novel Tubulin-Targeting Agents
Katherine L. Schaefer
PPAR Res. 2008; 2008: 785405. Published online 2008 May 26. doi: 10.1155/2008/785405.
PMCID: PMC2396401
The Role of PPARγ in the Cyclooxygenase Pathway in Lung Cancer
Saswati Hazra, Katherine A. Peebles, Sherven Sharma, Jenny T. Mao, and Steven M. Dubinett
PPAR Res. 2008; 2008: 790568. Published online 2008 August 27. doi: 10.1155/2008/790568.
PMCID: PMC2526169
The Potential Applications of Peroxisome Proliferator-Activated Receptor δ Ligands in Assisted Reproductive Technology
Jaou-Chen Huang
PPAR Res. 2008; 2008: 794814. Published online 2008 December 16. doi: 10.1155/2008/794814.
PMCID: PMC2603272
PPAR-α Ligands as Potential Therapeutic Agents for Wet Age-Related Macular Degeneration
Marisol del V Cano and Peter L. Gehlbach
PPAR Res. 2008; 2008: 821592. Published online 2008 April 6. doi: 10.1155/2008/821592.
PMCID: PMC2288686
A Role for PPARβ/δ in Ocular Angiogenesis
David Bishop-Bailey
PPAR Res. 2008; 2008: 825970. Published online 2008 March 11. doi: 10.1155/2008/825970.
PMCID: PMC2276600
The Role of PPARγ Receptors and Leukotriene B4 Receptors in Mediating the Effects of LY293111 in Pancreatic Cancer
Thomas E. Adrian, Rene Hennig, Helmut Friess, and Xianzhong Ding
PPAR Res. 2008; 2008: 827096. Published online 2009 January 27. doi: 10.1155/2008/827096.
PMCID: PMC2631651
Role of Peroxisome Proliferator-Activated Receptor Gamma and Its Ligands in the Treatment of Hematological Malignancies
Tatiana M. Garcia-Bates, Geniece M. Lehmann, Patricia J. Simpson-Haidaris, Steven H. Bernstein, Patricia J. Sime, and Richard P. Phipps
PPAR Res. 2008; 2008: 834612. Published online 2008 May 26. doi: 10.1155/2008/834612.
PMCID: PMC2408681
Regulation of Glial Cell Functions by PPAR-γ Natural and Synthetic Agonists
Antonietta Bernardo and Luisa Minghetti
PPAR Res. 2008; 2008: 864140. Published online 2008 April 22. doi: 10.1155/2008/864140.
PMCID: PMC2367430
Peroxisome Proliferator-Activated Receptors in Diabetic Nephropathy
Shinji Kume, Takashi Uzu, Keiji Isshiki, and Daisuke Koya
PPAR Res. 2008; 2008: 879523. Published online 2009 March 4. doi: 10.1155/2008/879523.
PMCID: PMC2652581
Should We Use PPAR Agonists to Reduce Cardiovascular Risk?
Jennifer G. Robinson
PPAR Res. 2008; 2008: 891425. Published online 2008 January 28. doi: 10.1155/2008/891425.
PMCID: PMC2234387
Regulation of Lymphocyte Function by PPARγ: Relevance to Thyroid Eye Disease-Related Inflammation
G. M. Lehmann, T. M. Garcia-Bates, T. J. Smith, S. E. Feldon, and R. P. Phipps
PPAR Res. 2008; 2008: 895901. Published online 2008 March 2. doi: 10.1155/2008/895901.
PMCID: PMC2266979
The Role of PPARs in the Endothelium: Implications for Cancer Therapy
David Bishop-Bailey and Karen E. Swales
PPAR Res. 2008; 2008: 904251. Published online 2008 November 24. doi: 10.1155/2008/904251.
PMCID: PMC2586817
PPARα Ligands as Antitumorigenic and Antiangiogenic Agents
Ambra Pozzi and Jorge H. Capdevila
PPAR Res. 2008; 2008: 906542. Published online 2008 August 14. doi: 10.1155/2008/906542.
PMCID: PMC2517125
PPARγ in Neuroblastoma
Alessandro Peri, Ilaria Cellai, Susanna Benvenuti, Paola Luciani, Silvana Baglioni, and Mario Serio
PPAR Res. 2008; 2008: 917815. Published online 2008 May 28. doi: 10.1155/2008/917815.
PMCID: PMC2397449
NO-Donating NSAIDs, PPARδ, and Cancer: Does PPARδ Contribute to Colon Carcinogenesis?
Gerardo G. Mackenzie, Shaheen Rasheed, William Wertheim, and Basil Rigas
PPAR Res. 2008; 2008: 919572. Published online 2008 May 29. doi: 10.1155/2008/919572.
PMCID: PMC2408682
Anticancer Properties of PPARα-Effects on Cellular Metabolism and Inflammation
Maja Grabacka and Krzysztof Reiss
PPAR Res. 2008; 2008: 930705. Published online 2008 May 20. doi: 10.1155/2008/930705.
PMCID: PMC2396219
Peroxisome Proliferator-Activated Receptors and Progression of Colorectal Cancer
Dingzhi Wang and Raymond N. DuBois
PPAR Res. 2008; 2008: 931074. Published online 2008 June 5. doi: 10.1155/2008/931074.
PMCID: PMC2422873
PPARγ, PTEN, and the Fight against Cancer
Rosemary E. Teresi and Kristin A. Waite
PPAR Res. 2008; 2008: 932632. Published online 2008 December 14. doi: 10.1155/2008/932632.
PMCID: PMC2602868
The Development of INT131 as a Selective PPARγ Modulator: Approach to a Safer Insulin Sensitizer
Linda S. Higgins and Christos S. Mantzoros
PPAR Res. 2008; 2008: 936906. Published online 2008 August 26. doi: 10.1155/2008/936906.
PMCID: PMC2522386
Renal and Vascular Mechanisms of Thiazolidinedione-Induced Fluid Retention
Tianxin Yang and Sunhapas Soodvilai
PPAR Res. 2008; 2008: 943614. Published online 2008 September 7. doi: 10.1155/2008/943614.
PMCID: PMC2531205
PPARγ and Agonists against Cancer: Rational Design of Complementation Treatments
Dorina Veliceasa, Frank Thilo Schulze-Hoëpfner, and Olga V. Volpert
PPAR Res. 2008; 2008: 945275. Published online 2008 November 18. doi: 10.1155/2008/945275.
PMCID: PMC2586323
A Role for PPARγ in the Regulation of Cytokines in Immune Cells and Cancer
Xiao Yi Yang, Li Hua Wang, and William L. Farrar
PPAR Res. 2008; 2008: 961753. Published online 2008 June 12. doi: 10.1155/2008/961753.
PMCID: PMC2430015
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